Persistent reversal of P-glycoprotein-mediated daunorubicin resistance by tetrandrine in multidrug-resistant human T lymphoblastoid leukemia MOLT-4 cells

Journal of Pharmacy and Pharmacology

Volumn 55, Issue 11, 2003, Pages 1531-1537

  Liu, Zhen Li ^a,b   Hirano, Toshihiko ^a   Tanaka, Sachiko ^a   Onda, Kenji ^a   Oka, Kitaro ^a  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

^b INSTITUTE OF CHINESE MATERIA MEDICA   (China)

Author keywords

[No Author keywords available]

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ANTINEOPLASTIC AGENT; CYCLOSPORIN; DAUNORUBICIN; DOXORUBICIN; GLYCOPROTEIN P; MONOCLONAL ANTIBODY; PHYCOERYTHRIN CONJUGATED GYLCOPROTEIN P MONOCLONAL ANTIBODY 17F9; RHODAMINE 123; TETRANDRINE; UNCLASSIFIED DRUG; VINBLASTINE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG CYTOTOXICITY; DRUG INHIBITION; DRUG POTENTIATION; DRUG STRUCTURE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; INHIBITION KINETICS; LYMPHATIC LEUKEMIA; LYMPHOCYTE TRANSFORMATION; MULTIDRUG RESISTANCE; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; STAINING; T LYMPHOBLAST;

ALKALOIDS; ANTIBIOTICS, ANTINEOPLASTIC; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BENZYLISOQUINOLINES; DAUNORUBICIN; DRUG RESISTANCE, MULTIPLE; FLOW CYTOMETRY; HUMANS; LEUKEMIA, T-CELL; P-GLYCOPROTEIN; TUMOR CELLS, CULTURED;

EID: 0344444784     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/0022357022115     Document Type: Article

References (21)

1. Aihara, M., Aihara, Y., Schmidt-Wolf, G., Schmidt-Wolf, I., Sikic, B. I., Blume, K. G., Chao, N. J. (1991) A combined approach for purging multidrug-resistant leukemic cell lines in bone marrow using a monoclonal antibody and chemotherapy. Blood 77: 2079-2084
2. Archinal-Mattheis, A., Rzepka, R.W., Watanabe, T., Kokubu, N., Itoh, Y., Combates, N.J., Bair, K. W., Cohen, D. (1995) Analysis of the interactions of SDZ PSC 833 ([3′-keto-Bmt1]-Val 2)-Cyclosporine), a multidrug resistance modulator, with P-glycoprotein. Oncol. Res. 7: 603-610
3. Boesch, D., Loor, F. (1994) Extent and persistence of P-glycoprotein inhibition in multidrug-resistant P388 cells after exposure to resistance-modifying agents. Anticancer Drugs 5: 229-238
4. Boesch, D., Muller, K., Pourtier-Manzanedo, A., Loor, F. (1991) Restoration of daunomycin retention in multidrug-resistant P388 cells by submicromolar concentrations of SDZ PSC 833, a nonimmunosuppressive cyclosporin derivative. Exp. Cell Res. 196: 26-32
5. Chaudhary, P. M., Roninson, I. B. (1991) Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells. Cell 66: 85-84
6. Choi, S. U., Park, S. H., Kim, K. H., Choi, E. J., Kim, S., Park, W. K., Zhang, Y. H., Kim, H. S., Jung, N. P., Lee, C. O. (1998) The bisbenzylisoquinoline alkaloids, tetrandrine and fangchinoline, enhance the cytotoxicity of multidrug resistance-related drugs via modulation of P-glycoprotein. Anticancer Drugs 9: 255-261
7. Dantzig, A. H., Shepard, R. L., Cao, J., Law, K. L., Ehlhardt, W. J., Baughman, T. M., Bumol, T. F., Startling, J. J. (1996) Reversal of P-glycoprotein-mediated multidrug resistance by a potent cyclopropyldibenzosuberane modulator, LY335979. Cancer Res. 56: 4171-4179
8. Di Pietro, A., Conseil, G., Perez-Victoria, J. M., Dayan, G., Baubichon-Cortay, H., Trompier, D., Steinfels, E., Jault, J.-M., De Wet, H., Maitrejean, M., Comte, G., Boumendjel, A., Mariotte, A.-M., Dumontet, C., MacIntosh, D. B., Goffeau, A., Castanys, S., Gamarro, F., Barron, D. (2002) Modulation by flavonoids of cell multidrug resistance mediated by P-glycoprotein and related ABC transporters. Cell. Mol. Life Sci. 59: 307-322
9. Foxwell, B. M., Mackie, A., Ling, V., Ryffel, B. (1989) Identification of the multidrug resistance-related P-glycoprotein as a cyclosporine binding protein. Mol. Pharmacol. 36: 543-546
10. Fukuda, T., Kamishima, T., Kakihara, T., Ohnishi, Y., Suzuki, T. (1996) Characterization of newly established human myeloid leukemia cell line (KF-19) and its drug resistant sublines. Leukemia Res. 20: 931-939
11. Germann, U. A., Shlyakhter, D., Mason, V. S., Zell, R. E., Duffy, J. P., Galullo, V., Armistead, D. M., Saunders, J. O., Boger, J., Harding, M. W. (1997) Cellular and biochemical characterization of VX-710 as a chemosensitizer: Reversal of P-glycoprotein-mediated multidrug resistance in vitro. Anticancer Drugs 8: 125-140
12. Hirano, T., Gotoh, M., Oka, K. (1994) Natural flavonoids and lignans as candidates for non-cytotoxic antiproliferative anti-leukemia. Life Sci. 55: 1061-1069
13. Hirano, T., Abe, K., Gotoh, M., Oka, K. (1995) Citrus flavone tangeretin inhibits leukaemic HL-60 cell growth partially through induction of apoptosis with less cytotoxicity on normal lymphocytes. Br. J. Cancer 72: 1380-1388
14. Hirano, T., Oka, K., Mimaki, Y., Kuroda, M., Sashida, Y. (1996) Potent growth inhibitory activity of a novel Ornithogalum chorestane glycoside on human cells: Induction of apoptosis in promyelocytic leukemia HL-60 cells. Life Sci. 58: 789-798
15. Hirano, T., Akashi, T., Keira, T., Oka, K., Ihoya, N., Yoshida, M. (2000) Clinical impact of cyclosporine cellular-pharmacodynamics in minimal change nephrotic syndrome. Clin. Pharmacol. Ther. 68: 532-540
16. Liu, Z-L., Onda, K., Tanaka, S., Toma, T., Hirano, T., Oka, K. (2002) Induction of multidrug resistance in MOLT-4 cells by anticancer agents is closely related to increased expression of functional P-glycoprotein and MDR1 mRNA. Cancer Chemother. Pharmacol. 49: 391-397
17. Ludescher, C., Thaler, J., Drach, D., Drach, J., Spitaler, M., Gattinger, C., Huber, H., Hofmann, J. (1992) Detection of activity of P-glycoprotein in human tumour samples using rhodamine 123. Br. J. Haematol. 82: 161-168
18. Naito, M., Oh-Hara, T., Yamazaki, A., Danki, T., Tsuruo, T. (1992) Reversal of multidrug resistance by an immunosuppressive agent FK-506. Cancer Chemother. Pharmacol. 29: 195-200
19. Newman, M. J., Rodarte, J. C., Benbatoul, K. D., Romano, S. J., Zhang, C., Moran, E. J., Uyeda, R. T., Dixon, R., Guns, E. S., Mayer, L. D. (2000) Discovery and characterization of OC144-093, a novel inhibitor of P-glycoprotein-mediated multidrug resistance. Cancer Res. 60: 2964-2972
20. Saeki, T., Ueda, K., Tanigawara, Y., Hori, R., Komano, T. (1993) Human P-glycoprotein transports cyclosporin A and FK506. J. Biol. Chem. 268: 6077-6080
21. Sikic, B. I. (1997) Pharmacologic approaches to reversing multidrug resistance. Semin. Hematol. 34: 40-47