Differential expression of bcl-w and bcl-x messenger RNA in the developing and adult rat nervous system

Neuroscience

Volumn 91, Issue 2, 1999, Pages 673-684

  Hamner S ^a   Skoglosa Y ^a   Lindholm, D ^a  

^a Devmtl Neurosci Box 587 BMC S ^*  (Sweden)

Author keywords

Bcl 2; Brain development; Cell death; Gene regulation; In situ hybridization; Neuronal culture

Indexed keywords

CELL PROTEIN; PROTEIN BCL 2; PROTEIN BCL W; PROTEIN BCL X; UNCLASSIFIED DRUG;

ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN CORTEX; GENE CONTROL; GRANULE CELL; HIPPOCAMPUS; IN SITU HYBRIDIZATION; MOLECULAR CLONING; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; NORTHERN BLOTTING; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPINAL CORD; SPINAL GANGLION; THALAMUS; TISSUE DISTRIBUTION;

AGING; ANIMALS; APOPTOSIS; BCL-X PROTEIN; BRAIN; CLONING, MOLECULAR; DNA, COMPLEMENTARY; EMBRYONIC AND FETAL DEVELOPMENT; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; IN SITU HYBRIDIZATION; NERVE TISSUE PROTEINS; ORGAN SPECIFICITY; PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, WISTAR; RNA, MESSENGER; SPINAL CORD; TRANSCRIPTION, GENETIC;

EID: 0344492705     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(98)00642-3     Document Type: Article

References (46)

1. Allsopp T.E., Wyatt S., Paterson H.F., Davies A.M. The proto-oncogene bcl-2 can selectively rescue neurotrophic factor-dependent neurons from apoptosis. Cell. 73:1993;295-307.
2. Alonso G., Guillemain I., Dumoulin A., Privat A., Patey G. Immunolocalization of Bcl-xL/S in the central nervous system of neonatal and adult rats. Cell Tiss. Res. 288:1997;59-68.
3. Barde Y.-A. Trophic factors and neuronal survival. Neuron. 2:1989;1525-1534.
4. Boise L.H., Gonzalez Garcia M., Postema C.E., Ding L., Lindsten T., Turka L.A., Mao X., Nunez G., Thompson C.B. bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death. Cell. 74:1993;597-608.
5. Brewer G., Cotman C. Survival and growth of hippocampal neurons in defined medium at low density: advantages of a sandwich culture technique or low oxygen. Brain Res. 494:1989;65-74.
6. Castren E., Ohga Y., Berzaghi M.P., Tzimagiorgis G., Thoenen H., Lindholm D. bcl-2 messenger RNA is localized in neurons of the developing and adult rat brain. Neuroscience. 61:1994;165-177.
7. Chang B.S., Minn A.J., Muchmore S.W., Fesik S.W., Thompson C.B. Identification of a novel regulatory domain in Bcl-X(L) and Bcl-2. Eur. molec. Biol. Org. J. 16:1997;968-977.
8. Cheng E., Kirsch D., Clem R., Ravi R., Kastan M., Bedi A., Ueno K., Hardwick M. Conversion of Bcl-2 to a Bax-like death effector by caspases. Science. 278:1997;1966-1968.
9. Chittenden T., Harrington E.A., O'Connor R., Flemington C., Lutz R.J., Evan G.I., Guild B.C. Induction of apoptosis by the Bcl-2 homologue Bak. Nature. 374:1995;733-736.
10. Chomczynski P., Sacchi N. Single-step method of RNA isolation by guanidinium thiocyanate-phenol-chloroform extraction. Analyt. Biochem. 162:1987;156-159.
11. Cleary M., Smith S., Sklar J. Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14;18) translocation. Cell. 47:1986;19-28.
12. Clem R., Cheng E., Karp C., Kirsch D., Ueno K., Takahashi A., Kastan M., Griffin D., Earnshaw W., Veliuona M., Hardwick M. Modulation of cell death by Bcl-xL through caspase interaction. Proc. natn. Acad. Sci. U.S.A. 95:1998;554-559.
13. Dubois-Dauphin M., Frankowski H., Tsujimoto Y., Huarte J., Martinou J.-C. Neonatal motoneurons overexpressing the bcl-2 protooncogene in transgenic mice are protected from axotomy-induced cell death. Proc. natn. Acad. Sci. U.S.A. 91:1994;3309-3313.
14. Farlie P.G., Dringen R., Rees S.M., Kannourakis G., Bernard O. bcl-2 transgene expression can protect neurons against developmental and induced cell death. Proc. natn. Acad. Sci. U.S.A. 92:1995;4397-4401.
15. Farrow S., White J., Martinou I., Raven T., Pun K., Grinham C., Martinou J., Brown R. Cloning of a bcl-2 homologue by interaction with adenovirus E1B 19K. Nature. 374:1995;731-733.
16. Ferrer I., Tortosa A., Condom E., Blanco R., Macaya A., Planas A. Increased expression of bcl-2 immunoreactivity in the developing cerebral cortex of the rat. Neurosci. Lett. 179:1994;13-16.
17. Frankowski H., Missotten M., Fernandez P.A., Martinou I., Michel P., Sadoul R., Martinou J.C. Function and expression of the Bcl-x gene in the developing and adult nervous system. NeuroReport. 6:1995;1917-1921.
18. Garcia I., Martinou I., Tsujimoto Y., Martinou J.-C. Prevention of programmed cell death of sympathetic neurons by the bcl-2 proto-oncogene. Science. 258:1992;302-304.
19. Gibson L., Holmgreen S.P., Huang D.C., Bernard O., Copeland N.G., Jenkins N.A., Sutherland G.R., Baker E., Adams J.M., Cory S. bcl-w, a novel member of the bcl-2 family, promotes cell survival. Oncogene. 13:1996;665-675.
20. Gonzalez-Garcia M., Garcia I., Ding L., O'Shea S., Boise L.H., Thompson C.B., Nunez G. bcl-x is expressed in embryonic and postnatal neural tissues and functions to prevent neuronal cell death. Proc. natn. Acad. Sci. U.S.A. 92:1995;4304-4308.
21. Gonzalez-Garcia M., Perez Ballestero R., Ding L., Duan L., Boise L.H., Thompson C.B., Nunez G. bcl-XL is the major bcl-x mRNA form expressed during murine development and its product localizes to mitochondria. Development. 120:1994;3033-3042.
22. Kamada S., Shmono A., Shinto Y., Tsujimura T., Takahashi T., Noda T., Kitamura Y., Kondoh H., Tsujimoto Y. Bcl-2 defiecency in mice leads to pleiotropic abnormalities: accelerated lymphoid cell death in thymus and spleen, polycystic kidney, hair hypopigmentation, and distorted small intestine. Cancer Res. 55:1995;354-359.
23. Kane D., Örd T., Anton R., Bredesen D. Expression of bcl-2 inhibits necrotic neural cell death. J. Neurosci. Res. 40:1995;269-275.
24. Kerr J., Wyllie A., Currie A. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br. J. Cancer. 26:1972;239-257.
25. Kiefer M.C., Brauer M.J., Powers V.C., Wu J.J., Umansky S.R., Tomei L.D., Barr P.J. Modulation of apoptosis by the widely distributed Bcl-2 homologue Bak. Nature. 374:1995;736-739.
26. Kozopas K., Yang T., Buchan H., Zhou P., Craig R. MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to Bcl2. Proc. natn. Acad. Sci. U.S.A. 90:1993;3516-3520.
27. Lindholm D., Dechant G., Heisenberg C.-P., Thoenen H. Brain-derived neurotrophic factor is a survival factor for cultured rat cerebellar granular neurons and protects them against glutamate-induced neurotoxicity. Eur. J. Neurosci. 5:1993;1455-1464.
28. Martinou J.-C., Dubois-Dauphin M., Staple J., Rodriguez I., Frankowski H., Missotten M., Albertini P., Talabot D., Catsicas S., Pietra C., Huarte J. Overexpression of Bcl-2 in transgenic mice protects neurons from naturally occuring cell death and experimental ischemia. Neuron. 13:1994;1017-1030.
29. Merry D.E., Veis D.J., Hickey W.F., Korsmeyer S.J. bcl-2 protein expression is widespread in the developing nervous system and retained in the adult PNS. Development. 120:1994;301-311.
30. Michaelidis T.M., Sendtner M., Cooper J.D., Airaksinen M.S., Holtmann B., Meyer M., Thoenen H. Inactivation of bcl-2 results in progressive degeneration of motoneurons, sympathetic and sensory neurons during early postnatal development. Neuron. 17:1996;75-89.
31. Minn A.J., Boise L.H., Thompson C.B. Bcl-x(S) antagonizes the protective effects of Bcl-x(L). J. biol. Chem. 271:1996;6306-6312.
32. Mizuguchi M., Sohma O., Takashima S., Ikeda K., Yamada M., Shiraiwa N., Ohta S. Immunochemical and immunohistochemical localization of Bcl-x protein in the rat central nervous system. Brain Res. 712:1996;281-286.
33. Motoyama N., Wang F., Roth K.A., Sawa H., Nakayama K., Nakayama K., Negishi I., Senju S., Zhang Q., Fujii S., Loh D.Y. Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice. Science. 267:1995;1506-1510.
34. Nakayama K., Nakayama K., Negishi I., Kuida K., Sawa H., Loh D.Y. Targeted disruption of Bcl-2 alpha beta in mice: occurrence of gray hair, polycystic kidney disease, and lymphocytopenia. Proc. natn. Acad. Sci. U.S.A. 91:1994;3700-3704.
35. Ohga Y., Zirrgiebel U., Hamnér S., Michaelidis T.M., Cooper J., Thoenen H., Lindholm D. Cell density increases Bcl-2 and Bcl-x expression in addition to survival of cultured cerebellar granule neurons. Neuroscience. 73:1996;913-917.
36. Oltvai Z.N., Milliman C.L., Korsmeyer S.J. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell. 74:1993;609-619.
37. Oppenheim R. Cell death during development of the nervous system. A. Rev. Neurosci. 14:1991;453-501.
38. Pinon L.G., Middleton G., Davies A.M. Bcl-2 is required for cranial sensory neuron survival at defined stages of embryonic development. Development. 124:1997;4173-4178.
39. Ross A., Waymire K., Moss J., Parlow A., Skinner M., Rusell L., MacGregor G. Testicular degeneration in Bclw-deficient mice. Nature Genet. 18:1998;251-256.
40. Sato T., Hanada M., Bodrug S., Irie S., Iwama N., Boise L., Thompson C., Golemis E., Fong L., Wang H.-G., Reed J. Interactions among members of the Bcl-2 protein family analyzed with a yeast two-hybrid system. Proc. natn. Acad. Sci. U.S.A. 91:1994;9238-9242.
41. Sedlak T., Oltvai Z., Yang E., Wang K., Boise L., Thompson C., Korsmeyer S. Multiple Bcl-2 family members demonstrate selective dimerizations with Bax. Proc. natn. Acad. Sci. U.S.A. 92:1995;7834-7838.
42. Tsujimoto Y., Finger L., Yunis J., Nowell P., Croce C. Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation. Science. 226:1984;1097-1099.
43. Tsujimoto Y., Shimizu S., Eguchi Y., Kamiike W., Matsuda H. Bcl-2 and Bcl-xL block apoptosis as well as necrosis: possible involvement of common mediators in apoptotic and necrotic signal transduction pathways. Leukemia. 11:1997;380-382.
44. Veis D., Sorenson C., Shutter J., Korsmeyer S. Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair. Cell. 75:1993;229-240.
45. Vekrellis K., McCarthy M.J., Watson A., Whitfield J., Rubin L.L., Ham J. Bax promotes neuronal cell death and is downregulated during the development of the nervous system. Development. 124:1997;1239-1249.
46. Zhong L.-T., Sarafian T., Kane D., Charles A., Mah S., Edwards R., Bredesen D. bcl-2 inhibits death of central neural cells induced by multiple agents. Proc. natn. Acad. Sci. U.S.A. 90:1993;4533-4537.