메뉴 건너뛰기




Volumn 163, Issue 4, 1999, Pages 2089-2097

Toxoplasma gondii and Schistosoma mansoni synergize to promote hepatocyte dysfunction associated with high levels of plasma TNF-α and early death in C57BL/6 mice

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GAMMA INTERFERON; IMMUNOGLOBULIN E; NITRIC OXIDE; TUMOR NECROSIS FACTOR ALPHA;

EID: 0344131392     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (62)

References (48)
  • 1
    • 0031570939 scopus 로고    scopus 로고
    • IL-4 protects against TNF-α-mediated cachexia and death during acute schistosomiasis
    • Rosa Brunet, L., F. D. Finkelman, A. W. Cheever, M. A. Kopf, and E. J. Pearce. 1997. IL-4 protects against TNF-α-mediated cachexia and death during acute schistosomiasis. J. Immunol 159:777.
    • (1997) J. Immunol , vol.159 , pp. 777
    • Rosa Brunet, L.1    Finkelman, F.D.2    Cheever, A.W.3    Kopf, M.A.4    Pearce, E.J.5
  • 2
    • 0031736936 scopus 로고    scopus 로고
    • Regulation and function of T cell-mediated immunity during Toxoplasma gondii infection
    • Denkers, E. Y., and R. T. Gazzinelli. 1998. Regulation and function of T cell-mediated immunity during Toxoplasma gondii infection. Clin. Microbiol. Rev. 11:569.
    • (1998) Clin. Microbiol. Rev. , vol.11 , pp. 569
    • Denkers, E.Y.1    Gazzinelli, R.T.2
  • 3
    • 0029584424 scopus 로고
    • Role of IL-12 in the induction of cell-mediated immunity to Toxoplasma gondii
    • Scharton-Kersten. T., E. Y. Denkers, R. T. Gazzinelli, and A. Sher. 1995. Role of IL-12 in the induction of cell-mediated immunity to Toxoplasma gondii. Res. Immunol. 146:539.
    • (1995) Res. Immunol. , vol.146 , pp. 539
    • Scharton-Kersten, T.1    Denkers, E.Y.2    Gazzinelli, R.T.3    Sher, A.4
  • 5
    • 0027177008 scopus 로고
    • IL-12: Initiation cytokine for cell-mediated immunity
    • Scott, P. 1993. IL-12: initiation cytokine for cell-mediated immunity. Science 260:496.
    • (1993) Science , vol.260 , pp. 496
    • Scott, P.1
  • 6
    • 0026076742 scopus 로고
    • Human T cell clone identifies a potentially protective 54-kDa protein antigen of Toxoplasma gondii cloned and expressed in Escherichia coli
    • Saavedra, R., F. de Meuter, J.-L. Decourt, and P. Herion. 1991. Human T cell clone identifies a potentially protective 54-kDa protein antigen of Toxoplasma gondii cloned and expressed in Escherichia coli. J. Immunol. 147:1975.
    • (1991) J. Immunol. , vol.147 , pp. 1975
    • Saavedra, R.1    De Meuter, F.2    Decourt, J.-L.3    Herion, P.4
  • 7
    • 0026091204 scopus 로고
    • Tumor necrosis factor-α triggers antitoxoplasmal activity in IFN-γ primed macrophages
    • Sibley, L. D., L. B. Adams, A. Y. Fukutomi, and J. L. Krahenbuhl. 1991. Tumor necrosis factor-α triggers antitoxoplasmal activity in IFN-γ primed macrophages. J. Immunol. 147:2340.
    • (1991) J. Immunol. , vol.147 , pp. 2340
    • Sibley, L.D.1    Adams, L.B.2    Fukutomi, A.Y.3    Krahenbuhl, J.L.4
  • 8
    • 0027208743 scopus 로고
    • Acute cerebral toxoplasmosis is induced by in vivo neutralization of TNF-α and correlates with the down-regulated expression of inducible nitric oxide synthase and other markers of macrophage activation
    • Gazzinelli, R. T., I. Eltoum, T. A. Wynn, and A. Sher. 1993. Acute cerebral toxoplasmosis is induced by in vivo neutralization of TNF-α and correlates with the down-regulated expression of inducible nitric oxide synthase and other markers of macrophage activation. J. Immunol. 151:3672.
    • (1993) J. Immunol. , vol.151 , pp. 3672
    • Gazzinelli, R.T.1    Eltoum, I.2    Wynn, T.A.3    Sher, A.4
  • 9
    • 0026805989 scopus 로고
    • The microbicidal activity of interferon-γ-treated macrophages against Trypanosoma cruzi involves an L-arginine-dependent, nitrogen oxide-mediated mechanism inhibitable by interleukin-10 and transforming growth factor-β
    • Gazzinelli, R. T., I. P. Oswald, S. Hieny, S. James, and A. Sher. 1992. The microbicidal activity of interferon-γ-treated macrophages against Trypanosoma cruzi involves an L-arginine-dependent, nitrogen oxide-mediated mechanism inhibitable by interleukin-10 and transforming growth factor-β. Eur. J. Immunol. 22:2501.
    • (1992) Eur. J. Immunol. , vol.22 , pp. 2501
    • Gazzinelli, R.T.1    Oswald, I.P.2    Hieny, S.3    James, S.4    Sher, A.5
  • 11
    • 0030294163 scopus 로고    scopus 로고
    • In the absence of endogenous IFN-γ mice develop unimpaired IL-12 responses to Toxoplasma gondii while failing to control acute infection
    • Scharton-Kersten, T. M., T. A. Wynn, E. Y. Denkers, S. Bala, L. Showe, E. Grunvald, S. Hieny, R. T. Gazzinelli, and A. Sher. 1996. In the absence of endogenous IFN-γ mice develop unimpaired IL-12 responses to Toxoplasma gondii while failing to control acute infection. J. Immunol. 157:4045.
    • (1996) J. Immunol. , vol.157 , pp. 4045
    • Scharton-Kersten, T.M.1    Wynn, T.A.2    Denkers, E.Y.3    Bala, S.4    Showe, L.5    Grunvald, E.6    Hieny, S.7    Gazzinelli, R.T.8    Sher, A.9
  • 12
    • 0023895411 scopus 로고
    • Interferon-γ: The major mediator of resistance against Toxoplasma gondii
    • Suzuki, Y., M. A. Orellana, R. D. Schreiber, and J. S. Remington. 1988. Interferon-γ: the major mediator of resistance against Toxoplasma gondii. Science 240:516.
    • (1988) Science , vol.240 , pp. 516
    • Suzuki, Y.1    Orellana, M.A.2    Schreiber, R.D.3    Remington, J.S.4
  • 13
    • 0024438401 scopus 로고
    • Importance of endogenous IFN-γ for the prevention of toxoplasmic encephalitis in mice
    • Suzuki, Y., F. K. Conley, and J. S. Remington. 1989. Importance of endogenous IFN-γ for the prevention of toxoplasmic encephalitis in mice. J. Immunol. 143: 2045.
    • (1989) J. Immunol. , vol.143 , pp. 2045
    • Suzuki, Y.1    Conley, F.K.2    Remington, J.S.3
  • 14
  • 15
    • 0026691883 scopus 로고
    • A protective role for endogenous tumor necrosis factor in Toxoplasma gondii infection
    • Johnson, L. L. 1992. A protective role for endogenous tumor necrosis factor in Toxoplasma gondii infection. Infect. Immun. 60:1979.
    • (1992) Infect. Immun. , vol.60 , pp. 1979
    • Johnson, L.L.1
  • 16
    • 0031940206 scopus 로고    scopus 로고
    • Decreased resistance of TNF receptor p55- and p75-deficient mice to chronic toxoplasmosis despite normal activation of inducible nitric oxide synthase in vivo
    • Yap, G. S., T. Scharton-Kersten, H. Charest, and A. Sher. 1998. Decreased resistance of TNF receptor p55- and p75-deficient mice to chronic toxoplasmosis despite normal activation of inducible nitric oxide synthase in vivo. J. Immunol. 160:1340.
    • (1998) J. Immunol. , vol.160 , pp. 1340
    • Yap, G.S.1    Scharton-Kersten, T.2    Charest, H.3    Sher, A.4
  • 17
    • 0032055198 scopus 로고    scopus 로고
    • Crucial role for TNF receptor type 1 (p55), but not TNF receptor type 2 (p75), in murine toxoplasmosis
    • Deckert-Schluter, M., H. Bluethmann, A. Rang, H. Hof, and D. Schluter. 1998. Crucial role for TNF receptor type 1 (p55), but not TNF receptor type 2 (p75), in murine toxoplasmosis. J. Immunol. 160:3427.
    • (1998) J. Immunol. , vol.160 , pp. 3427
    • Deckert-Schluter, M.1    Bluethmann, H.2    Rang, A.3    Hof, H.4    Schluter, D.5
  • 19
    • 1842417179 scopus 로고    scopus 로고
    • Role of interleukin-10 in regulation of T-cell-dependent and T-cell-independent mechanisms of resistance to Toxoplasma gondii
    • Neyer, L. E., G. Grunig, M. Fort, J. S. Remington, D. Rennick, and C. A. Hunter. 1997. Role of interleukin-10 in regulation of T-cell-dependent and T-cell-independent mechanisms of resistance to Toxoplasma gondii. Infect. Immun. 65:1675.
    • (1997) Infect. Immun. , vol.65 , pp. 1675
    • Neyer, L.E.1    Grunig, G.2    Fort, M.3    Remington, J.S.4    Rennick, D.5    Hunter, C.A.6
  • 20
    • 0032036387 scopus 로고    scopus 로고
    • Toxoplasma gondii triggers granulocyte-dependent, cytokine-mediated lethal shock in D-galactosamine sensitized mice
    • Marshall, A. J., and E. Y. Denkers. 1998. Toxoplasma gondii triggers granulocyte-dependent, cytokine-mediated lethal shock in D-galactosamine sensitized mice. Infect. Immun. 66:1325.
    • (1998) Infect. Immun. , vol.66 , pp. 1325
    • Marshall, A.J.1    Denkers, E.Y.2
  • 21
    • 0029847368 scopus 로고    scopus 로고
    • Functional diversity of helper T lymphocytes
    • Abbas, A. K., K. M. Murphy, and A. Sher. 1996. Functional diversity of helper T lymphocytes. Nature 383:787.
    • (1996) Nature , vol.383 , pp. 787
    • Abbas, A.K.1    Murphy, K.M.2    Sher, A.3
  • 22
    • 0023726937 scopus 로고
    • Anti-proliferative effect of IFN-γ in immunoregulation. I. IFN-γ inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clones
    • Gajewski, T. F., and F. W. Fitch. 1988. Anti-proliferative effect of IFN-γ in immunoregulation. I. IFN-γ inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clones. J. Immunol. 140:4245.
    • (1988) J. Immunol. , vol.140 , pp. 4245
    • Gajewski, T.F.1    Fitch, F.W.2
  • 23
    • 0029841124 scopus 로고    scopus 로고
    • + T cell-dependent, IFN-γ-mediated necrosis of the small intestine with genetic susceptibility of mice to peroral infection with Toxoplasma gondii
    • + T cell-dependent, IFN-γ-mediated necrosis of the small intestine with genetic susceptibility of mice to peroral infection with Toxoplasma gondii. J. Exp. Med. 184:597.
    • (1996) J. Exp. Med. , vol.184 , pp. 597
    • Liesenfeld, O.1    Kosek, J.2    Remington, J.S.3    Suzuki, Y.4
  • 24
    • 0025265884 scopus 로고
    • The use of primers from highly conserved pol regions to identify uncharacterized retroviruses by the polymerase chain reaction
    • Donehower, L. A., R. C. Bohannon, R. J. Ford, and R. A. Gibss. 1990. The use of primers from highly conserved pol regions to identify uncharacterized retroviruses by the polymerase chain reaction. J. Virol. Methods 28:33.
    • (1990) J. Virol. Methods , vol.28 , pp. 33
    • Donehower, L.A.1    Bohannon, R.C.2    Ford, R.J.3    Gibss, R.A.4
  • 25
    • 0027264849 scopus 로고
    • IL-12 is required for the T-cell independent induction of IFN-γ by an intracellular parasite and induces resistance in T-cell-deficient hosts
    • Gazzineili, R. T., S. Hieny, T. Wynn, S. Wolf, and A. Sher. 1993. IL-12 is required for the T-cell independent induction of IFN-γ by an intracellular parasite and induces resistance in T-cell-deficient hosts. Proc. Natl. Acad. Sci. USA 90: 6115.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 6115
    • Gazzineili, R.T.1    Hieny, S.2    Wynn, T.3    Wolf, S.4    Sher, A.5
  • 27
    • 0001909501 scopus 로고    scopus 로고
    • Immune regulation in parasitic infection and disease
    • W. E. Paul, ed. Lippincott-Raven. Philadelphia
    • Pearce, E., P. Scott and A. Sher. 1999. Immune regulation in parasitic infection and disease. In Fundamental Immunology. W. E. Paul, ed. Lippincott-Raven. Philadelphia, p. 1271.
    • (1999) Fundamental Immunology , pp. 1271
    • Pearce, E.1    Scott, P.2    Sher, A.3
  • 28
    • 0030970867 scopus 로고    scopus 로고
    • Inducible nitric oxide is essential for host control of persistent but not acute infection with the intracellular pathogen Toxoplasma gondii
    • Scharton-Kersten, T., G. Yap, J. Magram, and A. Sher. 1997. Inducible nitric oxide is essential for host control of persistent but not acute infection with the intracellular pathogen Toxoplasma gondii. J. Exp. Med. 185:1.
    • (1997) J. Exp. Med. , vol.185 , pp. 1
    • Scharton-Kersten, T.1    Yap, G.2    Magram, J.3    Sher, A.4
  • 29
    • 0017593386 scopus 로고
    • Mortality and other parameters of concomitant infections in albino mice: The Schistosoma-Toxoplasma model
    • Kloetzel, K., P. Chieffi, J. Faleiros, and T. Filho. 1977. Mortality and other parameters of concomitant infections in albino mice: the Schistosoma-Toxoplasma model. Trop. Geog. Med. 29:407.
    • (1977) Trop. Geog. Med. , vol.29 , pp. 407
    • Kloetzel, K.1    Chieffi, P.2    Faleiros, J.3    Filho, T.4
  • 30
    • 0028589597 scopus 로고
    • Increased susceptibility of mice infected with Schistosoma mansoni to recombinant vaccinia virus: Association of viral persistence with egg granuloma formation
    • Actor, J. K., M. A. Marshall, I. A. Eltoum, R. M. Buller, J. A. Berzofsky, and A. Sher. 1994. Increased susceptibility of mice infected with Schistosoma mansoni to recombinant vaccinia virus: association of viral persistence with egg granuloma formation. Eur. J. Immunol. 24:3050.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 3050
    • Actor, J.K.1    Marshall, M.A.2    Eltoum, I.A.3    Buller, R.M.4    Berzofsky, J.A.5    Sher, A.6
  • 31
    • 0027388944 scopus 로고
    • Helminth infection results in decreased virus-specific CD8+ cytotoxic T-cell and Th1 cytokine responses as well as delayed virus clearance
    • Actor, J. K., M. Shirai, M. C. Kullberg, R. M. Buller, A. Sher, and J. A. Berzofsky. 1993. Helminth infection results in decreased virus-specific CD8+ cytotoxic T-cell and Th1 cytokine responses as well as delayed virus clearance. Proc. Natl. Acad. Sci. USA 90:948.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 948
    • Actor, J.K.1    Shirai, M.2    Kullberg, M.C.3    Buller, R.M.4    Sher, A.5    Berzofsky, J.A.6
  • 32
    • 0026506715 scopus 로고
    • Infection with Schistosoma mansoni alters Th1/Th2 cytokine responses to a non-parasite antigen
    • Kullberg, M. C., E. J. Pearce, S. A. Hieny, and A. Sher. 1992. Infection with Schistosoma mansoni alters Th1/Th2 cytokine responses to a non-parasite antigen. J. Immunol. 148:3264.
    • (1992) J. Immunol. , vol.148 , pp. 3264
    • Kullberg, M.C.1    Pearce, E.J.2    Hieny, S.A.3    Sher, A.4
  • 33
    • 0030060748 scopus 로고    scopus 로고
    • Impairment of tetanus toxoid-specific Th1-like immune responses in humans infected with Schistosoma mansoni
    • Sabin, E. A., M. I. Araujo, E. M. Carvalho, and E. J. Pearce. 1996. Impairment of tetanus toxoid-specific Th1-like immune responses in humans infected with Schistosoma mansoni. J. Infect. Dis. 173:269.
    • (1996) J. Infect. Dis. , vol.173 , pp. 269
    • Sabin, E.A.1    Araujo, M.I.2    Carvalho, E.M.3    Pearce, E.J.4
  • 34
    • 0030867026 scopus 로고    scopus 로고
    • γ-interferon induces Fas-dependent apoptosis of Peyer's patch T cells in mice following peroral infection with Toxoplasma gondii
    • Liesenfeld, O., J. C. Kosek, and Y. Suzuki. 1997. γ-interferon induces Fas-dependent apoptosis of Peyer's patch T cells in mice following peroral infection with Toxoplasma gondii. Infect. Immun. 65:4682.
    • (1997) Infect. Immun. , vol.65 , pp. 4682
    • Liesenfeld, O.1    Kosek, J.C.2    Suzuki, Y.3
  • 36
    • 0025099723 scopus 로고
    • Tumor necrosis factor (TNF) as a mediator of macrophage helminthotoxic activity
    • James, S., J. Glaven, S. Goldenberg, M. Meltzer, and E. Pearce. 1990. Tumor necrosis factor (TNF) as a mediator of macrophage helminthotoxic activity. Parasite Immunol. 12:1.
    • (1990) Parasite Immunol. , vol.12 , pp. 1
    • James, S.1    Glaven, J.2    Goldenberg, S.3    Meltzer, M.4    Pearce, E.5
  • 38
    • 0027967445 scopus 로고
    • The role of cytokines in formation of the schistosome egg granuloma
    • Boros, D. 1994. The role of cytokines in formation of the schistosome egg granuloma. Immunobiology 191:441.
    • (1994) Immunobiology , vol.191 , pp. 441
    • Boros, D.1
  • 40
    • 0028999453 scopus 로고
    • Tumor necrosis factor-induced hepatocyte apoptosis precedes liver failure in experimental murine shock models
    • Leist, M., F. Gantner, I. Bohlinger, G. Tiegs, P. Germann, and A. Wendel. 1995. Tumor necrosis factor-induced hepatocyte apoptosis precedes liver failure in experimental murine shock models. Am. J. Pathol. 146:1220.
    • (1995) Am. J. Pathol. , vol.146 , pp. 1220
    • Leist, M.1    Gantner, F.2    Bohlinger, I.3    Tiegs, G.4    Germann, P.5    Wendel, A.6
  • 41
    • 0030662226 scopus 로고    scopus 로고
    • Nitric oxide inhibits apoptosis by preventing increases in caspase-3-like activity via two distinct mechanisms
    • Kim, Y., R. Talanian, and T. Billiar. 1997. Nitric oxide inhibits apoptosis by preventing increases in caspase-3-like activity via two distinct mechanisms. J. Biol. Chem. 272:31138.
    • (1997) J. Biol. Chem. , vol.272 , pp. 31138
    • Kim, Y.1    Talanian, R.2    Billiar, T.3
  • 42
    • 0031444279 scopus 로고    scopus 로고
    • A dichotomous role for nitric oxide during acute Toxoplasma gondii infection in mice
    • Khan, I. A., J. D. Schwartzman, T. Matsuura, and L. H. Kasper. 1997. A dichotomous role for nitric oxide during acute Toxoplasma gondii infection in mice. Proc. Natl. Acad. Sci. USA 94:13955.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 13955
    • Khan, I.A.1    Schwartzman, J.D.2    Matsuura, T.3    Kasper, L.H.4
  • 43
    • 0018376287 scopus 로고
    • Schisiosoma mansoni infection in T-cell deprived mice, and the ameliorating effect of administering homologous chronic infection serum. I. Pathogenesis
    • Doenhoff, M. J., R. Musallam, J. Bain, and A. McGregor. 1979. Schisiosoma mansoni infection in T-cell deprived mice, and the ameliorating effect of administering homologous chronic infection serum. I. Pathogenesis. Am. J. Trop. Med. Hyg. 28:260.
    • (1979) Am. J. Trop. Med. Hyg. , vol.28 , pp. 260
    • Doenhoff, M.J.1    Musallam, R.2    Bain, J.3    McGregor, A.4
  • 44
    • 0019346273 scopus 로고    scopus 로고
    • Immunological control of hepatotoxicity and parasite egg excretion in Schistosoma mansoni infections: Stage specificity of the reactivity of immune serum in T-cell deprived mice
    • 19981
    • Doenhoff, M., S. Pearson, D. Dunne, Q. Bickle, and S. Lucas. 19981. Immunological control of hepatotoxicity and parasite egg excretion in Schistosoma mansoni infections: stage specificity of the reactivity of immune serum in T-cell deprived mice. Trans. R. Soc. Trop. Med. Hyg. 75:41.
    • Trans. R. Soc. Trop. Med. Hyg. , vol.75 , pp. 41
    • Doenhoff, M.1    Pearson, S.2    Dunne, D.3    Bickle, Q.4    Lucas, S.5
  • 45
    • 0017762654 scopus 로고
    • Altered schistosome granuloma formation in nude mice
    • Byram, J., and F. Von Lichtenberg. 1977. Altered schistosome granuloma formation in nude mice. Am. J. Trop. Med. Hyg. 26:944.
    • (1977) Am. J. Trop. Med. Hyg. , vol.26 , pp. 944
    • Byram, J.1    Von Lichtenberg, F.2
  • 46
    • 0025744455 scopus 로고
    • The purification, characterization, serological activity and hepatotoxic properties of two cationic glycoproteins from Schistosoma mansoni eggs
    • Dunne, D., F. M. Jones, and M. J. Doenhoff. 1991. The purification, characterization, serological activity and hepatotoxic properties of two cationic glycoproteins from Schistosoma mansoni eggs. Parasitology 103:225.
    • (1991) Parasitology , vol.103 , pp. 225
    • Dunne, D.1    Jones, F.M.2    Doenhoff, M.J.3
  • 47
    • 0017614431 scopus 로고
    • Toxoplasmosis and the host-parasite relationship in murine schistosomiasis mansoni
    • Mahmoud, A., G. Strickland, and K. Warren. 1977. Toxoplasmosis and the host-parasite relationship in murine schistosomiasis mansoni. J. Infect. Dis. 135:408.
    • (1977) J. Infect. Dis. , vol.135 , pp. 408
    • Mahmoud, A.1    Strickland, G.2    Warren, K.3
  • 48
    • 0029166483 scopus 로고
    • Cytokine regulation of granuloma formation in schistosomiasis
    • Wynn, T. A., and A. W. Cheever. 1995. Cytokine regulation of granuloma formation in schistosomiasis. Curr. Opin. Immunol. 7:505.
    • (1995) Curr. Opin. Immunol. , vol.7 , pp. 505
    • Wynn, T.A.1    Cheever, A.W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.