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Volumn 189, Issue 8, 1999, Pages 1207-1216

Targeted gene disruption reveals an adhesin indispensable for pathogenicity of Blastomyces dermatitidis

Author keywords

Adhesin; Dimorphic fungi; Gene targeting; Pathogenic mechanism; Virulence factor

Indexed keywords

ADHESIN;

EID: 0345005002     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.189.8.1207     Document Type: Article
Times cited : (129)

References (36)
  • 1
    • 0028568541 scopus 로고
    • The emerging fungal threat
    • Sternberg, S. 1994. The emerging fungal threat. Science. 266: 1632-1634.
    • (1994) Science , vol.266 , pp. 1632-1634
    • Sternberg, S.1
  • 2
    • 0345630065 scopus 로고
    • Comparative study of pulmonary mycoses in the United States and Canada
    • Pan American Sanitary Bureau Scientific Publication No. 205, Washington, D.C.
    • Ajello, L. 1970. Comparative study of pulmonary mycoses in the United States and Canada. In Proceedings of the Pan American Health Organization International Symposium on the Mycoses. Pan American Sanitary Bureau Scientific Publication No. 205, Washington, D.C. 3-10.
    • (1970) Proceedings of the Pan American Health Organization International Symposium on the Mycoses , pp. 3-10
    • Ajello, L.1
  • 3
    • 0026653927 scopus 로고
    • Isolation of telomerelike sequences from Cryptococcus neoformans and their use in high-efficiency transformation
    • Edman, J.C. 1992. Isolation of telomerelike sequences from Cryptococcus neoformans and their use in high-efficiency transformation. Mol. Cell. Biol. 12:2777-2783.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 2777-2783
    • Edman, J.C.1
  • 4
    • 0027192868 scopus 로고
    • Isogenic strain construction and gene mapping in Candida albicans
    • Fonzi, W.A., and M.Y. Irwin. 1993. Isogenic strain construction and gene mapping in Candida albicans. Genetics. 134: 717-728.
    • (1993) Genetics , vol.134 , pp. 717-728
    • Fonzi, W.A.1    Irwin, M.Y.2
  • 5
    • 0021058008 scopus 로고
    • The new yeast genetics
    • Struhl, K. 1983. The new yeast genetics. Nature. 305:391-397.
    • (1983) Nature , vol.305 , pp. 391-397
    • Struhl, K.1
  • 6
    • 0025012763 scopus 로고
    • Isolation, purification and radiolabeling of a novel 120 kD surface protein on Blastomyces dermatitidis yeasts to detect antibody in infected patients
    • Klein, D.S., and J.M. Jones. 1990. Isolation, purification and radiolabeling of a novel 120 kD surface protein on Blastomyces dermatitidis yeasts to detect antibody in infected patients. J. Clin. Invest. 85:152-161.
    • (1990) J. Clin. Invest. , vol.85 , pp. 152-161
    • Klein, B.S.1    Jones, J.M.2
  • 7
    • 0027326768 scopus 로고
    • Immunologic recognition of a 25-amino acid repeat arrayed in tandem on a major antigen of Blastomyces dermatitidis
    • Klein, B.S., L.H. Hogan, and J.M.Jones. 1993. Immunologic recognition of a 25-amino acid repeat arrayed in tandem on a major antigen of Blastomyces dermatitidis. J. Clin. Invest. 92: 330-337.
    • (1993) J. Clin. Invest. , vol.92 , pp. 330-337
    • Klein, B.S.1    Hogan, L.H.2    Jones, J.M.3
  • 8
    • 0029609797 scopus 로고
    • Genomic cloning, characterization, and functional analysis of the major surface adhesin WI-1 on Blastomyces dermatitidis yeasts
    • Hogan, L.H., S. Josvai, and B.S. Klein, 1995. Genomic cloning, characterization, and functional analysis of the major surface adhesin WI-1 on Blastomyces dermatitidis yeasts. J. Biol. Chem. 270:30725-30732.
    • (1995) J. Biol. Chem. , vol.270 , pp. 30725-30732
    • Hogan, L.H.1    Josvai, S.2    Klein, B.S.3
  • 9
    • 0028878721 scopus 로고
    • The WI-1 antigen on Blastomyces dermatitidis yeasts mediates binding to human macrophage CD18 and CD14 receptors
    • Newman, S.L., S. Chaturvedi, and B.S. Klein. 1995. The WI-1 antigen on Blastomyces dermatitidis yeasts mediates binding to human macrophage CD18 and CD14 receptors. J. Immunol. 154:753-761.
    • (1995) J. Immunol. , vol.154 , pp. 753-761
    • Newman, S.L.1    Chaturvedi, S.2    Klein, B.S.3
  • 10
    • 0028085588 scopus 로고
    • Altered expression of the surface protein WI-1 in genetically related strains of Blastomyces dermatitidis that differ in virulence regulates recognition of yeasts by human macrophages
    • Klein, B.S., S. Chaturvedi, L.H. Hogan, J.M. Jones, and S.L. Newman. 1994. Altered expression of the surface protein WI-1 in genetically related strains of Blastomyces dermatitidis that differ in virulence regulates recognition of yeasts by human macrophages. Infect. Immun. 62:3536-3542.
    • (1994) Infect. Immun. , vol.62 , pp. 3536-3542
    • Klein, B.S.1    Chaturvedi, S.2    Hogan, L.H.3    Jones, J.M.4    Newman, S.L.5
  • 11
    • 0029896422 scopus 로고    scopus 로고
    • Role of cell surface molecules on Blastomyces dermatitidis in host:Pathogen interactions
    • Klein, B.S., and S.L. Newman. 1996. Role of cell surface molecules on Blastomyces dermatitidis in host:pathogen interactions. Trends Microbicl. 4:246-251.
    • (1996) Trends Microbicl. , vol.4 , pp. 246-251
    • Klein, B.S.1    Newman, S.L.2
  • 12
    • 0007445035 scopus 로고    scopus 로고
    • Surface molecules on Blastomyces dermatitidis and their role in virulence
    • Klein, B.S., L.H. Hogan, and S.L. Newman. 1997. Surface molecules on Blastomyces dermatitidis and their role in virulence. Am. Soc. Microbiol. News. 63:140-145.
    • (1997) Am. Soc. Microbiol. News , vol.63 , pp. 140-145
    • Klein, B.S.1    Hogan, L.H.2    Newman, S.L.3
  • 13
    • 0031020493 scopus 로고    scopus 로고
    • Transforming DNA integrates at multiple sites in the dimorphic fungal pathogen Blastomyces dermatitidis
    • Hogan, L.H., and B.S. Klein. 1997. Transforming DNA integrates at multiple sites in the dimorphic fungal pathogen Blastomyces dermatitidis. Gene. 186:219-226.
    • (1997) Gene , vol.186 , pp. 219-226
    • Hogan, L.H.1    Klein, B.S.2
  • 14
    • 0018142478 scopus 로고
    • Mouse model of pulmonary blastomycosis: Utility, simplicity, and quantitative parameters
    • Harvey, R.P., E.S. Schmid, C.C. Carrington, and D.A. Stevens. 1978. Mouse model of pulmonary blastomycosis: Utility, simplicity, and quantitative parameters. Am. Rev. Respir. Dis. 117:695-703.
    • (1978) Am. Rev. Respir. Dis. , vol.117 , pp. 695-703
    • Harvey, R.P.1    Schmid, E.S.2    Carrington, C.C.3    Stevens, D.A.4
  • 16
    • 0002099731 scopus 로고    scopus 로고
    • A series of vectors for fungal transformation
    • Sweigard, J. 1997. A series of vectors for fungal transformation. Fungal Genetics Newsletter. 44:52-53.
    • (1997) Fungal Genetics Newsletter , vol.44 , pp. 52-53
    • Sweigard, J.1
  • 17
    • 84907123709 scopus 로고
    • Quantitative plating of Histoplasma capsulatum without addition of conditioned medium or siderophores
    • Worsham, P.L., and W.E. Goldman. 1988. Quantitative plating of Histoplasma capsulatum without addition of conditioned medium or siderophores. J. Med. Vet. Mycol. 26:137-143.
    • (1988) J. Med. Vet. Mycol. , vol.26 , pp. 137-143
    • Worsham, P.L.1    Goldman, W.E.2
  • 18
    • 0021684371 scopus 로고
    • An immunological method for detecting gene expression in yeast colonies
    • Lyons, S., and N. Nelson. 1984. An immunological method for detecting gene expression in yeast colonies. Proc. Natl. Acad. Sci. USA. 81:7426-7430.
    • (1984) Proc. Natl. Acad. Sci. USA , vol.81 , pp. 7426-7430
    • Lyons, S.1    Nelson, N.2
  • 19
    • 0028021982 scopus 로고
    • Purification and characterization of the major antigen WI-1 from Blastomyces dermatitidis yeasts, and immunological comparison with A antigen
    • Klein, B.S., and J.M. Jones. 1994. Purification and characterization of the major antigen WI-1 from Blastomyces dermatitidis yeasts, and immunological comparison with A antigen. Infect. Immun. 62:3890-3900.
    • (1994) Infect. Immun. , vol.62 , pp. 3890-3900
    • Klein, B.S.1    Jones, J.M.2
  • 20
    • 0024557027 scopus 로고
    • Transformation in fungi
    • Fincham, J.R. 1989. Transformation in fungi. Microkiol. Rev. 53:148-170.
    • (1989) Microkiol. Rev. , vol.53 , pp. 148-170
    • Fincham, J.R.1
  • 21
    • 0028962897 scopus 로고
    • Ectopic integration of transforming DNA is rare among Neurospora transformants selected for gene replacement
    • Miao, V.P., M.R. Rountree, and E.U. Selker. 1995. Ectopic integration of transforming DNA is rare among Neurospora transformants selected for gene replacement. Genetics. 139: 1533-1544.
    • (1995) Genetics , vol.139 , pp. 1533-1544
    • Miao, V.P.1    Rountree, M.R.2    Selker, E.U.3
  • 22
    • 0026549480 scopus 로고
    • Killing of virulent Mycobacterium tuberculosis by reactive nitrogen intermediates produced by activated murine macrophages
    • Chan, J., Y. Xing, R.S. Magliozzo, and B.R. Bloom. 1992. Killing of virulent Mycobacterium tuberculosis by reactive nitrogen intermediates produced by activated murine macrophages. J. Exp. Med. 175:1111-1122.
    • (1992) J. Exp. Med. , vol.175 , pp. 1111-1122
    • Chan, J.1    Xing, Y.2    Magliozzo, R.S.3    Bloom, B.R.4
  • 23
    • 0028208839 scopus 로고
    • Therapeutic efficacy of monoclonal antibodies to Cryptococcus neoformans glucuronoxylomannan alone and in combination with amphotericin B
    • Mukherjee, J., L.S. Zuckier, M.D. Scharff, and A. Casadevall. 1994. Therapeutic efficacy of monoclonal antibodies to Cryptococcus neoformans glucuronoxylomannan alone and in combination with amphotericin B. Antimicrob. Agents Chemother. 38:580-587.
    • (1994) Antimicrob. Agents Chemother. , vol.38 , pp. 580-587
    • Mukherjee, J.1    Zuckier, L.S.2    Scharff, M.D.3    Casadevall, A.4
  • 25
    • 0028929002 scopus 로고
    • Antibodies to Cryptococcus neoformans glucuronoxylomannan enhance antifungal activity of murine macrophages
    • Mukherjee, J., S.C. Lee, and A. Casadevall. 1995. Antibodies to Cryptococcus neoformans glucuronoxylomannan enhance antifungal activity of murine macrophages. Infect. Immun. 63: 573-579.
    • (1995) Infect. Immun. , vol.63 , pp. 573-579
    • Mukherjee, J.1    Lee, S.C.2    Casadevall, A.3
  • 26
    • 0025748681 scopus 로고
    • Improvements and important considerations of an ex vivo assay to study Candida albicans-splenic tissue interactions
    • Riesselman, M.H., T. Kanbe, and J. Cutler. 1991. Improvements and important considerations of an ex vivo assay to study Candida albicans-splenic tissue interactions. J. Immunol. Methods. 145:153-160.
    • (1991) J. Immunol. Methods , vol.145 , pp. 153-160
    • Riesselman, M.H.1    Kanbe, T.2    Cutler, J.3
  • 27
    • 0032438166 scopus 로고    scopus 로고
    • Immunogenicity and protective efficacy of the WI-1 adhesin of Blastomyces dermtatitidis
    • Wüthrich, M., W.L. Chang, and B.S. Klein. 1998. Immunogenicity and protective efficacy of the WI-1 adhesin of Blastomyces dermtatitidis. Infect. Immun. 66:5443-5449.
    • (1998) Infect. Immun. , vol.66 , pp. 5443-5449
    • Wüthrich, M.1    Chang, W.L.2    Klein, B.S.3
  • 30
    • 0028128482 scopus 로고
    • Altered expression of α-(1,3)-glucan on genetically related strains of Blastomyces dermatitidis that differ in virulence
    • Hogan, L.H., and B.S. Klein. 1994. Altered expression of α-(1,3)-glucan on genetically related strains of Blastomyces dermatitidis that differ in virulence. Infect. Immun. 62:3543-3546.
    • (1994) Infect. Immun. , vol.62 , pp. 3543-3546
    • Hogan, L.H.1    Klein, B.S.2
  • 31
    • 0024041593 scopus 로고
    • Molecular Koch's postulates applied to microbial pathogenicity
    • Falkow, S. 1988. Molecular Koch's postulates applied to microbial pathogenicity. Rev. Infect. Dis. 10:S274-S276.
    • (1988) Rev. Infect. Dis. , vol.10
    • Falkow, S.1
  • 33
    • 0026743345 scopus 로고
    • In vivo generation of linear plasmids with addition of telomeric sequences by Histoplasma capsulatum
    • Woods, J.P., and W.E. Goldman. 1993. In vivo generation of linear plasmids with addition of telomeric sequences by Histoplasma capsulatum. Mol. Microbiol. 6:3603-3610.
    • (1993) Mol. Microbiol. , vol.6 , pp. 3603-3610
    • Woods, J.P.1    Goldman, W.E.2
  • 34
    • 0027465262 scopus 로고
    • Autonomous replication of foreign DNA in Histoplasma capsulatum: Role of native telomeric sequences
    • Woods, J.P., and W.E. Goldman. 1993. Autonomous replication of foreign DNA in Histoplasma capsulatum: role of native telomeric sequences. J. Bacteriol. 175:636-641.
    • (1993) J. Bacteriol. , vol.175 , pp. 636-641
    • Woods, J.P.1    Goldman, W.E.2
  • 35
    • 0031690616 scopus 로고    scopus 로고
    • Rare homologous gene targeting in Histoplasma capsulatum: Disruption of the URA5Hc gene by allelic replacement
    • Woods, J.P., D.M. Retallack, E.L. Heinecke, and W.E. Goldman. 1998. Rare homologous gene targeting in Histoplasma capsulatum: disruption of the URA5Hc gene by allelic replacement. J Bacteriol. 180:5135-5143.
    • (1998) J Bacteriol. , vol.180 , pp. 5135-5143
    • Woods, J.P.1    Retallack, D.M.2    Heinecke, E.L.3    Goldman, W.E.4
  • 36
    • 0025678482 scopus 로고
    • Consecutive inactivation of both alleles of the pim-1 proto-oncogene by homologous recombination in embryonic stem cells
    • te Riele, H., E.R. Maandag, A. Clarke, M. Hooper, and A. Berns. 1990. Consecutive inactivation of both alleles of the pim-1 proto-oncogene by homologous recombination in embryonic stem cells. Nature. 348:649-651.
    • (1990) Nature , vol.348 , pp. 649-651
    • Te Riele, H.1    Maandag, E.R.2    Clarke, A.3    Hooper, M.4    Berns, A.5


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