Pharmacokinetics and pharmacodynamics of topiramate

Journal of Child Neurology

Volumn 15, Issue SUPPL. 1, 2000, Pages

  Bourgeois, B F D ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; CALCIUM CHANNEL; CARBAMAZEPINE; CARBONATE DEHYDRATASE; CARBONATE DEHYDRATASE INHIBITOR; DIGOXIN; KAINIC ACID; ORAL CONTRACEPTIVE AGENT; PHENYTOIN; SODIUM CHANNEL; TOPIRAMATE;

ADOLESCENT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANOREXIA; ARTERY EMBOLISM; ARTICLE; ATTENTION DEFICIT DISORDER; BRAIN ISCHEMIA; CENTRAL NERVOUS SYSTEM DISEASE; CHILD; CONFUSION; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG ELIMINATION; DRUG HALF LIFE; DRUG MECHANISM; DRUG METABOLISM; DRUG PROTEIN BINDING; DRUG SAFETY; EPILEPSY; EPILEPTIC STATE; EPILEPTOGENESIS; FATIGUE; HUMAN; MIDDLE CEREBRAL ARTERY; MOUSE; NEPHROLITHIASIS; NEUROPROTECTION; NEWBORN; NONHUMAN; PHARMACODYNAMICS; PHARMACOKINETICS; PRIORITY JOURNAL; RAT; SIDE EFFECT; SOMNOLENCE; THOUGHT DISORDER; WEIGHT REDUCTION;

EID: 0034469918     PISSN: 08830738     EISSN: None     Source Type: Journal    
DOI: 10.1177/0883073800015001s06     Document Type: Article

References (34)

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3. A double-blind, randomized trial of topiramate in Lennox-Gastaut syndrome
4. A pilot study of topiramate in the treatment of infantile spasms
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6. Nephrolithiasis during treatment with topiramate, abstract
7. Topiramate and metabolic acidosis
8. Topiramate and metabolic acidosis in pediatric epilepsy, abstract
9. Pharmacokinetics and metabolism of topiramate
10. Drug interaction profile of topiramate
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12. Pharmacokinetic properties of current antiepileptic drugs: What improvements are needed?
13. Effects of topiramate on the pharmacokinetics of an oral contraceptive containing norethindrone and ethynil estradiol in patients with epilepsy
14. Digoxin and topiramate drug interaction study in male volunteers, abstract
15. A study of topiramate pharmacokinetics and tolerability in children with epilepsy
16. Topiramate pharmacokinetics in infants
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18. The effect of food on the oral bioavailability of topiramate from an investigational pediatric sprinkle formulation, abstract
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20. Topiramate blocks kainate-evoked cobalt influx into cultured neurons
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23. Effects of topiramate on sustained repetitive firing and spontaneous recurrent seizure discharges in cultured hippocampal neurons
24. Effects of topiramate on sodium-dependent action potential firing by mouse spinal cord neurons in cell culture
25. Modulation of high-voltage-activated calcium channels in dentate granule cells by topiramate
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31. Enhanced neuroprotection and reduced hemorrhagic incidence in focal cerebral ischemia of rat by low dose combination therapy of urokinase and topiramate
32. Topiramate blocks acute and chronic epileptogenesis in a rat model of perinatal hypoxic encephalopathy, abstract
33. Topiramate reduces neuronal injury after experimental status epilepticus
34. Protective effect of topiramate against hippocampal neuronal damage after global ischemia in the gerbils