Absence of Factor V Leiden, thrombomodulin and prothrombin gene variants in Black South African women with pre-eclampsia and eclampsia

BJOG: An International Journal of Obstetrics and Gynaecology

Volumn 110, Issue 3, 2003, Pages 327-328

  Hira, B ^a,b   Pegoraro, R J ^b   Rom, L ^b   Moodley, J ^a,b  

^a SOUTH AFRICAN MEDICAL RESEARCH COUNCIL   (South Africa)

^b UNIVERSITY OF KWAZULU NATAL   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 5 LEIDEN; PROTHROMBIN; THROMBOMODULIN;

ADULT; ALLELE; ARTICLE; BLOOD PRESSURE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE ASSOCIATION; ECLAMPSIA; FEMALE; GENE LOCUS; GENETIC ANALYSIS; GENETIC VARIABILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MUTATION; PREECLAMPSIA; PREGNANCY; PRIORITY JOURNAL; SOUTH AFRICA;

EID: 0344255725     PISSN: 14700328     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-0528.2003.01090.x     Document Type: Article

References (5)

1. Kupfermic M.J., Fait G., Many Aet al. Severe pre-eclampsia and high frequency of genetic thrombophilic mutations. Obstet Gynecol. 96:2000;45-49.
2. Kobashi G., Yamada H., Asano Tet al. The factor V Leiden mutation is not a common cause of pregnancy-induced hypertension in Japan. Semin Thromb Hemost. 25:1999;487-489.
3. Nakabayashi M., Yamamoto S., Suziki K. Analysis of thrombomodulin gene polymorphism in women with severe early onset pre-eclampsia. Semin Thromb Hemost. 25:1999;473-479.
4. Chikosi A.B., Moodley J., Pegoraro RJet al. 5,10-Methylenetetrahydrofolate reductase polymorphism in Black South African women with pre-eclampsia. Br J Obstet Gynaecol. 106:1999;1219-1220.
5. Poort S.R., Rosendaal F.R., Reitoma PHet al. A common genetic variation in the 3′ untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis. Blood. 15:1996;3698-3703.