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Volumn 9, Issue 3-4, 1998, Pages 205-211

Nuclear import and export of proteins: The molecular basis for intracellular signaling

Author keywords

Nuclear export signal (NES); Nuclear localization signal (NLS); Nuclear pore targeting complex; Ran; Stat

Indexed keywords

NUCLEAR PROTEIN; STAT1 PROTEIN;

EID: 0344572679     PISSN: 13596101     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1359-6101(98)00012-4     Document Type: Short Survey
Times cited : (21)

References (61)
  • 1
    • 0029199471 scopus 로고
    • Toward a molecular understanding of the structure and function of the nuclear pore complex
    • Pante N, Aebi U. Toward a molecular understanding of the structure and function of the nuclear pore complex. Int Rev Cytol 1995, 162, 225-255.
    • (1995) Int Rev Cytol , vol.162 , pp. 225-255
    • Pante, N.1    Aebi, U.2
  • 2
    • 0027989786 scopus 로고
    • Pores for thought: Nuclear pore complex proteins
    • Rout MP, Wente SR. Pores for thought: nuclear pore complex proteins. Trends Cell Biol 1994, 4, 357-365.
    • (1994) Trends Cell Biol , vol.4 , pp. 357-365
    • Rout, M.P.1    Wente, S.R.2
  • 3
    • 0021269089 scopus 로고
    • Sequence requirements for nuclear location of simian virus 40 large-T antigen
    • Kalderon D, Richardson WD, Markham AF, Smith AE. Sequence requirements for nuclear location of simian virus 40 large-T antigen. Nature 1984, 311, 33-38.
    • (1984) Nature , vol.311 , pp. 33-38
    • Kalderon, D.1    Richardson, W.D.2    Markham, A.F.3    Smith, A.E.4
  • 5
    • 0023262677 scopus 로고
    • Synthetic peptides containing a region of SV40 large T-antigen involved in nuclear localization direct the transport of proteins into the nucleus
    • Yoneda Y, Arioka T, Imamoto-Sonobe N, Sugawa H, Shimonishi Y, Uchida T. Synthetic peptides containing a region of SV40 large T-antigen involved in nuclear localization direct the transport of proteins into the nucleus. Exp Cell Res 1987, 170, 439-452.
    • (1987) Exp Cell Res , vol.170 , pp. 439-452
    • Yoneda, Y.1    Arioka, T.2    Imamoto-Sonobe, N.3    Sugawa, H.4    Shimonishi, Y.5    Uchida, T.6
  • 6
    • 0009605066 scopus 로고
    • Nuclear targeting sequences - A consensus?
    • Dingwall C, Laskey RA. Nuclear targeting sequences - a consensus? Trends Cell Biol 1991, 4, 357-365.
    • (1991) Trends Cell Biol , vol.4 , pp. 357-365
    • Dingwall, C.1    Laskey, R.A.2
  • 7
    • 0025083331 scopus 로고
    • Nuclear protein import in permeabilized mammalian cells requires soluble cytoplasmic factors
    • Adam SA, Sterne-Marr R, Gerace L. Nuclear protein import in permeabilized mammalian cells requires soluble cytoplasmic factors. J. Cell Biol 1990, 111, 807-816.
    • (1990) J. Cell Biol , vol.111 , pp. 807-816
    • Adam, S.A.1    Sterne-Marr, R.2    Gerace, L.3
  • 8
    • 0028970112 scopus 로고
    • A karyophilic protein forms a stable complex with cytoplasmic component prior to nuclear pore binding
    • Imamoto N, Tachibana T, Matsubae M, Yoneda Y. A karyophilic protein forms a stable complex with cytoplasmic component prior to nuclear pore binding. J Biol Chem 1995, 270, 8559-8565.
    • (1995) J Biol Chem , vol.270 , pp. 8559-8565
    • Imamoto, N.1    Tachibana, T.2    Matsubae, M.3    Yoneda, Y.4
  • 9
    • 0027937653 scopus 로고
    • Isolation of a protein that is essential for the first step of the nuclear protein import
    • Görlich D, Prehn S, Laskey RA, Hartmann E. Isolation of a protein that is essential for the first step of the nuclear protein import. Cell 1994, 79, 767-778.
    • (1994) Cell , vol.79 , pp. 767-778
    • Görlich, D.1    Prehn, S.2    Laskey, R.A.3    Hartmann, E.4
  • 11
    • 0028962511 scopus 로고
    • Previously identified protein of uncertain function is karyopherin a and together with karyopherin β docks import substrate at nuclear pore complex
    • Moroianu J, Blobel G, Radu A. Previously identified protein of uncertain function is karyopherin a and together with karyopherin β docks import substrate at nuclear pore complex. Proc Natl Acad Sci USA 1995, 92, 2008-2011.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 2008-2011
    • Moroianu, J.1    Blobel, G.2    Radu, A.3
  • 12
    • 0028266975 scopus 로고
    • A repeating amino acid motif shared by proteins with diverse cellular roles
    • Peifer M, Berg S, Reynolds AB. A repeating amino acid motif shared by proteins with diverse cellular roles. Cell 1994, 76, 789-791.
    • (1994) Cell , vol.76 , pp. 789-791
    • Peifer, M.1    Berg, S.2    Reynolds, A.B.3
  • 13
    • 0029278621 scopus 로고
    • Two different subunits of importin cooperates to recognize nuclear localization signal and bind them to the nuclear envelope
    • Görlich D, Kostka S, Kraft R, Dingwall C, Laskey RA, Hartmann E, Prehn S. Two different subunits of importin cooperates to recognize nuclear localization signal and bind them to the nuclear envelope. Curr Biol 1995, 5, 383-392.
    • (1995) Curr Biol , vol.5 , pp. 383-392
    • Görlich, D.1    Kostka, S.2    Kraft, R.3    Dingwall, C.4    Laskey, R.A.5    Hartmann, E.6    Prehn, S.7
  • 15
    • 0028950991 scopus 로고
    • Identification of a protein complex that is required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins
    • Radu A, Blobel G, Moore MS. Identification of a protein complex that is required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins. Proc Natl Acad Sci USA 1995, 92, 1769-1773.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 1769-1773
    • Radu, A.1    Blobel, G.2    Moore, M.S.3
  • 16
    • 0029115837 scopus 로고
    • Sequence and characterization of cytoplasmic nuclear protein import factor p97
    • Chi NC, Adam EJM, Adam SA. Sequence and characterization of cytoplasmic nuclear protein import factor p97. J Cell Biol 1995, 130, 265-274.
    • (1995) J Cell Biol , vol.130 , pp. 265-274
    • Chi, N.C.1    Adam, E.J.M.2    Adam, S.A.3
  • 17
    • 0027376308 scopus 로고
    • The GTP-binding protein Ran/TC4 is required for protein import into the nucleus
    • Moore MS. Blobel G. The GTP-binding protein Ran/TC4 is required for protein import into the nucleus. Nature 1993, 365, 661-663.
    • (1993) Nature , vol.365 , pp. 661-663
    • Moore, M.S.1    Blobel, G.2
  • 18
    • 0027714921 scopus 로고
    • Inhibition of nuclear import by nonhydrolyzable analogues of GTP and identification of the small GTPase Ran/TC4 as an essential transport factor
    • Melchior FB, Paschal J, Evans J, Gerace L. Inhibition of nuclear import by nonhydrolyzable analogues of GTP and identification of the small GTPase Ran/TC4 as an essential transport factor. J Cell Biol 1993, 123, 1649-1659.
    • (1993) J Cell Biol , vol.123 , pp. 1649-1659
    • Melchior, F.B.1    Paschal, J.2    Evans, J.3    Gerace, L.4
  • 19
    • 0028170744 scopus 로고
    • Purification of Ran-interacting protein that is required for protein import into the nucleus
    • Moore MS, Blobel G. Purification of Ran-interacting protein that is required for protein import into the nucleus. Proc Natl Acad Sci USA 1994, 91, 10,212-10,216.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 10212-10216
    • Moore, M.S.1    Blobel, G.2
  • 20
    • 0029027836 scopus 로고
    • Identification of NTF2; a cytosolic factor for nuclear protein import that interacts with nuclear pore complex protein p62
    • Paschal BM, and Gerace L. Identification of NTF2; a cytosolic factor for nuclear protein import that interacts with nuclear pore complex protein p62. J Cell Biol 1995, 129, 925-937.
    • (1995) J Cell Biol , vol.129 , pp. 925-937
    • Paschal, B.M.1    Gerace, L.2
  • 21
    • 0028832520 scopus 로고
    • GTP hydrolysis by Ran occurs at the nuclear pore complex in an early step of protein import
    • Melchior FB, Guan T, Yokoyama N, Nishimoto T, Gerace L. GTP hydrolysis by Ran occurs at the nuclear pore complex in an early step of protein import. J Cell Biol 1995, 131, 571-581.
    • (1995) J Cell Biol , vol.131 , pp. 571-581
    • Melchior, F.B.1    Guan, T.2    Yokoyama, N.3    Nishimoto, T.4    Gerace, L.5
  • 22
    • 0029944335 scopus 로고    scopus 로고
    • Ran/TC4 mutants identify a common requirement for snRNP and protein import into the nucleus
    • Palacios I, Weis K, Klebe C, Mattaj IW, Dingwall C. Ran/TC4 mutants identify a common requirement for snRNP and protein import into the nucleus. J Cell Biol 1996, 113, 485-494.
    • (1996) J Cell Biol , vol.113 , pp. 485-494
    • Palacios, I.1    Weis, K.2    Klebe, C.3    Mattaj, I.W.4    Dingwall, C.5
  • 23
    • 0031005268 scopus 로고    scopus 로고
    • From nucleoporins to nuclear pore complexes
    • Doye V, Hurt E. From nucleoporins to nuclear pore complexes. Curr Opin Cell Biol 1997, 9, 401-411.
    • (1997) Curr Opin Cell Biol , vol.9 , pp. 401-411
    • Doye, V.1    Hurt, E.2
  • 24
    • 0028930155 scopus 로고
    • A nuclear localization domain in the hnRNP Al protein
    • Siomi H, Dreyfuss G. A nuclear localization domain in the hnRNP Al protein. J. Cell Biol 1995, 129, 551-559.
    • (1995) J. Cell Biol , vol.129 , pp. 551-559
    • Siomi, H.1    Dreyfuss, G.2
  • 25
    • 0028845313 scopus 로고
    • A nuclear export signal in hnRNP Al: A signal-mediated, temperature-dependent nuclear protein export pathway
    • Michael WM, Choi M, Dreyfuss G. A nuclear export signal in hnRNP Al: a signal-mediated, temperature-dependent nuclear protein export pathway. Cell 1995, 83, 415-422.
    • (1995) Cell , vol.83 , pp. 415-422
    • Michael, W.M.1    Choi, M.2    Dreyfuss, G.3
  • 27
    • 0029025345 scopus 로고
    • Identification of a yeast karyopherin heterodimer that target import of substrate to mammalian nuclear pore complexes
    • Enenkel C, Blobel G, Rexach M. Identification of a yeast karyopherin heterodimer that target import of substrate to mammalian nuclear pore complexes. J Biol Chem 1995, 270, 16,499-16,502.
    • (1995) J Biol Chem , vol.270 , pp. 16499-16502
    • Enenkel, C.1    Blobel, G.2    Rexach, M.3
  • 28
    • 0029845118 scopus 로고    scopus 로고
    • Kap 104p: A karyopherin involved in the nuclear transport messenger RNA binding proteins
    • Aitchison JD, Blobel G, Rout MP. Kap 104p: A karyopherin involved in the nuclear transport messenger RNA binding proteins. Science 1996, 274, 624-627.
    • (1996) Science , vol.274 , pp. 624-627
    • Aitchison, J.D.1    Blobel, G.2    Rout, M.P.3
  • 29
    • 0030722506 scopus 로고    scopus 로고
    • A distinct nuclear import pathway used by ribosomal proteins
    • Rout M, Blobel G, Aitchison D. A distinct nuclear import pathway used by ribosomal proteins. Cell 1997, 89, 715-725.
    • (1997) Cell , vol.89 , pp. 715-725
    • Rout, M.1    Blobel, G.2    Aitchison, D.3
  • 30
    • 1842375738 scopus 로고    scopus 로고
    • Ran-binding protein 5 (RanBP5) is related to the nuclear transport factor importin β but interacts differently with RanBP1
    • Dean R, Schfer W, Zimmermann HP, Mueller L, Görlich D, Prehn S, Postingl H, Bischoff FR. Ran-binding protein 5 (RanBP5) is related to the nuclear transport factor importin β but interacts differently with RanBP1. Mol Cell Biol 1997, 17, 5087-5096.
    • (1997) Mol Cell Biol , vol.17 , pp. 5087-5096
    • Dean, R.1    Schfer, W.2    Zimmermann, H.P.3    Mueller, L.4    Görlich, D.5    Prehn, S.6    Postingl, H.7    Bischoff, F.R.8
  • 31
    • 0030984329 scopus 로고    scopus 로고
    • Cloning and characterization of human karyopherin β3
    • Yaseen NR, and Blobel G. Cloning and characterization of human karyopherin β3. Proc Natl Acad Sci USA 1997, 94, 4451-4456.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 4451-4456
    • Yaseen, N.R.1    Blobel, G.2
  • 32
    • 0027090310 scopus 로고
    • Activation of transcription by IFN-γ: Tyrosine phosphorylation of a 91-kDa DNA binding protein
    • Shuai K, Schindler C, Prezioso VR, Darnell JE, Jr. Activation of transcription by IFN-γ: tyrosine phosphorylation of a 91-kDa DNA binding protein. Science 1992, 258, 1808-1812.
    • (1992) Science , vol.258 , pp. 1808-1812
    • Shuai, K.1    Schindler, C.2    Prezioso, V.R.3    Darnell J.E., Jr.4
  • 33
    • 0027493650 scopus 로고
    • A single phosphotyrosine residue of Stat91 required for gene activation by interferon-y
    • Shuai K, Stark GR, Kerr IM, Darnell JE, Jr. A single phosphotyrosine residue of Stat91 required for gene activation by interferon-y. Science 1993, 261, 1744-1746.
    • (1993) Science , vol.261 , pp. 1744-1746
    • Shuai, K.1    Stark, G.R.2    Kerr, I.M.3    Darnell J.E., Jr.4
  • 34
    • 0028349904 scopus 로고
    • Interferon activation of the transcription factor Stat1 involves dimerization through SH2-phosphotyrosyl peptide interaction
    • Shuai K, Horvath CM, Tsai Huang LH, Qureshi SA, Cowburn D, Darnell JE, Jr. Interferon activation of the transcription factor Stat1 involves dimerization through SH2-phosphotyrosyl peptide interaction. Cell 1994, 76, 821-828.
    • (1994) Cell , vol.76 , pp. 821-828
    • Shuai, K.1    Horvath, C.M.2    Tsai Huang, L.H.3    Qureshi, S.A.4    Cowburn, D.5    Darnell J.E., Jr.6
  • 35
    • 0029117304 scopus 로고
    • Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation
    • Wen Z, Zhong, Z. Darnell JE, Jr. Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation. Cell 1995, 82, 241-250.
    • (1995) Cell , vol.82 , pp. 241-250
    • Wen, Z.1    Zhong, Z.2    Darnell J.E., Jr.3
  • 36
    • 0028234529 scopus 로고
    • Jak-STAT pathway and transcriptional activation in response to IFNs and other extracellular signaling proteins
    • Darnell JE, Jr, Kerr IM, Stark GR. Jak-STAT pathway and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 1994, 264, 1415-1521.
    • (1994) Science , vol.264 , pp. 1415-1521
    • Darnell J.E., Jr.1    Kerr, I.M.2    Stark, G.R.3
  • 37
    • 0028921573 scopus 로고
    • Jaks and Stats in signaling by the cytokine receptor superfamily
    • Ihle JN, Kerr IM. Jaks and Stats in signaling by the cytokine receptor superfamily. Trends Genet 1995, 11, 69-74.
    • (1995) Trends Genet , vol.11 , pp. 69-74
    • Ihle, J.N.1    Kerr, I.M.2
  • 38
    • 0029958032 scopus 로고    scopus 로고
    • Interferon-y dependent nuclear import of Stat1 is mediated by GTPase activity of Ran/TC4
    • Sekimoto T, Nakajima K, Tachibana T, Hirano T, Yoneda Y. Interferon-y dependent nuclear import of Stat1 is mediated by GTPase activity of Ran/TC4. J Biol Chem 1996, 271, 31,017-31,020.
    • (1996) J Biol Chem , vol.271 , pp. 31017-31020
    • Sekimoto, T.1    Nakajima, K.2    Tachibana, T.3    Hirano, T.4    Yoneda, Y.5
  • 39
    • 0029899120 scopus 로고    scopus 로고
    • Evidence using a green fluorescent protein-glucocorticoid receptor chimera that the Ran/TC4 GTPase mediates as essential function independent of nuclear protein import
    • Carey KL, Richards SA, Lounsbury KM, Macara IG. Evidence using a green fluorescent protein-glucocorticoid receptor chimera that the Ran/TC4 GTPase mediates as essential function independent of nuclear protein import. J. Cell Biol 1996, 133, 985-996.
    • (1996) J. Cell Biol , vol.133 , pp. 985-996
    • Carey, K.L.1    Richards, S.A.2    Lounsbury, K.M.3    Macara, I.G.4
  • 40
    • 0030670639 scopus 로고    scopus 로고
    • Extracellular signal-dependent nuclear import of Stat1 is mediated by nuclear pore-targeting complex formation with NPI-1, but not Rch1
    • Sekimoto T, Imamoto N, Nakajima K, Hirano T, Yoneda Y. Extracellular signal-dependent nuclear import of Stat1 is mediated by nuclear pore-targeting complex formation with NPI-1, but not Rch1. EMBO J, 1997, 16, 7067-7077.
    • (1997) EMBO J , vol.16 , pp. 7067-7077
    • Sekimoto, T.1    Imamoto, N.2    Nakajima, K.3    Hirano, T.4    Yoneda, Y.5
  • 41
    • 0028979910 scopus 로고
    • NPI-1, the human homologue of SRP-1, interacts with influenza virus nucleoprotein
    • O'Neill RE, Palese P. NPI-1, the human homologue of SRP-1, interacts with influenza virus nucleoprotein. Virology 1995, 206, 116-125.
    • (1995) Virology , vol.206 , pp. 116-125
    • O'Neill, R.E.1    Palese, P.2
  • 42
    • 0027994484 scopus 로고
    • RAG-1 interacts with the repeated amino acid motif of the human homologue of the yeast protein SRP1
    • Cortes P, Ye Zs, Baltimore D. RAG-1 interacts with the repeated amino acid motif of the human homologue of the yeast protein SRP1. Proc Natl Acad Sci USA 1994, 91, 7633-7637.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 7633-7637
    • Cortes, P.1    Ye, Zs.2    Baltimore, D.3
  • 43
    • 0028239241 scopus 로고
    • Rch-1, a protein that specifically interacts with the RAG-1 recombination activating protein
    • Cuomo CA, Kirch SA, Gyuris J, Brent R, Oettinger MA. Rch-1, a protein that specifically interacts with the RAG-1 recombination activating protein. Proc Natl Acad Sci USA 1994, 91, 6156-6160.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 6156-6160
    • Cuomo, C.A.1    Kirch, S.A.2    Gyuris, J.3    Brent, R.4    Oettinger, M.A.5
  • 44
    • 0028988731 scopus 로고
    • Identification of hSRP1α as a functional receptor for nuclear localization sequence
    • Weis K, Mattaj IW, Lamond AI. Identification of hSRP1α as a functional receptor for nuclear localization sequence. Science 1995, 268, 1049-1051.
    • (1995) Science , vol.268 , pp. 1049-1051
    • Weis, K.1    Mattaj, I.W.2    Lamond, A.I.3
  • 45
    • 0029921174 scopus 로고    scopus 로고
    • A 41 amino acid motif importin α confers binding to importin β and hence transit into the nucleus
    • Görlich D, Henklein P, Laskey RA, Hartmann E. A 41 amino acid motif importin α confers binding to importin β and hence transit into the nucleus. EMBO J 1996, 15, 1810-1817.
    • (1996) EMBO J , vol.15 , pp. 1810-1817
    • Görlich, D.1    Henklein, P.2    Laskey, R.A.3    Hartmann, E.4
  • 46
    • 0030010107 scopus 로고    scopus 로고
    • The conserved amino terminal domain of hSRP1α is essential for nuclear protein import
    • Weis K, Ryder U, Lamond AI. The conserved amino terminal domain of hSRP1α is essential for nuclear protein import. EMBO J 1996, 15, 1818-1825.
    • (1996) EMBO J , vol.15 , pp. 1818-1825
    • Weis, K.1    Ryder, U.2    Lamond, A.I.3
  • 47
    • 0031959356 scopus 로고    scopus 로고
    • Nuclear transport factors: Function, behavior and interaction
    • Imamoto N, Kamei Y, Yoneda Y. Nuclear transport factors: function, behavior and interaction. Eur J Histochem 1998, 42, 9-20.
    • (1998) Eur J Histochem , vol.42 , pp. 9-20
    • Imamoto, N.1    Kamei, Y.2    Yoneda, Y.3
  • 48
    • 0030994992 scopus 로고    scopus 로고
    • Cloning of a cDNA encoding a novel importin α homologue, Qip1: Discrimination of Qip1 and Rch1 from hSrp1 by their ability to interact with DNA helicase Q1/RecQL
    • Seki T, Tada S, Katada T, Enomoto T. Cloning of a cDNA encoding a novel importin α homologue, Qip1: Discrimination of Qip1 and Rch1 from hSrp1 by their ability to interact with DNA helicase Q1/RecQL. Biochem Biophys Res Commun 1997, 234, 48-53.
    • (1997) Biochem Biophys Res Commun , vol.234 , pp. 48-53
    • Seki, T.1    Tada, S.2    Katada, T.3    Enomoto, T.4
  • 49
    • 0030671402 scopus 로고    scopus 로고
    • Differential modes of nuclear localization signal (NLS) recognition by three distinct classes of NLS receptors
    • Miyamoto Y, Imamoto N, Sekimoto T, Tachibana T, Seki T, Tada S, Enomoto T, Yoneda Y. Differential modes of nuclear localization signal (NLS) recognition by three distinct classes of NLS receptors. J Biol Chem 1997, 272, 26,375-26,381.
    • (1997) J Biol Chem , vol.272 , pp. 26375-26381
    • Miyamoto, Y.1    Imamoto, N.2    Sekimoto, T.3    Tachibana, T.4    Seki, T.5    Tada, S.6    Enomoto, T.7    Yoneda, Y.8
  • 50
    • 0030780220 scopus 로고    scopus 로고
    • Identification of novel homologues of mouse importin α, the α subunit of the nuclear pore-targeting complex, and their tissue-specific expression
    • Tsuji L, Takumi T, Imamoto N, Yoneda Y. Identification of novel homologues of mouse importin α, the α subunit of the nuclear pore-targeting complex, and their tissue-specific expression. FEBS Lett 1997, 416, 30-34.
    • (1997) FEBS Lett , vol.416 , pp. 30-34
    • Tsuji, L.1    Takumi, T.2    Imamoto, N.3    Yoneda, Y.4
  • 51
    • 0026490039 scopus 로고
    • Cloning and characterization of SRP1, a suppresser of temperature sensitive RNA polymerase I mutations in Saccharomyces cerevisiae
    • Yano R, Oakes M, Yamaghishi M, Dodd JA, Nomura M. Cloning and characterization of SRP1, a suppresser of temperature sensitive RNA polymerase I mutations in Saccharomyces cerevisiae. Mol Cell Biol 1992, 12, 5640-5651.
    • (1992) Mol Cell Biol , vol.12 , pp. 5640-5651
    • Yano, R.1    Oakes, M.2    Yamaghishi, M.3    Dodd, J.A.4    Nomura, M.5
  • 52
    • 0029130168 scopus 로고
    • Identification of a signal for rapid export of proteins from the nucleus
    • Wen W, Meinkoth JL, Tsien RY, Taylor SS. Identification of a signal for rapid export of proteins from the nucleus. Cell 1995, 82, 463-473.
    • (1995) Cell , vol.82 , pp. 463-473
    • Wen, W.1    Meinkoth, J.L.2    Tsien, R.Y.3    Taylor, S.S.4
  • 53
    • 0029130169 scopus 로고
    • The HIV-1 Rev activation domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAs
    • Fischer U, Huber J, Boelens WC, Mattaj IW, Luhrmann R. The HIV-1 Rev activation domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAs. Cell 1995, 82, 475-483.
    • (1995) Cell , vol.82 , pp. 475-483
    • Fischer, U.1    Huber, J.2    Boelens, W.C.3    Mattaj, I.W.4    Luhrmann, R.5
  • 54
    • 0031079648 scopus 로고    scopus 로고
    • Leptomycin B is an inhibitor of nuclear export: Inhibition of nucleo-cytoplasmic translocation of the human immunodificiency virus type 1 (HIV-1) Rev protein and Rev-dependent mRNA
    • Wolff B, Sanglier, JJ, Wang Y. Leptomycin B is an inhibitor of nuclear export: inhibition of nucleo-cytoplasmic translocation of the human immunodificiency virus type 1 (HIV-1) Rev protein and Rev-dependent mRNA. Chem Biol 1997, 4, 139-147.
    • (1997) Chem Biol , vol.4 , pp. 139-147
    • Wolff, B.1    Sanglier, J.J.2    Wang, Y.3
  • 55
    • 0028318159 scopus 로고
    • Leptomycin B targets a regulatory cascade of CRM1, a fission yeast nuclear protein, involved in control of higher order chromosome structure and gene expression
    • Nishi K, Yoshida M, Fujiwara D, Nishikawa M, Horinouchi S, Beppu T. Leptomycin B targets a regulatory cascade of CRM1, a fission yeast nuclear protein, involved in control of higher order chromosome structure and gene expression. J Biol Chem 1994, 269, 6320-6324.
    • (1994) J Biol Chem , vol.269 , pp. 6320-6324
    • Nishi, K.1    Yoshida, M.2    Fujiwara, D.3    Nishikawa, M.4    Horinouchi, S.5    Beppu, T.6
  • 56
    • 0024654957 scopus 로고
    • Higher order chromosome structure is affected by cold-sensitive mutations in a Schizosaccharomyces pombe gene CRM1+, which encodes a 115-kD protein preferentially localized in the nucleus and its periphery
    • Adachi Y, Yanagida M. Higher order chromosome structure is affected by cold-sensitive mutations in a Schizosaccharomyces pombe gene CRM1+, which encodes a 115-kD protein preferentially localized in the nucleus and its periphery. J Cell Biol 1989, 108, 1195-1207.
    • (1989) J Cell Biol , vol.108 , pp. 1195-1207
    • Adachi, Y.1    Yanagida, M.2
  • 57
    • 0030924190 scopus 로고    scopus 로고
    • CRM1 is an export receptor for leucine-rich nuclear export signal
    • Fornerod M, Ohno M, Yoshida M, Mattaj IW. CRM1 is an export receptor for leucine-rich nuclear export signal. Cell 1997, 90, 1052-1060.
    • (1997) Cell , vol.90 , pp. 1052-1060
    • Fornerod, M.1    Ohno, M.2    Yoshida, M.3    Mattaj, I.W.4
  • 58
    • 0030831534 scopus 로고    scopus 로고
    • CRM1 is responsible for intracellular transport mediated by the nuclear export signal
    • Fukuda M, Asano S, Nakamura T, Adachi M, Yoshida M, Yanagida M, Nishida E. CRM1 is responsible for intracellular transport mediated by the nuclear export signal. Nature 1997, 390, 308-311.
    • (1997) Nature , vol.390 , pp. 308-311
    • Fukuda, M.1    Asano, S.2    Nakamura, T.3    Adachi, M.4    Yoshida, M.5    Yanagida, M.6    Nishida, E.7
  • 60
    • 0342276108 scopus 로고    scopus 로고
    • Export of importin α from the nucleus is mediated by a specific nuclear transport factor
    • Kutay U, Bischoff FR, Kostka S, Kraft R, Görlich D. Export of importin α from the nucleus is mediated by a specific nuclear transport factor. Cell 1997, 90, 1061-1071.
    • (1997) Cell , vol.90 , pp. 1061-1071
    • Kutay, U.1    Bischoff, F.R.2    Kostka, S.3    Kraft, R.4    Görlich, D.5
  • 61
    • 0029972194 scopus 로고    scopus 로고
    • The rapid inactivation of nuclear tyrosine phosphorylated Stat1 depends upon a protein tyrosine phosphatase
    • Haspel RL, Salditt-Georgieff M, Darnell JE, Jr. The rapid inactivation of nuclear tyrosine phosphorylated Stat1 depends upon a protein tyrosine phosphatase. EMBO J 1996, 15, 6262-6268.
    • (1996) EMBO J , vol.15 , pp. 6262-6268
    • Haspel, R.L.1    Salditt-Georgieff, M.2    Darnell J.E., Jr.3


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