Melatonergic properties of the (+)- and (-)-enantiomers of N-(4-methoxy- 2,3-dihydro-1H-phenalen-2-yl)amide derivatives

Journal of Medicinal Chemistry

Volumn 42, Issue 6, 1999, Pages 1100-1105

  Jellimann, Carole ^a   Mathé Allainmat, Monique ^a   Andrieux, Jean ^a   Renard, Pierre ^b   Delagrange, Philippe ^c   Langlois, Michel ^a  

^a CNRS   (France)

^b ADIR   (France)

^c INSTITUT DE RECHERCHES INTERNATIONALES SERVIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

2 IODOMELATONIN; 4 METHOXY 2,3 DIHYDRO 1H PHENALENE 2 CARBOXYLIC ACID; AGOMELATINE; AMIDE; HORMONE RECEPTOR BLOCKING AGENT; IODINE 125; MELATONIN; MELATONIN RECEPTOR; N (4 METHOXY 2,3 DIHYDRO 1H PHENALEN 2 YL) AMIDE DERIVATIVE; N (4 METHOXY 2,3 DIHYDRO 1H PHENALEN 2 YL)ACETAMIDE; N (4 METHOXY 2,3 DIHYDRO 1H PHENALEN 2 YL)BUTANAMIDE; N (4 METHOXY 2,3 DIHYDRO 1H PHENALEN 2 YL)PROPANAMIDE; N [2 (2,7 DIMETHOXYNAPHTH 1 YL)ETHYL]ACETAMIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; CHICKEN; CONTROLLED STUDY; DRUG POTENCY; DRUG SYNTHESIS; ENANTIOMER; MELANOPHORE; NONHUMAN; SKIN COLOR; TADPOLE; XENOPUS LAEVIS;

ACETAMIDES; ANIMALS; BRAIN; CHICKENS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; LIGANDS; MELATONIN; PHENALENES; POLYCYCLIC COMPOUNDS; RADIOLIGAND ASSAY; RECEPTORS, CELL SURFACE; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, MELATONIN; SKIN; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; XENOPUS LAEVIS;

EID: 0344197160     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9804937     Document Type: Article

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