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Volumn 19, Issue 1, 2003, Pages 6-11

Biological evaluation of an antibiotic DC-81 - Indole conjugate agent in human melanoma cell lines

Author keywords

DC 81; Indole carboxylate moiety; Melanoma; PBDs; Pyrrolo 2,1 c 1,4 benzodiazepines; XTT assay

Indexed keywords

1,2,3,11A TETRAHYDRO 8 HYDROXY 7 METHOXY 5H PYRROLO[2,1 C][1,4]BENZODIAZEPIN 5 ONE; ANTINEOPLASTIC ANTIBIOTIC; CARBOXYLIC ACID DERIVATIVE; INDOLE DERIVATIVE; NUCLEIC ACID SYNTHESIS INHIBITOR; PYRROLO[2,1 C][1,4]BENZODIAZEPINE DERIVATIVE;

EID: 0344838629     PISSN: 02575655     EISSN: None     Source Type: Journal    
DOI: 10.1016/s1607-551x(09)70441-3     Document Type: Article
Times cited : (3)

References (21)
  • 1
    • 0017642450 scopus 로고
    • Pyrrolo(1,4)benzodiazepine antitumor antibiotics. Comparative aspects of anthramycin, tomaymycin and sibiromycin
    • Hurley LH. Pyrrolo(1,4)benzodiazepine antitumor antibiotics. Comparative aspects of anthramycin, tomaymycin and sibiromycin. J Antibiot 1977;30:349-70.
    • (1977) J Antibiot , vol.30 , pp. 349-370
    • Hurley, L.H.1
  • 4
    • 0018568879 scopus 로고
    • Proposed structure of the anthramycin-DNA adduct
    • Hurley LH, Petrusek RL. Proposed structure of the anthramycin-DNA adduct. Nature 1979;282:529-31.
    • (1979) Nature , vol.282 , pp. 529-531
    • Hurley, L.H.1    Petrusek, R.L.2
  • 5
    • 0023819065 scopus 로고
    • 2 adduct. Evidence for two covalent adducts with opposite orientations and stereochemistries at the covalent linkage site
    • 2 adduct. Evidence for two covalent adducts with opposite orientations and stereochemistries at the covalent linkage site. J Med Chem 1988;31: 583-90.
    • (1988) J Med Chem , vol.31 , pp. 583-590
    • Cheatham, S.1    Kook, A.2    Hurley, L.H.3
  • 6
    • 0026746329 scopus 로고
    • Template-directed design of a DNA-DNA cross-linker based upon a bis-tomaymycin-duplex adduct
    • Wang JJ, Hill GC, Hurley LH. Template-directed design of a DNA-DNA cross-linker based upon a bis-tomaymycin-duplex adduct. J Med Chem 1992;35:2995-3002.
    • (1992) J Med Chem , vol.35 , pp. 2995-3002
    • Wang, J.J.1    Hill, G.C.2    Hurley, L.H.3
  • 7
    • 0028063086 scopus 로고
    • Comparison of a DSB-120 DNA interstrand cross-linked adduct with the corresponding bis-tomaymycin adduct: An example of a successful template-directed approach to drug design based upon the monoalkylating compound tomaymycin
    • Mountzouris JA, Wang JJ, Thurston DE, Hurley LH. Comparison of a DSB-120 DNA interstrand cross-linked adduct with the corresponding bis-tomaymycin adduct: an example of a successful template-directed approach to drug design based upon the monoalkylating compound tomaymycin. J Med Chem 1994;37:3132-40.
    • (1994) J Med Chem , vol.37 , pp. 3132-3140
    • Mountzouris, J.A.1    Wang, J.J.2    Thurston, D.E.3    Hurley, L.H.4
  • 8
    • 0013852032 scopus 로고
    • Isolation and characterization of anthramycin, a new antitumor antibiotic
    • Leimgruber W, Stefanovic V, Schenker F, et al. Isolation and characterization of anthramycin, a new antitumor antibiotic. J Am Chem Soc 1965;87:5791-3.
    • (1965) J Am Chem Soc , vol.87 , pp. 5791-5793
    • Leimgruber, W.1    Stefanovic, V.2    Schenker, F.3
  • 10
    • 0015377787 scopus 로고
    • Studies on tomaymycin, a new antibiotic. Isolation and properties of tomaymycin
    • Arima K, Kohsaka M, Tamura G, et al. Studies on tomaymycin, a new antibiotic. Isolation and properties of tomaymycin. J Antibiot 1972;25:437-44.
    • (1972) J Antibiot , vol.25 , pp. 437-444
    • Arima, K.1    Kohsaka, M.2    Tamura, G.3
  • 12
    • 0344060925 scopus 로고    scopus 로고
    • Japanese Patent JP 58, 180, 487 [83, 180, 487] (CI. CO7D487/ 04) Kyowa Hakko Kogyo Co. Ltd., Jpn Kokai Tokkyo Kono, 21 Oct 1983, Appl. 82/63, 630, 16 Apr 1982. Chem Abstr 1984; 100:173150k
    • Japanese Patent JP 58, 180, 487 [83, 180, 487] (CI. CO7D487/ 04) Kyowa Hakko Kogyo Co. Ltd., Jpn Kokai Tokkyo Kono, 21 Oct 1983, Appl. 82/63, 630, 16 Apr 1982. Chem Abstr 1984; 100:173150k.
  • 13
    • 0035917337 scopus 로고    scopus 로고
    • An efficient synthesis of pyrrolo [2,1-c][1,4]benzodiazepine. Synthesis of the antibiotic DC-81
    • Hu WP, Wang JJ, Lin FL, et al. An efficient synthesis of pyrrolo [2,1-c][1,4]benzodiazepine. Synthesis of the antibiotic DC-81. J Org Chem 2001;66:2881-3.
    • (2001) J Org Chem , vol.66 , pp. 2881-2883
    • Hu, W.P.1    Wang, J.J.2    Lin, F.L.3
  • 14
    • 0035282633 scopus 로고    scopus 로고
    • Design, synthesis, and evaluation of a novel pyrrolobenzodiazepine DNA-interactive agent with highly efficient cross-linking ability and potent cytotoxicity
    • Gregson SJ, Howard PW, Hartley JA, et al. Design, synthesis, and evaluation of a novel pyrrolobenzodiazepine DNA-interactive agent with highly efficient cross-linking ability and potent cytotoxicity. J Med Chem 2001;44:737-48.
    • (2001) J Med Chem , vol.44 , pp. 737-748
    • Gregson, S.J.1    Howard, P.W.2    Hartley, J.A.3
  • 15
    • 0000143411 scopus 로고
    • Synthesis of DNA-interactive pyrrolo [2,1-c][1,4]benzodiazepines
    • Thurston DE, Bose DS. Synthesis of DNA-interactive pyrrolo [2,1-c][1,4]benzodiazepines. Chem Rev 1994;94:433-65.
    • (1994) Chem Rev , vol.94 , pp. 433-465
    • Thurston, D.E.1    Bose, D.S.2
  • 16
    • 0029912567 scopus 로고    scopus 로고
    • Synthesis of a novel GC-specific covalent-binding DNA affinity-cleavage agent based on pyrrolobenzodiazepines (PBDs)
    • Thurston DE, Morris SJ, Hartley JA. Synthesis of a novel GC-specific covalent-binding DNA affinity-cleavage agent based on pyrrolobenzodiazepines (PBDs). Chem Comm 1996:563-5.
    • (1996) Chem Comm , pp. 563-565
    • Thurston, D.E.1    Morris, S.J.2    Hartley, J.A.3
  • 17
    • 0035924236 scopus 로고    scopus 로고
    • Synthetic 2-aroylindole derivatives as a new class of potent tubulin-inhibitory, antimitotic agents
    • Mahboobi S, Pongratz H, Hufsky H, et al. Synthetic 2-aroylindole derivatives as a new class of potent tubulin-inhibitory, antimitotic agents. J Med Chem 2001;44:4535-53.
    • (2001) J Med Chem , vol.44 , pp. 4535-4553
    • Mahboobi, S.1    Pongratz, H.2    Hufsky, H.3
  • 18
    • 0025027922 scopus 로고
    • 3-(2-Carboxyindol-3-yl)propionic acid derivatives: Antagonists of the strychnine-insensitive glycine receptor associated with the N-methyl-D-aspartate receptor complex
    • Salituro FG, Harrison BL, Baron BM, et al. 3-(2-Carboxyindol-3-yl)propionic acid derivatives: antagonists of the strychnine-insensitive glycine receptor associated with the N-methyl-D-aspartate receptor complex. J Med Chem 1990;33:2944-6.
    • (1990) J Med Chem , vol.33 , pp. 2944-2946
    • Salituro, F.G.1    Harrison, B.L.2    Baron, B.M.3
  • 19
    • 0022549558 scopus 로고
    • Selective thromboxane synthetase inhibitors. 3. 1H-imidazol-1-yl-substituted benzo[b]furan-, benzo[b]thiophene-, and indole-2-and -3-carboxylic acids
    • Cross PE, Dickinson RP, Parry MJ, Randall MJ. Selective thromboxane synthetase inhibitors. 3. 1H-imidazol-1-yl-substituted benzo[b]furan-, benzo[b]thiophene-, and indole-2-and -3-carboxylic acids. J Med Chem 1986;29:1637-43.
    • (1986) J Med Chem , vol.29 , pp. 1637-1643
    • Cross, P.E.1    Dickinson, R.P.2    Parry, M.J.3    Randall, M.J.4
  • 20
    • 0023339383 scopus 로고
    • Biology of tumor progression in human melanocytes
    • Herlyn M, Clark WH, Rodeck U, et al. Biology of tumor progression in human melanocytes. Lab Invest 1987;56:461-74.
    • (1987) Lab Invest , vol.56 , pp. 461-474
    • Herlyn, M.1    Clark, W.H.2    Rodeck, U.3
  • 21
    • 84986452945 scopus 로고
    • The synthesis of XTT: A new tetrazolium reagent bioreducible to a water-soluble formazan
    • Paull KD, Shoemaker RH, Boyd MR, et al. The synthesis of XTT: a new tetrazolium reagent bioreducible to a water-soluble formazan. J Heterocyclic Chem 1988;25:911-4.
    • (1988) J Heterocyclic Chem , vol.25 , pp. 911-914
    • Paull, K.D.1    Shoemaker, R.H.2    Boyd, M.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.