cpp32 Messenger RNA neosynthesis is induced by fatal axotomy and is not regulated by athanatal Bcl-2 over-expression

Neuroscience

Volumn 90, Issue 2, 1999, Pages 653-664

  Guarin, E ^a   Seuret, P ^a   Nef, S ^a   De Bilbao, F ^b   Nef, P ^a   Dubois Dauphin, M ^b  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

Apoptosis; Axotomy; Bax; Bcl 2; Cpp32; Motoneurons

Indexed keywords

PROTEIN BCL 2;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; MOTONEURON; MOUSE; NERVE FIBER TRANSECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA SYNTHESIS; TRANSGENIC MOUSE;

ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; AXOTOMY; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; CASPASE 3; CASPASES; FACIAL NERVE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENES, BCL-2; HUMANS; IN SITU HYBRIDIZATION; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MOTOR NEURONS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RNA, MESSENGER; TRANSCRIPTION, GENETIC;

EID: 0032936467     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(98)00445-X     Document Type: Article

References (44)

1. Alberi S., Raggenbass M., de Bilbao F., Dubois-Dauphin M. Axotomized neonatal motoneurons overexpressing the bcl-2 proto-oncogene retain functional electrophysiological properties. Proc. natn. Acad. Sci. U.S.A. 93:1996;3978-3983.
2. Antonsson B., Conti F., Ciavatta A., Montessuit S., Lewis S., Martinou I., Bernasconi L., Bernard A., Mermod J.J., Mazzei G., Maundrell K., Gambale F., Sadoul R., Martinou J.C. Inhibition of Bax channel-forming activity by Bcl-2. Science. 27:1997;370-372.
3. Bisby M.A., Tetzlaff W., Brown M.C. Cell body response to injury in motoneurons and primary sensory neurons of a mutant mouse Ola (Wld) in which wallerian degeneration is delayed. J. comp. Neurol. 359:1995;653-662.
4. Chen S., Bisby M.A. Impaired motor axon regeneration in the C57Bl/Ola mouse. J. comp. Neurol. 333:1993;449-454.
5. Cheng E.H.-Y., Kirsch D.G., Clem R.J., Ravi R., Kastan M.B., Bedi A., Ueno K., Harwick J.M. Conversion of Bcl-2 to Bax-like death effector by caspases. Science. 278:1997;1966-1968.
6. Clem R.J., Cheng E.H.-Y., Karp Cl., Kirsch D.G., Ueno K., Takahashi A., Kastan M.B., Griffin D.E., Earnshaw W.C., Veliuona M.A., Harwick J.M. Modulation of cell death by Bcl-xl through caspase interaction. Proc. natn. Acad. Sci. U.S.A. 95:1997;554-559.
7. de Bilbao F., Dubois-Dauphin M. Time course of axotomy-induced cell death in facial motoneurons of neonatal wild type and Bcl-2 transgenic mice. Neuroscience. 71:1996;1111-1119.
8. de Bilbao F., Dubois-Dauphin M. Acute application of an interleukin-1β-converting enzyme-specific inhibitor delays axotomy-induced motoneurone death. NeuroReport. 1:1996;3051-3054.
9. Deckwerth T.L., Elliott J.L., Knudson C.M., Johnson E.M. Jr., Snider W.D., Korsemeyer S.J. Bax is required for neuronal death after trophic factor deprivation and during development. Neuron. 17:1996;401-411.
10. Dubois-Dauphin M., Frankowski H., Tsujimoto Y., Huarte J., Martinou J.C. Neonatal motoneurons overexpressing the bcl-2 proto-oncogene in transgenic mice are protected from axotomy-induced cell death. Proc. natn. Acad. Sci. U.S.A. 91:1994;3309-3313.
11. Friedlander R.M., Brown R.H., Gagliardini V., Wang J., Yuan J. Inhibition of ICE slows ALS in mice. Nature. 388:1997;31.
12. Gillardon F., Zimmermann M., Uhlman E., Krajewski S., Reed J.C., Klimaschewski L. Antisense oligodeoxynucleotides to bax mRNA promote survival of rat sympathetic neurons in culture. J. Neurosci. Res. 43:1996;726-734.
13. Gonzalez-Garcia M., Pérez-Ballestero R., Ding L., Duan L., Boise L.H., Thompson C.B., Nunez G. bcl-xl is the major bcl-x mRNA form expressed during murine development and its product localizes to mitochondria. Development. 120:1994;3033-3042.
14. Knudson C.M., Tung K.S. K., Tourtellotte W.G., Brown G.A. J., Korsemeyer S.J. Bax-deficient mice with lymphoid hyperplasia and male germ cell death. Nature. 270:1995;96-99.
15. Korhonen L., Hamner S., Olsson P.-A., Lindholm D. Bcl-2 regulates the level of cystein proteases ICH and CPP32/Yama in human precursor cells. Eur. J. Neurosci. 9:1997;2489-2496.
16. Kostic V., Jackson-Lewis V., de Bilbao F., Dubois-Dauphin M., Przedborski S. Bcl-2: prolonging life in a transgenic mouse model of familial amyotrophic lateral sclerosis. Science. 277:1997;559-562.
17. Krajewska M., Wang H.G., Krajewski S., Zapata J.M., Shabaik A., Gascoyne R., Reed J.C. Immunohistochemical analysis of in vivo patterns expression of CPP32 (Caspase 3), a cell death protease. Cancer Res. 57:1997;1605-1613.
18. Krajewski S., Krajewska M., Shabaik A., Wang H.G., Irie S., Fong L., Reed J.C. Immunohistochemical analysis of in vivo patterns of Bcl-x expression. Cancer Res. 54:1994;5501-5507.
19. Kuida K., Zheng T., Na S., Kuan C., Yang D., Kartasuyama H., Rakic P., Flavell R.A. Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice. Nature. 384:1996;368-372.
20. Lee D.A., Zurawel R.H., Windebank A.J. Ciliary neurotrophic factor expression in Schwann cells is induced by axonal contact. J. Neurochem. 65:1995;564-568.
21. Li P., Nijhawan D., Budihardjo I., Srinivasula S.M., Ahmad M., Alnemri E.S., Wang X. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell. 91:1997;479-489.
22. Miller T.M., Moulder K.L., Knudson C.M., Creedon D.J., Deshmukh M., Korsemeyer S.J., Johnson E.M. Bax deletion further orders the cell death pathway in cerebellar granule cells and suggests a caspase-independent pathway to cell death. J. Cell Biol. 139:1997;205-217.
23. Monney L., Otter I., Olivier R., Ravn U., Mirzasaleh H., Fellay I., Poirier G.G., Borner C. Bcl-2 over-expression blocks activation of the death protease Cpp32/Yama/Apopain. Biochem. biophys. Res. Commun. 221:1996;340-345.
24. Motoyama N., Wang F., Roth K.A., Sawa H., Nakayama K.I., Nakayama K., Negishi I., Senju S., Zhang Q., Fujii S., Loh D. Massive cell death of immature hematopoietic cells and neurons in Bcl-x deficient mice. Science. 267:1995;1506-1510.
25. Nef S., Allaman I., Fiumelli H., De Castro E., Nef P. Olfaction in birds: differential embryonic expression of nine putative odorant receptor genes in the avian olfactory system. Mech. Dev. 55:1996;65-77.
26. Nicholson D.W., Ali A., Thornberry N.A., Vaillancourt J.P., Ding C.K., Gallant M., Gareau Y., Griffin P.R., Labelle M., Lazebnik Y.A., Munday N.A., Raju S.M., Smulson M.E., Yamin T.-T., Yu V.L., Miller D.K. Identification and inhibition of the ICE/Ced-3 protease necessary for mammalian apoptosis. Nature. 376:1995;37-43.
27. Oltvai Z.N., Korsmeyer S.J. Checkpoints of dueling dimers foil death wishes. Cell. 79:1994;189-192.
28. Parsadanian A. Sh., Cheng Y., Keller-Peck C.R., Holtzman D.M., Snider W.D. Bcl-xl is an antiapoptotic regulator for postnatal CNS neurons. J. Neurosci. 18:1998;1009-1019.
29. Pollin M.M., McHanwell S., Slater C.R. The effect of age on motor neurone death following axotomy in the mouse. Development. 112:1991;83-89.
30. Reaume A.G., Elliott J.L., Hoffman E.K., Kowall N.W., Ferrante R.J., Siwek D.F., Wilcox H.M., Flood D.G., Beal M.F., Brown R.H. Jr., Scott R.W., Snider W.D. Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury. Nature Genet. 13:1996;43-47.
31. Rossé T., Olivier R., Monney L., Rager M., Conus L., Fellay I., Jansen B., Borner C. Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c. Nature. 391:1998;496-499.
32. Roth K.A., Motoyama N., Loh D. Apoptosis of bcl-x-deficient telencephalic cells in vivo. J. Neurosci. 16:1996;1753-1758.
33. Rouayrenc J.-F., Boise L.H., Thompson C.B., Privat A., Patey G. Presence of the long and short forms of Bcl-x in several human and murine tissues. C. r. hebd. Sêanc. Acad. Sci., Paris. 318:1995;537-540.
34. Schlesinger P.H., Gross A., Yin X.-M., Yamamoto K., Saito M., Waksman G., Korsemeyer S.J. Comparison of the ion channel characteristics of proapoptotic Bax and antiapoptotic Bcl-2. Proc. natn. Acad. Sci. U.S.A. 94:1997;11357-11362.
35. Schulz J.B., Bremen D., Reed J.C., Lommatzsch J., Takayama S., Wullner U., Loschmann P.A., Klockgether T., Weller M. Cooperative interception of neuronal apoptosis by Bcl-2 and Bag-1 expression: prevention of caspase activation and reduced production of reactive oxygen species. J. Neurochem. 69:1997;2075-2086.
36. Shaham S., Horvitz H.R. Developing Caenorhabditis elegans neurons may contain both cell-death protective and killer activities. Genes Dev. 10:1996;578-591.
37. Srinivasan A., Foster L.M., Testa M.P., Ord T., Keane R.W., Bredesen D.E., Kayalar C. Bcl-2 expression in neural cells blocks activation of ICE/Ced-3 family protease during apoptosis. J. Neurosci. 16:1996;5654-5660.
38. Tewari M., Quan L.T., O'Rourke K., Desnoyer S., Zeng Z., Beidler D.R., Poirier G.G., Salvesen G.S., Dixit V.M. Yama/cpp32β, a mammalian homolog of ced-3, is a CrmA-inhibitable protease that cleaves the death substrate Poly(ADP-Ribose) polymerase. Cell. 81:1995;801-809.
39. Van der Heiden M.G., Chandel N.S., Williamson E.K., Schumacker P.T., Thompson C.B. Bcl-xl regulates the membrane potential and the volume homeostasis of mitochondria. Cell. 91:1997;627-637.
40. Vekrellis K., MacCarthy M.J., Watson A., Whitfield J., Rubin L.L., Ham J. Bax promotes neuronal cell death and is downregulated during the development of the nervous system. Development. 124:1997;1239-1249.
41. Weil M., Jacobson M.D., Coles H.S. R., Davies T.J., Gardner R.L., Raff K.D., Raff M. Constitutive expression for the machinery of programmed cell death. J. Cell Biol. 133:1996;1053-1059.
42. White F.A., Keller-Peck C.R., Knudson C.M., Korsemeyer S.J., Snider W.D. Widespread elimination of naturally occurring neuronal death in Bax-deficient mice. J. Neurosci. 18:1998;1428-1439.
43. Xiang J., Chao D.T., Korsemeyer S.J. BAX- induced cell death may not require interleukin 1β-converting enzime-like proteases. Proc. natn. Acad. Sci. U.S.A. 93:1996;14559-14563.
44. Yasuhara N., Sahara S., Kamada S., Eguchi Y., Tsujimoto Y. Evidence against a functional site for Bcl-2 downstream of caspase cascade in preventing apoptosis. Oncogene. 15:1997;1921-1928.