Molecular rigidity and potency of bispyridinium type allosteric modulators at muscarinic M2-receptors

Life Sciences

Volumn 60, Issue 22, 1997, Pages 1995-2003

  Tränkle, Christian ^a   Elis, Kirsten ^a   Wiese, Michael ^b   Mohr, Klaus ^a  

^a UNIVERSITY OF BONN   (Germany)

^b MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

allosteric modulation; bispyridinium compounds; M2 receptor; molecular modelling; porcine; structure activity relationships

Indexed keywords

ALCURONIUM; BIS(PYRIDINIUM OXIME) DERIVATIVE; GALLAMINE; METHYLSCOPOLAMINE; MUSCARINIC M2 RECEPTOR;

ALLOSTERISM; ANIMAL CELL; BINDING AFFINITY; CONTROLLED STUDY; DRUG POTENCY; DRUG RECEPTOR BINDING; GUINEA PIG; HEART MUSCLE FIBER MEMBRANE; NONHUMAN; REVIEW; STRUCTURE ACTIVITY RELATION;

ANIMALIA; CAVIA PORCELLUS; SUIDAE; SUS SCROFA;

EID: 0343924207     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(97)00164-1     Document Type: Article

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