Bioisosterism, enantioselectivity, and molecular modeling of new effective N6- and/or N(9)-substituted 2-phenyl adenines and 8-aza analogs: Different binding modes to A1 adenosine receptors

Drug Development Research

Volumn 54, Issue 2, 2001, Pages 52-65

  Bianucci, A Maria ^a   Biagi, Giuliana ^a   Coi, Alessio ^a   Giorgi, Irene ^a   Oreste, Livi ^a   Pacchini, Federica ^a   Scartoni, Valerio ^a   Lucacchini, Antonio ^a   Costa, Barbara ^a  

^a UNIVERSITY OF PISA   (Italy)

Author keywords

Antagonists; Ligands; Stereoselectivity

Indexed keywords

2 PHENYLADENINE DERIVATIVE; 8 AZAADENINE DERIVATIVE; ADENINE DERIVATIVE; ADENOSINE A1 RECEPTOR; ADENOSINE A1 RECEPTOR ANTAGONIST; ADENOSINE A2 RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CALCULATION; CHIRALITY; CONTROLLED STUDY; DRUG ACTIVITY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOMER; ENERGY; MOLECULAR INTERACTION; MOLECULAR MODEL; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION; THEORY;

EID: 0035671434     PISSN: 02724391     EISSN: None     Source Type: Journal    
DOI: 10.1002/ddr.1205     Document Type: Article

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