Slow death in the leopard frog Rana pipiens: Neurotransmitters and anoxia tolerance

Journal of Experimental Biology

Volumn 206, Issue 22, 2003, Pages 4021-4028

  Milton, Sarah L ^a   Manuel, Liscia ^a   Lutz, Peter L ^a  

^a FLORIDA ATLANTIC UNIVERSITY   (United States)

Author keywords

Anoxia; Dopamine; Excitatory amino acid; Frog; Rana pipiens; Slow death

Indexed keywords

AMINO ACID; DOPAMINE;

ANALYSIS OF VARIANCE; ANIMAL; ARTICLE; BRAIN; BRAIN HYPOXIA; COMPARATIVE STUDY; FROG; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLISM; MICRODIALYSIS; PATHOPHYSIOLOGY; PHYSIOLOGY; TIME;

AMINO ACIDS; ANALYSIS OF VARIANCE; ANIMALS; BRAIN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOPAMINE; HYPOXIA, BRAIN; MICRODIALYSIS; RANA PIPIENS; TIME FACTORS;

ANIMALIA; ANURA; MAMMALIA; PANTHERA PARDUS; RANA PIPIENS; RANA TEMPORARIA; TESTUDINES; VERTEBRATA;

EID: 0344584519     PISSN: 00220949     EISSN: None     Source Type: Journal    
DOI: 10.1242/jeb.00647     Document Type: Article

References (52)

1. al-Bekairi, A. M. (1989). Effect of hypoxia and/or cold stress on plasma and brain amino acids in rat. Res. Commun. Chem. Pathol. Pharmacol. 64, 287-297.
2. Baker, A. J., Zornow, M. H., Scheller, M. S., Yaksh, T. L., Skilling, S. R., Smullin, D. H., Larson, A. A. and Kuczenski, R. (1991). Changes in extracellular concentrations of glutamate, aspartate, glycine, dopamine, serotonin, and dopamine metabolites after transient global ischemia in the rabbit brain. J. Neurochem. 57, 1370-1379.
3. 31P-N.M.R. study. Biochem. J. 291, 915-919.
4. Bickler, P. E., Donohoe, P. H. and Buck, L. T. (2002). Molecular adaptations for survival during anoxia: lessons from lower vertebrates. Neuroscientist 8, 234-242.
5. Brooks, S. P. J. and Storey, K. B. (1989). Regulation of glycolytic enzymes during anoxia in the turtle Pseudemys scripta. Am. J. Physiol. 257, R278-R283.
6. Choi, D. W. (1992). Excitotoxic cell death. J. Neurobiol. 23, 1261-1276.
7. Donohoe, P. H. and Boutilier, R. G. (1998). The protective effects of metabolic rate depression in hypoxic cold submerged frogs. Resp. Pysiol. 111, 325-336.
8. Donohoe, P. W., West, T. G. and Boutilier, R. G. (1998). Respiratory, metabolic, and acid-base correlates of aerobic metabolic rate reduction in overwintering frogs. Am. J. Physiol. 274, R704-R710.
9. Erecinska, M., Nelson, D., Wilson, D. F., and Silver, I. A. (1984). Neurotransmitter amino acids in the CNS. I. Regional changes in amino acid levels in rat brain during ischemia and reperfusion. Brain Res. 304, 9-22.
10. Fabricius, M., Jensen, L. H. and Lauritzen, M. (1993). Microdialysis of interstitial amino acids during spreading depression and anoxic depolarization in rat neocortex. Brain Res. 612, 61-69.
11. Globus, M. Y.-T., Busto, R., Dietrich, W. D., Martinez, E., Valdes, I. and Ginsberg, M. D. (1988). Effect of ischemia on the in vivo release of striatal dopamine, glutamate and alpha-amino-butyric-acid studied by intracerebral microdialysis. J. Neurochem. 51, 1455-1464.
12. Globus, M. Y.-T., Ginsberg, M. D., Harik, S. I., Busto, R. and Dietrich, W. D. (1987). Role of dopamine in ischemic striatal injury: metabolic evidence. Neurol. 37, 1712-1719.
13. Goda, H., Ooboshi, H., Nakane, H., Ibayasi, S., Sadoshima, S. and Fujishima, M. (1998). Modulation of ischemia-evoked release of excitatory and inhibitory amino acids by adenosine A1 receptor agonist. Eur. J. Pharmacol. 357, 149-155.
14. Hermes-Lima, M. and Storey, K. B. (1996). Relationship between anoxia exposure and antioxidant status in the frog Rana pipiens. Am. J. Physiol. 271, R918-R925.
15. Hochachka, P. W. (1980). Living Without Oxygen. Cambridge: Harvard University Press. 181 pp.
16. Hochachka, P. W. and Somero, G. N. (2002). Biochemical Adaptation. New York: Oxford University Press.
17. Hoyt, K. R., Reynolds, I. J. and Hastings, G. (1997). Mechanisms of dopamine-induced cell death in cultured rat forebrain neurons, interactions with and differences from glutamate-induced cell death. Exp. Neurol. 143, 269-281.
18. Huang, C. C., Najevardi, N. S., Tammela, O., Pastruszko, A., Delivoria-Papadopoulos, M. and Wilson, D. F. (1994). Relationship of extracellular dopamine in striatum of newborn piglets to cortical oxygen pressure. Neurochem. Res. 19, 6499-6655.
19. Hylland, P. and Nilsson, G. E. (1999). Extracellular levels of amino acid neurotransmitters during anoxia and forced energy deficiency in crucian carp brain. Brain Res. 823, 49-58.
20. Hylland, P., Nilsson, G. E. and Lutz, P. L. (1994). Time course of anoxia induced increase in cerebral blood flow rate in turtles: evidence for a role of adenosine. J. Cereb. Blood Flow Metab. 14, 877-881.
21. + in rainbow trout thalamus. Am. J. Physiol. 269, R1077-R1084.
22. Johns, L., Sinclair, A. J. and Davies, J. A. (2000). Hypoxia/ hypoglycemia-induced amino acid release is decreased in vitro by preconditioning. Biochem. Biophys. Res. Commun. 276, 134-136.
23. Jones, M. G. and Szatkowski, M. S. (1995). The role of glycine in anoxia/aglycaemia-induced potentiation of N-methyl-D-aspartate receptor-mediated postsynaptic potentials in the rat hippocampus. Neurosci. Lett. 201, 227-230.
24. Kalivas, P. W. and Duffy, P. (1997). Dopamine regulation of extracellular glutamate in the nucleus accumbens. Brain Res. 761, 173-177.
25. Knickerbocker, D. L. and Lutz, P. L. (2001). Slow ATP loss and the defense of ion homeostasis in the anoxic frog brain. J. Exp. Biol. 204, 3547-3551.
26. Li, X., Wallin, C., Weber, S. G. and Sandberg, M. (1999). Net efflux of cysteine, glutathione, and related metabolites from rat hippocampal slices during oxygen/glucose deprivation: dependence on gamma-glumly transpeptidase. Bran Res. 815, 81-88.
27. Lutz, P. L. and Reiners, R. (1997). Survival of energy failure in the anoxic frog brain: delayed release of glutamate. J. Exp. Biol. 200, 2913-2917.
28. Lutz, P. L., Nilsson, G. E. and Prentice, H. (2003). The Brain Without Oxygen: Causes of Failure and Molecular Mechanisms for Survival. 3rd edn. Boston: Kluwer Academic Publishers.
29. Lutz, P. L., Ortiz, M., Leone-Kabler, S. and Schulman, A. (1994). Regional changes in amino acid levels of the neonate rat brain during anoxia and recovery. Neurochem. Res. 19, 1283-1287.
30. McLaughlin, B. A., Nelson, D., Erecinska, M. and Chesselet, M. F. (1998). Toxicity of dopamine to striatal neurons in vitro and potentiation of cell death by a mitochondrial inhibitor. J. Neurochem. 70, 2406-2415.
31. Milton, S. L. and Lutz, P. L. (1998). Low extracellular dopamine levels are maintained in the anoxic turtle (Trachemys scripta) striatum. J. Cereb. Blood Flow Metab. 18, 803-807.
32. Milton, S. L., Thompson, J. W. and Lutz, P. L. (2002). Mechanisms for maintaining extracellular glutamate levels in the anoxic turtle striatum. Am. J. Physiol. Reg. Integr. Comp. Physiol. 282, R1317-R1323.
33. Morari, M., Marti, M., Sbrenna, S., Fuxe, K., Bianchi, C. and Beani, L. (1998). Reciprocal dopamine-glutamate modulation of release in the basal ganglia. Neurochem. Int. 33, 383-397.
34. Nilsson, G. E. (1990). Long-term anoxia in crucian carp: changes in the levels of amino acid and monoamine neurotransmitters in the brain, catecholamines in chromaffin tissue and liver glycogen. J. Exp. Biol. 150, 295-320.
35. Nilsson, G. E. and Lutz, P. L. (1991). Release of inhibitory neurotransmitters in response to anoxia in turtle brain. Am. J. Physiol. 261, R32-R37.
36. Nilsson, G. E. and Winberg, S. (1993). Changes in the brain levels of GABA and related amino acids in anoxic shore crab (Carcinus maenas). Am. J. Physiol. 264, R733-R737.
37. Nilsson, G. E., Alfaro, A. and Lutz, P. L. (1990). Changes in turtle brain neurotransmitters and related substances during anoxia. Am. J. Physiol. Reg. Integr. Comp. Physiol. 259, R376-R384.
38. Nilsson, G. E., Lutz, P. L., and Jackson, T. L. (1991). Neurotransmitters and anoxic survival of the brain: A comparison of anoxia-tolerant and anoxia-intolerant vertebrates. Physiol. Zool. 64, 638-652.
39. Nong, Y., Huang, Y. Q., Ju, W., Kalia, L. V., Ahmadian, G., Wang, Y. T. and Salter, M. W. (2003). Glycine binding primes NMDA receptor internalization. Nature 422, 302-307.
40. Perez-Pinzon, M. A., Nilsson, G. E. and Lutz, P. L. (1993). Relationship between ion gradients and neurotransmitter release in the newborn rat striatum during anoxia. Brain Res. 602, 228-233.
41. Remblier, C., Pontchamaud, R., Tallineaie, C., Piriou, A. and Huguet, F. (1999). Lactic acid induced increase of extracellular dopamine measured by microdialysis in rat striatum: evidence for glutamatergic and oxidative mechanisms. Brain Res. 837, 22-28.
42. Rothman, S. M. and Olney, J. W. (1986). Glutamate and the pathophysiology of hypoxic-ischemic brain damage. Ann. Neurol. 19, 105-111.
43. Santos, M. S., Moreno, A. J. and Carvalho, A. P. (1996). Relationships between ATP depletion, membrane potential, and the release of neurotransmitters in rat nerve terminals. An in vitro study under conditions that mimic anoxia, hypoglycemia, and ischemia. Stroke 27, 941-950.
44. Saransaari, P. and Oja, S. S. (1998). Release of endogenous glutamate, aspartate, GABA, and taurine from hippocampal slices from adult and developing mice under cell-damaging conditions. Neurochem. Res. 23, 563-570.
45. Saransaari, P. and Oja, S. S. (2001). Characteristics of hippocampal glycine release in cell-damaging conditions in the adult and developing mouse. Neurochem. Res. 26, 845-852.
46. Stokes, A. H., Hastings, T. G. and Vrana, K. E. (1999). Cytotoxic and genotoxic potential of dopamine. J. Neurosci. Res. 55, 659-665.
47. Tan, W. K., Williams, C. E., During, M. J., Mallard, C. E., Gunning, M. I., Gunn, A. J. and Gluckman, P. D. (1996). Accumulation of cytotoxins during development of seizures and edema after hypoxic-ischemic injury during late gestation fetal sheep. Pediatr. Res. 39, 791-797.
48. Wallin, C., Puka-Sundvall, M., Hagberg, H., Weber, S. G., and Sandberg, M. (2000). Alterations in glutathione and amino acid concentrations after hypoxia-ischemia in the immature rat brain. Brain Res. Dev. Brain Res. 125, 51-60.
49. West, T. G. and Boutilier, R. G. (1998). Metabolic suppression in anoxic frog muscle. J. Comp. Physiol. B 168, 273-280.
50. Wheeler, M. D., Ikejema, K., Enomoto, N., Stacklewitz, R. F., Seabra, V., Zhong, Z., Yin, M., Schemmer, P., Rose, M. L., Rusyn, I., Bradford, B. and Thurman, R. G. (1999). Glycine: a new anti-inflammatory immunonutrient. Cell. Mol. Life Sci. 56, 843-856.
51. Young, R. S., During, M. J., Donnelly, D. F., Aquila, W. J., Perry, V. L. and Haddad, G. G. (1993). Effect of anoxia on excitatory amino acids in brain slices of rats and turtles: in vitro microdialysis. Am. J. Physiol. 264, R716-R719.
52. Zeitlow, R., Sinclair, S. R., Schwiening, C. J., Dunnett, S. B. and Fawcett, J. W. (2002). The release of excitatory amino acids, dopamine, and potassium following transplantation of embryonic mesencephalic dopaminergic grafts to the rat striatum, and their effects on dopaminergic neuronal survival in vitro. Cell Transplant 11, 637-652.