Relevance of L-selectin shedding for leukocyte rolling in vivo

Journal of Experimental Medicine

Volumn 189, Issue 6, 1999, Pages 939-947

  Hafezi Moghadam, Ali ^a   Klaus, Ley ^a  

^a University of Virginia   (United States)

Author keywords

Inflammation; Mouse; Protease inhibitor; Trafficking velocity

Indexed keywords

ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; L SELECTIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ENDOTHELIUM; LEUKOCYTE MIGRATION; LEUKOCYTE MOTILITY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION;

ANIMALS; CELL MOVEMENT; L-SELECTIN; LEUKOCYTES; MALE; MICE; MICE, INBRED C57BL; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0345196534     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.189.6.939     Document Type: Article

References (42)

1. Ley, K., and T. Tedder. 1995. Leukocyte interactions with vascular endothelium. New insights into selectin-mediated attachment and rolling. J. Immunol. 155:525-528.
2. Springer, T. 1995. Traffic signals on endothelium for lymphocyte recirculation and leukocyte emigration. Annu. Rev. Physiol. 57:827-872.
3. Dore, M., R. Korthuis, D. Granger, M. Entman, and C. Smith. 1993. P-selectin mediates spontaneous leukocyte rolling in vivo. Blood. 82:1308-1316.
4. Kansas, G. 1996. Selectins and their ligands: current concepts and controversies. Blood. 88:3259-3287.
5. Ley, K., P. Gaehtgens, C. Fennie, M. Singer, L. Lasky, and S. Rosen. 1991. Lectin-like cell adhesion molecule 1 mediates leukocyte rolling in mesenteric venules in vivo. Blood. 77: 2553-2555.
6. Ley, K., D. Bullard, M. Arbones, R. Bosse, D. Vestweber, T. Tedder, and A. Beaudet. 1995. Sequential contribution of L- and P-selectin to leukocyte rolling in vivo. J. Exp. Med. 181:669-675.
7. Hammer, D., and S. Apte. 1992. Simulation of cell rolling and adhesion on surfaces in shear flow: general results and analysis of selectin-mediated neutrophil adhesion. Biophys. J. 63:35-57.
8. Tözeren, A., and K. Ley. 1992. How do selectins mediate leukocyte rolling in venules? Biophys. J. 63:700-709.
9. Alon, R., S. Chen, K. Puri, E. Finger, and T. Springer. 1997. The kinetics of L-selectin tethers and the mechanics of selectin-mediated rolling. J. Cell Biol. 138:1169-1180.
10. Puri, K., S. Chen, and T. Springer. 1998. Modifying the mechanical property and shear threshold of L-selectin adhesion independently of equilibrium properties. Nature. 392:930-933.
11. Jutila, M., L. Rott, E. Berg, and E. Butcher. 1989. Function and regulation of the neutrophil MEL-14 antigen in vivo: comparison with LFA-1 and MAC-1. J. Immunol. 143:3318-3324.
12. Kishimoto, T., M. Jutila, E. Berg, and E. Butcher. 1989. Neutrophil Mac-1 and MEL-14 adhesion proteins inversely regulated by chemotactic factors. Science. 245:1238-1241.
13. van Eeden, S., R. Miyagashima, L. Haley, and J. Hogg. 1997. A possible role for L-selectin in the release of polymorphonuclear leukocytes from bone marrow. Am. J. Physiol. 272: H1717-H1724.
14. Chen, A., P. Engel, and T.F. Tedder. 1995. Structural requirements regulate endoproteolytic release of the L-selectin (CD62L) adhesion receptor from the cell surface of leukocytes. J. Exp. Med. 182:519-530.
15. Kahn, J., R. Ingraham, F. Shirley, G. Migaki, and T. Kishimoto. 1994. Membrane proximal cleavage of L-selectin: identification of the cleavage site and a 6-kD transmembrane peptide fragment of L-selectin. J. Cell Biol. 125:461-470.
16. Schleiffenbaum, B., O. Spertini, and T. Tedder. 1992. Soluble L-selectin is present in human plasma at high levels and retains functional activity. J. Cell Biol. 119:229-238.
17. Bazil, V., and J. Strominger. 1994. Metalloprotease and serine protease are involved in cleavage of CD43, CD44, and CD16 from stimulated human granulocytes. Induction of cleavage of L-selectin via CD16. J. Immunol. 152:1314-1322.
18. Kishimoto, T., J. Kahn, G. Migaki, E. Mainolfi, F. Shirley, R. Ingraham, and R. Rothlein. 1995. Regulation of L-selectin expression by membrane proximal proteolysis. Agents Actions Suppl. 47:121-134.
19. Shipp, M., G. Stefano, S. Switzer, J. Griffin, and E. Reinherz. 1991. CD10 (CALLA)/neutral endopeptidase 24.11 modulates inflammatory peptide-induced changes in neutrophil morphology, migration, and adhesion proteins and is itself regulated by neutrophil activation. Blood. 78:1834-1841.
20. Preece, G., G. Murphy, and A. Ager. 1996. Metalloproteinase-mediated regulation of L-selectin levels on leucocytes. J. Biol. Chem. 271:11634-11640.
21. Feehan, C., K. Darlak, J. Kahn, B. Walcheck, A. Spatola, and T. Kishimoto. 1996. Shedding of the lymphocyte L-selectin adhesion molecule is inhibited by a hydroxamic acid-based protease inhibitor. Identification with an L-selectin-alkaline phosphatase reporter. J. Biol. Chem. 271:7019-7024.
22. Bennett, T., E. Lynam, L. Sklar, and S. Rogelj. 1996. Hydroxamate-based metalloprotease inhibitor blocks shedding of L-selectin adhesion molecule from leukocytes: functional consequences for neutrophil aggregation. J. Immunol. 156: 3093-3097.
23. Walcheck, B., J. Kahn, J. Fisher, B. Wang, R. Fisk, D. Payan, C. Feehan, R. Betageri, K. Darlak, A. Spatola, and T. Kishimoto. 1996. Neutrophil rolling altered by inhibition of L-selectin shedding in vitro. Nature. 380:720-723.
24. Allport, J., H. Ding, A. Ager, D. Steeber, T. Tedder, and F. Luscinskas. 1997. L-selectin shedding does not regulate human neutrophil attachment, rolling, or transmigration across human vascular endothelium in vitro. J. Immunol. 158:4365-4372.
25. Bosse, R., and D. Vestweber. 1994. Only simultaneous blocking of the L- and P-selectin completely inhibits neutrophil migration into mouse peritoneum. Eur. J. Immunol. 24: 3019-3024.
26. Kunkel, E., U. Jung, D. Bullard, K. Norman, B. Wolitzky, D. Vestweber, A. Beaudet, and K. Ley. 1996. Absence of trauma-induced leukocyte rolling in mice deficient in both P-selectin and intercellular adhesion molecule 1. J. Exp. Med. 183:57-65.
27. Norton, C., J. Rumberger, D. Burns, and B. Wolitzky. 1993. Characterization of murine E-selectin expression in vitro using novel anti-mouse E-selectin monoclonal antibodies. Biochem. Biophys. Res. Commun. 195:250-258.
28. Arbones, M., D. Ord, K. Ley, H. Ratech, C. Maynard-Curry, G. Otten, D. Capon, and T. Tedder. 1994. Lymphocyte homing and leukocyte rolling and migration are impaired in L-selectin-deficient mice. Immunity. 1:247-260.
29. Bullard, D., E. Kunkel, H. Kubo, M. Hicks, I. Lorenzo, N. Doyle, C. Doerschuk, K. Ley, and A. Beaudet. 1996. Infectious susceptibility and severe deficiency of leukocyte rolling and recruitment in E-selectin and P-selectin double mutant mice. J. Exp. Med. 183:2329-2336.
30. Jung, U., C. Ramos, D. Bullard, and K. Ley. 1998. Gene-targeted mice reveal importance of L-selectin-dependent rolling for neutrophil adhesion. Am. J. Physiol. 43:H1785-H1791.
31. Baez, S. 1973. An open cremaster muscle preparation for the study of blood vessels by in vivo microscopy. Microvasc. Res. 5:384-394.
32. Pries, A. 1988. A versatile video image analysis system for microcirculatory research. Int. J. Microcirc. Clin. Exp. 7:327-345.
33. Lipowsky, H., and B. Zweifach. 1978. Application of the "two-slit" photometric technique to the measurement of microvascular volumetric flow rates. Microvasc. Res. 15:93-101.
34. Reneman, R., B. Woldhuis, M. oude Egbrink, D. Slaaf, and G. Tangelder. 1992. Concentration and velocity profiles of blood cells in the microcirculation. In Advances in Cardiovascular Engineering. N. Hwang, V. Turitto, and M. Yen, editors. Plenum Publishing Corp., New York. 25-40.
35. Ley, K., and P. Gaehtgens. 1991. Endothelial, not hemodynamic, differences are responsible for preferential leukocyte rolling in rat mesenteric venules. Circ. Res. 69:1034-1041.
36. Jung, U., and K. Ley. 1997. Regulation of E-selectin, P-selectin, and intercellular adhesion molecule 1 expression in mouse cremaster muscle vasculature. Microcirculation. 4:311-319.
37. Kunkel, E., and K. Ley. 1996. Distinct phenotype of E-selectin-deficient mice. E-selectin is required for slow leukocyte rolling in vivo. Circ. Res. 79:1196-1204.
38. Kaplanski, G., C. Farnarier, O. Tissot, A. Pierres, A.M. Benoliel, M.C. Alessi, S. Kaplanski, and P. Bongrand. 1993. Granulocyte-endothelium initial adhesion. Analysis of transient binding events mediated by E-selectin in a laminar shear flow. Biophys. J. 64:1922-1933.
39. Palecanda, A., B. Walcheck, D. Bishop, and M. Jutila. 1992. Rapid activation-independent shedding of leukocyte L-selectin induced by crosslinking of the surface antigen. Eur. J. Immunol. 22:1279-1286.
40. Lalor, P., J. Clements, R. Pigott, M. Humphries, J. Spragg, and G. Nash. 1997. Association between receptor density, cellular activation, and transformation of adhesive behavior of flowing lymphocytes binding to VCAM-1. Eur. J. Immunol. 27:1422-1426.
41. Lawrence, M., and T. Springer. 1993. Neutrophils roll on E-selectin. J. Immunol. 151:6338-6346.
42. Jung, U., K. Norman, K. Scharffetter-Kochanek, A. Beaudet, and K. Ley. 1998. Transit time of leukocytes rolling through venules controls cytokine-induced inflammatory cell recruitment in vivo. J. Clin. Invest. 102:1526-1533.