Clinical significance of the antinuclear antibody test in selected children with idiopathic thrombocytopenic purpura

American Journal of Pediatric Hematology/Oncology

Volumn 19, Issue 4, 1997, Pages 297-303

  Zimmerman, Sherri A ^a   Ware, Russell E ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Antinuclear antibody; Chronic ITP; Idiopathic thrombocytopenic purpura; Systemic lupus erythematosus

Indexed keywords

ANTINUCLEAR ANTIBODY; AUTOANTIBODY; CARDIOLIPIN ANTIBODY; DOUBLE STRANDED DNA; RIBONUCLEOPROTEIN ANTIBODY;

ADOLESCENT; ARTICLE; AUTOIMMUNITY; CHILD; FEMALE; FOLLOW UP; HUMAN; IDIOPATHIC THROMBOCYTOPENIC PURPURA; IMMUNOASSAY; INTERVIEW; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SYSTEMIC LUPUS ERYTHEMATOSUS;

ADOLESCENT; ANTIBODIES, ANTINUCLEAR; CHILD; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; PREDICTIVE VALUE OF TESTS; PURPURA, THROMBOCYTOPENIC, IDIOPATHIC; RETROSPECTIVE STUDIES;

EID: 0030687514     PISSN: 01928562     EISSN: None     Source Type: Journal    
DOI: 10.1097/00043426-199707000-00006     Document Type: Article

References (24)

1. Ware R, Kinney TR. Immunopathology of childhood idiopathic thrombocytopenic purpura. CRC Crit Rev Oncol/Hematol 1987; 7: 169-81.
2. Karpatkin S. Autoimmune thrombocytopenic purpura. Semin Hematol 1985; 22: 260-88.
3. Ware R, Kinney TR. Therapeutic considerations in childhood idiopathic thrombocytopenic purpura. CRC Crit Rev Oncol/Hematol 1987; 7: 139-52.
4. George JN, Woolf SH, Raskob GE, et al. Idiopathic thrombocytopenic purpura: a practice guideline developed by explicit methods for the American Society of Hematology. Blood 1996; 88: 3-40.
5. Chudwin DS, Ammann AJ, Cowan MJ, et al. Significance of a positive antinuclear antibody test in a pediatric population. Am J Dis Child 1983; 137: 1103-6.
6. Lang BA, Silverman ED. A clinical overview of systemic lupus erythematosus in childhood. Pediatr Rev 1993; 14: 194-201.
7. Nakamura RM, Bylund DJ. Contemporary concepts for the clinical and laboratory evaluation of systemic lupus erythematosus and " lupus-like” syndrome. J Clin Lab Anal 1994; 8: 347-59.
8. Deane PMG, Liard G, Siegel DM, et al. The outcome of children referred to a pediatric rheumatology clinic with a positive antinuclear antibody test but without an autoimmune disease. Pediatrics 1995; 95: 892-5.
9. Singsen BH, Bernstein BH, Kornreich HK, et al. Mixed connective tissue disease in childhood. A clinical and serologic survey. J Pediatr 1977; 90: 893-900.
10. Osborn TG, Patel NJ, Moore TL, et al. Use of the HEp-2 cell substrate in the detection of antinuclear antibodies in juvenile rheumatoid arthritis. Arthritis Rheum 1984; 27: 1286-9.
11. Arroyave CM, Giambrone MJ, Rich KC, et al. The frequency of antinuclear antibody (ANA) in children by use of mouse kidney (MK) and human epithelial cells (HEp-2) as substrates. J Allergy Clin Immunol 1988; 82: 741-4.
12. Allen RC, Dewez P, Stuart L, et al. Antinuclear antibodies using HEp-2 cells in normal children and in children with common infections. J Paediatr Child Health 1991; 27: 39-42.
13. Cabral DA, Petty RE, Fung M, et al. Persistent antinuclear antibodies in children without identifiable inflammatory rheumatic or autoimmune disease. Pediatrics 1992; 89: 441-4.
14. Rosse WF, Devine DV, Ware R. Reactions of IgG-binding ligands with platelets and platelet-associated IgG. J Clin Invest 1984; 73: 489-96.
15. Tan EM, Cohen AS, Fries JS, et al. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1982; 25: 1271-7.
16. Rabinowitz Y, Dameshek W. Systemic lupus erythematosus after " idiopathic” thrombocytopenic purpura: A Review. A study of systemic lupus erythematosus occurring after 78 splenectomies for " idiopathic” thrombocytopenic purpura, with a review of the pertinent literature. Ann Intern Med 1960; 52: 1-15.
17. Breckenridge RT, Moore RD, Ratnoff OD. A study of thrombocytopenia. New histologic criteria for the differentiation of idiopathic thrombocytopenia and thrombocytopenia associated with disseminated lupus erythematosus. Blood 1967; 30: 39-53.
18. Karpatkin S, Strick N, Karpatkin MB, et al. Cumulative experience in the detection of antiplatelet antibody in 234 patients with idiopathic thrombocytopenic purpura, systemic lupus erythematosus and other clinical disorders. Am J Med 1972; 52: 776-85.
19. Budman DR, Steinberg AD. Hematologic aspects of systemic lupus erythematosus. Ann Intern Med 1977; 86: 220-9.
20. Anderson MJ, Peebles CL, McMillan R, et al. Fluorescent antinuclear antibodies and anti-SS-A/Ro in patients with immune thrombocytopenia subsequently developing systemic lupus erythematosus. Ann Intern Med 1985; 103: 548-50.
21. Perez HD, Katler E, Embury S. Idiopathic thrombocytopenic purpura with high-titer, speckled pattern antinuclear antibodies: possible marker for systemic lupus erythematosus. Arthritis Rheum 1985; 28: 596-7.
22. Panzer S, Penner E, Graninger W, et al. Antinuclear antibodies in patients with chronic idiopathic autoimmune thrombocytopenia followed 2-30 years. Am J Hematol 1989; 32: 100-3.
23. Miescher PA, Tucci A, Beris P, et al. Autoimmune hemolytic anemia and/or thrombocytopenia associated with lupus parameters. Semin Hematol 1992; 29: 13-17.
24. Kurata Y, Miyagawa S, Kosugi S, et al. High-titer antinuclear antibodies, Anti-SSA/Ro antibodies and anti-nuclear RNP antibodies in patients with idiopathic thrombocytopenic purpura. Thromb Haemost 1994; 71: 184-7.