Detection of p53 protein in oropharyngeal carcinoma: Prognostic implications

Archives of Otolaryngology - Head and Neck Surgery

Volumn 122, Issue 7, 1996, Pages 769-772

  Caminero, María J ^a,b   Núñez, Faustino ^a   Suárez, Carlos ^a   Ablanedo, Pilar ^a   Riera, Jose R ^a   Dominguez, Francisco ^a  

^a HOSPITAL VALLE DEL NALÓN   (Spain)

^b NONE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN G; MONOCLONAL ANTIBODY; PROTEIN P53;

ADULT; AGED; ARTICLE; CANCER GRADING; CANCER RECURRENCE; CANCER STAGING; CELL NUCLEUS; COHORT ANALYSIS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; OROPHARYNX CARCINOMA; PROGNOSIS; SQUAMOUS CELL CARCINOMA; SURVIVAL RATE;

EID: 0029945329     PISSN: 08864470     EISSN: None     Source Type: Journal    
DOI: 10.1001/archotol.1996.01890190065015     Document Type: Article

References (11)

1. Davis RK. Prognostic variables in head and neck cancer tumor site, stage, nodal status, differentiation, and immune status. Otolaryngol Clin North Am. 1985; 18:411-419.
2. Gavilán J, Gavilán C, Mañós-Pujol M, Herranz J. Discriminant analysis in predicting survival of patients with cancer of the larynx or hypopharynx. Clin Otolaryngol. 1987;12:331-335.
3. Snow GB. Cancer of the head and neck region. In: Veronesi V, ed. Surgical Oncology. New York, NY: Springer-Verlag; 1989:476-494.
4. Bourhis J. Oncogenes and tumor-suppressor genes in human cancers: clinical implications. Br J Radiol. 1992;24:215-219.
5. Brachman D, Graves D, Vokes E, et al. Occurrence of p53-gene deletions and human-papilloma-virus infection in human head-and-neck cancer. Cancer Res. 1992;52:4832-4836.
6. Field JK, Pavelic ZP, Spandidos DA, Stambrook PJ, Jones Gluckman JL. The role of the p53 tumor suppressor gene in squamous cell carcinoma of the head and neck. Arch Otolaryngol Head Neck Surg. 1993;119:1118-1122.
7. Bennet W, Hollstein M, He A, et al. Archival analysis of p53 genetic and protein alteration in Chinese oesophageal cancer. Oncogene. 1991;6:1779-1784.
8. Greenblatt MS, Bennett WP, Hollstein M, Harris CC. Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res. 1994;54:4855-4878.
9. Bourhis J, Bosq J, Wilson GD, et al. Correlation between p53 gene expression and tumor-cell proliferation in oropharyngeal cancer. Int J Cancer. 1994;57: 458-462
10. Field JK, Malliri A, Butt SA, et al. p53 Over-expression in end-stage squamous cell carcinomas of the head and neck: correlates with a very poor clinical outcome. Int J Oncol. 1993;3:431-435.
11. Brennan JA, Mao L, Hruban RH, et al. Molecular assessment of histopathological staging in squamous-cell carcinoma of the head and neck. N Engl J Med. 1995;332:429-435.