The 2G single nucleotide polymorphism (SNP) in the MMP-1 promoter contributes to high levels of MMP-1 transcription in MCF-7/ADR breast cancer cells

Breast Cancer Research and Treatment

Volumn 82, Issue 2, 2003, Pages 75-82

  Tower, Grant B ^a   Coon, Charles I ^a   Brinckerhoff, Constance E ^a,b  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

^b 505 Vail Building ^*  (United States)

Author keywords

Collagen; ERK; Invasion metastasis; MAPK; Matrix metalloproteinase; Signal transduction

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE;

ALLELE; ARTICLE; BREAST CARCINOMA; CANCER CELL; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME SPECIFICITY; EXTRACELLULAR MATRIX; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; POLYOMA VIRUS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM;

BINDING SITES; BREAST NEOPLASMS; CELL LINE, TUMOR; COLLAGEN TYPE I; DOWN-REGULATION; ENZYME INHIBITORS; FLAVONOIDS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; IMIDAZOLES; MATRIX METALLOPROTEINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS (GENETICS); PYRIDINES; RNA, MESSENGER; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 0345257219     PISSN: 01676806     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:BREA.0000003948.14026.7c     Document Type: Article

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