Fluconazole attenuates lung injury and mortality in a rat peritonitis model

Intensive Care Medicine

Volumn 29, Issue 11, 2003, Pages 2043-2049

  Tariq, Mohammad ^a   Moutaery, Ahmed Al ^b   Arshaduddin, Mohammed ^a   Khan, Haseeb Ahmad ^a   Evans, David Price ^a   Jacobs, Sydney ^a  

^a The General Directorate of Armed Forces Health Services   (Saudi Arabia)

^b IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY   (Saudi Arabia)

Author keywords

Faecal peritonitis; Histology; Lungs; Myeloperoxidase; Neutrophil

Indexed keywords

FLUCONAZOLE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVITY; COMPARATIVE STUDY; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; LUNG ALVEOLUS; LUNG EDEMA; LUNG INJURY; MALE; MORTALITY; NEUTROPHIL; NONHUMAN; OXIDATIVE STRESS; PATHOLOGICAL ANATOMY; PERITONITIS; RAT; RAT STRAIN; SURVIVAL RATE; SURVIVAL TIME;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ASCITIC FLUID; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; DRUG EVALUATION, PRECLINICAL; FLUCONAZOLE; INFLAMMATION; INJECTIONS, INTRAPERITONEAL; INTESTINAL PERFORATION; LUNG; MALE; NEUTROPHIL ACTIVATION; OXIDATIVE STRESS; PERITONITIS; PEROXIDASE; RATS; RATS, WISTAR; RESPIRATORY DISTRESS SYNDROME, ADULT; SUPEROXIDE DISMUTASE; SURVIVAL RATE; TIME FACTORS;

EID: 0345257062     PISSN: 03424642     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00134-003-1960-3     Document Type: Article

References (37)

1. Schein M (1991) Planned reoperations and open management in critical intra abdominal infections: prospective experience in 52 cases. World J Surgery 15:537-545
2. Jacobs S, Sobki S, Morais C, Tariq M (2000) Effect of pentaglobin and piperacillin on survival in a rat model of faecal peritonitis: importance of intervention timings. Acta Anaesth Scand 44:88-95
3. Carey PD, Jenkins JK, Byrne K, Schneider AM, Walsh CJ, Fowler AA, Sugerman HJ (1992) Neutrophil short-lived oxidant production: enhancement following onset of sepsis-induced lung injury. Circ Shock 36:256-264
4. Sheridan BC, Mcintyre RC, Agrafojo JR, Meldrum DR, Meng X, Fullerton DA (1996) Neutrophil depletion attenuates endotoxin induced dysfunction of CGMP mediated pulmonary vasorelaxation. Am J Physiol 271:L820-L828
5. Zeiher BG, Matsuoka S, Kawabata K, Repine JE (2002) Neutrophil elastase and acute lung injury: prospects for silvestat and other neutrophil elastase inhibitors as therapeutics. Crit Care Med 30[Suppl]:S281-S287
6. Noronha-Blob N, Lowe VC, Otterbein L, Steranka L, Burch RM (1993) NPC 15669 reduces mortality associated with sepsis in rats. J Pharmacol Exp Ther 267:664-669
7. Greenman RL, Schein RMH, Martin MA, Wenzel RR, Mcintyre NR, Emmanuel G, Chmel H, Kohler RB, McCarthy M, Plouffe J, Jane A, Russell JA (1991) Controlled clinical trial of E5 murine monoclonal Igm antibody to endotoxin in the treatment of gram negative sepsis. JAMA 266:1097-1102
8. Rowan Kelly B, Ferrante A, Thong YH (1984) Modification of polymorphonuclear leukocyte function by imidazoles. Int J Immunopharmacol 40:186-192
9. Vudhakul V, McCormak JG, Seew WK, Thong YH (1989) Effects of the newer antifungal agents (bifonazole ICI 195739 and amorolfin) on in vitro phagocytic, lymphocytic and natural killer cell responses. Int J Immunopharmacol 11:817-828
10. Drummond DC, Wong CW, Whitman LM, McCormack JG (1995) The effects of amphotericin B, fluconazole and miconazole on neutrophil and lymphocyte function in a guinea pig model. J Antimicro Chemo 36:375-384
11. Slotman GJ, Burchard KW, D'Arezzo, Gann DS (1988) Ketoconazole prevents acute respiratory failure in critically ill surgical patients. J Trauma 28:648-654
12. ARDS Network Authors for the ARDS Network (2000) Ketoconazole for early treatment of acute lung injury and acute respiratory distress syndrome. A randomized controlled trial. JAMA 283:1995-2002
13. Buijk SLCE, Gyssens IC, Mouton JW, Verbrugh HA, Touw TJ, Bruining HA (2001) Pharmacokinetics of sequential intravenous and enterai fluconazole in critically ill surgical patients with invasive mycoses and compromised gastrointestinal function. Int Care Med 27:115-121
14. Zervos EE, Boss SS, Robinson MC, Rosemurgy AS (1996) Fluconazole increases bactericidal activity of neutrophils through non-cytokine mediated pathway. J Trauma Injury Infect Crit Care 41:465-470
15. Pitzurra L, Fringuelli R, Perito S, Schafeella F, Barluzzi R, Bistoni F, Vecchiarelli A (1999) A new azole derivative of 1,4 benzothiazine increases the antifungal mechanisms of natural effector cells. Antimicrob Agents Chemotherap 43:2170-2175
16. Salartash K, Galluci J, Quinn J, Catalono E, Slotman G (1996) The cardiopulmonary, eicosanoid and microanatomical effects of fluconazole during graded bacteraemia. Shock 6:206-212
17. Vela AR, Littleton JC, O'Leary JP (1999) The effects of minidose heparin and low molecular weight heparin on peritonitis in the rat. Am J Surg 67:473-477
18. 2 or helium) on intraperitoneal adhesion formation in a rat peritonitis model. Surg Endosc 15:380-386
19. Goldblum SE, Wu KM, Jay M (1985) Lung myeloperoxidase as a measure of pulmonary leukostasis in rabbits. J Appl Physiol 59:1978-1985
20. Liluis E, Waris M (1984) A very sensitive and rapid chemiluminescence method for the measurement of phagocytosis. Analytical applications of bioluminescence and chemiluminescence. Academic, New York, pp 401-404
21. Beauchamp E, Fridovich I (1971) Superoxide dismutase: improved assays and an assay applicable to acrylamide gels. Anal Biochem 44:276-287
22. Sawyer RG, Adam RB, Rosenlof LK, May AK, Pruett TL (1995) Effectiveness of fluconazole in murine candida albicans and bacterial C. Albicans peritonitis and abscess formation. J Med Vet Mycol 33:131-136
23. Rosemurgy AS, Sweeney JF, Albrink MH (1993) Implications of candida antigen titers in injured adults. Contemp Surg 42:327
24. Horn R, Wong B, Kiehn TE, Armstrong D (1985) Fungemia in a cancer hospital: changing frequency, earlier onset and results of therapy. Rev Infect Dis 7:646
25. Matute-Bello G, Frevert CW, Kajikawa O, Skerret SJ, Goodman RB, Park DR, Martin TR (2001) Septic shock and acute lung injury in rabbits with peritonitis. Failure of the neutrophil response to localized infection. Am J Respir Crit Care Med 163:234-243
26. Heemken RL, Gandawidaja L, Hau T (1997) Peritonitis: pathophysiology and local defense mechanisms. Hepatogastroenterology 44:927-936
27. Stephens K, Ishika A, Wu Z, Larrick J, Raffin T (1988) Granulocyte depletion prevents tumor necrosis factor mediated acute lung injury in guinea pigs. Am Rev Respir Dis 138:1300
28. Fantone JC, Ward PA (1985) Polymorphonuclear leukocyte mediated cell and tissue injury: oxygen metabolites and their relations to human disease. Human Pathol 16:973-978
29. Basadre JO, Sugi K, Traber DL, Niehaus GD, Herndon DN (1988) The effect of leukocyte depletion on smoke inhalation injury in sheep. Surgery 104:208-215
30. Burch RM, Weitzberg M, Noronha-Blob L, Lowe VC, Bator JM, Perumattam J, Sullivan J (1992b) Leumelins-novel leukocyte recruitment inhibitors with activity in animal models of dermatitis, sepsis and inflammatory bowel diseases. Drugs News Perspect 5:331-337
31. Suzuki M, Nakamura M, Mori M, Miura S, Tsuchija M, Ishii H (1995) Lansoprazole inhibits oxygen derived free radicals production from neutrophils activated by Helicobacter pylori. J Clin Gastroenterol 20[Suppl 2]:S93-S96
32. Wandall JH (1992) Effects of omeprazole on neutrophil chemotaxis, superoxide production, degranulation and translocation of cytochrome b. Gut 33:617-621
33. Welty Wolf KE, Carraway MS, Huang YT, Simonson SG, Kantrow SP, Kishimoto TK, Piantodosi CA (2001) Antibody to intercellular adhesion molecule 1 (CD54) decreases survival and not lung injury in baboons with sepsis. Am J Respir Crit Care Med 163:665-673
34. Spark JI, Scott DJA (2001) Role of the neutrophil in the development of systemic inflammatory response syndrome and sepsis following abdominal aortic surgery. Br J Surg 88:1583-1589
35. Pesanti EL, Nugent KM (1985) Modulation of pulmonary clearance of bacteria by antioxidants. Infect Immun 48:57-61
36. Goode HF, Webster NR (1992) Free radicals and trace element metabolism in sepsis and injury. Br J Intensive Care 2:312-322
37. Simons RK, Maier RV, Lennard ES (1987) Neutrophil function in a rat model of endotoxin induced lung injury. Arch Surg 122:197-203