Overexpression of Ogg1 in mammalian cells: Effects on induced and spontaneous oxidative DNA damage and mutagenesis

Carcinogenesis

Volumn 20, Issue 9, 1999, Pages 1863-1868

  Hollenbach, Stephan ^b   Dhénaut, Andreia ^a   Eckert, Inge ^b   Radicella, J Pablo ^a   Epe, Bernd ^b  

^a INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE   (France)

^b JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DNA GLYCOSYLTRANSFERASE; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; PHOTOSENSITIZING AGENT; POTASSIUM BROMATE;

ANIMAL CELL; ARTICLE; CHO CELL; CONTROLLED STUDY; DNA ADDUCT; DNA DAMAGE; DNA REPAIR; DNA TRANSFECTION; MUTAGENICITY; MUTATION RATE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SPONTANEOUS MUTATION;

ANIMALS; BROMATES; CELL LINE; CRICETINAE; CRICETULUS; DNA DAMAGE; DNA REPAIR; DNA-FORMAMIDOPYRIMIDINE GLYCOSYLASE; ENZYME INDUCTION; FEMALE; GENES, BACTERIAL; GENES, REPORTER; MUTAGENESIS; N-GLYCOSYL HYDROLASES; OVARY; OXIDANTS; OXIDATIVE STRESS; PHOTOCHEMISTRY; PHOTOSENSITIZING AGENTS; POLYMERASE CHAIN REACTION; PYRROLIDINES; QUINOLIZINES; TRANSFECTION;

EID: 0344855595     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/20.9.1863     Document Type: Article

References (38)

1. Wood, M.L., Dizdaroglu, M., Gajewski, E. and Essigmann, J.M. (1990) Mechanistic studies of ionizing radiation and oxidative mutagenesis: genetic effects of a single 8-hydroxyguanine (7-hydro-8-oxoguanine) residue inserted at a unique site in a viral genome. Biochemistry, 29, 7024-7032.
2. Cheng, K.C., Cahill, D.S., Kasai, H., Nishimura, S. and Loeb, L.A. (1992) 8-Hydroxyguanine, an abundant form of oxidative DNA damage, cause G→T and A→C substitutions. J. Biol. Chem., 267, 166-172.
3. Moriya, M. (1993) Single-stranded shuttle phagemid for mutagenesis studies in mammalian cells: 8-oxoguanine in DNA induces targeted GC→TA transversions in simian kidney cells. Proc. Natl Acad. Sci. USA, 90, 1122-1126.
4. Collins, A.R., Cadet, J., Epe, B. and Gedik, C. (1997) Problems in the measurement of 8-oxoguanine in human DNA. Report of a workshop, DNA oxidation, held in Aberdeen, UK, 19-21 January, 1997. Carcinogenesis, 18, 1833-1836.
5. Demple, B. and Harrison, L. (1994) Repair of oxidative damage to DNA: enzymology and biology. Anna. Rev. Biochem., 63, 915-948.
6. Wood, R.D. (1996) DNA repair in eukaryotes. Annu. Rev. Biochem., 65, 135-167.
7. Cunningham, R.P. (1997) DNA glycosylases. Mutat. Res., 383, 189-196.
8. Boiteux, S. and Radicella, J.P. (1998) Excision repair of 8-oxoguanine in eukaryotes: the OGG1 proteins. In Dizdaroglu, M. and Karakaya, A. (eds) Advances in DNA Damage and Repair. Plenum Press, New York, NY, pp. 35-45.
9. Arai, K., Morishita, K., Shinmura, K., Kohno, T., Kim, S.R., Nohmi, T., Taniwaki, M., Ohwada, S. and Yokota, J. (1997) Cloning of a human homolog of the yeast OGG1 gene that is involved in the repair of oxidative DNA damage. Oncogene, 14, 2857-2861.
10. Aburatani, H., Hippo, Y., Ishida, T., Takashima, R., Matsuba, C., Kodama, T., Takao, M., Yasui, A., Yamamoto, K., Asano, M., Fukasawa, K. et al. (1997) Cloning and characterization of mammalian 8-hydroxyguanine-specific DNA glycosylase/apurinic, apyrimidinic lyase, a functional mutM homologue. Cancer Res., 57, 2151-2156.
11. Bjoras, M., Luna, L., Johnsen, B., Hoff, E., Haug, T., Rognes, T. and Seeberg, E. (1997) Opposite base-dependent reactions of a human base excision repair enzyme on DNA containing 7,8-dihydro-8-oxoguanine and abasic sites. EMBO J., 16, 6314-6322.
12. Lu, R., Nash, H.M. and Verdine, G.L. (1997) A mammalian DNA repair enzyme that excises oxidatively damaged guanine maps to a locus frequently lost in lung cancer. Curr. Biol., 7, 397-407.
13. Radicella, J.P., Dherin, C., Desmaze, C., Fox, M.S. and Boiteux, S. (1997) Cloning and characterization of hOGG1, a human homolog of the OGG1 gene of Saccharomyces cerevisiae. Proc. Natl Acad. Sci. USA, 94, 8010-8015.
14. Roldan-Arjona, T., Wei, Y.F., Carter, K.C., Klungland, A., Anselmino, C., Wang, R.P., Augustus, M. and Lindahl, T. (1997) Molecular cloning and functional expression of a human cDNA encoding the antimutator enzyme 8-hydroxyguanine-DNA glycosylase. Proc. Natl Acad. Sci. USA, 94, 8016-8020.
15. Rosenquist, T.A., Zharkov, D.O. and Groilman, A.P. (1997) Cloning and characterization of a mammalian 8-oxoguanine DNA glycosylase. Proc. Natl Acad. Sci. USA, 94, 7429-7434.
16. Michaels, M.L., Cruz, C., Grollman, A.P. and Miller, J.H. (1992) Evidence that MutY and MutM combine to prevent mutations by an oxidative damaged form of guanine. Proc. Natl Acad. Sci. USA, 89, 7022-7025.
17. Thomas, D., Scot, A.D., Barbey, R., Padula, M. and Boiteux, S. (1997) Inactivation of OGG1 increases the incidence of G:C→T:A transversions in Saccharomyces cerevisiae: evidence for endogenous oxidative damage to DNA in eukaryotic cells. Mol. Gen. Genet., 254, 171-178.
18. Fishel, R., Lescoe, M.K., Rao, M.R.S., Copeland, N.G., Jenkins, N.A., Garber, J., Kane, M. and Kolodner, R. (1993) The human mutator homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Cell, 75, 1027-1038.
19. Modrich, P. (1994) Mismatch repair, genetic stability and cancer. Science, 266, 1959-1960.
20. Chevillard, S., Radicella, J.P., Levalois, C., Lebeau, J., Poupon, M.-F., Oudard, S., Dutrillaux, B. and Boiteux, S. (1998) Mutations in OGG1, a gene involved in the repair of oxidative DNA damage, are found in human lung and kidney tumours. Oncogene, 16, 3083-3086.
21. Tindall, K.R. and Stankowski, L.F.Jr (1989) Molecular analysis of spontaneous mutations at the gpt locus in Chinese hamster ovary (AS52) cells. Mutat. Res., 220, 241-253.
22. Boiteux, S., O'Connor, T.R., Lederer, F., Gouyette, A. and Laval, J. (1990) Homogeneous Escherichia coli Fpg protein. J. Biol. Chem., 265, 3916-3922.
23. Girard, P.M., D'Ham, C., Cadet, J. and Boiteux, S. (1998) Opposite base-dependent excision of 7,8-dihydro-8-oxoadenine by the Ogg1 protein of Saccharomyces cerevisiae. Carcinogenesis, 19, 1299-1305.
24. Kohn, K.W., Erickson, L.C., Ewig, R.A.G. and Friedman, C.A. (1976) Fractionation of DNA from mammalian cells by alkaline elution. Biochemistry, 15, 4629-4637.
25. Epe, B. and Hegler, J. (1994) Oxidative DNA damage: endonuclease fingerprinting. Methods Enzymol., 234, 122-131.
26. Pflaum, M., Will, O. and Epe, B. (1997) Determination of steady-state levels of oxidative DNA base modifications in mammalian cells by means of repair endonucleases. Carcinogenesis, 18, 2225-2231.
27. Tindall, K.R., Stankowski, L.F.Jr, Machanoff, R. and Hsie, A.W. (1986) Analysis of mutation in pSV2 gpt-transformed CHO cells. Mutat. Res., 160, 121-131.
28. Glaab, W.E. and Tindall, K.R. (1997) Mutation rate at the hprt locus in human cancer cell lines with specific mismatch repair-gene defects. Carcinogenesis, 18, 1-8.
29. Ballmaier, D. and Epe, B. (1995) Oxidative DNA damage induced by potassium bromate under cell-free conditions and in mammalian cells. Carcinogenesis, 16, 335-342.
30. Epe, B. (1995) DNA damage profiles induced by oxidizing agents. Rev. Physiol. Biochem. Pharmacol., 127, 223-249.
31. Pflaum, M., Will, O., Mahler, H.C. and Epe, B. (1998) DNA oxidation products determined with repair endonucleases in mammalian cells: types, basal levels and influence of cell proliferation. Free Rad. Res., 29, 585-594.
32. Will, O., Gocke, E., Eckert, I., Schulz, I., Pflaum, M., Mahler, H.C. and Epe, B. (1999) Oxidative DNA damage and mutations induced by a polar photosensitizer, Ro19-8022. Mutat. Res., in press.
33. Kasai, H., Crain, P.F., Kuchino, Y., Nishimura, S., Ootsuyama, A. and Tanooka, H. (1986) Formation of 8-hydroxyguanine moiety in cellular DNA by agents producing oxygen radicals and evidence for its repair. Carcinogenesis, 7, 1849-1851.
34. Jaruga, P. and Dizdaroglu, M. (1996) Repair of products of oxidative DNA damage in human cells. Nucleic Acids Res., 24, 1389-1394.
35. Dally, H. and Hartwig, A. (1997) Induction and repair of oxidative DNA damage by nickel(II) and cadmium(II) in mammalian cells. Carcinogenesis, 18, 1021-1026.
36. Will, O., Schindler, D., Boiteux, S. and Epe, B. (1998) Fanconi's anaemia cells have normal steady-state levels and repair of oxidative DNA base modifications sensitive to Fpg protein. Mutat. Res., 409, 65-72.
37. Klein, J.C., Bleeker, M.J., Saris, C.P., Roelen, H.C.P.F., Brugghe, H.F., van den Elst, H., van der Marel, G.A., van Boom, J.H., Westra, J.G., Kriek, E. and Bems, A.J.M. (1992) Repair and replication of plasmids with sitespecific 8-oxodG and 8-AAFdG residues in normal and repair-deficient human cells. Nucleic Acids Res., 20, 4437-4443.
38. Le Page, F., Guy, A., Cadet, J., Sarasin, A. and Gentil, A. (1998) Repair and mutagenic potency of 8-oxoG:A and 8-oxoG:C base pairs in mammalian cells. Nucleic Acids Res., 26, 1276-1281.