-
1
-
-
0025959101
-
An updated coronary risk profile. A statement for health professionals
-
Anderson KM, Wilson PW, Odell PM, Kannel WB. An updated coronary risk profile. A statement for health professionals. Circulation. 1991;83:356-362.
-
(1991)
Circulation
, vol.83
, pp. 356-362
-
-
Anderson, K.M.1
Wilson, P.W.2
Odell, P.M.3
Kannel, W.B.4
-
2
-
-
0021350001
-
The Lipid Research Clinics Coronary Primary Prevention Trial results. 1. Reduction in incidence of coronary heart disease
-
The Lipid Research Clinics Coronary Primary Prevention Trial results. 1. Reduction in incidence of coronary heart disease. JAMA. 1984;251:351-364.
-
(1984)
JAMA
, vol.251
, pp. 351-364
-
-
-
3
-
-
0021349709
-
The Lipid Research Clinics Coronary Primary Prevention Trial results. II. The relationship of reduction in the incidence of coronary heart disease to cholesterol lowering
-
The Lipid Research Clinics Coronary Primary Prevention Trial results. II. The relationship of reduction in the incidence of coronary heart disease to cholesterol lowering. JAMA. 1984;251:365-374.
-
(1984)
JAMA
, vol.251
, pp. 365-374
-
-
-
4
-
-
0027987849
-
Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4S)
-
Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4S). Lancet. 1994;344:1383-1389.
-
(1994)
Lancet
, vol.344
, pp. 1383-1389
-
-
-
5
-
-
0342981862
-
The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels
-
Cholesterol and Recurrent Events Trial Investigators
-
Sacks FM, Pfeffer MA, Moye LA, et al. The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events Trial Investigators. N Engl J Med. 1996;335:1001-1009.
-
(1996)
N Engl J Med
, vol.335
, pp. 1001-1009
-
-
Sacks, F.M.1
Pfeffer, M.A.2
Moye, L.A.3
-
6
-
-
0032487931
-
Prevention of cardiovascular events and deaths with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels
-
The Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study Group
-
Prevention of cardiovascular events and deaths with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. The Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study Group. N Engl J Med. 1998;339:1349-1357.
-
(1998)
N Engl J Med
, vol.339
, pp. 1349-1357
-
-
-
7
-
-
0032572086
-
Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: Results of AFCAPS/TexCAPS. Air Force/Texas Coronary Atherosclerosis Prevention Study
-
Downs JR, Clearfield M, Weis S, et al. Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: Results of AFCAPS/TexCAPS. Air Force/Texas Coronary Atherosclerosis Prevention Study. JAMA. 1998;279:1615-1622.
-
(1998)
JAMA
, vol.279
, pp. 1615-1622
-
-
Downs, J.R.1
Clearfield, M.2
Weis, S.3
-
8
-
-
0028883828
-
Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia
-
Shepherd J, Cobbe SM, Ford I, et al. Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. N Engl J Med. 1995;333:1301-1307.
-
(1995)
N Engl J Med
, vol.333
, pp. 1301-1307
-
-
Shepherd, J.1
Cobbe, S.M.2
Ford, I.3
-
9
-
-
0035897696
-
Expert Panel of Detection, Evaluation and Treatment of High Blood Cholesterol in Adults: Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
-
Expert Panel of Detection, Evaluation and Treatment of High Blood Cholesterol in Adults: Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA. 2001;285:2486-2497.
-
(2001)
JAMA
, vol.285
, pp. 2486-2497
-
-
-
10
-
-
0031939253
-
European and American recommendations for coronary heart disease prevention
-
Wood D. European and American recommendations for coronary heart disease prevention. Eur Heart J. 1998;19(Suppl A):A12-A19.
-
(1998)
Eur Heart J
, vol.19
, Issue.SUPPL. A
-
-
Wood, D.1
-
12
-
-
0028096810
-
A review of clinical trials comparing HMG-CoA reductase inhibitors
-
Illingworth DR, Tobert JA. A review of clinical trials comparing HMG-CoA reductase inhibitors. Clin Ther. 1994;16:366-385.
-
(1994)
Clin Ther
, vol.16
, pp. 366-385
-
-
Illingworth, D.R.1
Tobert, J.A.2
-
13
-
-
0032554671
-
Statin trials and goals of cholesterol-lowering therapy
-
Grundy SM. Statin trials and goals of cholesterol-lowering therapy. Circulation. 1998;97:1436-1439.
-
(1998)
Circulation
, vol.97
, pp. 1436-1439
-
-
Grundy, S.M.1
-
14
-
-
0029101804
-
Comparative evaluation of the safety and efficacy of HMG-CoA reductase inhibitor monotherapy in the treatment of primary hypercholesterolemia
-
Hsu I, Spinler SA, Johnson NE. Comparative evaluation of the safety and efficacy of HMG-CoA reductase inhibitor monotherapy in the treatment of primary hypercholesterolemia. Ann Pharmacother. 1995;29:743-759.
-
(1995)
Ann Pharmacother
, vol.29
, pp. 743-759
-
-
Hsu, I.1
Spinler, S.A.2
Johnson, N.E.3
-
15
-
-
0035197395
-
Statin myopathies: Pathophysiologic and clinical perspectives
-
Baker SK, Tarnopolsky MA. Statin myopathies: Pathophysiologic and clinical perspectives. Clin Invest Med. 2001;24:258-272.
-
(2001)
Clin Invest Med
, vol.24
, pp. 258-272
-
-
Baker, S.K.1
Tarnopolsky, M.A.2
-
16
-
-
0343081551
-
Policosanol
-
Más R. Policosanol. Drugs of the Future. 2000;25:569-586.
-
(2000)
Drugs of the Future
, vol.25
, pp. 569-586
-
-
Más, R.1
-
17
-
-
0028227198
-
Effects of successive dose increases of policosanol on the lipid profile of patients with type II hypercholesterolaemia and tolerability to treatment
-
Pons P, Rodriguez M, Robaina C, et al. Effects of successive dose increases of policosanol on the lipid profile of patients with type II hypercholesterolaemia and tolerability to treatment. Int J Clin Pharmacol Res. 1994;14:27-33.
-
(1994)
Int J Clin Pharmacol Res
, vol.14
, pp. 27-33
-
-
Pons, P.1
Rodriguez, M.2
Robaina, C.3
-
18
-
-
0029589212
-
A two-year study on the efficacy and tolerability of policosanol in patients with type II hyperlipoproteinaemia
-
Canetti M, Moreira M, Más R, et al. A two-year study on the efficacy and tolerability of policosanol in patients with type II hyperlipoproteinaemia. Int J Clin Pharmacol Res. 1995;15:159-165.
-
(1995)
Int J Clin Pharmacol Res
, vol.15
, pp. 159-165
-
-
Canetti, M.1
Moreira, M.2
Más, R.3
-
19
-
-
0031406593
-
A comparative study of policosanol versus pravastatin in patients with type II hypercholesterolemia
-
Benitez M, Romero C, Más R, et al. A comparative study of policosanol versus pravastatin in patients with type II hypercholesterolemia. Curr Ther Res Clin Exp. 1997;58:859-867.
-
(1997)
Curr Ther Res Clin Exp
, vol.58
, pp. 859-867
-
-
Benitez, M.1
Romero, C.2
Más, R.3
-
20
-
-
0032970949
-
Effects of policosanol in patients with type II hypercholesterolemia and additional coronary risk factors
-
Más R, Castaño G, Illnait J, et al. Effects of policosanol in patients with type II hypercholesterolemia and additional coronary risk factors. Clin Pharmacol Ther. 1999;65:439-447.
-
(1999)
Clin Pharmacol Ther
, vol.65
, pp. 439-447
-
-
Más, R.1
Castaño, G.2
Illnait, J.3
-
21
-
-
0033936923
-
Effect of policosanol on postmenopausal women with type II hypercholesterolemia
-
Castaño G, Más R, Fernández L, et al. Effect of policosanol on postmenopausal women with type II hypercholesterolemia. Gynecol Endocrinol. 2000;14:187-195.
-
(2000)
Gynecol Endocrinol
, vol.14
, pp. 187-195
-
-
Castaño, G.1
Más, R.2
Fernández, L.3
-
22
-
-
0343526455
-
Effects of policosanol and pravastatin on lipid profile, platelet aggregation and endothelemia in older hypercholesterolemic patients
-
Castaño G, Más R, Arruzazabala ML, et al. Effects of policosanol and pravastatin on lipid profile, platelet aggregation and endothelemia in older hypercholesterolemic patients. Int J Clin Pharm Res. 1999;19:105-116.
-
(1999)
Int J Clin Pharm Res
, vol.19
, pp. 105-116
-
-
Castaño, G.1
Más, R.2
Arruzazabala, M.L.3
-
23
-
-
0035116259
-
Effects of policosanol in older patients with type II hypercholesterolemia and high coronary risk
-
Castaño G, Más R, Fernández JC, et al. Effects of policosanol in older patients with type II hypercholesterolemia and high coronary risk. J Gerontol A Biol Sci Med Sci. 2001;56:M186-M192.
-
(2001)
J Gerontol A Biol Sci Med Sci
, vol.56
-
-
Castaño, G.1
Más, R.2
Fernández, J.C.3
-
24
-
-
0035092189
-
Comparison of the efficacy, safety and tolerability of policosanol versus fluvastatin in elderly hypercholesterolemic women
-
Fernández JC, Más R, Castaño G, et al. Comparison of the efficacy, safety and tolerability of policosanol versus fluvastatin in elderly hypercholesterolemic women. Clin Drug Invest. 2001;21:103-113.
-
(2001)
Clin Drug Invest
, vol.21
, pp. 103-113
-
-
Fernández, J.C.1
Más, R.2
Castaño, G.3
-
25
-
-
0034913131
-
Effects of policosanol in older hypercholesterolemic patients with coronary disease
-
Más R, Castaño G, Fernández L, et al. Effects of policosanol in older hypercholesterolemic patients with coronary disease. Clin Drug Invest. 2001;21:485-497.
-
(2001)
Clin Drug Invest
, vol.21
, pp. 485-497
-
-
Más, R.1
Castaño, G.2
Fernández, L.3
-
26
-
-
0028897637
-
Treatment of hypercholesterolemia in NIDDM with policosanol
-
Torres O, Agramonte AJ, Illnait J, et al. Treatment of hypercholesterolemia in NIDDM with policosanol. Diabetes Care. 1995;18:393-397.
-
(1995)
Diabetes Care
, vol.18
, pp. 393-397
-
-
Torres, O.1
Agramonte, A.J.2
Illnait, J.3
-
27
-
-
0033358535
-
Comparative study of the efficacy and tolerability of policosanol and lovastatin in patients with hypercholesterolemia and noninsulin dependent diabetes mellitus
-
Crespo N, Illnait J, Más R, et al. Comparative study of the efficacy and tolerability of policosanol and lovastatin in patients with hypercholesterolemia and noninsulin dependent diabetes mellitus. Int J Clin Pharmacol Res. 1999;19:117-127.
-
(1999)
Int J Clin Pharmacol Res
, vol.19
, pp. 117-127
-
-
Crespo, N.1
Illnait, J.2
Más, R.3
-
28
-
-
0028568193
-
Policosanol inhibits cholesterol biosynthesis and enhances low density lipoprotein processing in cultured human fibroblasts
-
Menéndez R, Fernández SI, Del Rio A, et al. Policosanol inhibits cholesterol biosynthesis and enhances low density lipoprotein processing in cultured human fibroblasts. Biol Res. 1994;27:199-203.
-
(1994)
Biol Res
, vol.27
, pp. 199-203
-
-
Menéndez, R.1
Fernández, S.I.2
Del Rio, A.3
-
29
-
-
0343052967
-
Cholesterol-lowering effect of policosanol on rabbits with hypercholesterolaemia induced by a wheat starch-casein diet
-
Menéndez R, Arruzazabala ML, Más R, et al. Cholesterol-lowering effect of policosanol on rabbits with hypercholesterolaemia induced by a wheat starch-casein diet. Br J Nutr. 1996;77:923-932.
-
(1996)
Br J Nutr
, vol.77
, pp. 923-932
-
-
Menéndez, R.1
Arruzazabala, M.L.2
Más, R.3
-
30
-
-
0035098624
-
Policosanol modulates HMG-CoA reductase activity in cultured fibroblasts
-
Menéndez R, Amor AM, Rodeiro I, et al. Policosanol modulates HMG-CoA reductase activity in cultured fibroblasts. Arch Med Res. 2001;32:8-12.
-
(2001)
Arch Med Res
, vol.32
, pp. 8-12
-
-
Menéndez, R.1
Amor, A.M.2
Rodeiro, I.3
-
31
-
-
0031729810
-
Policosanol: Results of a postmarketing surveillance study of 27,879 patients
-
Fernández L, Más R, Illnait J, Fernandez JC. Policosanol: Results of a postmarketing surveillance study of 27,879 patients. Curr Ther Res Clin Exp. 1998;59:717-722.
-
(1998)
Curr Ther Res Clin Exp
, vol.59
, pp. 717-722
-
-
Fernández, L.1
Más, R.2
Illnait, J.3
Fernandez, J.C.4
-
33
-
-
0030043107
-
Drug therapy for hypercholesterolemia in patients with cardiovascular disease: Factors limiting achievement of lipid goals
-
Schectman G, Hiatt J. Drug therapy for hypercholesterolemia in patients with cardiovascular disease: Factors limiting achievement of lipid goals. Am J Med. 1996;100:197-204.
-
(1996)
Am J Med
, vol.100
, pp. 197-204
-
-
Schectman, G.1
Hiatt, J.2
-
34
-
-
0019488877
-
Separation of serum high-density lipoprotein for cholesterol determination: Ultracentrifugation vs precipitation with sodium phosphotungstate and magnesium chloride
-
Seigler L, Wu WT. Separation of serum high-density lipoprotein for cholesterol determination: Ultracentrifugation vs precipitation with sodium phosphotungstate and magnesium chloride. Clin Chem. 1981;27:838-841.
-
(1981)
Clin Chem
, vol.27
, pp. 838-841
-
-
Seigler, L.1
Wu, W.T.2
-
35
-
-
0015348189
-
Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge
-
Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem. 1972;18:499-502.
-
(1972)
Clin Chem
, vol.18
, pp. 499-502
-
-
Friedewald, W.T.1
Levy, R.I.2
Fredrickson, D.S.3
-
36
-
-
0033044791
-
Cost of treating to a modified European Atheroesclerosis Society LDL-C Target. Comparison of atorvastatin with fluvastatin, pravastatin and simvastatin
-
Smith DG, Leslie SJ, Szucs TD, et al. Cost of treating to a modified European Atheroesclerosis Society LDL-C Target. Comparison of atorvastatin with fluvastatin, pravastatin and simvastatin. Clin Drug Invest. 1999;17:185-193.
-
(1999)
Clin Drug Invest
, vol.17
, pp. 185-193
-
-
Smith, D.G.1
Leslie, S.J.2
Szucs, T.D.3
-
37
-
-
0027413130
-
Effects of Policosanol on platelet aggregation in rats
-
Arruzazabala ML, Carbajal D, Más R, et al. Effects of Policosanol on platelet aggregation in rats. Thromb Res. 1993;69:321-327.
-
(1993)
Thromb Res
, vol.69
, pp. 321-327
-
-
Arruzazabala, M.L.1
Carbajal, D.2
Más, R.3
-
38
-
-
0027183580
-
Effect of policosanol on cerebral ischemia in Mongolian gerbils: Role of prostacyclin and thromboxane A2
-
Arruzazabala ML, Molina V, Carbajal D, et al. Effect of policosanol on cerebral ischemia in Mongolian gerbils: Role of prostacyclin and thromboxane A2. Prostaglandins Leukot Essent Fatty Acids. 1993;49:695-697.
-
(1993)
Prostaglandins Leukot Essent Fatty Acids
, vol.49
, pp. 695-697
-
-
Arruzazabala, M.L.1
Molina, V.2
Carbajal, D.3
-
40
-
-
0030295032
-
Effect of policosanol successive dose increases on platelet aggregation in healthy volunteers
-
Arruzazabala ML, Valdes S, Más R, et al. Effect of policosanol successive dose increases on platelet aggregation in healthy volunteers. Pharmacol Res. 1996;34:181-185.
-
(1996)
Pharmacol Res
, vol.34
, pp. 181-185
-
-
Arruzazabala, M.L.1
Valdes, S.2
Más, R.3
-
41
-
-
0031257654
-
Comparative study of policosanol, aspirin and the combination therapy policosanol-aspirin on platelet aggregation in healthy volunteers
-
Arruzazabala ML, Valdes S, Más R, et al. Comparative study of policosanol, aspirin and the combination therapy policosanol-aspirin on platelet aggregation in healthy volunteers. Pharmacol Res. 1997;36:293-297.
-
(1997)
Pharmacol Res
, vol.36
, pp. 293-297
-
-
Arruzazabala, M.L.1
Valdes, S.2
Más, R.3
-
42
-
-
0032145343
-
Interaction policosanol-warfarin on bleeding time and thrombosis in rats
-
Carbajal D, Arruzazabala ML, Valdes S, Más R. Interaction policosanol-warfarin on bleeding time and thrombosis in rats. Pharmacol Res. 1998;38:89-91.
-
(1998)
Pharmacol Res
, vol.38
, pp. 89-91
-
-
Carbajal, D.1
Arruzazabala, M.L.2
Valdes, S.3
Más, R.4
-
43
-
-
0032467742
-
Effect of policosanol on platelet aggregation in type 11 hypercholesterolemic patients
-
Arruzazabala ML, Más R, Molina V, et al. Effect of policosanol on platelet aggregation in type 11 hypercholesterolemic patients. Int J Tissue React. 1998;20:119-124.
-
(1998)
Int J Tissue React
, vol.20
, pp. 119-124
-
-
Arruzazabala, M.L.1
Más, R.2
Molina, V.3
-
44
-
-
0142074299
-
Comparison of the effects of policosanol and atorvastatin on lipid profile and platelet aggregation on patients with dyslipidemia and type 2 diabetes mellitus
-
In press
-
Castaño G, Fernández L, Más R, et al. Comparison of the effects of policosanol and atorvastatin on lipid profile and platelet aggregation on patients with dyslipidemia and type 2 diabetes mellitus. Clin Drug Invest. 2003. In press.
-
(2003)
Clin Drug Invest
-
-
Castaño, G.1
Fernández, L.2
Más, R.3
-
45
-
-
0033813254
-
Effects of policosanol treatment on the susceptibility of low density lipoprotein (LDL) isolated from healthy volunteers to oxidative modification in vitro
-
Menéndez R, Más R, Amor AM, et al. Effects of policosanol treatment on the susceptibility of low density lipoprotein (LDL) isolated from healthy volunteers to oxidative modification in vitro. Br J Clin Pharmacol. 2000;50:255-262.
-
(2000)
Br J Clin Pharmacol
, vol.50
, pp. 255-262
-
-
Menéndez, R.1
Más, R.2
Amor, A.M.3
-
46
-
-
0033823403
-
Effects of policosanol on the susceptibility of low-density lipoprotein isolated from hypercholesterolemic patients at high coronary risk to in vitro copper-mediated lipid peroxidation: A randomized, double-blind pilot study
-
Menéndez R, Más R, Amor AM, et al. Effects of policosanol on the susceptibility of low-density lipoprotein isolated from hypercholesterolemic patients at high coronary risk to in vitro copper-mediated lipid peroxidation: A randomized, double-blind pilot study. Curr Ther Res Clin Exp. 2000;61:609-620.
-
(2000)
Curr Ther Res Clin Exp
, vol.61
, pp. 609-620
-
-
Menéndez, R.1
Más, R.2
Amor, A.M.3
-
47
-
-
24544474161
-
Effects of policosanol (5-10 mg/day) in older hypercholesterolemic patients
-
Number 9. Abstract
-
Más R, Castaño G, Fernández J, et al. Effects of policosanol (5-10 mg/day) in older hypercholesterolemic patients. J Am Coll Cardiol. 2002;39(Suppl B):Number 9. Abstract.
-
(2002)
J Am Coll Cardiol
, vol.39
, Issue.SUPPL. B
-
-
Más, R.1
Castaño, G.2
Fernández, J.3
-
48
-
-
0031923069
-
Effect of policosanol on arterial blood pressure in rats. Study of the pharmacological interaction with nifedipine and propranolol
-
Molina Cuevas V, Arruzazabala ML, Carbajal Quintana D, et al. Effect of policosanol on arterial blood pressure in rats. Study of the pharmacological interaction with nifedipine and propranolol. Arch Med Res. 1998;29:21-24.
-
(1998)
Arch Med Res
, vol.29
, pp. 21-24
-
-
Molina Cuevas, V.1
Arruzazabala, M.L.2
Carbajal Quintana, D.3
|