메뉴 건너뛰기




Volumn 14, Issue 2, 1999, Pages 92-97

Characterization of a Porphyromonas gingivalis gene prtK that encodes a lysine-specific cysteine proteinase and three sequence-related adhesins

Author keywords

Adhesins; Lysine specific cysteine proteinase; Porphyromonas gingivalis

Indexed keywords

ADHESIN; BACTERIAL GENE; BACTERIAL INFECTION; CYSTEINE PROTEINASE; MOLECULAR CLONING; PROTEIN SYNTHESIS; VIRULENCE;

EID: 0033121176     PISSN: 09020055     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-302X.1999.140203.x     Document Type: Article
Times cited : (40)

References (29)
  • 1
    • 0030792046 scopus 로고    scopus 로고
    • The Tla protein of Porphyromonas gingivalis W50: A homolog of the RI protease precursor (PrpRI) is an outer membrane receptor required for growth on low levels of hemin
    • Aduse-Opoku J, Slaney JM, Rangarajan M, Muir J, Young KA, Curtis MA. The Tla protein of Porphyromonas gingivalis W50: a homolog of the RI protease precursor (PrpRI) is an outer membrane receptor required for growth on low levels of hemin. J Bacteriol 1997: 179: 4778-4788.
    • (1997) J Bacteriol , vol.179 , pp. 4778-4788
    • Aduse-Opoku, J.1    Slaney, J.M.2    Rangarajan, M.3    Muir, J.4    Young, K.A.5    Curtis, M.A.6
  • 3
    • 0030737648 scopus 로고    scopus 로고
    • Characterization of a cell-associated, protein complex of Porphyromonas gingivalis W50 containing Arg- and Lys-specific cysteine proteinases and adhesins
    • Bhogal PS, Slakeski N, Reynolds EC. Characterization of a cell-associated, protein complex of Porphyromonas gingivalis W50 containing Arg- and Lys-specific cysteine proteinases and adhesins. Microbiology 1997: 143: 2485-2495.
    • (1997) Microbiology , vol.143 , pp. 2485-2495
    • Bhogal, P.S.1    Slakeski, N.2    Reynolds, E.C.3
  • 5
    • 0029933060 scopus 로고    scopus 로고
    • Characterization of an adherence and antigenic determinant of the ArgI protease of Porphyromonas gingivalis which is present on multiple gene products
    • Curtis MA, Aduse-Opoku J, Slaney JM, Rangarajan M, Booth V, Cridland J, Shepherd P. Characterization of an adherence and antigenic determinant of the ArgI protease of Porphyromonas gingivalis which is present on multiple gene products. Infect Immun 1996: 64: 2532-2539.
    • (1996) Infect Immun , vol.64 , pp. 2532-2539
    • Curtis, M.A.1    Aduse-Opoku, J.2    Slaney, J.M.3    Rangarajan, M.4    Booth, V.5    Cridland, J.6    Shepherd, P.7
  • 6
    • 0027428951 scopus 로고
    • Purification and partial characterization of a lysine-specific protease of Porphyromonas gingivalis
    • Fujimura S, Shibata Y, Nakamura T. Purification and partial characterization of a lysine-specific protease of Porphyromonas gingivalis. FEMS Microbiol Lett 1993: 113: 133-137.
    • (1993) FEMS Microbiol Lett , vol.113 , pp. 133-137
    • Fujimura, S.1    Shibata, Y.2    Nakamura, T.3
  • 7
    • 0029819454 scopus 로고    scopus 로고
    • The hemagglutinin gene A (hagA) of Porphyromonas gingivalis 381 contains four large, contiguous, direct repeats
    • Han N, Whitlock J, Progulske-Fox A. The hemagglutinin gene A (hagA) of Porphyromonas gingivalis 381 contains four large, contiguous, direct repeats. Infect Immun 1996: 64: 4000-4007.
    • (1996) Infect Immun , vol.64 , pp. 4000-4007
    • Han, N.1    Whitlock, J.2    Progulske-Fox, A.3
  • 8
    • 0028909491 scopus 로고
    • Dependence of vascular permeability enhancement on cysteine proteinases in vesicles of Porphyromonas gingivalis
    • Imamura T, Potempa J, Pike RN, Travis J. Dependence of vascular permeability enhancement on cysteine proteinases in vesicles of Porphyromonas gingivalis. Infect Immun 1995: 63: 1999-2003.
    • (1995) Infect Immun , vol.63 , pp. 1999-2003
    • Imamura, T.1    Potempa, J.2    Pike, R.N.3    Travis, J.4
  • 9
    • 0028818827 scopus 로고
    • Effect of free and vesicle-bound cysteine proteinases of Porphyromonas gingivalis on plasma clot formation: Implications for bleeding tendency at periodontitis sites
    • Imamura T, Polempa J, Pike RN, Moore JN, Barton MH, Travis J. Effect of free and vesicle-bound cysteine proteinases of Porphyromonas gingivalis on plasma clot formation: implications for bleeding tendency at periodontitis sites. Infect Immun 1995: 63: 4877-4882.
    • (1995) Infect Immun , vol.63 , pp. 4877-4882
    • Imamura, T.1    Polempa, J.2    Pike, R.N.3    Moore, J.N.4    Barton, M.H.5    Travis, J.6
  • 10
    • 0030004180 scopus 로고    scopus 로고
    • Proteolytic inactivation of the leukocyte C5a receptor by proteinases derived from Porphyromonas gingivalis
    • Jagels MA, Travis J, Potempa J, Pike R, Hugli TE. Proteolytic inactivation of the leukocyte C5a receptor by proteinases derived from Porphyromonas gingivalis. Infect Immun 1996: 64: 1984-1991.
    • (1996) Infect Immun , vol.64 , pp. 1984-1991
    • Jagels, M.A.1    Travis, J.2    Potempa, J.3    Pike, R.4    Hugli, T.E.5
  • 11
    • 0027965730 scopus 로고
    • Purification and characterization of a novel arginine-specific cysteine proteinase (argingipain) involved in the pathogenesis of periodontal disease from the culture supernatant of Porphyromonas gingivalis
    • Kadowaki T, Yoneda M, Okamoto K, Maeda K, Yamamoto K. Purification and characterization of a novel arginine-specific cysteine proteinase (argingipain) involved in the pathogenesis of periodontal disease from the culture supernatant of Porphyromonas gingivalis. J Biol Chem 1994: 269: 21371-21378.
    • (1994) J Biol Chem , vol.269 , pp. 21371-21378
    • Kadowaki, T.1    Yoneda, M.2    Okamoto, K.3    Maeda, K.4    Yamamoto, K.5
  • 12
    • 0029936655 scopus 로고    scopus 로고
    • Trypsin-like protease activity of Porphyromonas gingivalis as a potential virulence factor in a murine lesion model
    • Kesavalu L, Holt SC, Ebersole JL. Trypsin-like protease activity of Porphyromonas gingivalis as a potential virulence factor in a murine lesion model. Microb Pathog 1996: 20: 1-10.
    • (1996) Microb Pathog , vol.20 , pp. 1-10
    • Kesavalu, L.1    Holt, S.C.2    Ebersole, J.L.3
  • 13
    • 0028931780 scopus 로고
    • Complete nucleotide sequence of a gene prtR of Porphyromonas gingivalis W50 encoding a 132 kDa protein that contains an arginine-specific, thiol endopeptidase domain and a haemagglutinin domain
    • Kirszbaum L, Sotiropoulos C, Jackson C, Cleal S, Slakeski N, Reynolds EC. Complete nucleotide sequence of a gene prtR of Porphyromonas gingivalis W50 encoding a 132 kDa protein that contains an arginine-specific, thiol endopeptidase domain and a haemagglutinin domain. Biochem Biophys Res Commun 1995: 207: 424-431.
    • (1995) Biochem Biophys Res Commun , vol.207 , pp. 424-431
    • Kirszbaum, L.1    Sotiropoulos, C.2    Jackson, C.3    Cleal, S.4    Slakeski, N.5    Reynolds, E.C.6
  • 14
    • 0028839251 scopus 로고
    • Construction and characterization of arginine-specific cysteine proteinase (Arg-gingipain)-deficient mutants of Porphyromonas gingivalis. Evidence for significant contribution of Arg-gingipain to virulence
    • Nakayama K, Kadowaki T, Okamoto K, Yamamoto K. Construction and characterization of arginine-specific cysteine proteinase (Arg-gingipain)-deficient mutants of Porphyromonas gingivalis. Evidence for significant contribution of Arg-gingipain to virulence. J Biol Chem 1995: 270: 23619-23626.
    • (1995) J Biol Chem , vol.270 , pp. 23619-23626
    • Nakayama, K.1    Kadowaki, T.2    Okamoto, K.3    Yamamoto, K.4
  • 15
    • 0031962568 scopus 로고    scopus 로고
    • Haemoglobin receptor protein is intragenically encoded by the cysteine proteinase-encoding genes and the haemagglutinin-encoding gene of Porphyromonas gingivalis
    • Nakayama K, Ratnayake DB, Tsukuba T, Kadowaki T, Yamamoto K, Fujimura S. Haemoglobin receptor protein is intragenically encoded by the cysteine proteinase-encoding genes and the haemagglutinin-encoding gene of Porphyromonas gingivalis. Mol Microbiol 1998: 27: 51-61.
    • (1998) Mol Microbiol , vol.27 , pp. 51-61
    • Nakayama, K.1    Ratnayake, D.B.2    Tsukuba, T.3    Kadowaki, T.4    Yamamoto, K.5    Fujimura, S.6
  • 17
    • 0026168310 scopus 로고
    • Pro-peptide as an intramolecular chaperone: Renaturation of denatured subtilisin E with a synthetic pro-peptide
    • Ohta Y, Hojo H, Aimoto S, Kobayashi T, Zhu X, Jordan F, Inouye M. Pro-peptide as an intramolecular chaperone: renaturation of denatured subtilisin E with a synthetic pro-peptide. Mol Microbiol 1991: 5: 1507-1510.
    • (1991) Mol Microbiol , vol.5 , pp. 1507-1510
    • Ohta, Y.1    Hojo, H.2    Aimoto, S.3    Kobayashi, T.4    Zhu, X.5    Jordan, F.6    Inouye, M.7
  • 18
    • 0029684438 scopus 로고    scopus 로고
    • Cloning and sequencing of the gene encoding a novel lysine-specific cysteine protease (lys-gingipain) in Porphyromonas gingivalis: Structural relationship with arginine-specific cysteine protease (arg-gingipain)
    • Okamoto K, Kadowaki T, Nakayama K, Yamamoto K. Cloning and sequencing of the gene encoding a novel lysine-specific cysteine protease (lys-gingipain) in Porphyromonas gingivalis: structural relationship with arginine-specific cysteine protease (arg-gingipain). J Biochem 1996: 120: 398-406.
    • (1996) J Biochem , vol.120 , pp. 398-406
    • Okamoto, K.1    Kadowaki, T.2    Nakayama, K.3    Yamamoto, K.4
  • 19
    • 0031018358 scopus 로고    scopus 로고
    • Molecular cloning and characterization of Porphyromonas gingivalis lysine-specific gingipain. A new member of an emerging family of pathogenic bacterial cysteine proteinases
    • Pavloff N, Pemberton PA, Potempa J, Chen W-C, Pike RN, Prochazka V, Kiefer MC, Travis J, Barr PJ. Molecular cloning and characterization of Porphyromonas gingivalis lysine-specific gingipain. A new member of an emerging family of pathogenic bacterial cysteine proteinases. J Biol Chem 1997: 272: 1595-600.
    • (1997) J Biol Chem , vol.272 , pp. 1595-1600
    • Pavloff, N.1    Pemberton, P.A.2    Potempa, J.3    Chen, W.-C.4    Pike, R.N.5    Prochazka, V.6    Kiefer, M.C.7    Travis, J.8    Barr, P.J.9
  • 20
    • 0028840005 scopus 로고
    • Molecular cloning and structural characterization of the Arg-gingipain proteinase of Porphyromonas gingivalis
    • Pavloff N, Potempa J, Pike RN, Prochazka V, Kiefer MC, Travis J, Barr PJ. Molecular cloning and structural characterization of the Arg-gingipain proteinase of Porphyromonas gingivalis. J Biol Chem 1995: 270: 1007-1010.
    • (1995) J Biol Chem , vol.270 , pp. 1007-1010
    • Pavloff, N.1    Potempa, J.2    Pike, R.N.3    Prochazka, V.4    Kiefer, M.C.5    Travis, J.6    Barr, P.J.7
  • 21
    • 0028013159 scopus 로고
    • Lysine- and arginine-specific proteinases from Porphyromonas gingivalis
    • Pike R, McGraw W, Potempa J, Travis J. Lysine- and arginine-specific proteinases from Porphyromonas gingivalis. J Biol Chem 1994: 269: 406-411.
    • (1994) J Biol Chem , vol.269 , pp. 406-411
    • Pike, R.1    McGraw, W.2    Potempa, J.3    Travis, J.4
  • 22
    • 0029913412 scopus 로고    scopus 로고
    • Characterization of the binding activities of proteinase-adhesin complexes from Porphyromonas gingivalis
    • Pike R, Potempa J, McGraw W, Coetzer THT, Travis J. Characterization of the binding activities of proteinase-adhesin complexes from Porphyromonas gingivalis. J Bacteriol 1996: 178: 2876-2882.
    • (1996) J Bacteriol , vol.178 , pp. 2876-2882
    • Pike, R.1    Potempa, J.2    McGraw, W.3    Coetzer, T.H.T.4    Travis, J.5
  • 24
    • 0023792719 scopus 로고
    • Genetic mechanisms of bacterial antigenic variation
    • Siefert HS, So M. Genetic mechanisms of bacterial antigenic variation. Microbiol Rev 1988: 52: 327-336.
    • (1988) Microbiol Rev , vol.52 , pp. 327-336
    • Siefert, H.S.1    So, M.2
  • 25
    • 0031800218 scopus 로고    scopus 로고
    • Characterisation of a second cell-associated Arg-specific cysteine proteinase of Porphyromonas gingivalis and identification of an adhesin binding motif involved in association of the prtR and prtK proteinases and adhesins into large complexes
    • Slakeski N, Bhogal PS, O'Brien-Simpson NM, Reynolds EC. Characterisation of a second cell-associated Arg-specific cysteine proteinase of Porphyromonas gingivalis and identification of an adhesin binding motif involved in association of the prtR and prtK proteinases and adhesins into large complexes. Microbiology 1998: 144: 1583-1592.
    • (1998) Microbiology , vol.144 , pp. 1583-1592
    • Slakeski, N.1    Bhogal, P.S.2    O'Brien-Simpson, N.M.3    Reynolds, E.C.4
  • 26
    • 0030601241 scopus 로고    scopus 로고
    • Characterization of a Porphyromonas gingivalis gene prtR that encodes an arginine-specific thiol proteinase and multiple adhesins
    • Slakeski N, Cleal SM, Reynolds EC. Characterization of a Porphyromonas gingivalis gene prtR that encodes an arginine-specific thiol proteinase and multiple adhesins. Biochem Biophys Res Commun 1996: 224: 605-610.
    • (1996) Biochem Biophys Res Commun , vol.224 , pp. 605-610
    • Slakeski, N.1    Cleal, S.M.2    Reynolds, E.C.3
  • 27
    • 0002230981 scopus 로고
    • Importance of black pigmented bacteroides in human periodontal disease
    • Genco RJ, Merganhagan SE, ed. Washington, DC: Am Soc Microbiol.
    • Slots J. Importance of black pigmented Bacteroides in human periodontal disease. In: Genco RJ, Merganhagan SE, ed. Host-parasite interactions in periodontal diseases. Washington, DC: Am Soc Microbiol. 1982: 27-45.
    • (1982) Host-parasite Interactions in Periodontal Diseases , pp. 27-45
    • Slots, J.1
  • 28
    • 0026847143 scopus 로고
    • The bacterial etiology of destructive periodontal disease: Current concepts
    • Socransky SS, Haffajee AD. The bacterial etiology of destructive periodontal disease: current concepts. J Periodontol 1992: 63: 322-331.
    • (1992) J Periodontol , vol.63 , pp. 322-331
    • Socransky, S.S.1    Haffajee, A.D.2
  • 29
    • 0026647913 scopus 로고
    • Gene conversion in Neisseria gonorrhoeae: Evidence for its role in pilus antigenic variation
    • Zhang QY, DeRyckere D, Lauer P, Koomey M. Gene conversion in Neisseria gonorrhoeae: evidence for its role in pilus antigenic variation. Proc Natl Acad Sci U S A 1992: 89: 5366-5370.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 5366-5370
    • Zhang, Q.Y.1    DeRyckere, D.2    Lauer, P.3    Koomey, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.