CYPIAI and CYP2D6 polymorphism and risk of lung cancer in a North Indian population

Biomarkers

Volumn 8, Issue 5, 2003, Pages 415-428

  Sobti, R C ^a   Sharma, S ^a   Joshi, A ^a   Jindal, S K ^b   Janmeja, A ^c  

^a PANJAB UNIVERSITY   (India)

^b POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH   (India)

^c GOVERNMENT MEDICAL COLLEGE AND HOSPITAL   (India)

Author keywords

CYP1A1; CYP2D6; Genotypes; Lung cancer; Odds ratio; Polymorphism

Indexed keywords

CYTOCHROME P450 1A1; CYTOCHROME P450 2D6; DEBRISOQUINE; DEBRISOQUINE 4 HYDROXYLASE;

ADULT; ALLELE; ARTICLE; CANCER RISK; CASE CONTROL STUDY; CIGARETTE SMOKING; CONTROLLED STUDY; FEMALE; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HETEROZYGOSITY; HUMAN; INDIA; LUNG CANCER; LUNG CARCINOGENESIS; LUNG SMALL CELL CANCER; MAJOR CLINICAL STUDY; MALE; METABOLISM; POLYMERASE CHAIN REACTION; POPULATION RESEARCH; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SQUAMOUS CELL CARCINOMA; CONFIDENCE INTERVAL; GENETICS; LUNG TUMOR; RISK; RISK FACTOR; SMALL CELL CARCINOMA; SMOKING;

ALLELES; CARCINOMA, SMALL CELL; CARCINOMA, SQUAMOUS CELL; CASE-CONTROL STUDIES; CONFIDENCE INTERVALS; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP2D6; GENOTYPE; HUMANS; INDIA; LUNG NEOPLASMS; ODDS RATIO; POLYMORPHISM, GENETIC; RISK FACTORS; SMOKING;

EID: 0344668499     PISSN: 1354750X     EISSN: None     Source Type: Journal    
DOI: 10.1080/13547500310001619860     Document Type: Article

References (35)

1. Agundez, J. A., Gallardo, L., Ledesma, M. C., Lozano, L., Rodriguez-Lescure, A., Pontes, J.C., Iglesias-Moreno, M. C., Poch, J., Ladero, J. M. and Benitez, J. 2001, Functionally active duplications of the cyp2d6 gene are more prevalent among larynx and lung cancer patients. Oncology, 61, 59-63.
2. Cascorbi, I., Brockmoller, J. and Roots., I. 1996, A C4887A polymorphism in exon7 of human CYP1A1: population frequency, mutation linkages and impact on lung cancer susceptibility. Cancer Research, 56, 4965-4969.
3. Crofts, E., Taioli, J., Trachmann, G. N., Cosma, D., Currie, P., Toniolo, S. and Garte, J. 1993, Functional significance of different human CYP1A1 genotypes. Carcinogenesis, 15, 2961-2963.
4. Daly, A. K., Cholerton, S., Gregory, W. and Idle, J. R. 1993, Metabolic polymorphisms. Pharmacology and Therapeutics, 57, 129-160.
5. Febbo, P. G., Kantoff, P. W., Giovannucci, E., Brown, M., Chang, G., Charles, H. and Stampfer, M. 1998, Debrisoquine hydroxylase (cyp2d6) and prostrate cancer. Cancer Epidemiology, Biomarkers and Prevention, 7, 1075-1078.
6. Field, J. K., Liloglou, T., Xinarianos, G., Prime, P., Fielding, W., Walshaw, J. M. and Turnbull, L. 1999, Genetic alterations in bronchial lavage as a potential marker for individuals with a high risk of developing lung cancer. Cancer Research, 59, 2690-2695.
7. Gao, Y. and Zhang, Q. 1999, Polymorphisms of the gstm1 and cyp2d6 genes associated with susceptibility to lung cancer in Chinese. Mutation Research, 444, 441-449.
8. Hayashi, S., Watanabe, J. and Kawajiri, K. 1992, High susceptibility to lung cancer analyzed in terms of combined genotypes of CYP1A1 and Mu class glutathione-S-transferase genes. Japanese Journal of Cancer Research, 83, 866-870.
9. Hirvonen, A., Pursianen, K. H., Karjalainen, A., Antilla, S. and Vanio, H. 1992, Point mutational MspI and Ile/Val polymorphism closely linked in the CYP1A1 gene; lack of association with susceptibility to lung cancer in a Finnish study population. Cancer Epidemiology, Biomarkers and Prevention, 1, 485-489.
10. Hong, Y. S., Chang, J. H., Kwon, O. J., Ham, Y. A. and Choi, J. J. 1998, Polymorphism of the CYP1A1 and glutathione-S-transferase genes in Korean lung cancer patients. Experimental and Molecular Medicine, 30, 192-198.
11. Kawajiri, K., Nakachi, K., Imai, K., Yoshii, A., Shinoda, N. and Watanabe, J. 1990, Identification of genetically high risk individuals to lung cancer by DNA polymorphisms of cytochrome P4501A1 gene. FEBS Letters, 263, 131-133.
12. Kiyohara, C., Nakanishi, Y., Inutsuka, S., Takayama, K., Hara, N., Tanaka, K., Kono, S. and Hirohata, T. 1998, The relationship between CYP1A1 and aryl hydrocarbon hydroxylase activity and lung cancer in a Japanese population. Pharmacogenetics, 8, 315-323.
13. Laforest, L., Wikman, H., Benhamou, S., Saarikoski, S. T., Bouchardy, C., Hirvonen, A., Dayer, P. and Husgafvel-Pursianen, K. 2000, Cyp2d6 gene polymorphism in Caucasian smokers: lung cancer susceptibility and phenotype-genotype relationships. European Journal of Cancer, 36, 1825-1832.
14. Le Marchand, L., Sivaraman, L., Pierce, L., Seifried, A., Lum, A., Wilkens, L. R. and Lau, A. F. 1998, Association of CYP1A1, GSTM1, and CYP2E1 polymorphisms with lung cancer suggest cell type specificities to tobacco carcinogens. Cancer Research, 58, 4858-4863.
15. Nakachi, K., Imai, K., Hayashi, S., Watanabe, J. and Kawajiri, K. 1991, Genetic susceptibility to squamous cell carcinoma of the lung in relation to tobacco smoking dose. Cancer Research, 51, 5177-5180.
16. Nakachi, K., Imai, K., Hayashi, S. and Kawajiri, K. 1993, Polymorphisms of the CYP1A1 and glutathione-S-transferase genes associate with susceptibility to lung cancer in relation to cigarette dose in Japanese population. Cancer Research, 53, 2994-2998.
17. Nakachi, K., Hayashi, S., Kawajiri, F. K. and Imai, K. 1995, Association of cigarette smoking and CYP1A1 polymorphism with adenocarcinoma of the lung by grades of differentiation. Carcinogenesis, 16, 2209-2213.
18. Nerbert, D. W. 1991, Role of genetics and drug metabolism in human cancer risks. Mutation Research, 247, 67-281.
19. Okada, T., Kawashima, K., Fukishi, S., Minakuchi, T. and Nishimura, S. 1994, Association between a cytochrome P450 CYP1A1 genotype and incidence of lung cancer. Pharmacogenetics, 4, 333-340.
20. Quinones, L., Lucas, D., Godoy, J., Caceres, D., Berthou, F., Varela, N., Lee, K., Acevedo, C., Martinez, L., Aguilera, A. M. and Gil, L. 2001, CYP1A1, CYP2E1 and GSTM1 genetic polymorphisms. The effect of single and combined genotypes on lung cancer susceptibility in Chilean people. Cancer Letters, 174, 35-4.
21. Rannug, A., Alexadrie, A. K., Persson, I. and Ingelman-Sundberg, M. 1995, Genetic polymorphism of cytochromes P450 1a1, 2d6 and 2e1: regulation and toxicological significance. Journal of Occupational and Environmental Medicine, 37, 25-36.
22. Roots, I., Brockmoller, J., Drakoulis, N. and Loddenkemper, R. 1992, Mutant genes of cytochrome P-450II d6, glutathione-S-transferase class Mu and arylamine N-acetyl transferase in lung cancer patients. Clinical Investigation, 70, 307-319.
23. Shaw, G. L., Falk, R. T., Frame, J. N., Weiffenbach, B., Nesbitt, J. C., Pass, H. I., Caporaso, N. E., Moir, D. T. and Tucker, M. A. 1998, Genetic polymorphism of cyp2d6 and lung cancer risk. Cancer Epidemiology, Biomarkers and Prevention, 7, 215-219.
24. Shields, P. G., Caporaso, N. E., Falk, R. I., Sugimura, H., Trivers, G. E., Trump, B. F., Hoover, R. N., Weston, A. and Harris, C. C. 1993, Lung cancer, race and a CYP1A1 genetic polymorphism. Cancer Epidemiology. Biomarkers and Prevention, 2, 581-485.
25. Sivaraman, L., Leatham, M. P., Yee, J., Wilkens, R., Lau, L. A. F. and Le Marchand, L. 1994, CYP1A1 genetic polymorphisms and in situ colorectal cancer. Cancer Research, 54, 3692-3695.
26. Song, N., Tan, W., Xing, D. and Lin., D. 2001, CYP1A1 polymorphism and risk to lung cancer in relation to tobacco smoking: a case-control study in China. Carcinogenesis, 22, 11-16.
27. Sreelekha, K., Ramadas, M., Pandey, G., Thomas, K. R., Nalinakumari, M. and Pillai, R. 2001, Genetic polymorphism of CYP1A1, GSTM1 and GSTT1 genes in Indian oral cancer. Oral Oncology, 37, 593-598.
28. Strauss, G. M. 1997, Measuring effectiveness of lung cancer screening: from consensus to controversy and back. Chest, 112 (Supplement 4), 216S-228S.
29. Stucker, I., Cosme, J., Laurent, P., Cenee, S., Beaune, P. and Bignon, J. 1995, cyp2d6 genotype and lung cancer risk according to histologic type and tobacco exposure. Carcinogenesis, 16, 2759-2764.
30. Sugimura, H., Wakai, K., Genka, K., Nagura, K., Igarashi, H., Nagayama, H., Ohkawa, A., Baba, S., Morris, B. J., Tsugane, S., Ohno, Y., Gao, C., Li, Z., Takezaki, T., Tajima, K. and Iwamasa, T. 1998, Association of Ile-462-Val (exon 7) polymorphism of cytochrome P4501a1 with lung cancer in the Asian population: further evidence from a case-control study in Okinawa. Cancer Epidemiology, Biomarkers and Prevention, 7, 413-417.
31. Tefre, T., Ryberg, D., Haugen, A., Nerbet, D. W., Skaug, V. and Brogger, A. 1991, Human CYP1A1 gene: lack of association between the MspI restriction fragment length polymorphism and incidence of lung cancer in a Norwegian population. Pharmacogenetics, 1, 20-25.
32. Wilkinson, G. R., Guengerich, F. P. and Branch, R. A. 1989, Genetic polymorphism of the S-mephenytoin metabolism in humans. Journal of Biological Chemistry, 269, 15419-15422.
33. Wolf, C. R., Smithy, C. A. D., Gough, A. C., Moss, J. E., Vallis, K. A., Howard, G., Carey, F. J., Mills, K., McNee, W. and Carmicheal, J. 1992, Relationship between the debrisoquine hydroxylase polymorphism and cancer susceptibility. Carcinogenesis, 13, 1035-1038.
34. Xu, X., Kelsey, K. T., Wiencke, J. K., Wain, J. C. and Christiani, D. C. 1996, Cytochrome P450 CYP1A1 MspI polymorphism and lung cancer susceptibility. Cancer Epidemiology, Biomarkers and Prevention, 5, 687-692.
35. Zhang, Z. Y., Fasco, M. J., Huang, L., Guengerich, P. and Kaminsky, L. S. 1996, Characterization of purified human recombinant cytochrome P4501A1-Ile462 and Val462: assessment of a role for the rare allele in carcinogensis. Cancer Research, 56, 3926-3933.