5,10 methylenetetrahydrofolate reductase polymorphism in black South African women with pre-eclampsia

BJOG: An International Journal of Obstetrics and Gynaecology

Volumn 106, Issue 11, 1999, Pages 1219-1220

  Chikosi, A B ^a   Moodley, J ^a   Pegoraro, R J ^b   Lanning, P A ^b   Rom, L ^b  

^a MRC UN Pregnancy Hypertension Research Unit   (South Africa)

^b UNIVERSITY OF NATAL   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2);

ADULT; ALLELE; ARTICLE; CONTROLLED STUDY; FEMALE; GENE MUTATION; GENETIC POLYMORPHISM; HUMAN; MAJOR CLINICAL STUDY; NEGRO; PREECLAMPSIA; PRIORITY JOURNAL; SOUTH AFRICA;

AFRICA; AFRICA SOUTH OF THE SAHARA; BIOLOGY; BLACKS--WOMEN; CULTURAL BACKGROUND; DEMOGRAPHIC FACTORS; DEVELOPING COUNTRIES; DISEASES; ENGLISH SPEAKING AFRICA; ENZYMES; ENZYMES AND ENZYME INHIBITORS; ETHNIC GROUPS; GENETICS; PHYSIOLOGY; POPULATION; POPULATION CHARACTERISTICS; PREECLAMPSIA; PREGNANCY COMPLICATIONS; PREGNANT WOMEN; RESEARCH REPORT; SOUTH AFRICA; SOUTHERN AFRICA; WOMEN;

ADOLESCENT; ADULT; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); OXIDOREDUCTASES ACTING ON CH-NH GROUP DONORS; POLYMORPHISM, GENETIC; PRE-ECLAMPSIA; PREGNANCY; SOUTH AFRICA;

EID: 0032697849     PISSN: 14700328     EISSN: 14710528     Source Type: Journal    
DOI: 10.1111/j.1471-0528.1999.tb08152.x     Document Type: Article

References (6)

1. Frosst P, Blom Hs, Milos R et al. A candidate genetic risk factor for vascular disease: A common mutation in methylenetetrahydrofolate reductase. Nat Genet 1995; 10: 111-113.
2. Sohda S, Arimani T, Hamada H, Yamada N, Hamaguchi H, Kubo T. Methylenetetrahydrofolate reductase polymorphism and pre-eclampsia. J Med Gen 1997; 34: 525-526.
3. Grandone E, Margaglione M, Colizzo D et al. Factor V Leiden, C→ TMTHFR polymorphism and genetic susceptibility to pre-eclampsia. Thromb Haem 1997; 77: 1052-1054.
4. Nagy B, Rigo J, Toth T, Karadi I, Romics L, Papp Z. Methylenetetrahydrofolate reductase polymorphism in healthy pregnant and preeclamptic women. Clin Chem 1998; 44: A15.
5. Franco RF, Araujo AG, Geirreiro IF, Zago MA. Analysis of the 677 C→ T mutation of the methylenetetrahydrofolate reductase gene in different ethnic groups. Thromb Haem 1998; 79: 119-121.
6. Moodley J, Rout CC. Maternal deaths associated with hypertensive disorders of pregnancy. S Afr Med J 1997; 87: 793-798.