Changes with aging, sex and physical exercise in murine natural killer activity and antibody-dependent cellular cytotoxicity

Mechanisms of Ageing and Development

Volumn 86, Issue 2, 1996, Pages 83-94

  Ferrandez M D ^a   De La Fuente, M ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

Aging; Antibody dependent cellular cytotoxicity; Exercise; Mice; Natural killer; Sex

Indexed keywords

AGED; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY; ARTICLE; AXILLARY LYMPH NODE; CONTROLLED STUDY; EXERCISE; FEMALE; LEUKOCYTE; MALE; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; SEX DIFFERENCE; SPLEEN; SWIMMING; THYMUS;

ANIMALIA; MURINAE;

EID: 13344282054     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/0047-6374(95)01679-1     Document Type: Article

References (73)

1. G. Berke, Functions and mechanisms of lysis induced by cytotoxic T lymphocytes and natural killer cells. In W.E. Paul (ed.), Fundamental Immunology, Raven Press, New York, 1989, pp. 735-764.
2. G. Trinchieri, Biology of natural killer cells. Adv. Immunol., 47 (1989) 201-376.
3. M. De La Fuente, M.C. Alonso, R. Solana and J. Peña, Macrophage and lymphocyte antibody-dependent cellular cytotoxicity in spontaneous leukemogenesis of AKR/J mice. Tumor Biol., 10 (1989) 310-315.
4. A.K. Tripathi, M. Taplits, J. Puri and T. Hoffman, Augmentation of monocyte-mediated antibody-dependent cellular cytotoxicity by protein synthesis inhibitor: evidence for an endogenous regulatory mechanisms. Cell. Immunol., 134 (1991) 491-504.
5. M.W. Fanger, L. Shen, R.F. Graziano and P.M. Guyre, Cytotoxicity mediated by human Fc receptors for IgG. Immunol. Today, 10 (1989) 92-99.
6. R.L. Walford, The Immunological Theory of Aging, Munksgaard, Copenhagen, 1969, pp. 1-248.
7. G.B. Price and T. Makinodan, Immunologic deficiencies in senescence. I. Characterization of intrinsic deficiencies. J. Immunol., 108 (1972) 403.
8. T. Makinodan and M.M.B. Kay, Age influence on the immune system. Adv. Immunol., 29 (1980) 287.
9. D. Segre, R.A. Miller, G.N. Abraham, W.O. Weigle and H.R. Warner, Aging and the immune system. J. Gerontol., 44 (1989) B164-168.
10. M.E. Weksler, Protecting the aging immune system to prolong quality of life. Geriatrics, 45 (1990) 75-76.
11. R. Solana, J.L. Villanueva, J. Peña and M. De La Fuente, Cell mediated immunity in ageing. Comp. Biochem. Physiol., 99A (1991) 1-4.
12. E. Ortega, M.A. Forner, C. Barriga and M. De La Fuente, Effect of age and of swimming-induced stress on the phagocytic capacity of peritoneal macrophages from mice. Mech. Ageing Dev., 70 (1993b) 53-63.
13. G. Pawelec, Molecular and cell biological studies of ageing and their application to considerations of T lymphocyte immunosenescence. Mech. Ageing Dev ., 79 (1995) 1-32.
14. E. Ortega, M. Galan, M. De La Fuente and C. Barriga, Influence of physical activity stress and age on the ADCC of lymphocytes from mice. Arch. Gerontol. Geriatr., 16 (1993c) 93-101.
15. L.T. Mackinnon and T.B. Tomasi, Immunology of exercise. Ann. Sports Med., 3 (1986) 1-4.
16. B.K. Pedersen, Influence of physical activity on the cellular immune system: mechanisms of action. Int. J. Sports Med., 12 (1991) 23-29.
17. B.K. Pedersen, Exercise and Immunity - Mechanisms of action. Med. Sports Sci., 37 (1992) 33-39.
18. B.K. Pedersen, N. Tvede, F.R. Hansen, V. Andersen, T. Bendix, G. Bendixen, K. Bendtzen, H. Galbo, P.M. Haahr, K. Klarlund, J. Sylvest, B.S. Thomson and J. Halkjoer-Kristensen, Modulation of natural killer cell activity in peripheral blood by physical exercise. Scand. J. Immunol., 27 (1988) 673-678.
19. B.K. Pedersen, N. Tvede, L.D. Christensen, K. Klarlund, S. Kragbak and J. Halkjoer-Kristensen, Natural killer cell activity in peripheral blood of highly trained and untrained persons. Int. J. Sports Med., 10 (1989) 129-131.
20. B.T. Pedersen and H. Ullum, NK cell response to physical activity: possible mechanisms of action. Med. Sci. Sports Exerc., 26 (1994) 140-146.
21. L. Hoffman-Goetz and B.K. Pedersen Exercise and the immune response: a model of the stress response? Immunol. Today, 15 (1994) 382-387.
22. L. Fitzgerald L. Exercise and the immune system. Immunol. Today, 9 (1988) 337-339.
23. L. Fitzgerald Overtraining increases the susceptibility to infection. Int. J. Sports Med., 12 (1991) S5-S8.
24. D. Keast, K. Cameron and A.R. Morton, Exercise and the immune response. Sports Med., 5 (1988) 248-267.
25. M. Fiatarone, J. Morley, E. Bloom, D. Benton and T. Makinodan, Endogenous opioids and the exercise-induced augmentation of natural killer cell activity. J. Lab. Clin. Med., 112 (1988) 544-552.
26. M. Fiatarone, J. Morley, E. Bloom, D. Benton, G. Solomon and T. Makinodan, The effect of exercise on natural cell activity in young and old subjects. J. Gerontol., 44 (1989) 37-45.
27. D. Crist, L. Mackinnon, R. Thompson and H. Atterbom, Physical exercise increases natural cellular mediated tumor cytotoxicity in elderly women. Gerontology, 35 (1989) 66-71.
28. C.J. Grossman, Interactions between the gonadal steroids and the immune system. Science, 227 (1985) 257-261.
29. Z.M. Sthoeger, N. Chiorazzi and R.G. Lahita, Regulation of the immune response by sex hormones I: in vitro effects of stradiol and testosterone an pokeweed mitogen-induced human B cell differentiation. J. Immunol., 141 (1988) 91-98.
30. A.H. Schuurs and A.H. Verheul, Effects of gender and sex steroids on the immune response. J. Steroid Biochem., 35 (1990) 157-172.
31. B.H. Athreya, F. Pletcher, F. Zulian, D.B. Weiner and W.V. Williams, Subset-specific effects of sex hormones and pituitary gonadotropins on human lymphocyte proliferation in vitro. Clin. Immunol. Immunopathol., 66 (1993) 201-211.
32. W.P. Benten, F. Wunderlich, R. Herrman and W.N. Kuhn-Velten, Testosterone-induced compared with oestradiol-induced immunosuppresion against Plasmodium chabaudi malaria. J. Endocrinol., 139 (1993) 487-494.
33. C.J. Grossman, Regulation of the immune system by sex steroids. Endocrine Rev., 5 (1984) 435-455.
34. T.R. Cupps and A.S. Fauci, Corticosteroid-mediated immunoregulation in man. Immunol. Rev., 65 (1982) 133-155.
35. A. Munck, P.M. Guyre and N.J. Holbrook, Physiological functions of glucocorticoids in stress and their relation to pharmacological actions. Endocrine Rev., 5 (1984) 25-44.
36. E.M. Sternberg and C.W. Parker, Pharmacologic aspects of lymphocyte regulation. In J.J. Marchalonis (ed), The Lymphocyte: Structure and Function, Marcel Dekker, New York, 1988, pp. 1-54.
37. E.M. Sternberg, G.P. Chrousos, R.L. Wilder and P.W. Gold, The stress response and the regulation of inflammatory disease. Ann. Intern. Med., 117 (1992) 854-866.
38. K.S. Madden and D.L. Felten, Experimental basis for neural-immune interactions. Physiol. Rev., 75 (1995) 77-106.
39. B.F. Haynes, P. Katz and A.S. Fauci, Mechanisms of corticosteroids action on lymphocyte subpopulations.V. Effects of in vivo hydrocortisone on the circulatory kinetics and function of naturally occurring and mitogen-induced suppressor cell in man. Cell. Immunol., 44 (1979) 169-178.
40. J.E. Parrillo and A.S. Fauci, Comparison of the effector cells in human spontaneous cellular cytotoxicity and antibody-dependent cellular cytotoxicity. Differential sensivity of effector cells to in vivo and in vitro corticosteroids. Scand. J. Immunol., 8 (1978) 99-107.
41. P. Katz, A.M. Zaytoren and J.M. Lee, The effect of in vivo hydrocortisone on lymphocyte-mediated cytotoxicity. Arthritis Rheum., 27 (1984) 72-78.
42. D.M. Callewaert, V.K. Moudgil, G. Radcliff and R. Waite, Hormone specific regulation of natural killer cells by cortisol. Direct inactivation of the cytotoxic function of cloned human NK cells without and effect on cellular proliferation. FEBS Lett., 1 (1991) 108-110.
43. G. Gatti, R.G. Masera, L. Pallavicini, M.L. Sartori, A. Staurenghi, F. Orlandi and A. Angeli, Interplay in vitro between ACTH, β-endorphin, and glucocorticoids in the modulation of spontaneous and lymphokine-inducible human natural killer (NK) cell activity. Brain, Behavior, and Immunity, 7 (1993) 16-28.
44. A. Boyum, Separation of leucocytes from blood and bone marrow. Scand. J. Clin. Lab. Invest., 21 (1968) 77-82.
45. M. De la Fuente, M. Del Rio and A. Hernanz, Stimulation of natural killer and antibody-dependent cellular cytotoxicity activities in mouse leukocytes by bombesin, gastrin-releasing peptide and neuromedin C: involvement of cyclic AMP, inositol 1,4,5-trisphosphate and protein kinase C. J. Neuroimmunol., 48 (1993) 143-150.
46. J.M. Greenberg and M. Takasugi, In R.B. Heberman (ed.), Natural Cell-mediated Immunity Against Tumors, Academic Press, 1980, New York, pp. 835.
47. M. De La Fuente, Changes in the macrophage function with aging. Camp. Biochem. Physiol., 81A (1985) 935-938.
48. L. Lhotellier and C. Cohen-Salmon, Senescence of moto-behavior in mice. Contributions of genetics methods. Env. Bull. Cognitive Physiol., 11 (1991) 27-53.
49. T. Makinodan, T.J. Hahn, S. McDougall, D.T. Yamaguchi, M. Fang and A. Iida-Klein, Cellular immunosenescence: an overview. Exp. Gerontol., 26 (1991). 281-288.
50. M. De la Fuente, M.D. Ferrández, J. Miquel and A. Hernanz, Changes with aging and physical exercise in ascorbic acid content and proliferative response of murine lymphocytes. Mech. Ageing Dev., 65 (1992) 177-186.
51. M. De la Fuente, M.D. Ferrández, F. Muñoz, E. De Juan and J. Miquel, Stimulation by the antioxidant thioproline of the lymphocyte functions of old mice. Mech. Ageing Dev., 68 (1993) 27-36.
52. E. Ortega, C. Barriga and M. De La Fuente, Aging and the non-specific immune response. Facts Res. Gerontol., 7 (1993a) 23-29.
53. J. Penschow and I.R. Mackay, Nk and K cell activity of human blood: differences according to sex, age and disease. Ann. Rheum. Dis., 39 (1980) 82.
54. R.K. Saxena, Q.B. Saxena and W.H. Adler, Interleukin-2-induced activation of natural killer activity in spleen cells from young and old mice. Immunology, 51 (1984) 719.
55. D. Davila and K. Kelley, Sex differences in lectin-induced interleukin-2. Synthesis in aging rats. Mech. Ageing Dev., 44 (1988) 231.
56. A. Facchini, E. Mariani, A.R. Mariani, S. Papa, M. Vitali and F.A. Manzoli, Increase number of circulating Leu 11 + (CD16) large granular lymphocytes and decreased NK activity during human ageing. Clin. Exp. Immunol., 68 (1987) 82.
57. P. Sansoni, A. Cossa Rizza, V. Brianti, F. Fagnoni, G. Snelli, D. Monti, A. Marcato, G. Passeri, C. Ortolani, E. Forti, et al., Lymphocyte subsets and natural killer cell activity in healthy old people and centenarians. Blood, 82 (1993) 2767-2773.
58. E. Hedfors, G. Holm and B. Öhnell, Variations of blood lymphocytes during work studied by cell surface markers, DNA synthesis and cytotoxicity. Clin. Exp. Immunol., 24 (1976) 328-335.
59. P.G. Hanson and D.K. Flaherty, Immunological responses to training in conditioned runners. Clin. Sci., 60 (1981) 225-228.
60. D.C. Nieman, S.L. Nehlsen-Cannarella, K.M. Donohue, D.B.W. Chritton, B.L. Haddock, R.W. Stout and J.W. Lee, The effects of acute moderate exercise on leukocyte and lymphocyte subpopulations. Med. Sci. Sports Exerc., 23 (1990) 578-585.
61. D.C. Nieman, A.R. Miller, D.A. Henson, B.J. Warren, G. Gusewitch, R.L. Johnson, J.M. Davis, D.E. Butterworth and S.L. Nehlsen-Cannarella, Effects of high- vs moderate-intensity exercise on natural killer cell activity. Med. Sci. Sports Exercise, 25 (1993a) 1126-1134.
62. D.C. Nieman, D.A. Henson, G. Gusewitch, B.J. Warren, R.C. Dotson, D.E. Butterworth and S.L. Nehlsen-Cannarella, Physical activity and immune function in elderly women. Med. Sci. Sports Exercise, 25 (1993b) 823-831.
63. B. McNeil and L. Hoffman-Goezt, Effect of exercise on natural cytotoxicity and pulmonary tumor metastases in mice. Med. Sci. Sports Exercise, 25 (1993) 922-928.
64. D.C. Nieman and S.L. Nehlsen-Cannarella, The immune response to exercise. Semin. Hematol., 31 (1994) 166-179.
65. D.C. Nieman, Exercise, upper respiratory tract infection, and the immune system. Med. Sci. Sports Exercise, 26 (1994) 128-139.
66. Z. Brahmi, J.E. Thomas, M. Park, M. Park and I.R.G. Dowdeswell, The effect of acute exercise on natural killer-cell activity of trained and sedentary human subjects. J. Clin. Immunol., 5 (1985) 321-328.
67. R. Dantzer and K. Kelley, Stress and immunity: an integrated view of relationship between the brain and the immune system. Life Sci., 44 (1989) 1995-2008.
68. J.I. Kitay, Sex differences in adrenal cortical secretion in the rat. Endocrinology, 68 (1961) 818-824.
69. J. Dunn, L. Scheving and P. Millet, Circadian variation in stress-evoked increases in plasma corticosterone. Am. J. Physiol., 223 (1972) 402-406.
70. J.C. Le Mavel, S. Abitbol, G. Beraud and J. Maniey, Temporal changes in plasma adrenocorticotropin concentrations after repeated neurotropic stress in male and female rats. Endocrinology, 105 (1979) 812-817.
71. G.J. Kant, R.H. Lenox, B.N. Bunnell, E.H. Mougey, L.L. Pennington and J.L. Meyerhoff, Comparison of stress response in male and female rats: pituitary cyclic AMP and plasma prolactin, growth hormone and corticosterone. Psychoneuroendocrinology, 8 (1983) 421-428.
72. G.T. Livezey, J.M. Miller and W.H. Vogel, Plasma norepinephrine, epinephrine and corticosterone stress responses to restraint in individual male and female rats, and their correlations. Neurosci. Lett., 62 (1985) 51-56.
73. R.P.W. Heinsbroek, F. Van Haaren, M.G.P. Feenstra, H. Van Galen, G. Boer and N.E. Van De Poll, Sex differences in the effects of inescapable footshock on central catecholaminergic and serotonergic activity. Pharmacol. Biochem. Behav., 37 (1990) 539-550.