Relation between exploratory activity and immune function in aged mice: A preliminary study

Mechanisms of Ageing and Development

Volumn 102, Issue 2-3, 1998, Pages 263-277

  De La Fuente, Mónica ^a   Miñano, Marta ^a   Manuel Victor, Victor ^a   Del Rio, Mónica ^a   Dolores Ferrández, Maria ^a   Díez, Araceli ^b   Miquel, Jaime ^b  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b UNIVERSITY OF ALICANTE   (Spain)

Author keywords

Aging; Exploratory behavior; Immune function; Leukocytes; Mice

Indexed keywords

CONCANAVALIN A; MITOGENIC AGENT; SUPEROXIDE;

AGED; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AXILLARY LYMPH NODE; CELL ACTIVITY; CELL ADHESION; CELL METABOLISM; CELL MOTILITY; CELL SUSPENSION; CHEMOTAXIS; CONFERENCE PAPER; CONTROLLED STUDY; EXPLORATORY BEHAVIOR; FEMALE; IMMUNE SYSTEM; LEUKOCYTE; LONGEVITY; LYMPHOCYTE; LYMPHOCYTE PROLIFERATION; MACROPHAGE; MAZE TEST; NATURAL KILLER CELL; NONHUMAN; PERITONEUM CELL; PRIORITY JOURNAL; SENESCENCE; SPLEEN; THYMUS;

AGING; ANIMALS; FEMALE; KILLER CELLS, NATURAL; MACROPHAGES, PERITONEAL; MICE; SUPEROXIDES;

ANIMALIA;

EID: 0344972123     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0047-6374(98)00015-3     Document Type: Conference Paper

References (39)

1. Ackerman, K.D., Bellinger, D.L., Felten, S.Y., Felten, D.L., 1991. Ontogeny and senescence of noragrenergic innervation of the rodent thymus and spleen. In: Ader, R., Felten, D.L., Cohen, N. (Eds.) Psychoneuroimmunology, Academic Press, London, pp. 71-125.
2. Ader R., Felten D., Cohen N. Interaction between the bran and the immune system. Annu. Rev. Pharmacol. Toxicol. 30:1990;561-602.
3. Berke, G., 1989. Functions and mechanisms of lysis induced by cytotoxic T lymphocytes and natural killer cells. In: Paul, W.E. (Ed.) Fundamental immunology, Raven Press, N.Y.
4. Blalock J.E. The syntax of immune-neuroendocrine communication. Immunol. Today. 15:1994;504-511.
5. Borkan G.A., Norris A.H. Assessment of biological age using a profile of physical parameters. J. Gerontol. 22:1976;428-437.
6. Boyden S.V. The chemotaxis effect of mixtures of antibody and antigen on polymorphonuclear leukocytes. J. Exp. Med. 115:1962;453-456.
7. Boyun A. Separation of leucocytes from blood and bone marrow. Scand. J. Clin. Lab. Invest. 21:1968;77-82.
8. Decker T., Lohmann-Matthes M.L. A quick and simple method for the quantitation of lactate dehydrogenase release in measurements of cellular cytotoxicity and tumor necrosis factor (TNF) activity. J. Neuroimmunol. 38:1988;61-70.
9. De la Fuente M., Hemanz A., Collazos M.E., Barriga C., Ortega E. Effects of physical exercise and aging on ascorbic acid and superoxide anion levels in peritoneal macrophages from mice and guinea pigs. J. Comp. Phys. B. 165:1995;315-319.
10. De la Fuente M., del Rio M., Hernanz A. Stimulation of natural killer and antibody-dependent cellular cytotoxicity activities in mouse leukocytes by bombesin, gastrin-releasing peptide and neuromedin C: involvement of cyclic AMP, inositol 1,4,5-triphosphate and protein kinase C. J. Neuroimmunol. 48:1993;143-150.
11. De la Fuente M., Del Rio M., Ferrández M.D., Hernanz A. Modulation of phagocytic function in murine peritoneal macrophages by bombesin, gastrin-releasing peptide and neuromedin C. Immunology. 73:1991;205-211.
12. De la Fuente M. Changes in the macrophage function with aging. Comp. Biochem. Physiol. 81A:1985;935-938.
13. Del Rio M., De la Fuente M. Stimulation of natural killer (NK) and antibody-dependent cellular cytotoxicity (ADCC) activities in murine leukocytes by bombesin-related peptides requires the presence of adherent cells. Regul. Pept. 60:1995;159-166.
14. Del Rio M., Hernanz A., De la Fuente M. Bombesin, gastrin-releasing peptide and neuromedin C modulate murine lymphocyte proliferation through adherent accesory cells and activate protein kinase C. Peptides. 15:1994;15-22.
15. Doherty D.E., Haslett C., Fonnesen M.G., Henson P.M. Human monocyte adherence: a primary effect of chemotactic factors on the monocyte to stimulate adherence to human endothelium. J. Immunol. 138:1987;1762-1771.
16. Fabris N. Neuroendocrine-immune interactions: a theoretical approach to ageing. Arch. Gerontol. Geriatr. 12:1991;219-230.
17. Fabris, N., 1986. Pathways of neuroendocrine-immune interactions and their impact with aging processes. In: Facchini, A., Haaijaman, J.J., Labó, G. (Eds.), Immunoregulation in Aging, Eurage, Rijswijk, pp. 117-130.
18. Felten, D.L., Cohen, N., Ader, R., Felten, S.R., Carlson, S.L., Roszman, T.L., 1991. Central neural circuits involved in neural-immune interactions. In: Ader, R., Felten D.L., Cohen, N. (Eds.) Psychoneuroimmunology, Academic Press, London, pp. 3-25.
19. Felten, S.Y., Felten, D.L., 1991. Inervation of lymphoid tissue. In: Ader, R., Felten, D.L., Cohen, N. (Eds.) Psychoneuroimmunology, Academic Press, London, pp. 27-69.
20. Ferrández M.D., De la Fuente M. Changes with aging, sex and physical exercise in murine natural killer activity and antibody-dependent cellular cytotoxicity. Mech. Ageing Dev. 86:1996;83-94.
21. Ferrandiz M.L., Martinez M., DeJuan E., Diez A., Bustos G., Miquel J. Impairment of mitochondrial oxidative phosphorylation in brain of aged mice. Brain Res. 644:1994;335-338.
22. Gilad G.M., Gilad V.H. Strain, stress, neurodegeneration and longevity. Mech. Ageing Dev. 78:1995;75-83.
23. Klein A.W. Synaptic density correlated with maze performance in young and aged rats. A preliminary study. Mech. Ageing Dev. 21:1983;245-255.
24. Lehtonen L., Eskola J., Vainio O., Lehtonen A. Changes in lymphocyte subsets and immune competence in very advanced age. J. Gerontol. 45:1990;M108-112.
25. Mackay C.R., Imhof B.A. Cell adhesion in the immune system. Immunol. Today. 14:1993;99-102.
26. Madden K.S., Felten L. Experimental basis for neural-immune interactions. Physiol. Rev. 75:1995;77-106.
27. Makinodan T., Hahn T.J., McDougall S., Yamaguchi D.T., Fang M., Lida-Klein A. Cellular immunosenescence: an overview. Exp. Gerontol. 26:1991;281-288.
28. Ordy J.M., Rolsten C., Samorajski T., Collins R.L. Environmental stress and biological ageing. Nature. 204:1964;724-727.
29. Ortega E., Barriga C., De la Fuente M. Aging and the non-specific immune response. Facts Res. Gerontol. 7:1993;23-29.
30. Pawelec G., Adibzadeh M., Solana R., Becman I. The T-cell in the ageing individual. Mech. Ageing Dev. 93:1997;35-45.
31. Pawelec G. Molecular and cell biological studies of ageing and their application to considerations of T lymphocyte immunosenescence. Mech. Ageing Dev. 79:1995;1-32.
32. Pawelec G., Adibzadeh M., Pohla H., Schaudt K. Immunosenescence: Ageing of the immune system. Immunol. Today. 16:1995;420-422.
33. Sansoni P., Cossa Rizza A., Brianti V., Fagnoni F., Snelli G., Monti D., Marcato A., Passeri G., Ortolani C., Forti E.et al. Lymphocyte subsets and natural killer cell activity in healthy old people and centenarians. Blood. 82:1993;2767-2773.
34. Saransaari P., Oka S.S. Age related changes in the uptake and release of glutamate and aspartate in the mouse brain. Mech. Ageing Dev. 81:1995;61-71.
35. Solana R., Villanueva J.L., Peña J., De la Fuente M. Cell mediated immunity in ageing. Comp. Biochem. Physiol. 99A:1991;1-4.
36. Springer T.A. Adhesion receptors on the immune system. Nature. 346:1990;425-433.
37. Stein-Behrens B.A., Sapolsky R.M. Stress, glucocorticoids, and aging. Aging Clin. Exp. Res. 4:1992;197-210.
38. Walford, R.L., 1969. The Immunological Theory of Aging, Munksgaard, Copenhagen, pp. 1-248.
39. Zhang L., Kokkonen G., Roth G.S. Identification of programmed cell death in situ in the striatum of normal adult rat brain and its relationship to neuronal death during aging. Brain Res. 677:1995;177-179.