Preparation and Optimization of Polymer-Supported and Amino Alcohol Based Enantioselective Reagents and Catalysts

Industrial and Engineering Chemistry Research

Volumn 42, Issue 24, 2003, Pages 5977-5982

  Luis, S V ^a   Altava, B ^a   Burguete, M I ^a   Collado, M ^a   Escorihuela, J ^a   Garcia Verdugo E ^a   Vicent, M J ^a   Martens, J ^b  

^a UNIVERSITAT JAUME I   (Spain)

^b UNIVERSITY OF OLDENBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDES; CATALYST ACTIVITY; MOLECULAR STRUCTURE;

CHIRAL COMPOUNDS;

ALCOHOLS;

ACETOPHENONE; ALUMINUM DERIVATIVE; ALUMINUM LITHIUM HYDRIDE; AMINOALCOHOL; BENZALDEHYDE; POLYMER; REAGENT; UNCLASSIFIED DRUG; ZINC DERIVATIVE;

CATALYSIS;

ADDITION REACTION; CATALYSIS; CATALYST; CHEMICAL STRUCTURE; CHIRALITY; COMBINATORIAL CHEMISTRY; CONFERENCE PAPER; ENANTIOSELECTIVITY; METHODOLOGY; REACTION ANALYSIS; REDUCTION; STRUCTURE ANALYSIS;

EID: 0345356952     PISSN: 08885885     EISSN: None     Source Type: Journal    
DOI: 10.1021/ie030150t     Document Type: Conference Paper

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55. 2.
56. 3) using the following signals (δ): benzaldehyde (9.9, s, 1H); 1-phenyl-1-propanol (4.45, t, 1H); benzyl alcohol (4.65, s, 2H). The enantiomeric excess was determined by the use of high-performance liquid chromatography (Chiralcel OD) using a mixture of n-hexane-i-propanol (97:3) as the eluent (1 mL/min), (R)-1-phenyl-1-propanol (room temperature, 10.48 min), and (S)-1-phenyl-1-propanol (room temperature, 12.64 min).