Functional analysis of the human Sprouty2 gene promoter

Gene

Volumn 322, Issue 1-2, 2003, Pages 175-185

  Ding, Wei ^a   Bellusci, Saverio ^a   Shi, Wei ^a   Warburton, David ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Cis acting element; Lung development; Reporter gene assay; TATA less promoter; Transcription factor binding site; Transcription initiation site

Indexed keywords

COMPLEMENTARY DNA; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; NUCLEAR PROTEIN; TRANSCRIPTION FACTOR AP 2; TRANSCRIPTION FACTOR ETS 1; TRANSCRIPTION FACTOR SP1;

ARTICLE; CONTROLLED STUDY; DNA FLANKING REGION; FEMALE; FETUS; GEL MOBILITY SHIFT ASSAY; GENE; GENE AMPLIFICATION; GENE FUNCTION; GENE MAPPING; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC TRANSCRIPTION; GENOME; HUMAN; HUMAN CELL; MOLECULAR CLONING; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; SEQUENCE ANALYSIS; SPROUTY2 GENE; TATA BOX; TRANSCRIPTION INITIATION SITE;

MAMMALIA; MURINAE;

EID: 0344440845     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gene.2003.09.004     Document Type: Article

References (36)

1. Azizkhan J.C., Jensen D.E., Pierce A.J., Wade M. Transcription from TATA-less promoters: dihydrofolate reductase as a model. Crit. Rev. Eucaryot. Gene. Expr. 3:1993;229-254.
2. Bellusci S., Grindley J., Emoto H., Itoh N., Hogan B.L. Fibroblast growth factor 10 (FGF10) and branching morphogenesis in the embryonic mouse lung. Development. 124:1997;4867-4878.
3. Black A.R., Black J.D., Azizkhan J.C. Sp1 and krüppel-like factor family of transcription factors in cell growth regulation and cancer. J. Cell. Physiol. 188:2001;143-160.
4. Casci T., Vinos J., Freeman M. Sprouty, an intracellular inhibitor of Ras signaling. Cell. 96:1999;655-665.
5. Chambers D., Mason I. Expression of sprouty2 during early development of chick embryo is coincident with known sites of FGF signaling. Mech. Dev. 91:2000;361-364.
6. de Maximy A.A., Nakatake Y., Moncada S., Itoh N., Thiery J.P., Bellusci S. Cloning and expression pattern of a mouse homologue of Drosophila sprouty in the mouse embryo. Mech. Dev. 81:1999;213-216.
7. Goldhamer D.J., Faerman A., Shani M., Emerson C.P. Regulatory elements that control the lineage-specific expression of myoD. Science. 256:1992;538-542.
8. Gross I., Bassit B., Benezra M., Licht J.D. Mammalian sprouty proteins inhibit cell growth and differentiation by preventing ras activation. J. Biol. Chem. 276:2001;46460-46468.
9. Hacohen N., Kramer S., Sutherland D., Hiromi Y., Krasnow M.A. Sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways. Cell. 92:1998;253-263.
10. Hilger-Eversheim K., Moser M., Schorle H., Buettner R. Regulatory roles of AP-2 transcription factors in vertebrate development, apoptosis and cell-cycle control. Gene. 260:2000;1-12.
11. Impagnatiello M.A., Weitzer S., Gannon G., Compagni A., Cotten M., Christofori G. Mammalian sprouty-1 and -2 are membrane-anchored phosphoprotein inhibitors of growth factor signaling in endothelial cells. J. Cell Biol. 152:2001;1087-1098.
12. Javahery R., Khachi A., Lo K., Zenzie-Gregory B., Smale S.T. DNA sequence requirements for transcriptional initiator activity in mammalian cells. Mol. Cell. Biol. 14:1994;116-127.
13. Kaczynski J., Cook T., Urrutia R. Sp1- and Krüppel-like transcription factors. Genome Biol. 4:2003;206.1-206.8.
14. Kramer S., Okabe M., Hacohen N., Krasnow M.A., Hiromi Y. Sprouty: a common antagonist of FGF and EGF signaling pathways in Drosophila. Development. 126:1999;2515-2525.
15. Leask A., Byrne C., Fuchs E. Transcription factor AP2 and its role in epidermal-specific gene expression. Proc. Natl. Acad. Sci. U. S. A. 88:1991;7948-7952.
16. Li L., Miano M.M., Mercer B., Olson E.N. Expression of the SM22alpha promoter in transgenic mice provides evidence for distinct transcriptional regulatory programs in vascular and visceral smooth muscle cells. J. Cell Biol. 132:1996;849-859.
17. Mailleux A.A., Tefft D., Ndiaye D., Itoh N., Thiery J.P., Warburton D., Bellusci S. Evidence that Sprouty2 functions as an inhibitor of mouse embryonic lung growth and morphogenesis. Mech. Dev. 102:2001;81-94.
18. Maroulakou I.G., Bowe D.B. Expression and function of Ets transcription factors in mammalian development: a regulatory network. Oncogene. 19:2000;6432-6442.
19. Minowada G., Jarvis L.A., Chi C.L., Neubuser A., Sun X., Hacohen N., Krasnow M.A., Martin G.R. Vertebrate Sprouty genes are induced by FGF signaling and can cause chondrodysplasia when overexpressed. Development. 126:1999;4465-4475.
20. Mitchell P.J., Wang C., Tjian R. Positive and negative regulation of transcription in vitro: enhancer-binding protein AP-2 is inhibited by SV40 T antigen. Cell. 50:1987;847-861.
21. Nottoli T., Hagopian-Donaldson S., Zhang J., Perkins A., Williams T. AP-2-null cells disrupt morphogenesis of the eye, face, and limbs in chimeric mice. Proc. Natl. Acad. Sci. U. S. A. 95:1998;13714-13719.
22. Reich A., Sapir A., Shilo B.-Z. Sprouty is a general inhibitor of receptor tyrosine kinase signaling. Development. 126:1999;4139-4147.
23. Sasaki A., Taketomi T., Wakioka T., Kato R., Yoshimura A. Identification of a dominant negative mutant of Sprouty that potentiates fibroblast growth factor - but not epidermal growth factor-induced ERK activation. J. Biol. Chem. 276:2001;36804-36808.
24. Schorle H., Meier P., Buchert M., Jaenisch R., Mitchell P.J. Transcription factor AP-2 essential for cranial closure and craniofacial development. Nature. 381:1996;235-238.
25. Sekine K., Ohuchi H., Fujiwara M., Yamasaki M., Yoshizawa T., Sato T., Yagishita N., Matsui D., Koga Y., Itoh N., Kato S. Fgf-10 is essential for limb and lung formation. Nat. Genet. 21:1999;138-141.
26. Sementchenko V.I., Watson D.K. Ets target genes: past, present and future. Oncogene. 19:2000;6533-6548.
27. Shapiro M.B., Senapathy P. RNA splice junctions of different classes of eukaryotes: sequence statistics and functional implications in gene expression. Nucleic Acids Res. 15:1987;7155-7174.
28. Sharrocks A.D., Brown A.L., Ling Y., Yates P.R. The ETS-domain transcription factor family. Int. J. Cell Biol. 29:1997;1371-1387.
29. Smale S.T., Baltimore D. The "initiator" as a transcription control element. Cell. 57:1989;103-113.
30. Suske G. The Sp-family of transcription factors. Gene. 238:1999;291-300.
31. Sutherland D.C., Samakovlis C., Krasnow M.A. Branchless encodes a Drosophila FGF homolog that controls tracheal cell migration and the pattern of branching. Cell. 87:1996;1091-1101.
32. Tefft D., Lee M., Smith S., Leinwand M., Zhao J., Bringas P., Crowe D.L., Warburton D. Conserved function of mSpry-2, a murine homolog of Drosophila sprouty, which negatively modulates respiratory organogenesis. Curr. Biol. 9:1999;219-222.
33. Warburton D., Schwartz M., Tefft D., Flores-Delgado G., Anderson K.D., Cardoso W.V. The molecular basis of lung morphogenesis. Mech. Dev. 92:2000;55-81.
34. Werner T. Models for prediction and recognition of eukaryotic promoters. Mamm. Genome. 10:1999;168-175.
35. Wong E.S.M., Fong C.W., Lim J., Yusoff P., Low B.C., Langdon W.Y., Guy G.R. Sprouty2 attenuates epidermal growth factor receptor ubiquitylation and endocytosis, and consequently enhances Ras/ERK signaling. EMBO J. 21:2002;4796-4808.
36. Yigzaw Y., Cartin L., Pierre S., Scholich K., Patel T.B. The C terminus of Sprouty is important for modulation of cellular migration and proliferation. J. Biol. Chem. 276:2001;22742-22747.