Diacylglycerol pyrophosphate phosphatase in Saccharomyces cerevisiae

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1635, Issue 1, 2003, Pages 1-9

  Oshiro, June ^a   Han, Gil Soo ^a   Carman, George M ^a,b  

^a RUTGERS UNIVERSITY   (United States)

^b RUTGERS UNIVERSITY   (United States)

Author keywords

Diacylglycerol pyrophosphate phosphatase; Growth phase; Inositol; Phosphatidate; Yeast; Zinc

Indexed keywords

DIACYLGLYCEROL; DIACYLGLYCEROL PYROPHOSPHATE; DIACYLGLYCEROL PYROPHOSPHATE PHOSPHATASE; FUNGAL ENZYME; INOSITOL; LIPID; MAGNESIUM ION; MEMBRANE ENZYME; N ETHYLMALEIMIDE; PHOSPHATASE; PHOSPHATE; PHOSPHATIDIC ACID; PYROPHOSPHORIC ACID DERIVATIVE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GIS1P; TRANSCRIPTION FACTOR ZAP1P; UNCLASSIFIED DRUG; ZINC;

CATALYSIS; CELL LEVEL; CORRELATION ANALYSIS; DEPHOSPHORYLATION; DEPLETION; DNA RESPONSIVE ELEMENT; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME PURIFICATION; ENZYME REGULATION; ENZYME STRUCTURE; FUNGAL GENE; GENE CONTROL; GENE EXPRESSION; GENE INDUCTION; GENE REPRESSION; GENETIC CODE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN LOCALIZATION; PROTEIN MOTIF; REGULATORY MECHANISM; REVIEW; SACCHAROMYCES CEREVISIAE; SUPPLEMENTATION; TONOPLAST; TOPOGRAPHY; YEAST;

SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 0344395243     PISSN: 13881981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbalip.2003.10.002     Document Type: Review

References (76)

1. Wu W.-I., Liu Y., Riedel B., Wissing J.B., Fischl A.S., Carman G.M. Purification and characterization of diacylglycerol pyrophosphate phosphatase from Saccharomyces cerevisiae. J. Biol. Chem. 271:1996;1868-1876.
2. Brindley D.N., Waggoner D.W. Mammalian lipid phosphate phosphohydrolases. J. Biol. Chem. 273:1998;24281-24284.
3. Brindley D.N., English D., Pilquil C., Buri K., Ling Z.C. Lipid phosphate phosphatases regulate signal transduction through glycerolipids and sphingolipids. Biochim. Biophys. Acta. 1582:2002;33-44.
4. Stukey J., Carman G.M. Identification of a novel phosphatase sequence motif. Protein Sci. 6:1997;469-472.
5. Toke D.A., McClintick M.L., Carman G.M. Mutagenesis of the phosphatase sequence motif in diacylglycerol pyrophosphate phosphatase from Saccharomyces cerevisiae. Biochemistry. 38:1999;14606-14613.
6. Riedel B., Morr M., Wu W.-I., Carman G.M., Wissing J.B. Metabolism of diacylglycerol pyrophosphate by suspension cultured Catharanthus roseus cells. Identification and characterization of diacylglycerol pyrophosphatase phosphatase in plants. Plant Sci. 128:1997;1-10.
7. Wissing J.B., Behrbohm H. Diacylglycerol pyrophosphate, a novel phospholipid compound. FEBS Lett. 315:1993;95-99.
8. Heim S., Bauleke A., Wylegalla C., Wagner K.G. Evidence of phosphatidylinositol and diacylglycerol kinases in suspension cultured plant cells. Plant Sci. 49:1987;159-165.
9. Sommarin M., Sandelius A.S. Phosphatidylinositol and phosphatidylinositolphosphate kinases in plant membranes. Biochim. Biophys. Acta. 958:1988;268-278.
10. +-ATPase in plasma membrane of sunflower hypocotyls. J. Biol. Chem. 265:1990;14817-14821.
11. Oshiro J., Rangaswamy S., Chen X., Han G.-S., Quinn J.E., Carman G.M. Regulation of the DPP1-encoded diacylglycerol pyrophosphate (DGPP) phosphatase by inositol and growth phase. Inhibition of DGPP phosphatase activity by CDP-diacylglycerol and activation of phosphatidylserine synthase activity by DGPP. J. Biol. Chem. 275:2000;40887-40896.
12. Michell R.H. Inositol lipids in cellular signalling mechanisms. Trends Biochem. Sci. 17:1992;274-276.
13. Berridge M.J. Inositol lipids and cell proliferation. Biochim. Biophys. Acta. 907:1987;33-45.
14. Majerus P.W., Ross T.S., Cunningham T.W., Caldwell K.K., Jefferson A.B., Bansal V.S. Recent insights in phosphatidylinositol signaling. Cell. 63:1990;459-465.
15. Downes C.P., Macphee C.H. myo-Inositol metabolites as cellular signals. Eur. J. Biochem. 193:1990;1-18.
16. Divecha N., Irvine R.F. Phospholipid signaling. Cell. 80:1995;269-278.
17. Munnik T., de Vrije T., Irvine R.F., Musgrave A. Identification of diacylglycerol pyrophosphate as a novel metabolic product of phosphatidic acid during G-protein activation in plants. J. Biol. Chem. 271:1996;15708-15715.
18. Munnik T., Meijer H.J.G., Ter Riet B., Hirt H., Frank W., Bartels D., Musgrave A. Hyperosmotic stress stimulates phospholipase D activity and elevates the levels of phosphatidic acid and diacylglycerol pyrophosphate. Plant J. 22:2000;147-154.
19. Den Hartog M., Musgrave A., Munnik T. Nod factor-induced phosphatidic acid and diacylglycerol pyrophosphate formation: a role for phospholipase C and D in root hair deformation. Plant J. 25:2001;55-65.
20. Van der Luit A.H., Piatti T., Van Doorn A., Musgrave A., Felix G., Boller T., Munnik T. Elicitation of suspension-cultured tomato cells triggers the formation of phosphatidic acid and diacylglycerol pyrophosphate. Plant Physiol. 123:2000;1507-1515.
21. Moolenaar W.H., Kruijer W., Tilly B.C., Verlaan I., Bierman A.J., de Laat S.W. Growth factor-like action of phosphatidic acid. Nature. 323:1986;171-173.
22. Yu C.-L., Tsai M.-H., Stacey D.W. Cellular ras activity and phospholipid metabolism. Cell. 52:1988;63-71.
23. Gomez-Munoz A., Martin A., O'Brien L., Brindley D.N. Cell-permeable ceramides inhibit the stimulation of DNA synthesis and phospholipase D activity by phosphatidate and lysophosphatidate in rat fibroblasts. J. Biol. Chem. 269:1994;8937-8943.
24. Balboa M., Balsinde J., Dillon D.A., Carman G.M., Dennis E.A. Proinflammatory macrophage-activating properties of the novel phospholipid diacylglycerol pyrophosphate. J. Biol. Chem. 274:1999;522-526.
25. Carman G.M., Zeimetz G.M. Regulation of phospholipid biosynthesis in the yeast Saccharomyces cerevisiae. J. Biol. Chem. 271:1996;13293-13296.
26. Toke D.A., Bennett W.L., Dillon D.A., Chen X., Oshiro J., Ostrander D.B., Wu W.-I., Cremesti A., Voelker D.R., Fischl A.S., Carman G.M. Isolation and characterization of the Saccharomyces cerevisiae DPP1 gene encoding for diacylglycerol pyrophosphate phosphatase. J. Biol. Chem. 273:1998;3278-3284.
27. 2+-independent phosphatidate phosphatase. J. Biol. Chem. 273:1999;14331-14338.
28. Han G.-S., Johnston C.N., Chen X., Athenstaedt K., Daum G., Carman G.M. Regulation of the Saccharomyces cerevisiae DPP1-encoded diacylglycerol pyrophosphate phosphatase by zinc. J. Biol. Chem. 276:2001;10126-10133.
29. Dillon D.A., Wu W.-I., Riedel B., Wissing J.B., Dowhan W., Carman G.M. The Escherichia coli pgpB gene encodes for a diacylglycerol pyrophosphate phosphatase activity. J. Biol. Chem. 271:1996;30548-30553.
30. 2+-independent phosphatidate phosphatase (PAP2) displays diacylglycerol pyrophosphate phosphatase activity. J. Biol. Chem. 272:1997;10361-10366.
31. Faulkner A.J., Chen X., Rush J., Horazdovsky B., Waechter C.J., Carman G.M., Sternweis P.C. The LPP1 and DPP1 gene products account for most of the isoprenoid phosphatase activities in Saccharomyces cerevisiae. J. Biol. Chem. 274:1999;14831-14837.
32. Carman G.M. Phosphatidate phosphatases and diacylglycerol pyrophosphate phosphatases in Saccharomyces cerevisiae and Escherichia coli. Biochim. Biophys. Acta. 1348:1997;45-55.
33. Hemrika W., Renirie R., Dekker H.L., Barnett P., Wever R. From phosphatases to vanadium peroxidases: a similar architecture of the active site. Proc. Natl. Acad. Sci. U. S. A. 94:1997;2145-2149.
34. Neuwald A.F. An unexpected structural relationship between integral membrane phosphatases and soluble haloperoxidases. Protein Sci. 6:1997;1764-1767.
35. 2-inducible hic53 clone yielded the cDNA encoding phosphatidic acid phosphatase. J. Biol. Chem. 271:1996;18931-18938.
36. Furneisen J.M., Carman G.M. Enzymological properties of the LPP1-encoded lipid phosphatase from Saccharomyces cerevisiae. Biochim. Biophys. Acta. 1484:2000;71-82.
37. Qie L., Nagiec M.M., Baltisberger J.A., Lester R.L., Dickson R.C. Identification of a Saccharomyces gene, LCB3, necessary for incorporation of exogenous long chain bases into sphingolipids. J. Biol. Chem. 272:1997 (6-27);16110-16117.
38. Mandala S.M., Thornton R., Tu Z.X., Kurtz M.B., Nickels J., Broach J., Menzeleev R., Spiegel S. Sphingoid base 1-phosphate phosphatase: a key regulator of sphingolipid metabolism and stress response. Proc. Natl. Acad. Sci. U. S. A. 95:1998;150-155.
39. Mao C.G., Wadleigh M., Jenkins G.M., Hannun Y.A., Obeid L.M. Identification and characterization of Saccharomyces cerevisiae dihydrosphingosine-1-phosphate phosphatase. J. Biol. Chem. 272:1997;28690-28694.
40. Fernandez F., Rush J.S., Toke D.A., Han G.S., Quinn J.E., Carman G.M., Choi J.Y., Voelker D.R., Aebi M., Waechter C.J. The CWH8 gene encodes a dolichyl pyrophosphate phosphatase with a luminally oriented active site in the endoplasmic reticulum of Saccharomyces cerevisiae. J. Biol. Chem. 276:2001;41455-41464.
41. Greenberg M., Reiner B., Henry S.A. Regulatory mutations of inositol biosynthesis in yeast:isolation of inositol excreting mutants. Genetics. 100:1982;19-33.
42. Lyons T.J., Gasch A.P., Gaither L.A., Botstein D., Brown P.O., Eide D.J. Genome-wide characterization of the Zap1p zinc-responsive regulon in yeast. Proc. Natl. Acad. Sci. U. S. A. 97:2000;7957-7962.
43. Yuan D.S. Zinc-regulated genes in Saccharomyces cerevisiae revealed by transposon tagging. Genetics. 156:2000;45-58.
44. Vallee B.L., Falchuk K.H. The biochemical basis of zinc physiology. Physiol. Rev. 73:1993;79-118.
45. Schwabe J.W., Klug A. Zinc mining for protein domains [news; comment]. Nat. Struct. Biol. 1:1994;345-349.
46. Guerinot M.L., Eide D. Zeroing in on zinc uptake in yeast and plants. Curr. Opin. Plant Biol. 2:1999;244-249.
47. Nies D.H., Silver S. Ion efflux systems involved in bacterial metal resistances. J. Ind. Microbiol. 14:1995;186-199.
48. Palmiter R.D., Findley S.D. Cloning and functional characterization of a mammalian zinc transporter that confers resistance to zinc. EMBO J. 14:1995;639-649.
49. Palmiter R.D. The elusive function of metallothioneins. Proc. Natl. Acad. Sci. U. S. A. 95:1998;8428-8430.
50. Zhao H., Eide D. The yeast ZRT1 gene encodes the zinc transporter protein of a high-affinity uptake system induced by zinc limitation. Proc. Natl. Acad. Sci. U. S. A. 93:1996;2454-2458.
51. Zhao H., Eide D. The ZRT2 gene encodes the low affinity zinc transporter in Saccharomyces cerevisiae. J. Biol. Chem. 271:1996;23203-23210.
52. Zhao H., Butler E., Rodgers J., Spizzo T., Duesterhoeft S., Eide D. Regulation of zinc homeostasis in yeast by binding of the ZAP1 transcriptional activator to zinc-responsive promoter elements. J. Biol. Chem. 273:1998;28713-28720.
53. MacDiarmid C.W., Gaither L.A., Eide D. Zinc transporters that regulate vacuolar zinc storage in Saccharomyces cerevisiae. EMBO J. 19:2000;2845-2855.
54. Zhao H., Eide D.J. Zap1p, a metalloregulatory protein involved in zinc-responsive transcriptional regulation in Saccharomyces cerevisiae. Mol. Cell Biol. 17:1997;5044-5052.
55. Carman G.M., Henry S.A. Phospholipid biosynthesis in yeast. Annu. Rev. Biochem. 58:1989;635-669.
56. Paltauf F., Kohlwein S.D., Henry S.A. Regulation and compartmentalization of lipid synthesis in yeast. Jones E.W., Pringle J.R., Broach J.R. The Molecular Biology of the Yeast Saccharomyces: Metabolism and Gene Expression. 1992;415-500 Cold Spring Harbor, New York.
57. Greenberg M.L., Lopes J.M. Genetic regulation of phospholipid biosynthesis in Saccharomyces cerevisiae. Microbiol. Rev. 60:1996;1-20.
58. Henry S.A., Patton-Vogt J.L. Genetic regulation of phospholipid metabolism: yeast as a model eukaryote. Prog. Nucleic Acid Res. 61:1998;133-179.
59. Carman G.M., Henry S.A. Phospholipid biosynthesis in the yeast Saccharomyces cerevisiae and interrelationship with other metabolic processes. Prog. Lipid Res. 38:1999;361-399.
60. Howe A.G., Zaremberg V., McMaster C.R. Cessation of growth to prevent cell death due to inhibition of phosphatidylcholine synthesis is impaired at 37 °C in Saccharomyces cerevisiae. J. Biol. Chem. 277:2002;44100-44107.
61. Nikoloff D.M., McGraw P., Henry S.A. The INO2 gene of Saccharomyces cerevisiae encodes a helix-loop-helix protein that is required for activation of phospholipid synthesis. Nucleic Acids Res. 20:1992;3253.
62. Hoshizaki D.K., Hill J.E., Henry S.A. The Saccharomyces cerevisiae INO4 gene encodes a small, highly basic protein required for derepression of phospholipid biosynthetic enzymes. J. Biol. Chem. 265:1990;4736-4745.
63. White M.J., Hirsch J.P., Henry S.A. The OPI1 gene of Saccharomyces cerevisiae, a negative regulator of phospholipid biosynthesis, encodes a protein containing polyglutamine tracts and a leucine zipper. J. Biol. Chem. 266:1991;863-872.
64. Kodaki T., Nikawa J., Hosaka K., Yamashita S. Functional analysis of the regulatory region of the yeast phosphatidylserine synthase gene, PSS. J. Bacteriol. 173:1991;7992-7995.
65. Lopes J.M., Hirsch J.P., Chorgo P.A., Schulze K.L., Henry S.A. Analyses of sequences in the INO1 promoter that are involved in its regulation by phospholipid precursors. Nucleic Acids Res. 19:1991;1687-1693.
66. Schuller H.J., Hahn A., Troster F., Schutz A., Schweizer E. Coordinate genetic control of yeast fatty acid synthase genes FAS1 and FAS2 by an upstream activation site common to genes involved in membrane lipid biosynthesis. EMBO J. 11:1992;107-114.
67. Schuller H.J., Richter K., Hoffmann B., Ebbert R., Schweizer E. DNA binding site of the yeast heteromeric Ino2p/Ino4p basic helix-loop-helix transcription factor: structural requirements as defined by saturation mutagenesis. FEBS Lett. 370:1995;149-152.
68. Hirsch J.P., Henry S.A. Expression of the Saccharomyces cerevisiae inositol-1-phosphate synthase (INO1) gene is regulated by factors that affect phospholipid synthesis. Mol. Cell. Biol. 6:1986;3320-3328.
69. Loewy B.S., Henry S.A. The INO2 and INO4 loci of Saccharomyces cerevisiae are pleiotropic regulatory genes. Mol. Cell. Biol. 4:1984;2479-2485.
70. Schwank S., Ebbert R., Rautenstrauss K., Schweizer E., Schuller H.J. Yeast transcriptional activator INO2 interacts as an Ino2p/Ino4p basic helix-loop-helix heteromeric complex with the inositol/choline-responsive element necessary for expression of phospholipid biosynthetic genes in Saccharomyces cerevisiae. Nucleic Acids Res. 23:1995;230-237.
71. Klig L.S., Homann M.J., Kohlwein S.D., Kelley M.J., Henry S.A., Carman G.M. Saccharomyces cerevisiae mutant with a partial defect in the synthesis of CDP-diacylglycerol and altered regulation of phospholipid biosynthesis. J. Bacteriol. 170:1988;1878-1886.
72. Kelley M.J., Bailis A.M., Henry S.A., Carman G.M. Regulation of phospholipid biosynthesis in Saccharomyces cerevisiae by inositol. Inositol is an inhibitor of phosphatidylserine synthase activity. J. Biol. Chem. 263:1988;18078-18085.
73. Oshiro J., Han G.-S., Iwanyshyn W.M., Conover K., Carman G.M. Regulation of the yeast DPP1-encoded diacylglycerol pyrophosphate phosphatase by transcription factor Gis1p. J. Biol. Chem. 2003;31495-31503.
74. Pedruzzi I., Bürckert N., Egger P., De Virgilio C. Saccharomyces cerevisiae Ras/cAMP pathway controls post-diauxic shift element-dependent transcription through the zinc finger protein Gis1. EMBO J. 19:2000;2569-2579.
75. Boorstein W.R., Craig E.A. Regulation of a yeast HSP70 gene by a cAMP responsive transcriptional control element. EMBO J. 9:1990;2543-2553.
76. Jang Y.K., Wang L., Sancar G.B. RPH1 and GIS1 are damage-responsive repressors of PHR1. Mol. Cell Biol. 19:1999;7630-7638.