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Volumn 62, Issue 24, 1997, Pages 8341-8349

Palladium-Catalyzed Stille Couplings with Fluorous Tin Reactants

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EID: 0344565329     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo9709413     Document Type: Article
Times cited : (105)

References (61)
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    • Interesting alternatives to the standard methyl and butyl reagents are available. For example, see: a) Vedejs, E.; Haight, A. R.; Moss, W. O. J. Am. Chem. Soc. 1992, 114, 6556. b) Brown, J. M.; Pearson, M.; Jastrzebski, J. T. B. H.; van Koten, G. J. Chem. Soc., Chem. Commun. 1992, 1440.
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    • For a new separation and recyling procedure and references to other procedures, see: Crich, D.; Sun, S. R. J. Org. Chem. 1996, 61, 7200.
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    • note
    • Most of the residual 10 - 20% remained in the organic phase. If desired, this can be removed by washing with FC-72, as shown in the Preparative procedure.
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    • See, Gronowitz, S.; Bjórk, P.; Malm, J.; Hórnfeldt, A.-B. J. Organomet. Chem. 1993, 460, 127. The yield problem can be solved by adding copper salts. This technique is likewise successful in the microwave variant of the fluorous Stille coupling (ref 12b).
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