Changes in MM-CK Conformational Mobility upon Formation of the ADP-Mg 2+-NO3--Creatine Transition State Analogue Complex As Detected by Hydrogen/Deuterium Exchange

Biochemistry

Volumn 42, Issue 46, 2003, Pages 13596-13604

  Mazon, Hortense ^a   Marcillat, Olivier ^a   Forest, Eric ^b   Vial, Christian ^a  

^a UNIVERSITÉ LYON 1   (France)

^b INSTITUT DE BIOLOGIE STRUCTURALE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL BONDS; DEUTERIUM; ENZYMES; HYDROGEN; MASS SPECTROMETRY; SUBSTRATES;

LIGANDS; PROTEOLYSIS;

BIOCHEMISTRY;

ADENOSINE DIPHOSPHATE; CREATINE KINASE MM; DEUTERIUM; HYDROGEN; ISOENZYME; MAGNESIUM ION; NITRATE;

ARTICLE; BINDING SITE; CATALYSIS; CHEMICAL LABELING; COMPLEX FORMATION; ENZYME ACTIVE SITE; ENZYME STRUCTURE; ENZYME SUBSTRATE; ION EXCHANGE; LIGAND BINDING; MASS SPECTROMETRY; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN DOMAIN;

ADENOSINE DIPHOSPHATE; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CREATINE; CREATINE KINASE; DEUTERIUM EXCHANGE MEASUREMENT; HYDROGEN; ISOENZYMES; MAGNESIUM; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUSCLES; NITRATES; PEPSIN A; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; RABBITS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 0344391933     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi035208m     Document Type: Article

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