Functional constraints and frequency of deleterious mutations in noncoding DNA of rodents

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 23, 2003, Pages 13402-13406

  Keightley, Peter D ^a   Gaffney, Daniel J ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Intergenic DNA; Intron; Selective constraints

Indexed keywords

DNA; NUCLEOTIDE; SPACER DNA;

AMINO ACID SUBSTITUTION; ARTICLE; CONTROLLED STUDY; DELETION MUTANT; DNA SEQUENCE; GENE FREQUENCY; GENE SEQUENCE; GENETIC CODE; GENETIC SELECTION; GENETIC VARIABILITY; GENOME ANALYSIS; INTRON; MOUSE; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; QUANTITATIVE GENETICS; RAT; RNA TRANSLATION;

ANIMALS; CPG ISLANDS; DIPLOIDY; DNA; EVOLUTION, MOLECULAR; GENOME; INTRONS; MICE; MICROSATELLITE REPEATS; MODELS, STATISTICAL; MONTE CARLO METHOD; MUTATION; POINT MUTATION; RATS;

MAMMALIA; RODENTIA; VERTEBRATA;

EID: 0344824015     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.2233252100     Document Type: Article

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