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Volumn 8, Issue 1, 2003, Pages 1-14

Helicobacter pylori CagA containing ITAM-like sequences localized to lipid rafts negatively regulates VacA-induced signaling in vivo

Author keywords

CagA; CagA induced vesicle; G protein coupled receptor kinase interactor 1 (GIT1) Cool associated tyrosine phosphorylated 1(Cat1); Helicobacter pylori; Immunoreceptor tyrosine based activation motif (ITAM) like sequences

Indexed keywords

ANTIBODY; CAGA PROTEIN; G PROTEIN COUPLED RECEPTOR KINASE; G PROTEIN COUPLED RECEPTOR KINASE INTERACTOR 1; LIPID; MONOCLONAL ANTIBODY; PHOSPHATASE; POLYCLONAL ANTIBODY; PROTEIN; PROTEINASE; PY ANTIBODY; RECEPTOR TYPE PROTEIN TYROSINE PHOSPHATASE; TYROSINE; UNCLASSIFIED DRUG; VACUOLATING TOXIN;

EID: 0344211475     PISSN: 10834389     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-5378.2003.00118.x     Document Type: Article
Times cited : (30)

References (30)
  • 1
    • 0027173990 scopus 로고
    • Molecular characterization of 128-kDa immunodominant antigen of Helicobacter pylori associated with cytotoxicity and duodenal ulcer
    • Covacci A, Censini S, Bugnoli M, et al. Molecular characterization of 128-kDa immunodominant antigen of Helicobacter pylori associated with cytotoxicity and duodenal ulcer. Proc Natl Acad Sci USA, 1993;90:5791-5.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 5791-5795
    • Covacci, A.1    Censini, S.2    Bugnoli, M.3
  • 2
    • 0029043658 scopus 로고
    • Infection with Helicobacter pylori strains possessing cagA is associated with an increased risk of developing adenocarcinoma of the stomach
    • Blaser MJ, Perez-Perez GI, Kleanthous H, et al. Infection with Helicobacter pylori strains possessing cagA is associated with an increased risk of developing adenocarcinoma of the stomach. Cancer Res, 1995;55:2111-5.
    • (1995) Cancer Res , vol.55 , pp. 2111-2115
    • Blaser, M.J.1    Perez-Perez, G.I.2    Kleanthous, H.3
  • 5
    • 0345421139 scopus 로고    scopus 로고
    • Disease specific Helicobacter pylori virulence factors. The role of cagA, vacA, iceA, babA2 along or in combination
    • Hunt RH, Tytgat GNJ, eds. Dordrecht, Germany: Kluwer Academic Publishers
    • Yamaoka Y, Graham DY. Disease specific Helicobacter pylori virulence factors. the role of cagA, vacA, iceA, babA2 along or in combination. In: Helicobacter pylori. Basic Mechanisms to Clinical Cure. Hunt RH, Tytgat GNJ, eds. Dordrecht, Germany: Kluwer Academic Publishers. 2000: pp. 37-42.
    • (2000) Helicobacter Pylori. Basic Mechanisms to Clinical Cure , pp. 37-42
    • Yamaoka, Y.1    Graham, D.Y.2
  • 6
    • 0030892896 scopus 로고    scopus 로고
    • MALT-type lymphoma of the stomach is associated with Helicobacter pylori strains expressing the CagA protein
    • Eck M, Schmausser B, Haas R, Greiner A, Czub S, Muller-Hermelink HK. MALT-type lymphoma of the stomach is associated with Helicobacter pylori strains expressing the CagA protein. Gastroenterology, 1997;112:1482-6.
    • (1997) Gastroenterology , vol.112 , pp. 1482-1486
    • Eck, M.1    Schmausser, B.2    Haas, R.3    Greiner, A.4    Czub, S.5    Muller-Hermelink, H.K.6
  • 7
    • 0034695875 scopus 로고    scopus 로고
    • Helicobacter pylori CagA protein can be tyrosine phosphorylated in gastric epithelial cells
    • Asahi M, Azumu T, Ito S, et al. Helicobacter pylori CagA protein can be tyrosine phosphorylated in gastric epithelial cells. J Exp Med, 2000;191:593-602.
    • (2000) J Exp Med , vol.191 , pp. 593-602
    • Asahi, M.1    Azumu, T.2    Ito, S.3
  • 8
    • 0033953359 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of the Helicobacter pylori CagA after cag-driven host cell translocation
    • Stein M, Rappuoli R, Covacci A. Tyrosine phosphorylation of the Helicobacter pylori CagA after cag-driven host cell translocation. Proc Natl Acad Sci USA, 2000;97:1263-8.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 1263-1268
    • Stein, M.1    Rappuoli, R.2    Covacci, A.3
  • 9
    • 17344379177 scopus 로고    scopus 로고
    • Translocation of Helicobacter pylori CagA into gastric epithelial cells by type IV secretion
    • Odenbreit S, Puls J, Sedlmaier B, Gerland E, Fischer W, Hass R. Translocation of Helicobacter pylori CagA into gastric epithelial cells by type IV secretion. Science, 2000;287:1497-500.
    • (2000) Science , vol.287 , pp. 1497-1500
    • Odenbreit, S.1    Puls, J.2    Sedlmaier, B.3    Gerland, E.4    Fischer, W.5    Hass, R.6
  • 10
    • 0033456273 scopus 로고    scopus 로고
    • Altered states: Involvement of phosphorylated CagA in the induction of host cellular changes by Helicobacter pylori
    • Segal ED, Cha J, Lo J, Falkow S, Tompkins LS. Altered states: Involvement of phosphorylated CagA in the induction of host cellular changes by Helicobacter pylori. Proc Natl Acad Sci USA, 1999;96:14559-69.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 14559-14569
    • Segal, E.D.1    Cha, J.2    Lo, J.3    Falkow, S.4    Tompkins, L.S.5
  • 11
    • 0034042694 scopus 로고    scopus 로고
    • Translocation of the Helicobacter pylori CagA protein in gastric epithelial cells by a type IV secretion apparatus
    • Backert S, Ziska E, Brinkman V, et al. Translocation of the Helicobacter pylori CagA protein in gastric epithelial cells by a type IV secretion apparatus. Cellular Microbiol, 2000;2:155-64.
    • (2000) Cellular Microbiol , vol.2 , pp. 155-164
    • Backert, S.1    Ziska, E.2    Brinkman, V.3
  • 12
    • 0025349492 scopus 로고
    • Helicobacter pylori and the pathogenesis of gastroduodenal inflammation
    • Blaser MJ. Helicobacter pylori and the pathogenesis of gastroduodenal inflammation. J Infect Dis, 1990;161:626-33.
    • (1990) J Infect Dis , vol.161 , pp. 626-633
    • Blaser, M.J.1
  • 13
    • 0025945933 scopus 로고
    • Helicobacter pylori infection and the risk of gastric carcinoma
    • Parsonnet J, Friedman GD, Vandersten DP, et al. Helicobacter pylori infection and the risk of gastric carcinoma. N Engl J Med, 1991;325:1127-31.
    • (1991) N Engl J Med , vol.325 , pp. 1127-1131
    • Parsonnet, J.1    Friedman, G.D.2    Vandersten, D.P.3
  • 14
    • 0028230879 scopus 로고
    • Helicobacter pylori infection and gastric lymphoma
    • Parsonnet J, Hansen S, Rodriguez L, et al. Helicobacter pylori infection and gastric lymphoma. N Engl J Med, 1994;330:1267-71.
    • (1994) N Engl J Med , vol.330 , pp. 1267-1271
    • Parsonnet, J.1    Hansen, S.2    Rodriguez, L.3
  • 15
    • 0035162820 scopus 로고    scopus 로고
    • Phosphorylation of tyrosine 972 of the Helicobacter pylori CagA protein is essential for induction of a scattering phenotype in gastric epithelial cells
    • Backert S, Moese S, Selbach M, Brinkmann V, Meyer TF. Phosphorylation of tyrosine 972 of the Helicobacter pylori CagA protein is essential for induction of a scattering phenotype in gastric epithelial cells. Cellular Microbiol, 2001;42:631-44.
    • (2001) Cellular Microbiol , vol.42 , pp. 631-644
    • Backert, S.1    Moese, S.2    Selbach, M.3    Brinkmann, V.4    Meyer, T.F.5
  • 16
    • 0036227053 scopus 로고    scopus 로고
    • c-Src/Lyn kinases active Helicobacter pylori CagA through tyrosine phosphorylation of the EPIYA motifs
    • Stein M, Bagnoli F, Halenbeck R, Rappuoli R, Fantl WJ, Covacci A. c-Src/Lyn kinases active Helicobacter pylori CagA through tyrosine phosphorylation of the EPIYA motifs. Cellular Microbiol, 2002;43:971-80.
    • (2002) Cellular Microbiol , vol.43 , pp. 971-980
    • Stein, M.1    Bagnoli, F.2    Halenbeck, R.3    Rappuoli, R.4    Fantl, W.J.5    Covacci, A.6
  • 17
    • 0037169076 scopus 로고    scopus 로고
    • SHP-2 Tyrosine phosphatase as an intracellular target of Helicobacter pylori CagA protein
    • Higashi H, Tsutsumi R, Muto S, et al. SHP-2 Tyrosine phosphatase as an intracellular target of Helicobacter pylori CagA protein. Science, 2001;295:683-6.
    • (2001) Science , vol.295 , pp. 683-686
    • Higashi, H.1    Tsutsumi, R.2    Muto, S.3
  • 18
    • 0036230282 scopus 로고    scopus 로고
    • Activation of Helicobacter pylori CagA by tyrosine phosphorylation is essential for dephosphorylation of host cell proteins in gastric epithelial cells
    • Puls J, Fischer W, Hass R. Activation of Helicobacter pylori CagA by tyrosine phosphorylation is essential for dephosphorylation of host cell proteins in gastric epithelial cells. Cellular Microbiol, 2002;43:961-9.
    • (2002) Cellular Microbiol , vol.43 , pp. 961-969
    • Puls, J.1    Fischer, W.2    Hass, R.3
  • 19
    • 0024980981 scopus 로고
    • Antigen receptor tail clue
    • Reth M. Antigen receptor tail clue. Nature, 1989;338:383-4.
    • (1989) Nature , vol.338 , pp. 383-384
    • Reth, M.1
  • 20
    • 0031577601 scopus 로고    scopus 로고
    • Helicobacter pylori vacuolating cytotoxin binds to the 140-kDa protein in human gastric cancer cell line, AZ-521 and AGS
    • Yahiro K, Niidome T, Hatakeyama T, et al. Helicobacter pylori vacuolating cytotoxin binds to the 140-kDa protein in human gastric cancer cell line, AZ-521 and AGS. Biochem Biophys Res Commun, 1997;238:629-32.
    • (1997) Biochem Biophys Res Commun , vol.238 , pp. 629-632
    • Yahiro, K.1    Niidome, T.2    Hatakeyama, T.3
  • 21
    • 0037072947 scopus 로고    scopus 로고
    • Association of Helicobacter pylori vacuolating toxin (VacA) with lipid rafts
    • Schraw W, Li Y, McClain MS, van der Goot FG, Cover TL. Association of Helicobacter pylori vacuolating toxin (VacA) with lipid rafts. Biol Chem, 2002;277:34642-50.
    • (2002) Biol Chem , vol.277 , pp. 34642-34650
    • Schraw, W.1    Li, Y.2    McClain, M.S.3    Van der Goot, F.G.4    Cover, T.L.5
  • 22
    • 0035810942 scopus 로고    scopus 로고
    • Identification of GIT1/Cat-1 as a substrate molecule of protein tyrosine phosphataseζ/β by the yeast substrate-trapping system
    • Kawachi H, Fujikawa A, Maeda N, Noda M. Identification of GIT1/Cat-1 as a substrate molecule of protein tyrosine phosphataseζ/β by the yeast substrate-trapping system. Proc Natl Acad Sci USA, 2001;98:6593-8.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 6593-6598
    • Kawachi, H.1    Fujikawa, A.2    Maeda, N.3    Noda, M.4
  • 24
    • 0027749278 scopus 로고
    • Attachment of Helicobacter pylori to human gastric epithelium mediated by blood group antigens
    • Boren T, Falk P, Roth KA, Larson G, Normark S. Attachment of Helicobacter pylori to human gastric epithelium mediated by blood group antigens. Science 1993;262:1892-5.
    • (1993) Science , vol.262 , pp. 1892-1895
    • Boren, T.1    Falk, P.2    Roth, K.A.3    Larson, G.4    Normark, S.5
  • 25
    • 0033607258 scopus 로고    scopus 로고
    • Clinical relevance of the Helicobacter pylori gene for blood-group antigen-binding adhesion
    • Markus G, Norbert L, Nina N, et al. Clinical relevance of the Helicobacter pylori gene for blood-group antigen-binding adhesion. Proc Natl Acad Sci USA 1999;96:12778-83.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 12778-12783
    • Markus, G.1    Norbert, L.2    Nina, N.3
  • 26
    • 0036721518 scopus 로고    scopus 로고
    • NSAIDs counteract H. pylori VacA toxin-induced cell vacuolation in MKN 28 gastric mucosal cells
    • Ricci V, Manzo BA, Tuccillo C, et al. NSAIDs counteract H. pylori VacA toxin-induced cell vacuolation in MKN 28 gastric mucosal cells. Am J Physiol Gastrointest Liver Physiol 2002;283:G511-20.
    • (2002) Am J Physiol Gastrointest Liver Physiol , vol.283
    • Ricci, V.1    Manzo, B.A.2    Tuccillo, C.3
  • 27
    • 0033002855 scopus 로고    scopus 로고
    • Phosphorylation of tyrosine 474 of the enteropathogenic Esherichia coli (EPEC) Tir receptor molecule is essential for actin nucleating activity and is preceded by additional host modifications
    • Kenny B. Phosphorylation of tyrosine 474 of the enteropathogenic Esherichia coli (EPEC) Tir receptor molecule is essential for actin nucleating activity and is preceded by additional host modifications. Mol Microbiol, 1999;31:1229-41.
    • (1999) Mol Microbiol , vol.31 , pp. 1229-1241
    • Kenny, B.1
  • 28
    • 0035059331 scopus 로고    scopus 로고
    • Recruitment of cytoskeletal and signaling proteins to Enteropathogenic and Enterohemorrhagic Esherichia coli pedestals
    • Goosney DL, DeVinney R, Finlay BB. Recruitment of cytoskeletal and signaling proteins to Enteropathogenic and Enterohemorrhagic Esherichia coli pedestals. Infect Immun, 2001;69:3315-22.
    • (2001) Infect Immun , vol.69 , pp. 3315-3322
    • Goosney, D.L.1    DeVinney, R.2    Finlay, B.B.3
  • 29
    • 0037195107 scopus 로고    scopus 로고
    • Biological activity of the Helicobacter pylori virulence factor CagA is determined by variation in the tyrosine phosphorylation sites
    • Higashi H, Tsutsumi R, Fujita A, et al. Biological activity of the Helicobacter pylori virulence factor CagA is determined by variation in the tyrosine phosphorylation sites. Proc Natl Acad Sci USA, 2002;99:14428-33.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 14428-14433
    • Higashi, H.1    Tsutsumi, R.2    Fujita, A.3
  • 30
    • 0032815340 scopus 로고    scopus 로고
    • Relationship between subtypes of the cagA-3′ repeat region, gastric histology, and susceptibility to low pH
    • Yamaoka Y, El-Zimaity HMT, Gutierrez O, et al. Relationship between subtypes of the cagA-3′ repeat region, gastric histology, and susceptibility to low pH. Gastroenterology, 1999;117:342-9.
    • (1999) Gastroenterology , vol.117 , pp. 342-349
    • Yamaoka, Y.1    El-Zimaity, H.M.T.2    Gutierrez, O.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.