Differential actions of diazepam and zolpidem in basolateral and central amygdala nuclei

Neuropharmacology

Volumn 46, Issue 1, 2004, Pages 1-9

  Kang Park, M H ^a   Wilson, W A ^a,b   Moore, S D ^a,b  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b DURHAM VA MEDICAL CENTER   (United States)

Author keywords

Amygdala; Anxiety; Diazepam; GABAA receptors; Zolpidem

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; DIAZEPAM; ZOLPIDEM;

AMYGDALOID NUCLEUS; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG POTENCY; HISTOCHEMISTRY; INHIBITORY POSTSYNAPTIC POTENTIAL; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; RECORDING; TRANQUILIZING ACTIVITY;

EID: 0345118977     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(03)00340-X     Document Type: Article

References (36)

1. Cohen A.S., Lin D.D., Coulter D.A. Protracted postnatal development of inhibitory synaptic transmission in rat hippocampal area CA1 neurons. J. Neurophysiol. 84:2000;2465-2476.
2. Crestani F., Martin J.R., Möhler H., Rudolph U. Mechanism of action of the hypnotic zolpidem in vivo. Br. J. Pharmacol. 131:2000;1251-1254.
3. Delaney A.J., Sah P. GABA receptors inhibited by benzodiazepines mediate fast inhibitory transmission in the central amygdala. J. Neurosci. 19:1999;9698-9704.
4. Delaney A.J., Sah P. Pathway-specific targeting of GABA(A) receptor subtypes to somatic and dendritic synapses in the central amygdala. J. Neurophysiol. 86:2001;717-723.
5. Doble A. New insights into the mechanism of action of hypnotics. J. Psychopharmacol. 13:1999;S11-S20.
6. File S. The amygdala: anxiety and benzodiazepines. Aggleton J.P. The Amygdala: a Functional Analysis. 2000;195-212 Oxford University Press, Oxford.
7. A-receptor heterogeneity in the adult rat brain: differential regional and cellular distribution of seven major subunits. J. Comp. Neurol. 359:1995;154-194.
8. Gonzalez L.E., Andrews N., File S.E. 5-HT1A and benzodiazepine receptors in the basolateral amygdala modulate anxiety in the social interaction test, but not in the elevated plus-maze. Brain Res. 732:1996;145-153.
9. Graeff F.G., Silveira M.C., Nogueira R.L., Audi E.A., Oliveira R.M. Role of the amygdala and periaqueductal gray in anxiety and panic. Behav. Brain Res. 58:1993;123-131.
10. Griebel G., Perrault G., Sanger D.J. Limited anxiolytic-like effects of non-benzodiazepine hypnotics in rodents. J. Psychopharmacol. 12:1998;356-365.
11. A receptor occupancy. Eur. J. Neurosci. 12:2000;810-818.
12. Harris J.A., Westbrook R.F. Effects of benzodiazepine microinjection into the amygdala or periaqueductal gray on the expression of conditioned fear and hypoalgesia in rats. Behav. Neurosci. 109:1995;295-304.
13. Helmstetter F.J. Stress-induced hypoalgesia and defensive freezing are attenuated by application of diazepam to the amygdala. Pharmacol. Biochem. Behav. 44:1993;433-438.
14. Higashima M., Kinoshita H., Yamaguchi N., Koshino Y. Differences in enhancing effects of zolpidem and benzodiazepine drugs on recurrent inhibition in rat hippocampal slices. Psychopharmacology. 131:1997;394-398.
15. Kang-Park M., Wilson W., Moore S. Differential actions of diazepam and zolpidem in basolateral and central amygdala. Soc. Neurosci. Abst. 32:2002;39.
16. Kaufmann W.A., Humpel C., Alheid G.F., Marksteiner J. Compartmentation of alpha 1 and alpha 2 GABA(A) receptor subunits within rat extended amygdala: implications for benzodiazepine action. Brain Res. 964:2003;91-99.
17. Kralic J.E., O'Buckley T.K., Khisti R.T., Hodge C.W., Homanics G.E., Morrow A.L. GABA(A) receptor alpha-1 subunit deletion alters receptor subtype assembly, pharmacological and behavioral responses to benzodiazepines and zolpidem. Neuropharmacology. 43:2002;685-694.
18. Löw K., Crestani F., Keist R., Benke D., Brunig I., Benson J.A., Fritschy J.M., Rulicke T., Bluethmann H., Möhler H., Rudolph U. Molecular and neuronal substrate for the selective attenuation of anxiety. Science. 290:2000;131-134.
19. McKernan R.M., Rosahl T.W., Reynolds D.S., Sur C., Wafford K.A., Atack J.R., Farrar S., Myers J., Cook G., Ferris P., Garrett L., Bristow L., Marshall G., Macaulay A., Brown N., Howell O., Moore K.W., Carling R.W., Street L.J., Castro J.L., Ragan C.I., Dawson G.R., Whiting P.J. Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABA(A) receptor alpha1 subtype. Nat. Neurosci. 3:2000;587-592.
20. McNaughton N., Gray J.A. Anxiolytic action on the behavioural inhibition system implies multiple types of arousal contribute to anxiety. J. Affect. Disord. 61:2000;161-176.
21. A receptors. Brain Res. Rev. 29:1999;196-217.
22. Menard J., Treit D. Effects of centrally administered anxiolytic compounds in animal models of anxiety. Neurosci. Biobehav. Rev. 23:1999;591-613.
23. Nagy J., Zambo K., Decsi L. Anti-anxiety action of diazepam after intra-amygdaloid application in the rat. Neuropharmacology. 18:1979;573-576.
24. A receptor complex ligands in two models of anxiety. J. Neural Transm. 104:1997;733-746.
25. Okada M., Onodera K., Van Renterghem C., Sieghart W., Takahashi T. Functional correlation of GABA(A) receptor alpha subunits expression with the properties of IPSCs in the developing thalamus. J. Neurosci. 20:2000;2202-2208.
26. Pesold C., Treit D. The septum and amygdala differentially mediate the anxiolytic effects of benzodiazepines. Brain Res. 638:1994;295-301.
27. Pesold C., Treit D. The central and basolateral amygdala differentially mediate the anxiolytic effects of benzodiazepines. Brain Res. 671:1995;213-221.
28. Petersen E.N., Braestrup C., Scheel-Kruger J. Evidence that the anticonflict effect of midazolam in amygdala is mediated by the specific benzodiazepine receptors. Neurosci. Lett. 53:1985;285-288.
29. Pirker S., Schwarzer C., Wieselthaler A., Sieghart W., Sperk G. GABA(A) receptors: immunocytochemical distribution of 13 subunits in the adult rat brain. Neuroscience. 101:2000;815-850.
30. A receptor subunit for benzodiazepine pharmacology. Nature. 338:1989;582-585.
31. Rudolph U., Crestani F., Benke D., Brunig I., Benson J.A., Fritschy J.M., Martin J.R., Bluethmann H., Möhler H. Benzodiazepine actions mediated by specific gamma-aminobutyric acid(A) receptor subtypes. Nature. 401:1999;796-800.
32. Rudolph U., Crestani F., Möhler H. GABA(A) receptor subtypes: dissecting their pharmacological functions. Trends Pharmacol. Sci. 22:2001;188-194.
33. Rush C.R. Behavioral pharmacology of zolpidem relative to benzodiazepines: a review. Pharmacol. Biochem. Behav. 61:1998;253-269.
34. Schmitt U., Hiemke C. Combination of open field and elevated plus-maze: a suitable test battery to assess strain as well as treatment differences in rat behavior. Prog. Neuropsychopharmacol. Biol. Psychiatry. 22:1998;1197-1215.
35. Treit D., Pesold C., Rotzinger S. Noninteractive effects of diazepam and amygdaloid lesions in two animal models of anxiety. Behav. Neurosci. 107:1993;1099-1105.
36. Zangrossi H. Jr., Viana M.B., Graeff F.G. Anxiolytic effect of intra-amygdala injection of midazolam and 8-hydroxy-2-(di-n-propylamino) tetralin in the elevated T-maze. Eur. J. Pharmacol. 369:1999;267-270.