The relation between gastric vitamin C concentrations, mucosal histology, and CagA seropositivity in the human stomach

Gut

Volumn 43, Issue 3, 1998, Pages 322-326

  Zhang, Z W ^a   Patchett, S E ^a   Perrett, D ^a   Katelaris, P H ^a   Domizio, P ^a   Farthing, M J G ^a  

^a ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

Author keywords

Ascorbic acid; Gastric juice; Gastric mucosa; Helicobacter pylori; Premalignancy

Indexed keywords

ASCORBIC ACID; DEHYDROASCORBIC ACID;

ADULT; AGED; ANTIBODY DETECTION; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; HELICOBACTER PYLORI; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; PRECANCER; PRIORITY JOURNAL; SEROLOGY; STOMACH BIOPSY; STOMACH CANCER; STOMACH JUICE; STOMACH MUCOSA; VITAMIN METABOLISM;

EID: 0031719810     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.43.3.322     Document Type: Article

References (34)

1. Block G. Vitamin C and cancer prevention: the epidemiologic evidence. Am J Clin Nutr 1991;53:270S-82S.
2. Correa P, Fontham E, Pickle LW, et al. Dietary determinants of gastric cancer in south Louisiana inhabitants. J Natl Cancer Inst 1985;75:645-54.
3. Kyrtopoulos SA. N-nitroso compound formation in human gastric juice. Cancer Surv 1989;8:423-42.
4. Mirvish SS, Wallcave L, Eagen M, et al. Ascorbate-nitrite reaction: possible means of blocking the formation of carcinogenic N-nitroso compounds. Science 1972;177:65-8.
5. Lewin S. Structures and characteristic properties of the ascorbic system. In: Lewin S, ed. Vitamin C: its molecular biology and medical potential. London: Academic Press, 1976;5-39.
6. Poydock ME, Harguindey S, Hart T, et al. Mitogenic inhibition and effect on survival of mice bearing L1210 leukemia using a combination of dehydroascorbic acid and hydroxycobalamin. Am J Clin Oncol 1985;8:266-9.
7. Poydock ME, Reikert D, Rice J, et al. Inhibiting effect of dehydroascorbic acid on cell division in ascites tumors in mice. Exp Cell Biol 1982;50:34-8.
8. Edgar JA. Dehydroascorbic acid and cell division. Nature 1970;227:24-6.
9. O'Connor HJ, Schorah CJ, Habibzedah N, et al. Vitamm C in the human stomach: relation to gastric pH, gastroduodenal disease, and possible sources. Gut 1989;30:436-42.
10. Rathbone BJ, Johnson AW, Wyatt JI, et al. Ascorbic acid: a factor concentrated in human gastric juice. Clin Sci 1989;76:237-41.
11. Sobala GM, Crabtree JE, Dixon MF, et al. Acute Helicobacter pylori infection: clinical features, local and systemic immune response, gastric mucosal histology, and gastric juice ascorbic acid concentrations. Gut 1991;32: 1415-8.
12. Parsonnet J, Friedman GD, Vandersteen DP, et al. Helicobacter pylori infection and the risk of gastric carcinoma. N Engl J Med 1991;325:1127-31.
13. Nomura A, Stemmermann GN, Chyou PH, et al. Helicobacter pylori infection and gastric carcinoma among Japanese Americans in Hawaii. N Engl J Med 1991;325:1132-6.
14. The EUROGAST Study Group. An international association between Helicobacter pylori infection and gastric cancer. Lancet 1993;341:1359-62.
15. Sobala GM, Schorah CJ, Shires S, et al. Effect of eradication of Helicobacter pylori on gastric juice ascorbic acid concentrations. Gut 1993;34:1038-41.
16. Rokkas T, Papatheodorou G, Karameris A, et al. Helicobacter pylori infection and gastric juice vitamin C levels. Impact of eradication. Dig Dis Sci 1995;40:615-21.
17. Rood JC, Ruix B, Fontham ETH, et al. Helicobacter pylori-associated gastritis and the ascorbic acid concentration in gastric juice. Nutr Cancer 1994;22:65-72.
18. Banerjee S, Hawksby C, Miller S, et al. Effect of Helicobacter pylori and its eradication on gastric juice ascorbic acid. Gut 1994;35:317-22.
19. Blaser MJ, Perez-Perez GI, Kleanthous H, et al. Infection with Helicobacter pylori strains possessing cagA is associated with an increased risk of developing adenocarcinoma of the stomach. Cancer Res 1995;55:2111-15.
20. Crabtree JE, Covacci A, Farmery SM, et al. Helicobacter pylori induced interleukin-8 expression in gastric epithelial cells is associated with CagA positive phenotype. J Clin Pathol 1995;48:41-5.
21. Crabtree JE, Farmery SM, Lindley IJD, et al. CagA cytotoxic strains of Helicobacter pylori and interleukin-8 in gastric epithelial-cell lines. J Clin Pathol 1994;47:945-50.
22. Peek RM, Miller GG, Tham KT, et al. Detection of cagA expression in vitro and demonstration of preferential cytokine expression by cagA H. pylori strains in gastric mucosa. Am J Gastroenterol 1994;89:1344.
23. Tanaka K, Wilks M, Coates PJ, et al. Mycobacterium paratuberculosis and Crohn's disease. Gut 1991;32:43-5.
24. Price AB. The Sydney System: histological division. J Gastroenterol Hepatol 1991;6:209-22.
25. Sobala GM, Schorah CJ, Sanderson M, et al. Ascorbic acid in the human stomach. Gastroenterology 1989;97:357-63.
26. Sobala GM, Pignatelli B, Schorah CJ, et al. Levels of nitrite, nitrate, N-nitroso compounds, ascorbic acid and total bile acids in gastric juice of patients with and without precancerous conditions of the stomach. Carcinogenesis 1991;12:193-8.
27. Cuzick J. A Wilcoxon-type test for trend. Stat Med 1985;4:87-90.
28. Schorah CJ, Sobala GM, Sanderson M, et al. Gastric juice ascorbic acid; effects of disease and implications for gastric carcinogenesis. Am J Clin Nutr 1991;53:287S-93S.
29. Odum L, Andersen LP. Investigation of Helicobacter pylori ascorbic acid oxidating activity. FEMS Immunol Med Microbiol 1995;10:289-94.
30. Hansson LE, Nyren O, Hsing AW, et al. The risk of stomach cancer in patients with gastric or duodenal ulcer disease. N Engl J Med 1996;335:242-9.
31. Poydock ME. Effect of combined ascorbic acid and B-12 on survival of mice with implanted Ehrlich carcinoma and L1210 leukemia. Am J Clin Nutr 1991;54:1261S-5S.
32. Yamafuji K, Nakamura Y, Omura H, et al. Antitumor potency of ascorbic, dehydroascorbic or 2,3-diketogulonic acid and their action on deoxyribonucleic acid. Zeitschrift fur Krebsforschung 1971;76:1-7.
33. Crabtree JE, Taylor JD, Wyatt JI, et al. Mucosal IgA recognition of Helicobacter pylori 120 kDa protein, peptic ulceration, and gastric pathology. Lancet 1991;338:332-5.
34. Lewin S. Biological activity and potential. In: Lewin S, ed. Vitamin C: its molecular biology and medical potential. London: Academic Press, 1976;75-103.