Minimal leptin elimination into ultrafiltrate during continuous venovenous haemofiltration in patients with sepsis

European Journal of Anaesthesiology

Volumn 16, Issue 8, 1999, Pages 539-542

  Bohrer H ^a   Mieck, U ^a   Hofmann, R ^a   Klevesath, M S ^a   Nawroth, P P ^a   Martin, E ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Haemofiltration; Hormone:leptin; Sepsis

Indexed keywords

ALBUMIN; LEPTIN;

ADIPOCYTE; ADULT; AGED; ARTICLE; CLINICAL ARTICLE; ENERGY EXPENDITURE; FEMALE; HEMOFILTRATION; HORMONE BLOOD LEVEL; HUMAN; MALE; MULTIPLE ORGAN FAILURE; SEPSIS; TIME;

AGED; FEMALE; HEMOFILTRATION; HUMANS; INTENSIVE CARE UNITS; KINETICS; LEPTIN; MALE; SEPSIS; SERUM ALBUMIN;

EID: 0345061690     PISSN: 02650215     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2346.1999.00535.x     Document Type: Article

References (17)

1. Revhaug A (ed). Acute catabolic state. Update in Intensive Care and Emergency Medicine, Vol. 21. Berlin Heidelberg: Springer, 1996.
2. Cerra FB, Siegel JH, Colernan B, Border JR, McMenamy PR. Septic autocannibalism. A failure of exogenous nutritional support. Ann Surg 1980; 192: 570-580.
3. Auwerx J, Staels B. Leptin. Lancet 1998; 351: 737-742.
4. Maffei M, Halaas J, Ravussin E et al. Leptin-levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nature Med 1995; 1: 1155-1161.
5. Hickey MS, Considine RV, Israel RG et al. Leptin is related to body fat content in male distance runners. Am J Physiol 1996; 271: E938-E940.
6. Tuorninen JA, Ebeling P, Heiman IVIL, Stephens T, Koivisto VA. Leptin and thermogenesis in humans. Acta Physiol Scand 1997; 160: 83-87.
7. Esler M, Vaz M, Collier G et al. Leptin in human plasma is derived in part from the brain, and cleared by the kidneys. Lancet 1998; 351: 879.
8. Bornstein SR, Licinio J, Tauchnitz R et al. Plasma leptin levels are increased in survivors of acute sepsis: associated loss of diurnal rhythm, in cortisol and leptin secretion. J Clin Endocrinol Metab 1998; 83: 280-283.
9. Cumin F, Baum HP, Levens N. Leptin is cleared from the circulation primarily by the kidney. Int J Obes Rel Metab Dis 1996; 20: 1120-1126.
10. Meyer C, Robson D, Rackovsky N, Nadkarni V, Gerich J. Role of the kidney in human leptin metabolism. Am J Physiol 1997; 273: E903-E907.
11. Bone RC, Balk RA, Cerra FB et al. American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med 1992; 20: 864-874.
12. Wieshoizer M, Harm F, Hauser AC, Pribasnig A, Balcke P. Inappropriately high plasma leptin levels in obese haemodialysis patients can be reduced by high flux haemodialysis and haemodlafiltration. Clin Sci 1998; 94: 431-435.
13. Göhl H, Buck R, Strathmann H. Basic features of polyamide membranes. Contrib Nephrol 1992; 96: 1-25.
14. Ferron F, Considine RV, Peino R, Lado IG, Dieguez Q, Casanueva FF. Serum leptin concentrations in patients with anorexia nervosa, bulimia nervosa and non-specific eating disorders correlate with the body mass index but are independent of the respective disease. Clin Endocrinot 1997; 46: 289-293.
15. Clapham JC, Smith SA, Moore GB et al. Plasma leptin concentrations and OB gene expression in subcutaneous adipose tissue are not regulated acutely by physiological hyperinsulinaemia in lean and obese humans. Int J Obes Rel Metab Dis 1997; 21: 179-183.
16. Merabet E, Dagogo-Jack S, Coyne DW et al. Increased plasma leptin concentration in end-stage renal disease. J Clin Endocrinol Metab 1997; 82: 847-850.
17. Van den Berghe G, Wouters P, Carisson L, Baxter RC, Bouillon R, Bowers CY. Leptin levels in protracted critical illness: effects of growth hormone-secretagogues and thyrotropin-releasing hormone. J Clin Endocrinol Metab 1998; 83: 3062-3070.