Thrombocytopenia and thromboembolism in pediatric systemic lupus erythematosus

Journal of Pediatrics

Volumn 143, Issue 5, 2003, Pages 666-669

  Schmugge, Markus ^b   Revel Vilk, Shoshana ^b   Hiraki, Linda ^b   Rand, Margaret L ^b   Blanchette, Victor S ^b   Silverman, Earl D ^a  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CARDIOLIPIN ANTIBODY; LUPUS ANTICOAGULANT;

ADOLESCENT; ARTICLE; CHILD; CHILDHOOD DISEASE; CLINICAL FEATURE; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; DISEASE SEVERITY; EPIDEMIOLOGICAL DATA; HUMAN; INCIDENCE; LABORATORY TEST; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; RETROSPECTIVE STUDY; RISK FACTOR; SPLENECTOMY; SYSTEMIC LUPUS ERYTHEMATOSUS; THROMBOCYTOPENIA; THROMBOCYTOPENIC PURPURA; THROMBOEMBOLISM;

EID: 0344011090     PISSN: 00223476     EISSN: None     Source Type: Journal    
DOI: 10.1067/S0022-3476(03)00389-5     Document Type: Article

References (15)

1. Tan EM, Cohen AS, Fries J. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1983;25:1271-7.
2. Nossent JC, Swaak AJ. Prevalence and significance of haematological abnormalities in patients with systemic lupus erythematosus. Q J Med 1991;291:605-12.
3. Cervera R, Khamashta MA, Font J, Sebastiani GD, Gil A, Lavilla P, et al. Morbidity and mortality in systemic lupus erythematosus during a 5-year period: a multicenter prospective study of 1,000 patients. European Working Party on Systemic Lupus Erythematosus. Medicine 1999;78: 167-75.
4. Mok CC, Lee KW, Ho CTK, Lau CS, Wong RWS. A prospective study of survival and prognostic indicators of systemic lupus erythematosus in a southern Chinese population. Rheumatology 2000;39:399-406.
5. Berube C, Mitchell L, Silverman E, David M, Saint Cyr C, Laxer R, et al. The relationship of antiphospholipid antibodies to thromboembolic events in pediatric patients with systemic lupus erythematodes: a cross-sectional study. Pediatr Res 1998;44:351-6.
6. George JN, Woolf SH, Raskob GE, Wasser JS, Aledort LM, Ballem JP, et al. Idiopathic thrombocytopenia purpura: a practice guideline developed by explicit methods for the American Society of Hematology. Blood 1996;88: 3-40.
7. Brunner HI, Freedman M, Silverman ED. Close relationship between systemic lupus erythematosus and thrombotic thrombocytopenic purpura in childhood. Arthritis Rheum 1999;42:2346-55.
8. Tucker LB, Menon S, Schaller JG, Isenberg DA. Adult- and childhood-onset systemic lupus erythematosus: a comparison of onset, clinical features, serology, and outcome. Rheumatology 1995;34:866-72.
9. Alger M, Alarcon-Segovia D, Rivero SJ. Hemolytic anemia and thrombocytopenic purpura: two related subsets of systemic lupus erythematosus. J Rheumatol 1977;4:351-7.
10. Blanchette V, Carcao M. Approach to the investigation and management of immune thrombocytopenic purpura in children. Semin Hematol 2000;37:299-314.
11. Zimmermann SA, Ware RE. Clinical significance of the antinuclear antibody test in selected children with idiopathic thrombocytopenic purpura. J Pediatr Hematol Oncol 1997;19:297-303.
12. Galindo M, Khamashta MA, Hughes GR. Splenectomy for refractory thrombocytopenia in the antiphospholipid syndrome. Rheumatology 1999; 38:848-53.
13. Alarcon-Segovia, D. Splenectomy has a limited role in the management of lupus with thrombocytopenia. J Rheumatol 2002;29:1-2.
14. Arnal C, Piette JC, Leone J, Taillan B, Hachulla E, Roudot-Thoraval F, et al. Treatment of severe immune thrombocytopenia associated with systemic lupus erythematosus. J Rheumatol 2002;29:75-83.
15. Nojima J, Suehisa E, Kuratsune H, Machii T, Koike T, Kitani T, et al. Platelet activation induced by combined effects of anticardiolipin and lupus anticoagulant IgG antibodies in patients with systemic lupus erythematosus - possible association with thrombotic and thrombocytopenic complications. Thromb Haemost 1999;81:436-41.