Antifungal activity of fluconazole in combination with lovastatin and their effects on gene expression in the ergosterol and prenylation pathways in Candida albicans

Medical Mycology

Volumn 41, Issue 5, 2003, Pages 417-425

  Song, Jia L ^a,b   Lyons, Chris N ^a,b   Holleman, Scott ^a,b   Oliver, Brian G ^a,b   White, Theodore C ^a,b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b SEATTLE BIOMEDICAL RESEARCH INSTITUTE   (United States)

Author keywords

Candida albicans; Drugs; Ergosterol; Prenylation

Indexed keywords

ERGOSTEROL; FLUCONAZOLE; GERANYLGERANYL TRANSFERASE SUBUNIT; GERANYLTRANSFERASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LANOSTEROL 14ALPHA DEMETHYLASE INHIBITOR; MEVINOLIN; PROTEIN FARNESYLTRANSFERASE; PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT; SQUALENE SYNTHASE; STEROL; STEROL 14ALPHA DEMETHYLASE; UNCLASSIFIED DRUG; UNCLASSIFIED ENZYME;

ANTIFUNGAL ACTIVITY; ARTICLE; CANDIDA ALBICANS; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENTIATION; DRUG RESPONSE; DRUG SENSITIVITY; FUNGAL STRAIN; FUNGUS CULTURE; GENE EXPRESSION; IN VITRO STUDY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRENYLATION;

BASE SEQUENCE; CANDIDA ALBICANS; DNA PRIMERS; DRUG SYNERGISM; ERGOSTEROL; FLUCONAZOLE; GENE EXPRESSION REGULATION, FUNGAL; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; LOVASTATIN; MICROBIAL SENSITIVITY TESTS; PROTEIN ISOPRENYLATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

CANDIDA; CANDIDA ALBICANS; FUNGI;

EID: 0344876477     PISSN: 13693786     EISSN: None     Source Type: Journal    
DOI: 10.1080/1369378031000137233     Document Type: Article

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