The mouse cpp32 mRNA transcript is early up-regulated in axotomized motoneurons following facial nerve transection

Neuroscience Letters

Volumn 266, Issue 1, 1999, Pages 65-68

  De Bilbao, Fabienne ^a   Guarin, Ernesto ^b   Nef, Patrick ^b   Dubois Dauphin, Michel ^a  

^a GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^b F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

Apoptosis; Bcl 2 family; Caspase; Mice; Motoneurone; Neurodegeneration

Indexed keywords

CASPASE 3; MESSENGER RNA; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL X;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTORADIOGRAPHY; FACIAL NERVE; MOTONEURON; MOUSE; NERVE FIBER TRANSECTION; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; RNA ANALYSIS; TRANSCRIPTION REGULATION;

ANIMALS; AUTORADIOGRAPHY; AXOTOMY; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; CASPASE 3; CASPASES; ENZYME PRECURSORS; FACIAL NERVE; GENES, BCL-2; IN SITU HYBRIDIZATION; KINETICS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MOTOR NEURONS; NERVE DEGENERATION; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RNA, MESSENGER; UP-REGULATION;

EID: 0345280017     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(99)00264-5     Document Type: Article

References (15)

1. Chen J., Nagayama T., Jin K., Stetler R.A., Zhu R.L., Graham S.H., Simon R.P. Induction of caspase-3-like protease may mediate delayed neuronal death in the hippocampus after transient cerebral ischemia. J. Neurosci. 18:1998;4914-4928.
2. de Bilbao F., Dubois-Dauphin M. Time course of axotomy-induced cell death in facial motoneurons of neonatal wild type and Bcl-2 transgenic mice. Neuroscience. 71:1996;1111-1119.
3. de Bilbao F., Dubois-Dauphin M. Acute application of an interleukin-1(-converting enzyme-specific inhibitor delays axotomy-induced motoneurone death. NeuroReport. 7:1996;3051-3054.
4. Deckwerth T.L., Elliott J.L., Knudson C.M., Johnson E.M., Snider W.D., Korsmeyer S.J. Bax is required for neuronal death after trophic factor deprivation and during development. Neuron. 17:1996;401-411.
5. Dubois-Dauphin M., Frankowski H., Tsujimoto Y., Huarte J., Martinou J.C. Neonatal motoneurons overexpressing the Bcl-2 protooncogene in transgenic mice are protected from axotomy-induced cell death. Proc. Natl. Acad. Sci. USA. 91:1994;3309-3313.
6. Guarin E., Seuret P., Nef S., de Bilbao F., Nef P., Dubois-Dauphin M. Cpp32 messenger RNA neosynthesis is induced by fatal axotomy and is not regulated by athanatal BCL-2 over-expression. Neuroscience. 2:1999;653-654.
7. Haas C.A., Donath C., Kreutzberg G.W. Differential expression of immediate early genes after transection of the facial nerve. Neuroscience. 53:1993;91-99.
8. Holtzman D.M., Deshmukh M. Caspases: a treatment target for neurodegenerative disease? Nat. Med. 3:1997;954-955.
9. Hoover D.B., Hancock J.C. Effect of facial nerve transection on acetylcholinesterase, choline acetyltransferase and (3H(quinuclidinyl benzilate binding in rat facial nuclei. Neuroscience. 15:1985;481-487.
10. Kuida K., Zheng T.S., Na S., Kuan C.Y., Yang D., Karasuyama H., Rakic P., Flavell R.A. Decreased apoptosis in the brain and premature lethality in cpp32-deficient mice. Nature. 384:1996;368-372.
11. Motoyama N., Wang F., Roth K.A., Sawa H., Nakayama K.I., Nakayama K., Negishi I., Senju S., Zhang Q., Fujii S., Loh D.Y. Massive cell death of immature hematopoietic cells and neurons in bcl-x-deficient mice. Science. 267:1995;1506-1510.
12. Newton K., Strasser A. The Bcl-2 family and cell death regulation. Curr. Opin. Gen. Dev. 8:1998;68-75.
13. Parsadanian A.Sh., Cheng Y., Keller-Peck C.R., Holtzman, D.M., Snider W.D. Bcl-xl is an apoptotic regulator for postnatal CNS neurons. J. Neurosci. 18:1998;1009-1019.
14. Schwaiger F.W., Hager G., Horvat A., Hager G., Streif R., Kreutzberg G.W. Activation and Regulation of Signal Transducers and Activators of Transcription in Response to Facial Nerve Axotomy (Abstract book). 1998;European Neuroscience Congress, Berlin. p. 60.
15. White F.A., Keller-Peck C.R., Knudson C.M., Korsmeyer S.J., Snider W.D. Widespread elimination of naturally occurring neuronal death in bax-deficient mice. J. Neurosci. 18:1998;1428-1439.