Pharmacokinetics of sequential intravenous and enteral fluconazole in critically ill surgical patients with invasive mycoses and compromised gastro-intestinal function

Intensive Care Medicine

Volumn 27, Issue 1, 2001, Pages 115-121

  Buijk, S L C E ^a,c   Gyssens, I C ^a   Mouton, J W ^a   Verbrugh, H A ^a   Touw, D J ^b   Bruining, H A ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^c Reinier de Graaf Gasthuis ^*  (Netherlands)

Author keywords

Compromised gastro intestinal function; Critically ill; Deep mycoses; Fluconazole; Pharmacokinetics

Indexed keywords

ANTIFUNGAL AGENT; FLUCONAZOLE;

ADULT; AREA UNDER THE CURVE; ARTICLE; CLINICAL ARTICLE; CRITICAL ILLNESS; DRUG HALF LIFE; DRUG METABOLISM; ENTERIC FEEDING; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INFUSION PUMP; INTENSIVE CARE UNIT; MALE; MYCOSIS; SURGICAL PATIENT;

ANTIFUNGAL AGENTS; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; DIGESTIVE SYSTEM SURGICAL PROCEDURES; ENTERAL NUTRITION; FEMALE; FLUCONAZOLE; FUNGEMIA; HALF-LIFE; HUMANS; INFUSIONS, INTRAVENOUS; INTENSIVE CARE UNITS; MALE; MEDIASTINITIS; MIDDLE AGED; MYCOSES; PERITONITIS; POSTOPERATIVE COMPLICATIONS; STATISTICS, NONPARAMETRIC;

EID: 0035090910     PISSN: 03424642     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001340000771     Document Type: Article

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