Helicobacter pylori induces DNA damage in vitro

Cancer Letters

Volumn 152, Issue 2, 2000, Pages 145-149

  Schmaußer, Bernd ^a   Mueller, Stefan O ^b   Eck, Matthias ^a   Möller, Marianne ^b   Müller Hermelink, Hans Konrad ^a   Stopper, Helga ^b  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

DNA damage; Gastric carcinoma; Genotoxicity; Helicobacter pylori; L5178Y mouse lymphoma cells; Micronuclei

Indexed keywords

ANIMAL CELL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; ESCHERICHIA COLI; GENOTOXICITY; HELICOBACTER PYLORI; IN VITRO STUDY; LYMPHOMA CELL LINE; MICRONUCLEUS TEST; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CELL SURVIVAL; DNA DAMAGE; ESCHERICHIA COLI; HELICOBACTER PYLORI; MICE; MICRONUCLEUS TESTS;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; HELICOBACTER PYLORI;

EID: 0343963018     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(99)00442-5     Document Type: Article

References (16)

1. Parsonnet J., Friedmann G.D., Vandersteen D.P., Chang Y., Vogelman J.H., Orentreich N., Sibley R.K. Helicobacter pylori infection and the risk of gastric carcinoma. N. Engl. J. Med. 325:1991;1127-1131.
2. Foreman D. Eurogast Study Group, An international association between Helicobacter pylori infection and gastric cancer. Lancet. 3421:1993;359-362.
3. IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Helicobacter pylori. In: Schistosomes, Liver Flukes, and Helicobacter pylori: Views and Expert Opinions of an IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, IARC, Lyon, 1994, pp.177-240.
4. Watanabe T., Tada M., Nagai H., Sasaki S., Nakao M. Helicobacter pylori infection induces gastric cancer in Mongolian gerbils. Gastroenterology. 115:1998;642-648.
5. Anti M., Armuzzi A., Gasbarrini A., Gasbarrini G. Importance of changes in epithelial cell turnover during Helicobacter pylori infection in gastric carcinogenesis. Gut. 43:1998;27-32.
6. Zhang Z.W., Patchett S.E., Perrett D., Katelaris P.H., Domizio P., Farthing M.J.G. The relation between gastric vitamin C concentrations, mucosal histology, and CagA seropositivity in the human stomach. Gut. 43:1998;322-326.
7. Hahm K.B., Lee K.J., Kim J.H., Cho S.W., Chung M.H. Helicobacter pylori infection, oxidative DNA damage, gastric carcinogenesis, and reversibility by rebamipide. Dig. Dis. 43:1998;72-77.
8. Miller B., Locher F., Seelbach A., Stopper H., Utesch D., Madle S. Evaluation of the in vitro micronucleus test (MNT) as an alternative to the in vitro chromosomal aberration assay: position of the GUM working group "in vitro MNT" Mutat. Res. 410:1998;81-116.
9. Stopper H., Müller S.O. Micronuclei: biological endpoint for genotoxicity. Toxicol. In Vitro. 11:1997;661-667.
10. Combes R.D., Stopper H., Caspary W.J. The use of the L5178Y mouse lymphoma cells to assess mutagenic, clastogenic and aneugenic activity of chemicals. Mutagenesis. 10:(5):1995;403-408.
11. Ning T., Ma H., Zhou J. Micronucleus effect induced by Helicobacter pylori on human gastric mucous epithelial membrane. Chung Hua Yu Fang I Hsueh Tsa Chih. 30:(3):1996;139-140.
12. Fenech M. The cytokinesis-block micronucleus technique: a detailed description of the method and its application to genotoxicity studies in human populations. Mutat. Res. 285:1993;35-44.
13. J.M. Parry, A proposal for a new OECD guideline for the in vitro micronucleus test, Eur. J. Genet. Toxicol. 6 (1998) http://www.swan.ac.uk/cget/jounal/ejgt15.htm.
14. Wotherspoon A.C., Ortiz-Hidalgo C., Falzon M.R., Isaacson P.G. Helicobacter pylori- associated gastritis and primary B-cell gastric lymphoma. Lancet. 338:1991;1175-1176.
15. Eck M., Schmaußer B., Haas R., Greiner A., Czub S., Müller-Hermelink H.K. MALT-type lymphoma of the stomach is associated with Helicobacter pylori strains expressing the CagA protein. Gastroenterology. 112:(5):1997;1482-1486.
16. Barrett J.C. Cellular and molecular mechanisms of asbestos carcinogenicity: implications for biopersistence. Environ. Health Perspect. 102:(Suppl. 5):1994;19-23.