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Vuoristo, M.1
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0035014931
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Randomized controlled trial of use by hypercholesterolaemic patients of avegetable oil sterol-enriched fat spread
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Reduction of serum cholesterol in postmenopausal women with previous myocardial infarction and cholesterol malasorption induced by dietary sitostanol ester margarine: Women and dietary sitostanol
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Gylling H, Radhakrishnan R, Miettinen TA: Reduction of serum cholesterol in postmenopausal women with previous myocardial infarction and cholesterol malasorption induced by dietary sitostanol ester margarine: Women and dietary sitostanol. Circulation (1997) 96:4226-4231.
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Incremental reduction of serum total cholesterol and low-density lipoprotein cholesterol with the addition of plant stanol ester-containing spread to statin therapy
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Stanol ester margarine alone and with simvastatin lower serum cholesterol in families with familial hypercholesterolemia caused by the FH-North Karelia mutation
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Vuorio AF, Gylling H, Turtola H, Kontula K, Ketonen P, Miettinen TA: Stanol ester margarine alone and with simvastatin lower serum cholesterol in families with familial hypercholesterolemia caused by the FH-North Karelia mutation. Arterioscler Thromb Vasc Biol (2000) 20:500-506.
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Gylling H, Miettinen TA: Effects of inhibiting cholesterol absorption and synthesis on cholesterol and lipoprotein metabolism in hypercholesterolemic non-insulin-dependent diabetic men. J Lipid Res (1996) 37:1776-1785. The metabolic and kinetic basis of stanol ester on serum cholesterol lowering is evaluated in detail.
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Miettinen TA, Strandberg TE, Gylling H: Noncholesterol sterols and cholesterol lowering by long-term simvastatin treatment in coronary patients: Relation to basal serum cholesterol. Artherioscler Thromb Vasc Biol (2000) 20:1340-1346. This study indicated for the first time that in coronary individuals with less favorable prognosis, levels of serum plant sterols and increased during long-term statin treatment.
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Serum plant sterol levels on and off satin treatment and stanol vs sterol ester consumption in a homozygous form of familial hypercholesterolemia
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Gylling H, Miettinen TA: Serum plant sterol levels on and off satin treatment and stanol vs sterol ester consumption in a homozygous form of familial hypercholesterolemia. XIV International Symposium on Drugs Affecting Lipids Metabolism, New York, NY, USA (2001):31.
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Inhibition of cholesterol synthesis and absorption in patients with acute myocardial infarction reduces serum cholesterol concentrations
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The effect of cholesterol absorption inhibition on low density lipoprotein cholesterol level
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Ezetimibe co-administered with simvastatin in 668 patients with primary hypercholesterolemia
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Davidson M, McQarry T, Bettis R, Melani L, Lipka L, BeBeaut A, Suresh R, Sun S, Veltri E, for the Ezetimibe Study Group: Ezetimibe co-administered with simvastatin in 668 patients with primary hypercholesterolemia. J Am Coll Cardiol (2002) 39 (Suppl 226A):1084-1090. This paper convincingly shows that the combination of ezetimibe with statins administered to large numbers of hypercholesterolemic patients further lowers LDL cholesterol by 12 to 14%, slightly lowers TG and increases HDL cholesterol by about 8%. In addition, a combination of ezetimibe with large doses of statins lowers LDL cholesterol by approximately 28% in homozygous FH patients.
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Ezetimibe co-administratered with atorvastatin in 628 patients with primary cholesterol hypercholesterolemia
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Ballantyne C, Houri J, Notarbartolo A, Melani L, Lipka L, LeBeaut A, Suresh R, Sun S, Veltri E, for the Ezetimibe Study Group: Ezetimibe co-administratered with atorvastatin in 628 patients with primary cholesterol hypercholesterolemia. J Am Coll Cardiol (2002) 39(Suppl227A):1084-1091. This paper convincingly shows that the combination of ezetimibe with statins administered to large numbers of hypercholesterolemic patients further lowers LDL cholesterol by 12 to 14%, slightly lowers TG and increases HDL cholesterol by about 8%. In addition, a combination of ezetimbe with large doses of statins lowers LDL cholesterol by approximately 28% in homozygous FH patients.
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Ezetimibe significantly reduces low density lipoprotein cholesterol in homozygous familial hypercholesterolemia
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Gagne C, Gaudet D, Bruckert E, Ponsonnet D, Lipka L, LeBeaut A, Suresh R, Abreu P, Veltri E, for the Ezetimibe Study Group: Ezetimibe significantly reduces low density lipoprotein cholesterol in homozygous familial hypercholesterolemia. J Am Coll Cardiol (2002) 39(Suppl 227A):1084-1092. This paper convicingly shows that the combination of ezetimibe with statins administered to large numbers of hypercholesterolemic patients further lowers LDL cholesterol by 12 to 14%, slightly lowers TG and increases HDL cholesterol by about 8%. In addition, a combination of ezetimibe with large doses of statins lowers LDL cholesterol by approximately 28% in homozygous FH patients.
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