Nitric oxide inhibits lung sodium transport through a cGMP-mediated inhibition of epithelial cation channels

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 274, Issue 4 18-4, 1998, Pages

  Jain, Lucky ^a   Chen, Xi Juan ^a   Brown, Lou Ann ^a   Eaton, Douglas C ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alveolar type II cells; Amiloride; Guanosine 3',5' cyclic monophosphate; Nonselective cation channel; S nitrosoglutathione; Single channel recording; Sodium channel

Indexed keywords

CYCLIC GMP; NITRIC OXIDE; SODIUM; SODIUM CHANNEL;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; LUNG ALVEOLUS CELL TYPE 2; LUNG ALVEOLUS EPITHELIUM; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT; SODIUM TRANSPORT;

EID: 0031979719     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.1998.274.4.l475     Document Type: Article

References (32)

1. Bland, R. D., and C. A. Boyd. Cation transport in lung epithelial cells derived from fetal, newborn, and adult rabbits. J. Appl. Physiol. 61: 507-515, 1986.
2. Brown, L. A. S., C. Bai, and D. P. Jones. Glutathione protection in alveolar type II cells from fetal and neonatal rabbits. Am. J. Physiol. 262 (Lung Cell. Mol. Physiol. 6): L305-L312, 1992.
3. + channel is made of three homologous subunits. Nature 367: 463-467, 1994.
4. + transport by an L-Arg-dependent mechanism. Am. J. Physiol. 266 (Cell Physiol. 35): C1330-C1341, 1994.
5. + channels. Biomed. Res. (Tokyo) 12: 31-35, 1991.
6. Eaton, D. C., A. Becchetti, H. Ma, and B. N. Ling. Renal sodium channels: regulation and single channel properties. Kidney Int. 48: 941-949, 1995.
7. Feng, Z., R. B. Clark, and Y. Berthiaume. Identification of nonselective cation channels in cultured adult rat alveolar type II cells. Am. J. Respir. Cell Mol. Biol. 9: 248-254, 1993.
8. Guidot, D. M., M. J. Repine, B. M. Hybertson, and J. E Repine. Inhaled nitric oxide prevents neutrophil-mediated, oxygen radical-dependent leak in isolated rat lungs. Am. J. Physiol 269 (Lung Cell. Mol. Physiol. 13): L2-L5, 1995.
9. Hummler, E., P. Barker, J. Gatzy, F. Beerman, C. Verdumo. A Schmidt, R. Boucher, and B. C. Rossier. Early death due to defective neonatal lung liquid clearance in α-ENaC-deficient mice. Nat. Genet. 12: 325-328, 1996.
10. Ichimori, K., H. Ishida, M. Fukahori, H. Nakazawa, and E. Burahami. Practical nitric oxide measurement employing a nitric oxide-selective electrode. Rev. Sci. Instrum. 65: 1-5, 1994.
11. + channel. J. Biol. Chem. 271: 807-816, 1996.
12. Kase, H. New inhibitors of protein kinases from microbial sources. In: Biology of Actinomycetes 88: Proceedings of Seventh International Symposium on Biology of Actinomycetes, edited by Y. Okami, T. Bappu, and H. Ogawara. Tokyo: Japan Scientific Societies Press, 1988, p. 159-164.
13. Kizer, N., X.-L. Guo, and K. Kruska. Reconstitution of stretch activated cation channels by expression of the alpha subunit of the epithelial sodium channel cloned from osteoblasts. Proc. Natl. Acad. Sci. USA 94: 1013-1018, 1997.
14. Koivisto, A., and J. Nedergaard. Modulation of calcium activated non-selective cation channel by nitric oxide in rat brown adipose tissue. J. Physiol. (Lond.) 486: 59-65, 1995.
15. + channels in a distal nephron line (A6). Am. J. Physiol. 267 (Cell Physiol. 36): C1414-C1425, 1994.
16. Light, D. B., J. D. Corbin, and B. A Stanton. Dual ion channel regulation by cyclic GMP and cyclic GMP-dependent protein kinase. Nature 344: 336-339, 1990.
17. +-permeant channels in the fetal distal lung epithelium. Pflügers Arch. 431: 748-756, 1996.
18. Marunaka, Y., and D. C. Eaton. Chloride channels in the apical membrane of a distal nephron A6 cell line. Am. J. Physiol. 258 (Cell Physiol. 27): C352-C368, 1990.
19. Matalon, S. Mechanisms and regulation of ion transport in adult mammalian alveolar type II pneumocytes. Am. J. Physiol. 261 (Cell Physiol. 30): C727-C738, 1991.
20. Matthay, M. A., H. G. Folkesson, and A S. Verkman. Salt and water transport across alveolar and distal airway epithelia in the adult lung. Am. J. Physiol. 270 (Lung Cell. Mol. Physiol. 14): L487-L503, 1996.
21. Moncada, S., R. M. J. Palmer, and E. A Higgs. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol. Rev. 43: 109-142, 1991.
22. O'Brodovich, H., V. Hannam, M. Seear, and J. B. M. Mullen. Amiloride impairs lung water clearance in newborn guinea pigs. J. Appl. Physiol. 68: 1758-1762, 1990.
23. O'Brodovich, H., B. Rafii, and P. Perlon. Arginine vasopressin and atrial natriuretic peptide do not alter ion transport by cultured fetal distal lung epithelium. Pediatr. Res. 31: 318-322, 1992.
24. Orser, B. A., L. Bertlik, L. Fedorko, and H. O'Brodovich. Cation selective channel in fetal alveolar type II epithelium. Biochim. Biophys. Acta 1094: 19-26, 1991.
25. Pepke-Zaba, J., T. W. Higgenbottam, A. T. Dinh-Zuan, D. Stone, and J. Wallwork. Inhaled nitric oxide causes selective pulmonary vasodilatation in patients with pulmonary hypertension. Lancet 338: 1173-1174, 1991.
26. Rocha, A. S., and L. H. Kudo. Atrial peptide and cGMP effects on NaCl transport in inner medullary collecting duct. Am. J. Physiol. 259 (Renal Fluid Electrolyte Physiol. 28): F258-F268, 1990.
27. Rossiant, R., K. S. Falke, F. Lopez, K. Slama, U. Pison, and W. M. Zapol. Inhaled nitric oxide for the adult respiratory distress syndrome. N. Engl. J. Med. 328: 399-405, 1993.
28. Scherrer, U., L. Vollenweider, A. Delabays, M. Savcic, U. Eichenberger, G. R. Kleger, A. Fikrle, P. E. Ballmer, P. Nicod, and P. Bartsch. Inhaled nitric oxide for high altitude pulmonary edema. N. Engl. J. Med. 334: 624-629, 1996.
29. + reabsorption in the isolated perfused cortical collecting duct. J. Am. Soc. Nephrol. 6: 89-94, 1995.
30. 2+-activated nonselective cation channel in β-agonist-treated fetal lung epithelium. Am. J. Physiol. 266 (Cell Physiol. 35): C104-C109, 1994.
31. + channel: biophysical properties, pharmacology, autogenesis, and molecular cloning. Proc. Natl. Acad. Sci. USA 91: 247-251, 1994.
32. Wahler, G. M., and S. J. Dollinger. Nitric oxide donor SIN-1 inhibits mammalian cardiac calcium current through cGMP-dependent protein kinase. Am. J. Physiol. 268 (Cell Physiol. 37): C45-C54, 1995.