Behavioral effects mediated by the modulatory glycine site of the NMDA receptor in the anterodorsal striatum and nucleus accumbens

Journal of Neuroscience

Volumn 16, Issue 4, 1996, Pages 1561-1569

  Kretschmer, Beate D ^a   Schmidt, Werner J ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

7 chlorokynurenate; D serine; glycine; locomotion; NMDA; nucleus accumbens; stereotypy; striatum

Indexed keywords

7 CHLOROKYNURENIC ACID; 8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; GLYCINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; CATALEPSY; CORPUS STRIATUM; LOCOMOTION; MALE; NEUROTRANSMISSION; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; RAT; RECEPTOR DENSITY; STEREOTYPY; TISSUE DISTRIBUTION;

EID: 0029966645     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.16-04-01561.1996     Document Type: Article

References (60)

1. Albin RL, Makowiec RL, Hollingsworth ZR, Dure IV LS, Penny JB, Young AB (1992) Excitatory amino acid binding sites in the basal ganglia of the rat: quantitative autoradiographic study. Neuroscience 46:35-48.
2. Alexander GE, Crutcher MD (1990) Functional architecture of basal ganglia circuits: neural substrates of parallel processing. Trends Neurosci 13:266-271.
3. Alexander GE, DeLong MR, Strick PL (1986) Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Annu Rev Neurosci 9:357-381.
4. Berendse HW, Groenewegen HJ, Lohman AM (1992) Compartmental distribution of ventral striatal neurons projecting to the mesencephalon in the rat. J Neurosci 12:2079-2103.
5. Bigge CF (1993) Structural requirements for the development of potent N-methyl-D-aspartic acid (NMDA) receptor antagonists. Biochem Pharmacol 45:1547-1561.
6. Bristow U, Hutson PH, Thorn L, Tricklebank MD (1993) The glycine/ NMDA receptor antagonist, R-(+)-HA-966, blocks activation of the mesolimbic dopamine system induced by phencyclidine and dizocilpine (MK-801) in rodents. Br J Pharmacol 108:1156-1163.
7. Calderon SF, Sanberg PR, Norman AB (1988) Quinolinic acid lesions of rat striatum abolish D1- and D2- dopamine receptor-mediated catalepsy. Brain Res 450:403-407.
8. Creese I, Iversen SD (1975) The pharmacological and anatomical substrates of amphetamine response in the rat. Brain Res 83:419-436.
9. Donzanti BA, Uretsky NJ (1984) Antagonism of the hypermotility response induced by excitatory amino acids in the rat nucleus accumbens. Naunyn-Schmiedebergs Arch Pharmacol 325:1-7.
10. Ellenbroek B, Schwarz M, Sontag K-H, Jaspers R, Cools A (1985) Muscular rigidity and delineation of a dopamine-specific neostriatal subregion: tonic EMG activity in rats. Brain Res 345:132-140.
11. Gerfen CR, Engber TM, Mahan LC, Sussel Z, Chase TN, Monsma FJ, Sibley DR (1990) D1 and D2 dopamine receptor-regulated gene expression of striatonigral and striatopallidal neurons. Science 250:1429-1432.
12. Graybiel AM (1984) Neurochemically specified subsystems in the basal ganglia. In: Functions of the basal ganglia, Ciba Foundation Symposium 107, pp 114-149. London: Pitman.
13. Haber SN, Lynd-Balta E, Mitchell SJ (1993) The organization of the descending ventral pallidal projections in the monkey. J Comp Neurol 329:111-128.
14. Harrison MB, Wiley RG, Wooten GF (1992) Changes in D2 but not D1 receptor binding in the striatum following a selective lesion of striatopallidal neurons. Brain Res 590:305-310.
15. Hauber W, Schmidt WJ (1993) Discrete quinolinic acid lesions of the lateral but not of the medial caudate-putamen reversed haloperidol-induced catalepsy in rats. J Neural Transm 94:103-114.
16. Hutson PH, Bristow LJ, Thorn L, Tricklebank MD (1991) R-(+)-HA-966, a glycine/NMDA receptor antagonist, selectively blocks the activation of the mesolimbic dopamine system by amphetamine. Br J Pharmacol 103:2037-2044.
17. Imperato A, Scrocco MG, Bacchi S, Angelucci L (1990) NMDA receptors and in vivo dopamine release in the nucleus accumbens and caudatus. Eur J Pharmacol 187:555-556.
18. Iversen SD, Wilkinson S, Simpson B (1971) Enhanced amphetamine responses after frontal cortex lesions in the rat. Eur J Pharmacol 13:387-390.
19. Kelley AE, Throne LC (1992) NMDA receptors mediate the behavioral effects of amphetamine infused into the nucleus accumbens. Brain Res Bull 29:247-254.
20. Kelly PH, Seviour PW, Iversen SD (1975) Amphetamine and apomorphine responses in the rat following 6-OHDA lesions of the nucleus accumbens septi and corpus striatum. Brain Res 94:507-522.
21. Klockgether T, Turski L (1993) Toward an understanding of the role of glutamate in experimental Parkinsonism: agonist-sensitive sites in the basal ganglia. Ann Neurol 34:585-593.
22. Koek W, Colpaert FC (1990) Selective blockade of N-methyl-D-aspartate (NMDA)-induced convulsions by NMDA antagonists and putative glycine antagonists: relationship with phencyclidine-like behavioral effects. J Pharmacol Exp Ther 252:349-357.
23. Kretschmer BD (1994) Felbamate, an anti-convulsive drug, has anti-parkinsonian potential in rats. Neurosci Lett 179:115-118.
24. Kretschmer BD, Zadow B, Volz TL, Volz L, Schmidt WJ (1992) The contribution of the different binding sites of the N-methyl-D-aspartate (NMDA) receptor to the expression of behavior. J Neural Transm 87:23-35.
25. Kretschmer BD, Winterscheid B, Danysz W, Schmidt WJ (1994) Glycine site antagonists abolish dopamine D2 but not D1 receptor mediated catalepsy in rats. J Neural Transm 95:123-136.
26. Kretschmer BD, Bubser M, Schmidt WJ (1995) Behavioral and neurochemical actions of the strychnine-insensitive glycine receptor antagonist, 7-chlorokynurenate, in rats. Eur J Pharmacol 280:37-45.
27. LeMoal M, Simon H (1991) Mesocorticolimbic dopaminergic network: functional and regulatory roles. Physiol Rev 71:155-234.
28. Lynd-Balta E, Haber SN (1994) Primate striatonigral projections: a comparison of the sensorimotor-related striatum and the ventral striatum. J Comp Neurol 345:562-578.
29. McCullough LD, Salamone JD (1992) Increase in extracellular dopamine levels and locomotor activity after direct infusion of phencyclidine into the nucleus accumbens. Brain Res 577:1-9.
30. Meyer MM (1993) Effects of intraaccumbens dopamine agonist SK&F38393 and antagonist SCH23390 on locomotor activities in rats. Pharmacol Biochem Behav 45:843-847.
31. O'Neill KA, Carelli RM, Jarvis MF, Liebman JM (1989) Hyperactivity induced by N-methyl-D-aspartate injections into nucleus accumbens: lack of evidence for mediation by dopaminergic neurons. Pharmacol Biochem Behav 34:739-745.
32. Ossowska K, Karcz M, Wardas J, Wolfarth S (1990) Striatal and nucleus accumbens D1/D2 dopamine receptors in neuroleptic catalepsy. Eur J Pharmacol 182:327-334.
33. Paxinos G, Watson C (1986) The rat brain in stereotaxic coordinates. Sydney: Academic.
34. Pellegrino LJ, Pellegrino AS, Cushman AJ (1986) A stereotaxic atlas of the rat brain. New York: Plenum.
35. Pennartz CMA, Groenewegen HJ, Lopes da Silva FH (1994) The nucleus accumbens as a complex of functionally distinct neuronal ensembles: an integration of behavioural, electrophysiological and anatomical data. Prog Neurobiol 42:719-761.
36. Pierce RC, Rebec GV (1993) Intraneostriatal administration of glutamate antagonists increases behavioral activation and decreases neostriatal ascorbate via nondopaminergic mechanisms. J Neurosci 13:4272-4280.
37. Raffa RB, Ortegon ME, Robisch DM, Martin GE (1989) In vivo demonstration of the enhancement of MK-801 by L-glutamate. Life Sci 44:1593-1599.
38. Ricardo JA (1980) Efferent connections of the subthalamic region in the rat. I. The subthalamic nucleus of luys. Brain Res 202:257-271.
39. Robertson GS, Vincent SR, Fibiger HC (1992) D1 and D2 dopamine receptors differentially regulate c-fos expression in striatonigral and striatopallidal neurons. Neuroscience 49:285-296.
40. 3H]MK-801 binding in rat brain. J Neurochem 60:1344-1353.
41. Scatton B, Worms P, Lloyd KG, Bartholini G (1982) Cortical modulation of striatal function. Brain Res 232:331-343.
42. Schmidt WJ (1986) Intrastriatal injection of DL-2-amino-5-phosphonovaleric acid (AP-5) induces sniffing stereotypy that is antagonized by haloperidol and clozapine. Psychopharmacology 90:123-130.
43. Schmidt WJ, Bubser M (1989) Anticataleptic effects of the N-methyl-D-aspartate antagonist MK-801 in rats. Pharmacol Biochem Behav 32:621-623.
44. Schmidt WJ, Bury D (1988) Behavioural effects of N-methyl-D-aspartate in the anterodorsal striatum in the rat. Life Sci 43:545-549.
45. Schmidt WJ, Zadow B, Kretschmer BD, Hauber W (1991) Anticataleptic potencies of glutamate-antagonists. Amino Acids 1:225-237.
46. Schmidt WJ, Bury D, Geltz U (1992) Dopamine-glutamate interactions in the basal ganglia. In: Dopamin '92 - from neurobiology to neuropathology, p 90.
47. Seeburg PH (1993) The Trends Neurosci/TiPS lecture - the molecular biology of mammalian glutamate receptor channels. Trends Neurosci 16:359-365.
48. Somogyi P, Bolam JP, Totterdell S, Smith AD (1981) Monosynaptic input from the nucleus accumbens-ventral striatum region to retrogradely labelled nigrostriatal neurones. Brain Res 217:245-263.
49. Staton DM, Solomon PR (1984) Microinjection of D-amphetamine into the nucleus accumbens and caudatus putamen differentially affect stereotypy and locomotion in the rat. Physiol Psychol 12:159-162.
50. Surmeier DJ, Eberwine J, Wilson CJ, Cao A, Stefani A, Kitai ST (1992) Dopamine receptor subtypes colocalize in rat striatonigral neurons. Proc Natl Acad Sci USA 89:10178-10182.
51. Svensson L, Zhang J, Johannessen K, Engel JA (1994) Effect of local infusion of glutamate analogue into the nucleus accumbens of rats: an electrochemical and behavioral study. Brain Res 643:155-161.
52. Swerdlow NR, Koob GF (1987) Lesions of the dorsomedial nucleus of the thalamus, medial prefrontal cortex and pedunculopontine nucleus: effects on locomotor activity mediated by nucleus accumbens-ventral pallidal circuitry. Brain Res 412:233-243.
53. Verma A, Kulkarni SK (1992) D1/D2 dopamine and N-methyl-D-aspartate (NMDA) receptor participation in experimental catalepsy in rats. Psychopharmacology 109:477-483.
54. Wedzony K, Golembiowska K, Maj J (1991) A search for the effects of NMDA on the release of dopamine from the rat nucleus caudatus. In: Monitoring molecules in neuroscience (Rollema H, Westerink BHC, Drijhout WJ, eds), pp 321-324. Groningen: University Centre for Pharmacy.
55. Weissenborn R, Winn P (1992) Regulatory behaviour, exploration and locomotion following NMDA or 6-OHDA lesions in the rat nucleus accumbens. Behav Brain Res 51:127-137.
56. Wroblewski JT, Danysz W (1989) Modulation of glutamate receptor - molecular mechanism and functional implications. Annu Rev Pharmacol Toxicol 29:441-474.
57. Yoshida Y, Ono T, Kizu A, Fukushima R, Miyagishi T (1991) Striatal N-methyl-D-aspartate receptors in haloperidol-induced catalepsy. Eur J Pharmacol 203:173-180.
58. Yoshida Y, Ono T, Kawano K, Miyagishi T (1994) Distinct sites of dopaminergic and glutamatergic regulation of haloperidol-induced catalepsy within the rat caudate-putamen. Brain Res 639:139-148.
59. Zadow B, Schmidt WJ (1994a) Lesions of the entopeduncular nucleus and the subthalamic nucleus reduce dopamine antagonist-induced catalepsy in rat. Behav Brain Res 62:71-79.
60. Zadow B, Schmidt WJ (1994b) Role of the basal ganglia output nuclei in the mediation of catalepsy revealed by lesion studies with quinolinic acid in the rat. Behav Pharmacol 5:116.