DNA oxidation products determined with repair endonucleases in mammalian cells: Types, basal levels and influence of cell proliferation

Free Radical Research

Volumn 29, Issue 6, 1998, Pages 585-594

  Pflaum, Michael ^a   Will, Olaf ^a   Mahler, Hanns Christian ^a   Epe, Bernd ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

8 hydroxyguanine; Alkaline elution; Fpg protein; Oxidative DNA damage; Steady state level

Indexed keywords

ACRIDINE ORANGE; DNA BASE; ENDONUCLEASE; GUANINE DERIVATIVE; HYDROXYL RADICAL; MITOCHONDRIAL DNA; PEROXYNITRITE; PHOTOSENSITIZING AGENT; PROTEIN; PYRIMIDINE DERIVATIVE; RIBOFLAVIN;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; DNA DAMAGE; DNA MODIFICATION; DNA REPAIR; HUMAN; HUMAN CELL; LYMPHOCYTE; MAMMAL CELL; NONHUMAN; OXIDATION; RAT; SWINE;

ANIMALIA; MAMMALIA; SUIDAE; SUS SCROFA;

EID: 0032468725     PISSN: 10715762     EISSN: None     Source Type: Journal    
DOI: 10.1080/10715769800300631     Document Type: Article

References (48)

1. L.H. Breimer (1990) Molecular mechanisms of oxygen radical carcinogenesis and mutagenesis: the role of base damage. Molecular Carcinogenesis, 3, 188-197.
2. D.I. Feig, L.C. Sowers and L.A. Loeb (1994) Reverse chemical mutagenesis: Identification of the mutagenic lesions resulting from reactive oxygen species-mediated damage to DNA. Proceedings of the National Academy of Sciences USA, 91, 6609-6613.
3. M.L. Wood, M. Dizdaroglu, F. Gajewski and J.M. Essigmann (1990) Mechanistic studies of ionizing radiation and oxidative mutagenesis: genetic effects of a single 8-hydroxyguanine (7-hydro-8-oxoguanine) residue inserted at a unique site in a viral genome. Biochemistry, 29, 7024-7032.
4. K.C. Cheng, D.S. Cahill, H. Kasai, S. Nishimura and L.A. Loeb (1992) 8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G → T and A → C substitutions. The Journal of Biological Chemistry, 267, 166-172.
5. M. Moriya (1993) Single-stranded shuttle phagemid for mutagenesis studies in mammalian cells: 8-oxoguanine in DNA induces targeted GC → TA transversions in simian kidney cells. Proceedings of the National Academy of Sciences USA, 90, 1122-1126.
6. D.G. Wallace (1992) Mitochondrial genetics: a paradigm for aging and degenerative diseases? Science, 256, 628-632.
7. J.M.C. Gutteridge (1993) Free radicals in disease processes: a compilation of cause and consequences. Free Radical Research Communications, 19, 141-158.
8. K.B. Beckman and B.N. Ames (1998) The free radical theory of aging matures. Physiological Reviews, 78, 547-581.
9. H. Kasai, F.F. Crain, Y. Kuchino, S. Nishimura, A. Ootsuyama and H. Tanooka (1986) Formation of 8-hydroxyguanine moiety in cellular DNA by agents producing oxygen radicals and evidence for its repair. Carcinogenesis, 7, 1849-1851.
10. Z. Nackerdien, R. Olinski and M. Dizdaroglu (1992) DNA base damage in chromatin of 7-irradiated cultured human cells. Free Radical Research Communications, 16, 259-273.
11. 32P-postlabeling assay and the basal levels in rat tissues. Carcinogenesis, 17, 917-924.
12. B. Halliwell and M. Dizdaroglu (1992) The measurement of oxidative damage to DNA by HPLC and GC/MS techniques. Free Radical Research Communications, 16, 75-67.
13. A.R. Collins, J. Cadet, B. Epe and C. Gedik (1997) Problems in the measurement of 8-oxoguanine in human DNA. Report of a workshop, DNA oxidation, held in Aberdeen, UK, 19-21 January, 1997. Carcinogenesis, 18, 1833-1836.
14. J.L. Ravanat, R.J. Turesky, F. Gremaud, L.J. Trudel and R. Stadler (1995) Determination of 8-oxoguanine in DNA by gas chromatography - mass spectrometry and HPLC - electrochemical detection: overestimation of the background level of the oxidized base by the gas chromatography - mass spectrometry assay. Chemical Research in Toxicology, 8, 1039-1045.
15. M. Hamberg and L.-Y. Zhang (1995) Quantitative determination of 8-hydroxyguanine by isotope dilution mass spectrometry. Analytical Biochemistry, 229, 336-344.
16. T. Douki, T. Delatour, F. Bianchini and J. Cadet (1996) Observation and prevention of an artifactual formation of oxidised DNA bases and nucleosides in the GC-EIMS method. Carcinogenesis, 17, 347-353.
17. M. Nakajima, T. Takeuchi and K. Morimoto (1996) Determination of 8-hydroxydeoxyguanosine in human cells under oxygen-free conditions. Carcinogenesis, 17, 787-791.
18. M.T.V. Finnegan, K.F. Herbert, M.D. Evans, H.R. Griffiths and J. Lunec (1996) Evidence for sensitization of DNA to oxidative damage during isolation. Free Radicals in Biology and Medicine, 20, 93-98.
19. F. Kvam and R.M. Tyrrell (1997) Induction of oxidative DNA base damage in human skin cells by UV and near visible radiation. Carcinogenesis, 18, 2379-2384.
20. 33P-postlabeling and electrochemical detection. Carcinogenesis, 18, 2367-2371.
21. H.J. Helbock, K.B. Beckman, M.K. Shigenaga, P.B. Walter, A.A. Woodall, H.C. Yeo and B. Ames (1998) DNA oxidation matters: The HPLC electrochemical detection assay of 8-oxo-deoxyguanosine and 8-oxo-guanine. Proceedings of the National Academy of Sciences USA, 95, 288-293.
22. M. Pflaum, O. Will and B. Epe (1997) Determination of steady-state levels of oxidative DNA base modifications in mammalian cells by means of repair endonucleases. Carcinogenesis, 18, 2225-2231.
23. A.R. Collins, S.J. Duthie, L. Fillion, C.M. Gedik, N. Vaughan and S.G. Wood (1997) Oxidative DNA damage in human cells: the influence of antioxidants and DNA repair. Biochemical Society Transactions, 25, 326-331.
24. A. Hartwig and R. Schlepegrell (1995) Induction of oxidative DNA damage by ferric iron in mammalian cells. Carcinogenesis, 16, 3009-3013.
25. S. Czene and M. Harms-Ringdahl (1995) Detection of single-strand breaks and formamidopyrimidine-DNA glycosylase-sensitive sites in DNA of cultured human fibroblasts. Mutation Research, 336, 235-242.
26. B. Epe and J. Hegler (1994) Oxidative DNA damage: endonuclease fingerprinting. Methods in Enzymology, 234, 122-131.
27. J. Hegler, D. Bittner, S. Boiteux and B. Epe (1993) Quantification of oxidative DNA modifications in mitochondria. Carcinogenesis, 14, 2309-2312.
28. K.R. Tindall and L.F. Stankowski Jr. (1989) Molecular analysis of spontanous mutations at the gpt locus in Chinese hamster ovary (AS52) cells. Mutation Research, 220, 241-235.
29. P. Boukamp, R.T. Petrussevska, D. Breitkreutz, J. Hornung, A. Markham and N.E. Fusenig (1988) Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line. The Journal of Cell Biology, 106, 761-771.
30. M. Salditt, S.N. Braunstein, R.D. Camerini-Otero and R.M. Franklin (1972) Structure and synthesis of a lipid-containing bacteriophage. Virology, 48, 259-262.
31. S. Boiteux, T.R. O'Connor, F. Lederer, A. Gouyette and J. Laval (1990) Homogeneous Escherichia coli Fpg protein. The Journal of Biological Chemistry, 265, 3916-3922.
32. Y. Nakabeppu, K. Yamashita and M. Sekiguchi (1982) Purification and characterization of normal and mutant forms of T4 endonuclease V. Proceedings of the National Academy of Sciences USA, 257, 2556-2562.
33. C. Richter, J. Park and B. Ames (1988) Normal oxidative damage to mitochondrial and nuclear-DNA is extensive. Proceedings of the National Academy of Sciences USA, 85, 6465-6467.
34. K.W. Kohn, L.C. Erickson, R.A.G. Ewig and C.A. Friedman (1976) Fractionation of DNA from mammalian cells by alkaline elution. Biochemistry, 15, 4629-4637.
35. B. Epe, M. Pflaum and S. Boiteux (1993) DNA damage induced by photo-sensitizers in cellular and cell-free systems. Mutation Research, 299, 135-145.
36. D. Ballmaier and B. Epe (1995) Oxidative DNA damage induced by potassium bromate under cell-free conditions and in mammalian cells. Carcinogenesis, 16, 335-342.
37. B. Epe, M. Häring, D. Ramaiah, H. Stopper, M.M. Abou-Elzahab, W. Adam and C.R. Saha-Möller (1993) DNA damage induced by furocoumarin hydroperoxides plus UV (360 nm). Carcinogenesis, 14, 2271-2276.
38. B. Epe, D. Ballmaier, W. Adam, G.N. Grimm and C.R. Saha-Möller (1996) Photolysis of-N-hydroxypyridinethiones: a new source of hydroxyl radicals for the direct damage of cell-free and cellular DNA. Nucleic Acids Research, 24, 1625-1631.
39. B. Epe, D. Ballmaier, I. Roussyn, K. Briviba and H. Sies (1996) DNA damage by peroxynitrite characterized with DNA repair enzymes. Nucleic Acids Research, 24, 4105-4110.
40. T. Lindahl (1990) Repair of intrinsic DNA lesions. Mutation Research, 238, 305-311.
41. S. Boiteux (1993) Properties and biological functions of the NTH and FPG proteins of Escherichia coli: two DNA glycosylases that repair oxidative damage in DNA. Photochemistry and Photobiology B: Biology, 19, 87-96.
42. B. Demple and L. Harrison (1994) Repair of oxidative damage to DNA: enzymology and biology. Annual Review of Biochemistry, 63, 915-948.
43. A. Karakaya, P. Jaruga, V.A. Bohr, A.P. Grollman and M. Dizdaroglu (1997) Kinetics of excision of purine lesions from DNA by Escherichia coli Fpg protein. Nucleic Acids Research, 25, 474-479.
44. M. Häring, H. Rüdiger, B. Demple, S. Boiteux and B. Epe (1994) Recognition of oxidized abasic sites by repair endonucleases. Nucleic Acids Research, 22, 2010-2015.
45. C. Kielbassa, L. Roza and B. Epe (1997) Wavelength dependence of oxidative DNA damage induced by UV and visible light. Carcinogenesis, 18, 811-816.
46. M. Pflaum, S. Boiteux and B. Epe (1994) Visible light generates oxidative DNA base modifications in high excess of strand breaks in mammalian cells. Carcinogenesis, 15, 297-300.
47. X.C. Le, J.Z. Xing, J. Lee, S.A. Leadon and M. Weinfeld (1998) Inducible repair of thymine glycol detected by an ultrasensitive assay for DNA damage. Science, 280, 1066-1069.
48. G.W. Buchko, J. Cadet, B. Morin and M. Weinfeld (1995) Photooxidation of d(TpG) by riboflavin and methylene blue. Isolation and characterization of thymidylyl-(3′,5′)-2-amino-5-[2′-deoxy-β-D-erythro- pentafuranosyl)amino]-4H-imidazol-4-one and its primary decomposition product thymidylyl-(3′,5′)-2-amino-5-[2′-deoxy-β-D-erythro- pentafuranosyl)amino]-5(2H)-oxazolone. Nucleic Acids Research, 23, 3954-3961.