-
1
-
-
0027459198
-
mdm2 expression is induced by wild type p53 activity
-
Barak Y, Juven T, Haffner R, Oren M. mdm2 expression is induced by wild type p53 activity. EMBO J 1993;12:461-8.
-
(1993)
EMBO J
, vol.12
, pp. 461-468
-
-
Barak, Y.1
Juven, T.2
Haffner, R.3
Oren, M.4
-
2
-
-
0026523614
-
Enhanced binding of a 95 kD protein to p53 in cells undergoing p53 mediated growth arrest
-
Barak Y, Oren M. Enhanced binding of a 95 kD protein to p53 in cells undergoing p53 mediated growth arrest. EMBO J 1992;11: 2115-21.
-
(1992)
EMBO J
, vol.11
, pp. 2115-2121
-
-
Barak, Y.1
Oren, M.2
-
3
-
-
0029818380
-
Identification of novel mdm2 binding peptides by phage display
-
Böttger V, Böttger A, Howard SF, et al. Identification of novel mdm2 binding peptides by phage display. Oncogene 1996;13: 2141-7.
-
(1996)
Oncogene
, vol.13
, pp. 2141-2147
-
-
Böttger, V.1
Böttger, A.2
Howard, S.F.3
-
4
-
-
0027222956
-
Mapping of the p53 and mdm-2 interaction domains
-
Chen J, Marechal V, Levine AJ. Mapping of the p53 and mdm-2 interaction domains. Mol Cell Biol 1993;13:4107-14.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 4107-4114
-
-
Chen, J.1
Marechal, V.2
Levine, A.J.3
-
5
-
-
0029913730
-
mdm2 inhibits the G1 arrest and apoptosis functions of the p53 tumor suppressor protein
-
Chen J, Wu X, Lin J, Levine AJ. mdm2 inhibits the G1 arrest and apoptosis functions of the p53 tumor suppressor protein. Mol Cell Biol 1996;16:2445-52.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 2445-2452
-
-
Chen, J.1
Wu, X.2
Lin, J.3
Levine, A.J.4
-
6
-
-
0028098165
-
Molecular abnormalities of mdm2 and p53 genes in adult soft tissue sarcomas
-
Cordon-Cardo C, Latres E, Drobnjak M, et al. Molecular abnormalities of mdm2 and p53 genes in adult soft tissue sarcomas. Cancer Res 1994;54:794-9.
-
(1994)
Cancer Res
, vol.54
, pp. 794-799
-
-
Cordon-Cardo, C.1
Latres, E.2
Drobnjak, M.3
-
7
-
-
0031038770
-
Molecular abnormalities of the p53 pathway in dedifferentiated liposarcoma
-
Dei Tos AP, Doglioni C, Piccinin S, et al. Molecular abnormalities of the p53 pathway in dedifferentiated liposarcoma. J Pathol 1997; 181:8-13.
-
(1997)
J Pathol
, vol.181
, pp. 8-13
-
-
Dei Tos, A.P.1
Doglioni, C.2
Piccinin, S.3
-
8
-
-
0029981711
-
Tumor suppressor genes and related molecules in leiomyosarcoma
-
Dei Tos AP, Maestro R, Doglioni C, et al. Tumor suppressor genes and related molecules in leiomyosarcoma. Am J Pathol 1996;148: 1037-45.
-
(1996)
Am J Pathol
, vol.148
, pp. 1037-1045
-
-
Dei Tos, A.P.1
Maestro, R.2
Doglioni, C.3
-
9
-
-
0025853776
-
Tumorigenic potential associated with enhanced expression of a gene that is amplified in a mouse tumor cell line
-
Fakharzadeh SS, Trusko SP, George DL. Tumorigenic potential associated with enhanced expression of a gene that is amplified in a mouse tumor cell line. EMBO J 1991;10:1565-9.
-
(1991)
EMBO J
, vol.10
, pp. 1565-1569
-
-
Fakharzadeh, S.S.1
Trusko, S.P.2
George, D.L.3
-
10
-
-
0027498314
-
The mdm2 oncogene can overcome wild type p53 suppression of transformed cell growth
-
Finlay CA. The mdm2 oncogene can overcome wild type p53 suppression of transformed cell growth. Mol Cell Biol 1993;13: 301-6.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 301-306
-
-
Finlay, C.A.1
-
11
-
-
0028030882
-
MDM2 gene amplification and transcript levels in human sarcomas: Relationship to tp53 gene status
-
Florenes VA, Maelandsmo GM, Forus A, Andreassen A, Myklebost O, Fodstad O. MDM2 gene amplification and transcript levels in human sarcomas: relationship to tp53 gene status. J Natl Cancer Inst 1994;86:1297-302.
-
(1994)
J Natl Cancer Inst
, vol.86
, pp. 1297-1302
-
-
Florenes, V.A.1
Maelandsmo, G.M.2
Forus, A.3
Andreassen, A.4
Myklebost, O.5
Fodstad, O.6
-
12
-
-
0029829291
-
A molecular and immunohistochemical study of the mdm2 isoforms and p53 gene product in bronchiogenic carcinoma
-
Gorgoulis VG, Zoumpourlis V, Rassidakis GZ, et al. A molecular and immunohistochemical study of the mdm2 isoforms and p53 gene product in bronchiogenic carcinoma. J Pathol 1996;180:129-37.
-
(1996)
J Pathol
, vol.180
, pp. 129-137
-
-
Gorgoulis, V.G.1
Zoumpourlis, V.2
Rassidakis, G.Z.3
-
13
-
-
0028299342
-
P53 in tumor pathology: Can we trust immunohistochemistry? - Revisited!
-
Hall P, Lane DP. P53 in tumor pathology: can we trust immunohistochemistry? - Revisited! J Pathol 1994;172:1-4.
-
(1994)
J Pathol
, vol.172
, pp. 1-4
-
-
Hall, P.1
Lane, D.P.2
-
14
-
-
0030575937
-
Structure of the mdm2 oncoprotein bound to the p53 tumor suppressor transactivation domain
-
Kussie PH, Gorina S, Marechal V, et al. Structure of the mdm2 oncoprotein bound to the p53 tumor suppressor transactivation domain. Science 1996;274:948-53.
-
(1996)
Science
, vol.274
, pp. 948-953
-
-
Kussie, P.H.1
Gorina, S.2
Marechal, V.3
-
15
-
-
0027508958
-
MDM2 gene amplification in metastatic osteosarcoma
-
Ladanyi M, Cha C, Lewis R, Jahnwar SC, Huvos AG, Healey JA. MDM2 gene amplification in metastatic osteosarcoma. Cancer Res 1993;53:16-8.
-
(1993)
Cancer Res
, vol.53
, pp. 16-18
-
-
Ladanyi, M.1
Cha, C.2
Lewis, R.3
Jahnwar, S.C.4
Huvos, A.G.5
Healey, J.A.6
-
16
-
-
0028955652
-
MDM2 and CDK4 gene amplification in Ewing's sarcoma
-
Ladanyi M, Lewis R, Jahnwar SC, Gerald W, Huvos AG, Healey JH. MDM2 and CDK4 gene amplification in Ewing's sarcoma. J Pathol 1995;175:211-7.
-
(1995)
J Pathol
, vol.175
, pp. 211-217
-
-
Ladanyi, M.1
Lewis, R.2
Jahnwar, S.C.3
Gerald, W.4
Huvos, A.G.5
Healey, J.H.6
-
17
-
-
0027956208
-
Enhanced translation: A novel mechanism of mdm2 oncogene overexpression identified in human tumor cells
-
Landers JE, Haines DS, Straus JF, George DL. Enhanced translation: a novel mechanism of mdm2 oncogene overexpression identified in human tumor cells. Oncogene 1994;9:2745-50.
-
(1994)
Oncogene
, vol.9
, pp. 2745-2750
-
-
Landers, J.E.1
Haines, D.S.2
Straus, J.F.3
George, D.L.4
-
18
-
-
0027232042
-
p53 mutation and mdm2 amplification in human soft tissue sarcomas
-
Leach FS, Tokino T, Meltzer P, et al. p53 mutation and mdm2 amplification in human soft tissue sarcomas. Cancer Res 1993;53: 2231-4.
-
(1993)
Cancer Res
, vol.53
, pp. 2231-2234
-
-
Leach, F.S.1
Tokino, T.2
Meltzer, P.3
-
19
-
-
0028023524
-
Altered patterns of MDM2 and TP53 expression in human bladder cancer
-
Lianes P, Orlow I, Zhang ZF, et al. Altered patterns of MDM2 and TP53 expression in human bladder cancer. J Natl Cancer Inst 1994;86:1325-30.
-
(1994)
J Natl Cancer Inst
, vol.86
, pp. 1325-1330
-
-
Lianes, P.1
Orlow, I.2
Zhang, Z.F.3
-
20
-
-
0028303752
-
Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein
-
Lin J, Chen J, Elenbaas B, Levine AJ. Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein Genes Dev 1994;8:1235-46.
-
(1994)
Genes Dev
, vol.8
, pp. 1235-1246
-
-
Lin, J.1
Chen, J.2
Elenbaas, B.3
Levine, A.J.4
-
21
-
-
0029028353
-
Stimulation of E2F1/DP1 transcriptional activity by MDM2 oncoprotein
-
Martin K, Trouche D, Hagemeier C, Sorensen TS, La Thangue NB, Kouzarides T. Stimulation of E2F1/DP1 transcriptional activity by MDM2 oncoprotein. Nature 1995;375:691-4.
-
(1995)
Nature
, vol.375
, pp. 691-694
-
-
Martin, K.1
Trouche, D.2
Hagemeier, C.3
Sorensen, T.S.4
La Thangue, N.B.5
Kouzarides, T.6
-
22
-
-
0029796241
-
MDM2 amplification in a primary alveolar rhabdomyosarcoma displaying a t(2;13)(q35;q14)
-
Meddeb M, Valent A, Danglot G, et al. MDM2 amplification in a primary alveolar rhabdomyosarcoma displaying a t(2;13)(q35;q14). Cytogenet Cell Genet 1996;73:325-30.
-
(1996)
Cytogenet Cell Genet
, vol.73
, pp. 325-330
-
-
Meddeb, M.1
Valent, A.2
Danglot, G.3
-
23
-
-
0026235072
-
Identification and cloning of a novel amplified DNA sequence in human malignant fibrous histiocytoma derived from a region of chromosome 12 frequently rearranged in soft tissue tumors
-
Meltzer PS, Jankowski SA, Dal Cin P, Sandberg AA, Paz IB, Coccia MA. Identification and cloning of a novel amplified DNA sequence in human malignant fibrous histiocytoma derived from a region of chromosome 12 frequently rearranged in soft tissue tumors. Cell Growth Differ 1991;2:495-501.
-
(1991)
Cell Growth Differ
, vol.2
, pp. 495-501
-
-
Meltzer, P.S.1
Jankowski, S.A.2
Dal Cin, P.3
Sandberg, A.A.4
Paz, I.B.5
Coccia, M.A.6
-
24
-
-
0029984820
-
Analysis of the proportion of p53 bound to mdm2 in cells with defined growth characteristics
-
Momand J, Zambetti GP. Analysis of the proportion of p53 bound to mdm2 in cells with defined growth characteristics. Oncogene 1996;12:2279-89.
-
(1996)
Oncogene
, vol.12
, pp. 2279-2289
-
-
Momand, J.1
Zambetti, G.P.2
-
25
-
-
0026649648
-
The mdm2 oncogene product forms a complex with the p53 protein and inhibits p53 mediated transactivation
-
Momand J, Zambetti GP, Olson DC, George D, Levine AJ. The mdm2 oncogene product forms a complex with the p53 protein and inhibits p53 mediated transactivation. Cell 1992;69:1237-45.
-
(1992)
Cell
, vol.69
, pp. 1237-1245
-
-
Momand, J.1
Zambetti, G.P.2
Olson, D.C.3
George, D.4
Levine, A.J.5
-
26
-
-
0026740449
-
Amplification of a gene encoding a p53-associated protein in human sarcomas
-
Oliner JD, Kinzler KW, Meltzer PS, George DL, Vogelstein B. Amplification of a gene encoding a p53-associated protein in human sarcomas. Nature 1992;358:80-3.
-
(1992)
Nature
, vol.358
, pp. 80-83
-
-
Oliner, J.D.1
Kinzler, K.W.2
Meltzer, P.S.3
George, D.L.4
Vogelstein, B.5
-
27
-
-
0027325132
-
Oncoprotein mdm2 conceals the activation domain of tumour suppressor p53
-
Oliner JD, Pietenpol JA, Thiagalingam S, Gyuris J, Kinzler KW, Vogelstein B. Oncoprotein mdm2 conceals the activation domain of tumour suppressor p53. Nature 1993;362:857-60.
-
(1993)
Nature
, vol.362
, pp. 857-860
-
-
Oliner, J.D.1
Pietenpol, J.A.2
Thiagalingam, S.3
Gyuris, J.4
Kinzler, K.W.5
Vogelstein, B.6
-
28
-
-
0027179604
-
Identification and characterisation of multiple mdm2 proteins and mdm2-p53 protein complexes
-
Olson DC, Marechal V, Momand J, Chen J, Romocki C, Levine AJ. Identification and characterisation of multiple mdm2 proteins and mdm2-p53 protein complexes. Oncogene 1993;8:2353-60.
-
(1993)
Oncogene
, vol.8
, pp. 2353-2360
-
-
Olson, D.C.1
Marechal, V.2
Momand, J.3
Chen, J.4
Romocki, C.5
Levine, A.J.6
-
29
-
-
0027291285
-
Upregulation of mdm2 expression in meth a tumor cells tolerating wild type p53
-
Otto A, Deppert W. Upregulation of mdm2 expression in meth a tumor cells tolerating wild type p53. Oncogene 1993;8:2591-603.
-
(1993)
Oncogene
, vol.8
, pp. 2591-2603
-
-
Otto, A.1
Deppert, W.2
-
30
-
-
0029992335
-
p53 and MDM2 immunostaining in pulmonary blastomas and bronchiogenic carcinomas
-
Pacinda SJ, Ledet SC, Gondo MM, et al. p53 and MDM2 immunostaining in pulmonary blastomas and bronchiogenic carcinomas. Hum Pathol 1996;27:542-6.
-
(1996)
Hum Pathol
, vol.27
, pp. 542-546
-
-
Pacinda, S.J.1
Ledet, S.C.2
Gondo, M.M.3
-
31
-
-
0007267495
-
Amplification and over-expression of the mdm2 gene in human soft tissue tumours
-
Patterson H, Bares D, Gill S, et al. Amplification and over-expression of the mdm2 gene in human soft tissue tumours. Sarcoma 1997;1:17-22.
-
(1997)
Sarcoma
, vol.1
, pp. 17-22
-
-
Patterson, H.1
Bares, D.2
Gill, S.3
-
32
-
-
0027964904
-
Immunochemical analysis of the interaction of p53 with MDM2: Fine mapping of the MDM2 binding site on p53 using synthetic peptides
-
Picksley SM, Vojtesk B, Sparks A, Lane DP. Immunochemical analysis of the interaction of p53 with MDM2: fine mapping of the MDM2 binding site on p53 using synthetic peptides. Oncogene 1994;9:2523-9.
-
(1994)
Oncogene
, vol.9
, pp. 2523-2529
-
-
Picksley, S.M.1
Vojtesk, B.2
Sparks, A.3
Lane, D.P.4
-
33
-
-
0031046598
-
Distinct mdm2/p53 expression patterns in liposarcoma subgroups: Implications for different pathogenic mechanisms
-
Pilotti S, Della Torre G, Lavarino C, et al. Distinct mdm2/p53 expression patterns in liposarcoma subgroups: implications for different pathogenic mechanisms. J Pathol 1997;181:14-24.
-
(1997)
J Pathol
, vol.181
, pp. 14-24
-
-
Pilotti, S.1
Della Torre, G.2
Lavarino, C.3
-
34
-
-
0001812125
-
Enhanced mdm2 oncoprotein expression in soft tissue sarcoma: Several possible mechanisms
-
Pollock RE, Lang A, El-Naggar AK, Radinsky R, Hung MC. Enhanced mdm2 oncoprotein expression in soft tissue sarcoma: several possible mechanisms. Sarcoma 1997;1:23-9.
-
(1997)
Sarcoma
, vol.1
, pp. 23-29
-
-
Pollock, R.E.1
Lang, A.2
El-Naggar, A.K.3
Radinsky, R.4
Hung, M.C.5
-
35
-
-
0030028076
-
MDM2 amplification, p53 mutation, and accumulation of the p53 gene product in malignant fibrous histiocytoma
-
Reid AH, Tsai MM, Venzon DJ, Wright CE, Lack EE, O'Leary TJ. MDM2 amplification, p53 mutation, and accumulation of the p53 gene product in malignant fibrous histiocytoma. Diagn Mol Pathol 1996;5:65-73.
-
(1996)
Diagn Mol Pathol
, vol.5
, pp. 65-73
-
-
Reid, A.H.1
Tsai, M.M.2
Venzon, D.J.3
Wright, C.E.4
Lack, E.E.5
O'Leary, T.J.6
-
36
-
-
0029824669
-
Alternatively spliced mdm2 transcripts with loss of p53 binding domain sequences: Transforming ability and frequent detection in human cancer
-
Sigalas I, Calvert AH, Anderson JJ, Neal DE, Lunec J. Alternatively spliced mdm2 transcripts with loss of p53 binding domain sequences: transforming ability and frequent detection in human cancer. Nature Med 1996;2:912-7.
-
(1996)
Nature Med
, vol.2
, pp. 912-917
-
-
Sigalas, I.1
Calvert, A.H.2
Anderson, J.J.3
Neal, D.E.4
Lunec, J.5
-
37
-
-
0028915250
-
Characterisation of epitopes on human p53 using phage-displayed peptide libraries: Insight into antibody-peptide interactions
-
Stephen CW, Helminen P, Lane DP. Characterisation of epitopes on human p53 using phage-displayed peptide libraries: insight into antibody-peptide interactions. J Mol Biol 1995;248:58-78.
-
(1995)
J Mol Biol
, vol.248
, pp. 58-78
-
-
Stephen, C.W.1
Helminen, P.2
Lane, D.P.3
-
38
-
-
0029810442
-
Prognosis is correlated with p53 mutation type for soft tissue sarcoma patients
-
Taubert H, Meye A, Würl P. Prognosis is correlated with p53 mutation type for soft tissue sarcoma patients. Cancer Res 1996; 56:4134-6.
-
(1996)
Cancer Res
, vol.56
, pp. 4134-4136
-
-
Taubert, H.1
Meye, A.2
Würl, P.3
-
39
-
-
0029145778
-
Molecular and immunohistochemical p53 status in liposarcoma and malignant fibrous histiocytoma
-
Taubert H, Würl P, Meye A, et al. Molecular and immunohistochemical p53 status in liposarcoma and malignant fibrous histiocytoma. Cancer 1995;76:1187-96.
-
(1995)
Cancer
, vol.76
, pp. 1187-1196
-
-
Taubert, H.1
Würl, P.2
Meye, A.3
-
40
-
-
0029952064
-
High levels of mdm2 are not correlated with the presence of wild-type p53 in human malignant mesothelioma cell lines
-
Ungar S, Van de Meeren A, Tammilehto L, Linnainmaa K, Mattson K, Gerwin BI. High levels of mdm2 are not correlated with the presence of wild-type p53 in human malignant mesothelioma cell lines. Br J Cancer 1996;74:1534-40.
-
(1996)
Br J Cancer
, vol.74
, pp. 1534-1540
-
-
Ungar, S.1
Van De Meeren, A.2
Tammilehto, L.3
Linnainmaa, K.4
Mattson, K.5
Gerwin, B.I.6
-
41
-
-
0008702656
-
Grading of soft tissue sarcomas: Experience of the EORTC soft tissue sarcoma group
-
Ryan JR, Baker LO, eds. Dordrecht, The Netherlands: Kluwer Academic
-
Van Unnik JAM, Coindre JM, Contesso G, et al. Grading of soft tissue sarcomas: experience of the EORTC soft tissue sarcoma group. In: Ryan JR, Baker LO, eds. Recent concepts in sarcoma treatment. Dordrecht, The Netherlands: Kluwer Academic, 1988: 7-13.
-
(1988)
Recent Concepts in Sarcoma Treatment
, pp. 7-13
-
-
Van Unnik, J.A.M.1
Coindre, J.M.2
Contesso, G.3
-
42
-
-
0030615220
-
p21WAF1/CIP1 and mdm2 expression in non-Hodgkin's lymphoma and their relationship to p53 status: A p53+, mdm2-, p21- Immunophenotype associated with missense p53 mutations
-
Villuendas R, Pezzella F, Gatter K, et al. p21WAF1/CIP1 and mdm2 expression in non-Hodgkin's lymphoma and their relationship to p53 status: a p53+, mdm2-, p21-immunophenotype associated with missense p53 mutations. J Pathol 1997;181:51-61.
-
(1997)
J Pathol
, vol.181
, pp. 51-61
-
-
Villuendas, R.1
Pezzella, F.2
Gatter, K.3
-
43
-
-
0027136159
-
Infrequency of mdm2 gene amplification in pediatric solid tumors and lack of association with p53 mutations in adult squamous cell carcinomas
-
Waber PG, Chen J, Nisen PD. Infrequency of mdm2 gene amplification in pediatric solid tumors and lack of association with p53 mutations in adult squamous cell carcinomas. Cancer Res 1993; 53:6028-30.
-
(1993)
Cancer Res
, vol.53
, pp. 6028-6030
-
-
Waber, P.G.1
Chen, J.2
Nisen, P.D.3
-
45
-
-
0345556004
-
Frequent occurrence of p53 mutations in rhabdomyosarcoma and leiomyosarcoma, but not in fibrosarcoma and malignant neural tumors
-
Würl P, Taubert H, Bache M, et al. Frequent occurrence of p53 mutations in rhabdomyosarcoma and leiomyosarcoma, but not in fibrosarcoma and malignant neural tumors. Int J Cancer 1996;69: 317-23.
-
(1996)
Int J Cancer
, vol.69
, pp. 317-323
-
-
Würl, P.1
Taubert, H.2
Bache, M.3
-
46
-
-
9844229070
-
Prognostic value of immunohistochemistry for p53 in primary soft tissue sarcomas: A multivariate analysis of five antibodies
-
Würl P, Taubert H, Meye A, et al. Prognostic value of immunohistochemistry for p53 in primary soft tissue sarcomas: a multivariate analysis of five antibodies. J Cancer Res Clin Oncol 1997; 123:502-8.
-
(1997)
J Cancer Res Clin Oncol
, vol.123
, pp. 502-508
-
-
Würl, P.1
Taubert, H.2
Meye, A.3
-
47
-
-
0029028354
-
Interaction between the retinoblastoma protein and the oncoprotein mdm2
-
Xiao ZX, Chen J, Levine AJ, et al. Interaction between the retinoblastoma protein and the oncoprotein mdm2. Nature 1995;375: 694-8.
-
(1995)
Nature
, vol.375
, pp. 694-698
-
-
Xiao, Z.X.1
Chen, J.2
Levine, A.J.3
|