N6-Cycloalkyl-2-phenyl-3-deaza-8-azaadenines: A new class of A1 adenosine receptor ligands. A comparison with the corresponding adenines and 8-azaadenines

European Journal of Medicinal Chemistry

Volumn 38, Issue 11-12, 2003, Pages 983-990

  Biagi, Giuliana ^a   Giorgi, Irene ^a   Livi, Oreste ^a   Nardi, Antonio ^a   Pacchini, Federica ^a   Scartoni, Valerio ^a   Lucacchini, Antonio ^a  

^a UNIVERSITY OF PISA   (Italy)

Author keywords

4 Cycloalkylamino 1 benzyl 6 phenyl 1H 1,2,3 triazolo 4,5 c pyridines; 9 Benzyl N6 cycloalkyl 2 phenyladenines; 9 Benzyl N6 cycloalkyl 2 phenyl 8 azaadenines; A1 Adenosine receptor ligands; Bioisosterism

Indexed keywords

1 BENZYL 6 PHENYL 1H 1,2,3 TRIAZOLO[4,5 C]PYRIDIN 4 ONE; 8 AZAADENINE; ADENINE DERIVATIVE; ADENOSINE A1 RECEPTOR; ALIPHATIC AMINE; ANHYDROUS TETRAHYDROFURANE; BENZONITRILE; CHEMICAL COMPOUND; ESTER DERIVATIVE; FURAN DERIVATIVE; LIGAND; N,N DIETHYL 1 BENZYL 4 CARBOXAMIDO 5 METHYL 1H 1,2,3 TRIAZOLE; PHOSPHOROUS OXYCHLORIDE; PHOSPHORUS DERIVATIVE; PYRIDINE DERIVATIVE; TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG; 8-AZAADENINE; ADENINE; DRUG DERIVATIVE;

ARTICLE; BINDING AFFINITY; DRUG MECHANISM; DRUG RECEPTOR BINDING; LIPOPHILICITY; LITHIATION; PROTEIN DETERMINATION; RECEPTOR BINDING; ANIMAL; BRAIN; CATTLE; CHEMISTRY; COMPARATIVE STUDY; METABOLISM; PHYSIOLOGY; PROTEIN BINDING;

ADENINE; ANIMALS; BRAIN; CATTLE; LIGANDS; PROTEIN BINDING; RECEPTOR, ADENOSINE A1;

EID: 0345306232     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejmech.2003.09.003     Document Type: Article

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