메뉴 건너뛰기




Volumn 46, Issue 2, 2003, Pages 202-211

Sodium Butyrate Inhibits Cell Growth and Stimulates p21 WAF1/CIP1 Protein in Human Colonic Adenocarcinoma Cells Independently of p53 Status

Author keywords

[No Author keywords available]

Indexed keywords

BUTYRIC ACID; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLIN DEPENDENT KINASE INHIBITOR 1; MESSENGER RNA; PROTEIN; PROTEIN P53; UNCLASSIFIED DRUG;

EID: 0345059371     PISSN: 01635581     EISSN: None     Source Type: Journal    
DOI: 10.1207/S15327914NC4602_14     Document Type: Article
Times cited : (26)

References (51)
  • 1
    • 0024312651 scopus 로고
    • High-fiber diets: Influence on characteristics of cecal digesta including short-chain fatty acid concentrations and pH
    • Fleming SE, Fitch MD, and Chansler MW: High-fiber diets: influence on characteristics of cecal digesta including short-chain fatty acid concentrations and pH. Am J Clin Nutr 50, 93-99, 1989.
    • (1989) Am J Clin Nutr , vol.50 , pp. 93-99
    • Fleming, S.E.1    Fitch, M.D.2    Chansler, M.W.3
  • 2
    • 0034897126 scopus 로고    scopus 로고
    • Butyrate and propionate downregulate ERK phosphorylation in HT-29 colon carcinoma cells prior to differentiation
    • Davido DJ, Richter F, Boxberger F, Stahl A, Menzel T, et al.: Butyrate and propionate downregulate ERK phosphorylation in HT-29 colon carcinoma cells prior to differentiation. Eur J Cancer Prev 10, 313-321, 2001.
    • (2001) Eur J Cancer Prev , vol.10 , pp. 313-321
    • Davido, D.J.1    Richter, F.2    Boxberger, F.3    Stahl, A.4    Menzel, T.5
  • 3
    • 0031896444 scopus 로고    scopus 로고
    • Differential modulation of human (Caco-2) colon cancer cell line phenotype by short chain fatty acids
    • Basson MD, Emenaker NJ, and Hong F: Differential modulation of human (Caco-2) colon cancer cell line phenotype by short chain fatty acids. Proc Soc Exp Biol Med 217, 476-483, 1998.
    • (1998) Proc Soc Exp Biol Med , vol.217 , pp. 476-483
    • Basson, M.D.1    Emenaker, N.J.2    Hong, F.3
  • 4
    • 0026786802 scopus 로고
    • Effects of short-chain fatty acids on growth and differentiation of the human colon-cancer cell line HT29
    • Gamet L, Daviaud D, Denis-Pouxviel C, Remesy C, and Murat JC: Effects of short-chain fatty acids on growth and differentiation of the human colon-cancer cell line HT29. Int J Cancer 52, 286-289, 1992.
    • (1992) Int J Cancer , vol.52 , pp. 286-289
    • Gamet, L.1    Daviaud, D.2    Denis-Pouxviel, C.3    Remesy, C.4    Murat, J.C.5
  • 5
    • 0035105352 scopus 로고    scopus 로고
    • Short chain fatty acids differentially modulate cellular phenotype and c-myc protein levels in primary human nonmalignant and malignant colonocytes
    • Emenaker NJ and Basson MD: Short chain fatty acids differentially modulate cellular phenotype and c-myc protein levels in primary human nonmalignant and malignant colonocytes. Dig Dis Sci 46, 96-105, 2001.
    • (2001) Dig Dis Sci , vol.46 , pp. 96-105
    • Emenaker, N.J.1    Basson, M.D.2
  • 6
    • 0035165096 scopus 로고    scopus 로고
    • Short-chain fatty acids inhibit invasive human colon cancer by modulating uPA, TIMP-1, TIMP-2, mutant p53, Bcl-2, Bax, p21 and PCNA protein expression in an in vitro cell culture model
    • Emenaker NJ, Calaf GM, Cox D, Basson MD, and Qureshi N: Short-chain fatty acids inhibit invasive human colon cancer by modulating uPA, TIMP-1, TIMP-2, mutant p53, Bcl-2, Bax, p21 and PCNA protein expression in an in vitro cell culture model. J Nutr 131, 3041S-3046S, 2001.
    • (2001) J Nutr , vol.131
    • Emenaker, N.J.1    Calaf, G.M.2    Cox, D.3    Basson, M.D.4    Qureshi, N.5
  • 7
    • 0033276680 scopus 로고    scopus 로고
    • Butyrate switches the pattern of chemokine secretion by intestinal epithelial cells through histone acetylation
    • Fusunyan RD, Quinn JJ, Fujimoto M, MacDermott RP, and Sanderson IR: Butyrate switches the pattern of chemokine secretion by intestinal epithelial cells through histone acetylation. Mol Med 5, 631-640, 1999.
    • (1999) Mol Med , vol.5 , pp. 631-640
    • Fusunyan, R.D.1    Quinn, J.J.2    Fujimoto, M.3    MacDermott, R.P.4    Sanderson, I.R.5
  • 8
    • 0027617675 scopus 로고
    • Butyrate rapidly induces growth inhibition and differentiation in HT-29 cells
    • Barnard JA and Warwick G: Butyrate rapidly induces growth inhibition and differentiation in HT-29 cells. Cell Growth Differ 4, 495-501, 1993.
    • (1993) Cell Growth Differ , vol.4 , pp. 495-501
    • Barnard, J.A.1    Warwick, G.2
  • 9
    • 0022978527 scopus 로고
    • Effects of short chain fatty acids on a new human colon carcinoma cell line (LIM1215)
    • Whitehead RH, Young GP, and Bhathal PS: Effects of short chain fatty acids on a new human colon carcinoma cell line (LIM1215). Gut 27, 1457-1463, 1986.
    • (1986) Gut , vol.27 , pp. 1457-1463
    • Whitehead, R.H.1    Young, G.P.2    Bhathal, P.S.3
  • 10
    • 0028286187 scopus 로고
    • Potentiation by specific short-chain fatty acids of differentiation and apoptosis in human colonic carcinoma cell lines
    • Heerdt BG, Houston MA, and Augenlicht LH: Potentiation by specific short-chain fatty acids of differentiation and apoptosis in human colonic carcinoma cell lines. Cancer Res 54, 3288-3293, 1994.
    • (1994) Cancer Res , vol.54 , pp. 3288-3293
    • Heerdt, B.G.1    Houston, M.A.2    Augenlicht, L.H.3
  • 12
    • 0032869696 scopus 로고    scopus 로고
    • Butyrate mediates Caco-2 cell apoptosis via up-regulation of pro-apoptotic BAK and inducing caspase-3 mediated cleavage of poly-(ADP-ribose) polymerase (PARP)
    • Ruemmele FM, Dionne S, Qureshi I, Sarma DS, Levy E, et al.: Butyrate mediates Caco-2 cell apoptosis via up-regulation of pro-apoptotic BAK and inducing caspase-3 mediated cleavage of poly-(ADP-ribose) polymerase (PARP). Cell Death Differ 6, 729-735, 1999.
    • (1999) Cell Death Differ , vol.6 , pp. 729-735
    • Ruemmele, F.M.1    Dionne, S.2    Qureshi, I.3    Sarma, D.S.4    Levy, E.5
  • 13
    • 0029058058 scopus 로고
    • Patterns of expression of lineage-specific markers during the in vitro-induced differentiation of HT29 colon carcinoma cells
    • Velcich A, Palumbo L, Jarry A, Laboisse C, Racevskis J, et al.: Patterns of expression of lineage-specific markers during the in vitro-induced differentiation of HT29 colon carcinoma cells. Cell Growth Differ 6, 749-757, 1995.
    • (1995) Cell Growth Differ , vol.6 , pp. 749-757
    • Velcich, A.1    Palumbo, L.2    Jarry, A.3    Laboisse, C.4    Racevskis, J.5
  • 14
    • 0034105047 scopus 로고    scopus 로고
    • Butyrate and trichostatin A effects on the proliferation/differentiation of human intestinal epithelial cells: Induction of cyclin D3 and p21 expression
    • Siavoshian S, Segain JP, Kornprobst M, Bonnet C, Cherbut C, et al.: Butyrate and trichostatin A effects on the proliferation/differentiation of human intestinal epithelial cells: induction of cyclin D3 and p21 expression. Gut 46, 507-514, 2000.
    • (2000) Gut , vol.46 , pp. 507-514
    • Siavoshian, S.1    Segain, J.P.2    Kornprobst, M.3    Bonnet, C.4    Cherbut, C.5
  • 15
    • 0031825739 scopus 로고    scopus 로고
    • Butyrate-induced differentiation of Caco-2 cells is associated with apoptosis and early induction of p21Waf1/Cip1 and p27Kip1
    • discussion 169-170
    • Litvak DA, Evers BM, Hwang KO, Hellmich MR, Ko TC, et al.: Butyrate-induced differentiation of Caco-2 cells is associated with apoptosis and early induction of p21Waf1/Cip1 and p27Kip1. Surgery 124, 161-169; discussion 169-170, 1998.
    • (1998) Surgery , vol.124 , pp. 161-169
    • Litvak, D.A.1    Evers, B.M.2    Hwang, K.O.3    Hellmich, M.R.4    Ko, T.C.5
  • 16
    • 0033654178 scopus 로고    scopus 로고
    • Apoptosis cascade proteins are regulated in vivo by high intracolonic butyrate concentration: Correlation with colon cancer inhibition
    • Avivi-Green C, Polak-Charcon S, Madar Z, and Schwartz B: Apoptosis cascade proteins are regulated in vivo by high intracolonic butyrate concentration: correlation with colon cancer inhibition. Oncol Res 12, 83-95, 2000.
    • (2000) Oncol Res , vol.12 , pp. 83-95
    • Avivi-Green, C.1    Polak-Charcon, S.2    Madar, Z.3    Schwartz, B.4
  • 18
    • 0034662614 scopus 로고    scopus 로고
    • Genetic reprogramming in pathways of colonic cell maturation induced by short chain fatty acids: Comparison with trichostatin A, sulindac, and curcumin and implications for chemoprevention of colon cancer
    • Mariadason JM, Corner GA, and Augenlicht LH: Genetic reprogramming in pathways of colonic cell maturation induced by short chain fatty acids: comparison with trichostatin A, sulindac, and curcumin and implications for chemoprevention of colon cancer. Cancer Res 60, 4561-4572, 2000.
    • (2000) Cancer Res , vol.60 , pp. 4561-4572
    • Mariadason, J.M.1    Corner, G.A.2    Augenlicht, L.H.3
  • 19
    • 0034710806 scopus 로고    scopus 로고
    • Inhibition by deacetylase inhibitors of IL-1-dependent induction of haptoglobin involves CCAAT/enhancer-binding protein isoforms in intestinal epithelial cells
    • Desilets A, Gheorghiu I, Yu SJ, Seidman EG, and Asselin C: Inhibition by deacetylase inhibitors of IL-1-dependent induction of haptoglobin involves CCAAT/enhancer-binding protein isoforms in intestinal epithelial cells. Biochem Biophys Res Commun 276, 673-679, 2000.
    • (2000) Biochem Biophys Res Commun , vol.276 , pp. 673-679
    • Desilets, A.1    Gheorghiu, I.2    Yu, S.J.3    Seidman, E.G.4    Asselin, C.5
  • 20
    • 0031858569 scopus 로고    scopus 로고
    • Short-chain fatty acids regulate IGF-binding protein secretion by intestinal epithelial cells
    • Nishimura A, Fujimoto M, Oguchi S, Fusunyan RD, MacDermott RP, et al.: Short-chain fatty acids regulate IGF-binding protein secretion by intestinal epithelial cells. Am J Physiol 275, E55-E63, 1998.
    • (1998) Am J Physiol , vol.275
    • Nishimura, A.1    Fujimoto, M.2    Oguchi, S.3    Fusunyan, R.D.4    MacDermott, R.P.5
  • 21
    • 0032452040 scopus 로고    scopus 로고
    • Tyrosine kinase inhibitors reverse butyrate stimulation of human Caco-2 intestinal epithelial cell alkaline phosphatase but not butyrate promotion of dipeptidyl dipeptidase
    • Basson MD and Hong F: Tyrosine kinase inhibitors reverse butyrate stimulation of human Caco-2 intestinal epithelial cell alkaline phosphatase but not butyrate promotion of dipeptidyl dipeptidase. Cell Biol Int 22, 339-344, 1998.
    • (1998) Cell Biol Int , vol.22 , pp. 339-344
    • Basson, M.D.1    Hong, F.2
  • 22
    • 0030272773 scopus 로고    scopus 로고
    • Staurosporine inhibits the proliferation, alters the cell cycle distribution and induces apoptosis in HT-29 human colon adenocarcinoma cells
    • Qiao L, Koutsos M, Tsai LL, Kozoni V, Guzman J, et al.: Staurosporine inhibits the proliferation, alters the cell cycle distribution and induces apoptosis in HT-29 human colon adenocarcinoma cells. Cancer Lett 107, 83-89, 1996.
    • (1996) Cancer Lett , vol.107 , pp. 83-89
    • Qiao, L.1    Koutsos, M.2    Tsai, L.L.3    Kozoni, V.4    Guzman, J.5
  • 23
    • 0032933432 scopus 로고    scopus 로고
    • Cooperation between phosphorylation and acetylation processes in transcriptional control
    • Espinos E, Le Van Thai A, Pomies C, and Weber MJ: Cooperation between phosphorylation and acetylation processes in transcriptional control. Mol Cell Biol 19, 3474-3484, 1999.
    • (1999) Mol Cell Biol , vol.19 , pp. 3474-3484
    • Espinos, E.1    Le Van Thai, A.2    Pomies, C.3    Weber, M.J.4
  • 24
    • 0032077613 scopus 로고    scopus 로고
    • Activation of the MAP kinase cascade by histone deacetylase inhibitors is required for the stimulation of choline acetyltransferase gene promoter
    • Espinos E and Weber MJ: Activation of the MAP kinase cascade by histone deacetylase inhibitors is required for the stimulation of choline acetyltransferase gene promoter. Brain Res Mol Brain Res 56, 118-124, 1998.
    • (1998) Brain Res Mol Brain Res , vol.56 , pp. 118-124
    • Espinos, E.1    Weber, M.J.2
  • 26
    • 0022967249 scopus 로고
    • n-Butyrate alters chromatin accessibility to DNA repair enzymes
    • Smith PJ: n-Butyrate alters chromatin accessibility to DNA repair enzymes. Carcinogenesis 7, 423-429, 1986.
    • (1986) Carcinogenesis , vol.7 , pp. 423-429
    • Smith, P.J.1
  • 27
    • 0037154738 scopus 로고    scopus 로고
    • Effect of p53 status on tumor response to antiangiogenic therapy
    • Yu JL, Rak JW, Coomber BL, Hicklin DJ, and Kerbel RS: Effect of p53 status on tumor response to antiangiogenic therapy. Science 295, 1526-1528, 2002.
    • (2002) Science , vol.295 , pp. 1526-1528
    • Yu, J.L.1    Rak, J.W.2    Coomber, B.L.3    Hicklin, D.J.4    Kerbel, R.S.5
  • 28
    • 0032701521 scopus 로고    scopus 로고
    • Disruption of p53 in human cancer cells alters the responses to therapeutic agents
    • Bunz F, Hwang PM, Torrance C, Waldman T, Zhang Y, et al.: Disruption of p53 in human cancer cells alters the responses to therapeutic agents. J Clin Invest 104, 263-269, 1999.
    • (1999) J Clin Invest , vol.104 , pp. 263-269
    • Bunz, F.1    Hwang, P.M.2    Torrance, C.3    Waldman, T.4    Zhang, Y.5
  • 29
    • 0031588377 scopus 로고    scopus 로고
    • Modulation of p53 expression in cultured colonic adenoma cell lines by the naturally occurring lumenal factors butyrate and deoxycholate
    • Palmer DG, Paraskeva C, and Williams AC: Modulation of p53 expression in cultured colonic adenoma cell lines by the naturally occurring lumenal factors butyrate and deoxycholate. Int J Cancer 73, 702-706, 1997.
    • (1997) Int J Cancer , vol.73 , pp. 702-706
    • Palmer, D.G.1    Paraskeva, C.2    Williams, A.C.3
  • 30
    • 0035821788 scopus 로고    scopus 로고
    • p21 Waf1/Cip1 can protect human colon carcinoma cells against p53-dependent and p53-independent apoptosis induced by natural chemopreventive and therapeutic agents
    • Mahyar-Roemer M and Roemer K: p21 Waf1/Cip1 can protect human colon carcinoma cells against p53-dependent and p53-independent apoptosis induced by natural chemopreventive and therapeutic agents. Oncogene 20, 3387-3398, 2001.
    • (2001) Oncogene , vol.20 , pp. 3387-3398
    • Mahyar-Roemer, M.1    Roemer, K.2
  • 31
    • 0032499756 scopus 로고    scopus 로고
    • p21 (WAF1) is required for butyrate-mediated growth inhibition of human colon cancer cells
    • Archer SY, Meng S, Shei A, and Hodin RA: p21 (WAF1) is required for butyrate-mediated growth inhibition of human colon cancer cells. Proc Natl Acad Sci USA 95, 6791-6796, 1998.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 6791-6796
    • Archer, S.Y.1    Meng, S.2    Shei, A.3    Hodin, R.A.4
  • 32
    • 0022346378 scopus 로고
    • Simian virus 40-mediated cis induction of the Xenopus beta-globin DNase I hypersensitive site
    • Enver T, Brewer AC, and Patient RK: Simian virus 40-mediated cis induction of the Xenopus beta-globin DNase I hypersensitive site. Nature 318, 680-683, 1985.
    • (1985) Nature , vol.318 , pp. 680-683
    • Enver, T.1    Brewer, A.C.2    Patient, R.K.3
  • 33
    • 0030789734 scopus 로고    scopus 로고
    • Adjacent DNA elements dominantly restrict the ubiquitous activity of a novel chromatin-opening region to specific tissues
    • Ortiz BD, Cado D, Chen V, Diaz PW, and Winoto A: Adjacent DNA elements dominantly restrict the ubiquitous activity of a novel chromatin-opening region to specific tissues. EMBO J 16, 5037-5045, 1997.
    • (1997) EMBO J , vol.16 , pp. 5037-5045
    • Ortiz, B.D.1    Cado, D.2    Chen, V.3    Diaz, P.W.4    Winoto, A.5
  • 34
    • 0035000305 scopus 로고    scopus 로고
    • Transient vs. prolonged histone hyperacetylation: Effects on colon cancer cell growth, differentiation, and apoptosis
    • Wu JT, Archer SY, Hinnebusch B, Meng S, and Hodin RA: Transient vs. prolonged histone hyperacetylation: effects on colon cancer cell growth, differentiation, and apoptosis. Am J Physiol Gastrointest Liver Physiol 280, G482-G490, 2001.
    • (2001) Am J Physiol Gastrointest Liver Physiol , vol.280
    • Wu, J.T.1    Archer, S.Y.2    Hinnebusch, B.3    Meng, S.4    Hodin, R.A.5
  • 35
    • 0343517115 scopus 로고    scopus 로고
    • TNF-alpha modulates the differentiation induced by butyrate in the HT-29 human colon adenocarcinoma cell line
    • Kovarikova M, Pachemik J, Hofmanova J, Zadak Z, and Kozubik A: TNF-alpha modulates the differentiation induced by butyrate in the HT-29 human colon adenocarcinoma cell line. Eur J Cancer 36, 1844-1852, 2000.
    • (2000) Eur J Cancer , vol.36 , pp. 1844-1852
    • Kovarikova, M.1    Pachemik, J.2    Hofmanova, J.3    Zadak, Z.4    Kozubik, A.5
  • 36
    • 0034811740 scopus 로고    scopus 로고
    • Transcriptional response of a human colon adenocarcinoma cell line to sodium butyrate
    • Iacomino G, Tecce MF, Grimaldi C, Tosto M, and Russo GL: Transcriptional response of a human colon adenocarcinoma cell line to sodium butyrate. Biochem Biophys Res Commun 285, 1280-1289, 2001.
    • (2001) Biochem Biophys Res Commun , vol.285 , pp. 1280-1289
    • Iacomino, G.1    Tecce, M.F.2    Grimaldi, C.3    Tosto, M.4    Russo, G.L.5
  • 37
    • 0033868083 scopus 로고    scopus 로고
    • Sodium butyrate modulates cell cycle-related proteins in HT29 human colonic adenocarcinoma cells
    • Coradini D, Pellizzaro C, Marimpietri D, Abolafio G, and Daidone MG: Sodium butyrate modulates cell cycle-related proteins in HT29 human colonic adenocarcinoma cells. Cell Prolif 33, 139-146, 2000.
    • (2000) Cell Prolif , vol.33 , pp. 139-146
    • Coradini, D.1    Pellizzaro, C.2    Marimpietri, D.3    Abolafio, G.4    Daidone, M.G.5
  • 38
    • 0035126973 scopus 로고    scopus 로고
    • Resistance to butyrate-induced cell differentiation and apoptosis during spontaneous Caco-2 cell differentiation
    • Mariadason JM, Velcich A, Wilson AJ, Augenlicht LH, and Gibson PR: Resistance to butyrate-induced cell differentiation and apoptosis during spontaneous Caco-2 cell differentiation. Gastroenterology 120, 889-899, 2001.
    • (2001) Gastroenterology , vol.120 , pp. 889-899
    • Mariadason, J.M.1    Velcich, A.2    Wilson, A.J.3    Augenlicht, L.H.4    Gibson, P.R.5
  • 39
    • 0030266996 scopus 로고    scopus 로고
    • Regulation of human colonic cell line proliferation and phenotype by sodium butyrate
    • Basson MD, Turowski GA, Rashid Z, Hong F, and Madri JA: Regulation of human colonic cell line proliferation and phenotype by sodium butyrate. Dig Dis Sci 41, 1989-1993, 1996.
    • (1996) Dig Dis Sci , vol.41 , pp. 1989-1993
    • Basson, M.D.1    Turowski, G.A.2    Rashid, Z.3    Hong, F.4    Madri, J.A.5
  • 40
    • 0033227940 scopus 로고    scopus 로고
    • Butyrate-induced G2/M block in Caco-2 colon cancer cells is associated with decreased p34cdc2 activity
    • Harrison LE, Wang QM, and Studzinski GP: Butyrate-induced G2/M block in Caco-2 colon cancer cells is associated with decreased p34cdc2 activity. Proc Soc Exp Biol Med 222, 150-156, 1999.
    • (1999) Proc Soc Exp Biol Med , vol.222 , pp. 150-156
    • Harrison, L.E.1    Wang, Q.M.2    Studzinski, G.P.3
  • 41
    • 0036533679 scopus 로고    scopus 로고
    • Proteome analysis of butyrate-treated human colon cancer cells (HT-29)
    • Tan S, Seow TK, Liang RC, Koh S, Lee CP, et al.: Proteome analysis of butyrate-treated human colon cancer cells (HT-29). Int J Cancer 98, 523-531, 2002.
    • (2002) Int J Cancer , vol.98 , pp. 523-531
    • Tan, S.1    Seow, T.K.2    Liang, R.C.3    Koh, S.4    Lee, C.P.5
  • 42
    • 0031594705 scopus 로고    scopus 로고
    • Nuclear accumulation of p21Cip1 at the onset of mitosis: A role at the G2/M-phase transition
    • Dulic V, Stein GH, Far DF, and Reed SI: Nuclear accumulation of p21Cip1 at the onset of mitosis: a role at the G2/M-phase transition. Mol Cell Biol 18, 546-557, 1998.
    • (1998) Mol Cell Biol , vol.18 , pp. 546-557
    • Dulic, V.1    Stein, G.H.2    Far, D.F.3    Reed, S.I.4
  • 43
    • 0032514364 scopus 로고    scopus 로고
    • p53 regulates Cdc2 independently of inhibitory phosphorylation to reinforce radiation-induced G2 arrest in human cells
    • Winters ZE, Ongkeko WM, Harris AL, and Norbury CJ: p53 regulates Cdc2 independently of inhibitory phosphorylation to reinforce radiation-induced G2 arrest in human cells. Oncogene 17, 673-684, 1998.
    • (1998) Oncogene , vol.17 , pp. 673-684
    • Winters, Z.E.1    Ongkeko, W.M.2    Harris, A.L.3    Norbury, C.J.4
  • 44
    • 0033761352 scopus 로고    scopus 로고
    • Butyrate metabolism upstream and downstream acetyl-CoA synthesis and growth control of human colon carcinoma cells
    • Leschelle X, Delpal S, Goubern M, Blottiere HM, and Blachier F: Butyrate metabolism upstream and downstream acetyl-CoA synthesis and growth control of human colon carcinoma cells. Eur J Biochem 267, 6435-6442, 2000.
    • (2000) Eur J Biochem , vol.267 , pp. 6435-6442
    • Leschelle, X.1    Delpal, S.2    Goubern, M.3    Blottiere, H.M.4    Blachier, F.5
  • 45
    • 0033963601 scopus 로고    scopus 로고
    • Involvement of p21(Waf1/Cip1) and its cleavage by DEVD-caspase during apoptosis of colorectal cancer cells induced by butyrate
    • Chai F, Evdokiou A, Young GP, and Zalewski PD: Involvement of p21(Waf1/Cip1) and its cleavage by DEVD-caspase during apoptosis of colorectal cancer cells induced by butyrate. Carcinogenesis 21, 7-14, 2000.
    • (2000) Carcinogenesis , vol.21 , pp. 7-14
    • Chai, F.1    Evdokiou, A.2    Young, G.P.3    Zalewski, P.D.4
  • 46
    • 0030772026 scopus 로고    scopus 로고
    • Butyrate activates the WAF1/Cip1 gene promoter through Sp1 sites in a p53-negative human colon cancer cell line
    • Nakano K, Mizuno T, Sowa Y, Orita T, Yoshino T, et al.: Butyrate activates the WAF1/Cip1 gene promoter through Sp1 sites in a p53-negative human colon cancer cell line. J Biol Chem 272, 22199-22206, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 22199-22206
    • Nakano, K.1    Mizuno, T.2    Sowa, Y.3    Orita, T.4    Yoshino, T.5
  • 47
    • 0031855537 scopus 로고    scopus 로고
    • Butyrate inhibits colon carcinoma cell growth through two distinct pathways
    • Archer S, Meng S, Wu J, Johnson J, Tang R, et al.: Butyrate inhibits colon carcinoma cell growth through two distinct pathways. Surgery 124, 248-253, 1998.
    • (1998) Surgery , vol.124 , pp. 248-253
    • Archer, S.1    Meng, S.2    Wu, J.3    Johnson, J.4    Tang, R.5
  • 48
    • 0034718784 scopus 로고    scopus 로고
    • Sp1 and Sp3 activate p21 (WAF1/CIP1) gene transcription in the Caco-2 colon adenocarcinoma cell line
    • Gartel AL, Goufman E, Najmabadi F, and Tyner AL: Sp1 and Sp3 activate p21 (WAF1/CIP1) gene transcription in the Caco-2 colon adenocarcinoma cell line. Oncogene 19, 5182-5188, 2000.
    • (2000) Oncogene , vol.19 , pp. 5182-5188
    • Gartel, A.L.1    Goufman, E.2    Najmabadi, F.3    Tyner, A.L.4
  • 49
    • 0030741385 scopus 로고    scopus 로고
    • Apoptotic death in adenocarcinoma cell lines induced by butyrate and other histone deacetylase inhibitors
    • McBain JA, Eastman A, Nobel CS, and Mueller GC: Apoptotic death in adenocarcinoma cell lines induced by butyrate and other histone deacetylase inhibitors. Biochem Pharmacol 53, 1357-1368, 1997.
    • (1997) Biochem Pharmacol , vol.53 , pp. 1357-1368
    • McBain, J.A.1    Eastman, A.2    Nobel, C.S.3    Mueller, G.C.4
  • 50
    • 0034610814 scopus 로고    scopus 로고
    • The language of covalent histone modifications
    • Strahl BD and Allis CD: The language of covalent histone modifications. Nature 403, 41-45, 2000.
    • (2000) Nature , vol.403 , pp. 41-45
    • Strahl, B.D.1    Allis, C.D.2
  • 51
    • 0033199611 scopus 로고    scopus 로고
    • Sp3, but not Sp1, mediates the transcriptional activation of the p21/WAF1/Cip1 gene promoter by histone deacetylase inhibitor
    • Sowa Y, Orita T, Minamikawa-Hiranabe S, Mizuno T, Nomura H, et al.: Sp3, but not Sp1, mediates the transcriptional activation of the p21/WAF1/Cip1 gene promoter by histone deacetylase inhibitor. Cancer Res 59, 4266-4270, 1999.
    • (1999) Cancer Res , vol.59 , pp. 4266-4270
    • Sowa, Y.1    Orita, T.2    Minamikawa-Hiranabe, S.3    Mizuno, T.4    Nomura, H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.