p53 expression in locally advanced pharyngeal squamous cell carcinoma

Archives of Otolaryngology - Head and Neck Surgery

Volumn 125, Issue 12, 1999, Pages 1356-1359

  Lassaletta, Luis ^a   Brandáriz, Jose A ^b   Benito, Amparo ^b   De La Cruz, Javier ^b   Gómez, Carlos ^b   Ballestín, Claudio ^b   Hitt, Ricardo ^b   Colomer, Ramon ^b   Álvarez Vicent, Juan J ^b  

^a HOSPITAL UNIVERSITARIO LA PAZ   (Spain)

^b HOSPITAL UNIVERSITARIO 12 DE OCTUBRE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; FLUOROURACIL; PROTEIN P53;

ADVANCED CANCER; ARTICLE; CANCER CONTROL; CANCER SURVIVAL; FEMALE; GENE MUTATION; HUMAN; IMMUNOHISTOCHEMISTRY; MALE; PHARYNX CARCINOMA; PROGNOSIS; SQUAMOUS CELL CARCINOMA; SURVIVAL RATE; TUMOR SUPPRESSOR GENE;

EID: 0345201658     PISSN: 08864470     EISSN: None     Source Type: Journal    
DOI: 10.1001/archotol.125.12.1356     Document Type: Article

References (24)

1. Vokes EE, Athanasiadis I. Chemotherapy of squamous cell carcinoma of head and neck: the future is now. Ann Oncol. 1996;7:15-29.
2. Greenblatt MS, Bennett WP, Hollstein M, Harris CC. Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res. 1994;54:4855-4878.
3. Pavelic ZP, Gluckman JL, Gapany M, et al. Improved immunohistochemical detection of p53 protein in paraffin-embedded tissues reveals elevated levels in most head and neck and lung carcinomas: correlation with clinicopathological parameters. Anticancer Res. 1992;12:1389-1394.
4. Watling DL, Gown AM, Coultera MD. Overexpression of p53 in head and neck cancer. Head Neck. 1992;14:437-444.
5. Frank JL, Bur ME, Garb JL, et al. p53 Tumor suppressor oncogene expression in squamous cell carcinoma of the hypopharynx. Cancer. 1994;73:181-186.
6. Vogelstein B, Kinzler KW. p53 Function and dysfunction. Cell. 1992;70:523-526.
7. Lowe SW, Ruley HE, Jacks T, Housman DE. p53-Dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell. 1993;74:957-967.
8. Harris CC, Hollstein M. Clinical implications of the p53 tumor-suppressor gene [see comments]. N Engl J Med. 1993;329:1318-1327.
9. Norusis MJ. SPSSX: Statistical Package for the Social Sciences Plus. New York, NY: McGraw-Hill Book Co; 1983.
10. Armitage P, Berry G. Statistical Methods in Medical Research. Oxford, England: Blackwell Publishers; 1987.
11. Hosmer DW, Lemeshow S. Applied Logistic Regression. New York, NY: John Wiley & Sons Inc; 1989.
12. Kaplan EL, Meir P. Non-parametric estimation for incomplete observations. J Am Stat Assoc. 1958;53:457-481.
13. Lee ET. Statistical Methods for Survival Data Analysis. New York, NY: John Wiley & Sons Inc; 1992.
14. Mantel N, Haenszel W. Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst. 1959;22:719-748.
15. Cox DR. Regression models and life tables, J R Stat Soc Ser B. 1972;34:187-220.
16. Caminero MJ, Nunez F, Suarez C, Ablanedo P, Riera JR, Dominguez F. Detection of p53 protein in oropharyngeal carcinoma: prognostic implications. Arch Otolaryngol Head Neck Surg. 1996;122:769-772.
17. Spafford MF, Koeppe J, Pan Z, Archer PG, Meyers AD, Franklin WA. Correlation of tumor markers p53, bcl-2, CD34, CD44H, CD44v6, and Ki-67 with survival and metastasis in laryngeal squamous cell carcinoma. Arch Otolaryngol Head Neck Surg. 1996;122:627-632.
18. Lowe SW, Bodis S, McClatchey A, et al. p53 Status and the efficacy of cancer therapy in vivo. Science. 1994;266:807-810.
19. Dunphy CH, Dunphy FR, Boyd JH, et al. Expression of p53 protein in advanced head and neck squamous cell carcinoma before and after chemotherapy. Arch Otolaryngol Head Neck Surg. 1997;123:1223-1225.
20. Lavieille JP, Brambilla E, Riva-Lavieille C, Reyt E, Charachon R, Brambilla C. Immunohistochemical detection of p53 protein in preneoplastic lesions and squamous cell carcinoma of the head and neck. Acta Otolaryngol (Stockh). 1995; 115:334-339.
21. Bradford CR, Zhu S, Wolf GT, et al. Overexpression of p53 predicts organ preservation using induction chemotherapy and radiation in patients with advanced laryngeal cancer. Otolaryngol Head Neck Surg. 1995;113:408-412.
22. Riva C, Lavieille JP, Reyt E, Brambilla E, Lunardi J, Brambilla C. Differential c-myc, c-jun, c-raf and p53 expression in squamous cell carcinoma of the head and neck: implication in drug and radioresistance. Eur J Cancer B Oral Oncol. 1995;31B:384-391.
23. Perego P, Giarola M, Righetti SC, et al. Association between cisplatin resistance and mutation of p53 gene and reduced bax expression in ovarian carcinoma cell systems. Cancer Res. 1996;56:556-562.
24. Melhem MF, Law JC, el Ashmawy L, et al. Assessment of sensitivity and specificity of immunohistochemical staining of p53 in lung and head and neck cancers. Am J Pathol. 1995;146:1170-1177.