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Volumn 24, Issue 1, 1999, Pages 1-8

The 21-aminosteroid U-74389F attenuates hyperexpression of GAP-43 and NADPH-diaphorase in the spinal cord of wobbler mouse, a model for amyotrophic lateral sclerosis

Author keywords

21 aminosteroids; GAP 43; NADPH diaphorase; Neurogeneration; Wobbler mouse

Indexed keywords

21 [4 [2,6 BIS(1 PYRROLIDINYL) 4 PYRIMIDINYL] 1 PIPERAZINYL]PREGNA 1,4,9(11) TRIENE 3,20 DIONE; 21 AMINOSTEROID; NEUROMODULIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE;

EID: 0343396819     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1020918310281     Document Type: Article
Times cited : (18)

References (54)
  • 1
    • 0002856038 scopus 로고
    • Hereditary progresive neurogeic muscular atrophy in the mouse
    • London
    • Duchen, L. W., Falconer, D. S., and Stricht, S. J. 1966. Hereditary progresive neurogeic muscular atrophy in the mouse. J. Physiol. (London) 183:53P-55P.
    • (1966) J. Physiol. , vol.183
    • Duchen, L.W.1    Falconer, D.S.2    Stricht, S.J.3
  • 2
    • 0020429617 scopus 로고
    • Murine motor neuron disease (the Wobbler mouse): Degeneration and regeneration of the lower motor neuron
    • Mitsumoto, H., and Bradley, W. G. 1982. Murine motor neuron disease (the Wobbler mouse): degeneration and regeneration of the lower motor neuron. Brain Res. 105:811-834.
    • (1982) Brain Res. , vol.105 , pp. 811-834
    • Mitsumoto, H.1    Bradley, W.G.2
  • 3
    • 0343954580 scopus 로고
    • Animal model: Motor neuron disease in the wobbler (wr/wr) mouse
    • Leetsma, J. E. 1980. Animal model: Motor neuron disease in the wobbler (wr/wr) mouse. Am. J. Pathol. 100:811-814.
    • (1980) Am. J. Pathol. , vol.100 , pp. 811-814
    • Leetsma, J.E.1
  • 4
    • 0026619935 scopus 로고
    • Spiny interneurons identified in the normal mouse spinal cord shows alterations in the Wobbler mouse: A model for inherited motoeuron disease
    • Ma, W., and Vacca-Galloway, L. L. 1982. Spiny interneurons identified in the normal mouse spinal cord shows alterations in the Wobbler mouse: a model for inherited motoeuron disease. Rest. Neurol. Neurosci. 4:381-392.
    • (1982) Rest. Neurol. Neurosci. , vol.4 , pp. 381-392
    • Ma, W.1    Vacca-Galloway, L.L.2
  • 5
    • 0025781843 scopus 로고
    • Reduced branching and lenght of dendrites detected in cervical spial cord motoneurons of wobbler mouse, a model for inherited motoneuron disease
    • Ma, W., and Vacca-Galloway, L. L. 1991. Reduced branching and lenght of dendrites detected in cervical spial cord motoneurons of wobbler mouse, a model for inherited motoneuron disease. J. Comp. Neurol. 311:210-222.
    • (1991) J. Comp. Neurol. , vol.311 , pp. 210-222
    • Ma, W.1    Vacca-Galloway, L.L.2
  • 6
    • 0028316075 scopus 로고
    • Abnormal astrocyte differentiation and defective cellular interactions in wobbler mouse spinal cord
    • Hantaz-Ambroise, D., Blondet, B., Murawsky, M., and Rieger, F. 1994. Abnormal astrocyte differentiation and defective cellular interactions in wobbler mouse spinal cord. J. Neurocytol. 23:179-192.
    • (1994) J. Neurocytol. , vol.23 , pp. 179-192
    • Hantaz-Ambroise, D.1    Blondet, B.2    Murawsky, M.3    Rieger, F.4
  • 7
    • 0030063311 scopus 로고    scopus 로고
    • The 21-aminosteroid U-74389F increases the number of glial fibrillary acidid protein-expressing astrocytes in the spinal cord of wobbler mice
    • Gonzalez Deniselle, M. C., Gonzalez, S., Piroli, G., Lima, A., and De Nicola, A. F. 1996. The 21-aminosteroid U-74389F increases the number of glial fibrillary acidid protein-expressing astrocytes in the spinal cord of wobbler mice. Cell Mol. Neurobiol. 16:61-72.
    • (1996) Cell Mol. Neurobiol. , vol.16 , pp. 61-72
    • Gonzalez Deniselle, M.C.1    Gonzalez, S.2    Piroli, G.3    Lima, A.4    De Nicola, A.F.5
  • 9
    • 4244070675 scopus 로고    scopus 로고
    • The antioxidant steroid U-74389F attenuates hyperexpression of GAP-43 in wobbler mouse, an animal model for amyotrophic lateral sclerosis (ALS)
    • González-Deniselle M. C., González S. L., Lima A., and De Nicola A. F. 1997. The antioxidant steroid U-74389F attenuates hyperexpression of GAP-43 in wobbler mouse, an animal model for amyotrophic lateral sclerosis (ALS). J. Neurol. Sci. 150:8139.
    • (1997) J. Neurol. Sci. , vol.150 , pp. 8139
    • González-Deniselle, M.C.1    González, S.L.2    Lima, A.3    De Nicola, A.F.4
  • 10
    • 0027343539 scopus 로고
    • Steroid hormones and neuronal regeneration
    • De Nicola, A. F. 1993. Steroid hormones and neuronal regeneration. Adv. Neurol. 59:199-206.
    • (1993) Adv. Neurol. , vol.59 , pp. 199-206
    • De Nicola, A.F.1
  • 11
    • 0021255932 scopus 로고
    • Effects of multidose methylprednisolone sodium succinate administration on injured cat spinal cord neurofilamente degradation ad energy metabolism
    • Braughler, J. M., and Hall, E. D. 1984. Effects of multidose methylprednisolone sodium succinate administration on injured cat spinal cord neurofilamente degradation ad energy metabolism. J. Neurosurg. 61:290-295.
    • (1984) J. Neurosurg. , vol.61 , pp. 290-295
    • Braughler, J.M.1    Hall, E.D.2
  • 12
    • 0027365090 scopus 로고
    • Neuroprotective actions of glucocorticoid and non-glucocorticoid steroids in acute neuronal injury
    • Hall, E. D. 1993. Neuroprotective actions of glucocorticoid and non-glucocorticoid steroids in acute neuronal injury. Cell. Mol. Neurobiol. 13:415-432.
    • (1993) Cell. Mol. Neurobiol. , vol.13 , pp. 415-432
    • Hall, E.D.1
  • 14
    • 0027496238 scopus 로고
    • A radical hypothesis for neurodegeneration
    • Olanow, C. W. 1993. A radical hypothesis for neurodegeneration. TINS 16:439-444.
    • (1993) TINS , vol.16 , pp. 439-444
    • Olanow, C.W.1
  • 15
    • 0027359334 scopus 로고
    • Superoxide dismutase activity, oxidative damage and mitochondrial energy metabolism in familial and sporadic amyotrophic lateral sclerosis
    • Bowling, A. C., Schulz, J. B., Brown, R. H., and Beal, M. F., 1993. Superoxide dismutase activity, oxidative damage and mitochondrial energy metabolism in familial and sporadic amyotrophic lateral sclerosis. J. Neurochem. 61:2322-2325.
    • (1993) J. Neurochem. , vol.61 , pp. 2322-2325
    • Bowling, A.C.1    Schulz, J.B.2    Brown, R.H.3    Beal, M.F.4
  • 16
    • 0030887358 scopus 로고    scopus 로고
    • Protective effect of a novel free-radical scavenger, OPC-14117, on wobbler mouse motor neuron disease
    • Abe, K., Morita, S., Kikuchi, T. Itoyama, Y. 1997. Protective effect of a novel free-radical scavenger, OPC-14117, on wobbler mouse motor neuron disease. J. Neurosci. Res. 48:63-70.
    • (1997) J. Neurosci. Res. , vol.48 , pp. 63-70
    • Abe, K.1    Morita, S.2    Kikuchi, T.3    Itoyama, Y.4
  • 17
    • 0029064788 scopus 로고
    • Lecithinized superoxide dismutase retards wobbler mouse motoneuron disease
    • Ikeda, K., Kinoshita, M., Iwasaki, Y., Tagaya, N., and Shiojima, T. 1995. Lecithinized superoxide dismutase retards wobbler mouse motoneuron disease. Neuromusc. Disord. 5:383-390.
    • (1995) Neuromusc. Disord. , vol.5 , pp. 383-390
    • Ikeda, K.1    Kinoshita, M.2    Iwasaki, Y.3    Tagaya, N.4    Shiojima, T.5
  • 18
    • 0029958252 scopus 로고    scopus 로고
    • Reduction of lower motor neuron degeneration in wobbler mice by n-acetyl-1-cysteine
    • Henderson, J. T., Javaheri, M., Kopko, S., and Roder, J. C. 1996. Reduction of lower motor neuron degeneration in wobbler mice by n-acetyl-1-cysteine. J. Neurosci. 16:7574-7582.
    • (1996) J. Neurosci. , vol.16 , pp. 7574-7582
    • Henderson, J.T.1    Javaheri, M.2    Kopko, S.3    Roder, J.C.4
  • 19
    • 0031027044 scopus 로고    scopus 로고
    • GAP-43: An intrinsic determinant of neuronal development and plasticity
    • Benowitz, L. I., and Routtenberg, A. 1997. GAP-43: an intrinsic determinant of neuronal development and plasticity. TINS 20:84-91.
    • (1997) TINS , vol.20 , pp. 84-91
    • Benowitz, L.I.1    Routtenberg, A.2
  • 21
    • 0027407746 scopus 로고
    • Up-regulation of GAP-43 and growth of axons in rat spinal cord after compression injury
    • Curtis, R., Green, D., Iindsay, R. m., and Wilkin, G. P. 1993. Up-regulation of GAP-43 and growth of axons in rat spinal cord after compression injury. J. Neurocytol. 22:51-64.
    • (1993) J. Neurocytol. , vol.22 , pp. 51-64
    • Curtis, R.1    Green, D.2    Iindsay, R.M.3    Wilkin, G.P.4
  • 22
    • 0031080386 scopus 로고    scopus 로고
    • RTPM-2 expression and tunel staining in neurodegenerative diseases: Studies in wobbler and rd mice
    • Popper, P., Farber, D. B., Micevych, P. E., Minoofar, K., and Bronstein, J. M. 1997. RTPM-2 expression and tunel staining in neurodegenerative diseases: studies in wobbler and rd mice. Exp. Neurol. 143:246-254.
    • (1997) Exp. Neurol. , vol.143 , pp. 246-254
    • Popper, P.1    Farber, D.B.2    Micevych, P.E.3    Minoofar, K.4    Bronstein, J.M.5
  • 23
    • 0027998283 scopus 로고
    • Differential localization of neuronal nitric oxide synthase immunoreactivity and NADPH-diaphorase activity in the cat spinal cord
    • Vizzard, M. A., Erdman, S. L., Roppolo, J. R., Forstermann, U., and de Groat, W. C. 1994. Differential localization of neuronal nitric oxide synthase immunoreactivity and NADPH-diaphorase activity in the cat spinal cord. Cell Tissue Res. 278:299-309.
    • (1994) Cell Tissue Res. , vol.278 , pp. 299-309
    • Vizzard, M.A.1    Erdman, S.L.2    Roppolo, J.R.3    Forstermann, U.4    De Groat, W.C.5
  • 24
    • 0030582411 scopus 로고    scopus 로고
    • Expression of nitric oxide synthase byt motor neurons in the spinal cord of the mutant mouse wobbler
    • Clowry, G. J., and McHanwell, S. 1996. Expression of nitric oxide synthase byt motor neurons in the spinal cord of the mutant mouse wobbler. Neurosci. Lett. 215:177-180.
    • (1996) Neurosci. Lett. , vol.215 , pp. 177-180
    • Clowry, G.J.1    McHanwell, S.2
  • 25
    • 0027759805 scopus 로고
    • Neuronal growth cone collapse and inhibition of protein fatty acylation by nitric oxide
    • Hess, D. T., Patterson, S. I., Smith, D. S., and Skene, J. H. P. 1993., Neuronal growth cone collapse and inhibition of protein fatty acylation by nitric oxide. Nature 366:562-565.
    • (1993) Nature , vol.366 , pp. 562-565
    • Hess, D.T.1    Patterson, S.I.2    Smith, D.S.3    Skene, J.H.P.4
  • 26
    • 0026744114 scopus 로고
    • Changes of neuropeptides in spinal cord and brain stem of Wobbler mouse at different stages of motoneuron disease
    • Yung, K. K. L., Tang, F., and Vacca-Galloway, L. L. 1992. Changes of neuropeptides in spinal cord and brain stem of Wobbler mouse at different stages of motoneuron disease. Neuroscience 50:209-222.
    • (1992) Neuroscience , vol.50 , pp. 209-222
    • Yung, K.K.L.1    Tang, F.2    Vacca-Galloway, L.L.3
  • 27
    • 0029814736 scopus 로고    scopus 로고
    • Bcl-2 sensitivity differentiates two pathways for motoneuronal death in the wobbler mutant mouse
    • Coulpier, M., Junier, M-P., Peschanski, M., and Dreyfus, P. A. 1996. Bcl-2 sensitivity differentiates two pathways for motoneuronal death in the wobbler mutant mouse. J. Neurosci. 16:5897-5904.
    • (1996) J. Neurosci. , vol.16 , pp. 5897-5904
    • Coulpier, M.1    Junier, M.-P.2    Peschanski, M.3    Dreyfus, P.A.4
  • 28
    • 0025899227 scopus 로고
    • Down-regulation of GAP-43 during oligodendrocyte development and lack of expression by astrocytes in vivo: Implications for macroglial differentiation
    • Curtis, R., Hardy, R., Reynolds, R., Spruce, B. A., and Wilkin, G. 1991. Down-regulation of GAP-43 during oligodendrocyte development and lack of expression by astrocytes in vivo: implications for macroglial differentiation. Eur. J. Neurosci. 3:876-886.
    • (1991) Eur. J. Neurosci. , vol.3 , pp. 876-886
    • Curtis, R.1    Hardy, R.2    Reynolds, R.3    Spruce, B.A.4    Wilkin, G.5
  • 29
    • 77049166450 scopus 로고
    • A cytoarchitectonic atlas of the spinal cord of the rat
    • Rexed, B. 1954. A cytoarchitectonic atlas of the spinal cord of the rat. J. Comp. Neurol. 100:297-380.
    • (1954) J. Comp. Neurol. , vol.100 , pp. 297-380
    • Rexed, B.1
  • 30
    • 0028858564 scopus 로고
    • Estradiol abolishes autologous regulation of glucocorticoid receptors in brain
    • Ferrini, M., Lima, A., and De Nicola, A. F. 1995. Estradiol abolishes autologous regulation of glucocorticoid receptors in brain. Life Sci. 57:2403-2412.
    • (1995) Life Sci. , vol.57 , pp. 2403-2412
    • Ferrini, M.1    Lima, A.2    De Nicola, A.F.3
  • 31
    • 0030774774 scopus 로고    scopus 로고
    • Aldosterone up-regulates mRNA for the α3 and β1 isoforms of (Na,K)-ATPase in several brain regions from adrenalectomized rats
    • Grillo, C., Piroli, G., Lima, A., McEwen, B. S., and De Nicola, A. F. 1997. Aldosterone up-regulates mRNA for the α3 and β1 isoforms of (Na,K)-ATPase in several brain regions from adrenalectomized rats. Brain Res. 767:120-127.
    • (1997) Brain Res. , vol.767 , pp. 120-127
    • Grillo, C.1    Piroli, G.2    Lima, A.3    McEwen, B.S.4    De Nicola, A.F.5
  • 32
    • 0026684776 scopus 로고
    • Immunocytochemical detection of the growth-associated protein B-50 by newly characterized monoclonal antibodies in human brain and muscle
    • Mercken, M., Lubke, U., Vandermeeren, M., Gheuens, J., and Oestreicher, A. B. 1992. Immunocytochemical detection of the growth-associated protein B-50 by newly characterized monoclonal antibodies in human brain and muscle. J. Neurobiol. 23:309-321.
    • (1992) J. Neurobiol. , vol.23 , pp. 309-321
    • Mercken, M.1    Lubke, U.2    Vandermeeren, M.3    Gheuens, J.4    Oestreicher, A.B.5
  • 33
    • 0026566724 scopus 로고
    • GAP-43 immunoreactivity is widespread in the autonomie neurons and sensory neurons of the rat
    • Stewart, H. J. S., Cowen, T., Curtis, R., Wilkin, G. P., Mirsky, R., and Jessen, K. R. 1992. GAP-43 immunoreactivity is widespread in the autonomie neurons and sensory neurons of the rat. Neurosci. 47:673-684.
    • (1992) Neurosci. , vol.47 , pp. 673-684
    • Stewart, H.J.S.1    Cowen, T.2    Curtis, R.3    Wilkin, G.P.4    Mirsky, R.5    Jessen, K.R.6
  • 34
    • 0030792922 scopus 로고    scopus 로고
    • Constitutive expression of calmodulin-binding phosphoprotein GAP-43 in rat serotonergic and noradrenergic cell groups which project to the spinal cord
    • Wotherspoon, G., Lopez-Costa, J. J., Michael, G. J., and Priestley, J. V. 1997. Constitutive expression of calmodulin-binding phosphoprotein GAP-43 in rat serotonergic and noradrenergic cell groups which project to the spinal cord. Neurochem. Res. 22:985-993.
    • (1997) Neurochem. Res. , vol.22 , pp. 985-993
    • Wotherspoon, G.1    Lopez-Costa, J.J.2    Michael, G.J.3    Priestley, J.V.4
  • 35
    • 0028865363 scopus 로고
    • Aberrant GAP-43 gene expression in Alzheimer's disease
    • De la Monte, S. M., Ng, S-C., and Hsu, D. W. 1995. Aberrant GAP-43 gene expression in Alzheimer's disease. Am. J. Pathol. 147:934-946.
    • (1995) Am. J. Pathol. , vol.147 , pp. 934-946
    • De La Monte, S.M.1    Ng, S.-C.2    Hsu, D.W.3
  • 36
    • 0022624004 scopus 로고
    • Impaired slow axonal transport in wobbler mouse motor neuron disease
    • Mitsumoto, H., and Gambetti, P. 1986. Impaired slow axonal transport in wobbler mouse motor neuron disease. An. Neurol. 19:36-43.
    • (1986) An. Neurol. , vol.19 , pp. 36-43
    • Mitsumoto, H.1    Gambetti, P.2
  • 37
    • 0028069601 scopus 로고
    • Inverse patterns of myelination and GAP-43 expression in the dault CNS: Neurite growth inhibitors as regulators of neuronal plasticity ?
    • Kapfhammer, J. P., and Schwab, M. E. 1994. Inverse patterns of myelination and GAP-43 expression in the dault CNS: neurite growth inhibitors as regulators of neuronal plasticity ?. J. Comp. Neurol. 340:194-206.
    • (1994) J. Comp. Neurol. , vol.340 , pp. 194-206
    • Kapfhammer, J.P.1    Schwab, M.E.2
  • 38
    • 0024259870 scopus 로고
    • Dual regulation of GAP-43 gene expression by nerve growth factor and glucocorticoids
    • Federoff, H. J., Grabczyk, E., and Fishman, M. C. 1988. Dual regulation of GAP-43 gene expression by nerve growth factor and glucocorticoids. J. Biol. Chem. 263:19290-19295.
    • (1988) J. Biol. Chem. , vol.263 , pp. 19290-19295
    • Federoff, H.J.1    Grabczyk, E.2    Fishman, M.C.3
  • 39
    • 0027067094 scopus 로고
    • The expression of growth-associated protein GAP-43 mRNA in the rat hippocampus in response to adrenalectomy and aging
    • Chao, H. M., Spencer, R. L., Sakai, R. R., and McEwen, B. S. 1992. The expression of growth-associated protein GAP-43 mRNA in the rat hippocampus in response to adrenalectomy and aging. Mol. Cell. Neurosci. 3:529-535.
    • (1992) Mol. Cell. Neurosci. , vol.3 , pp. 529-535
    • Chao, H.M.1    Spencer, R.L.2    Sakai, R.R.3    McEwen, B.S.4
  • 41
    • 0027193760 scopus 로고
    • Nitric oxide synthase immunoreactivity in the rat, mouse, cat and squirrel monkey spinal cord
    • Dun, N. J., Dun, S. L., Wu, S. Y., Forsterman, U., Schmidt, H. H. H. W., and Tseng, L. F. 1993. Nitric oxide synthase immunoreactivity in the rat, mouse, cat and squirrel monkey spinal cord. Neurosci. 54:845-857.
    • (1993) Neurosci. , vol.54 , pp. 845-857
    • Dun, N.J.1    Dun, S.L.2    Wu, S.Y.3    Forsterman, U.4    Schmidt, H.H.H.W.5    Tseng, L.F.6
  • 42
    • 0027154946 scopus 로고
    • Expression of nitric oxide synthase (NOS) in injured CNS neurons as shown by histochemistry for NADPH-diaphorase
    • Wu, W. 1993. Expression of nitric oxide synthase (NOS) in injured CNS neurons as shown by histochemistry for NADPH-diaphorase. Exp. Neurol. 120:153-159.
    • (1993) Exp. Neurol. , vol.120 , pp. 153-159
    • Wu, W.1
  • 43
    • 0027490697 scopus 로고
    • Nitric oxide: Foe or friend to the injured brain ?
    • Choi, D. W. 1993. Nitric oxide: foe or friend to the injured brain ?. Proc. Natl. Acad. Sci. USA 90:9741-9743.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 9741-9743
    • Choi, D.W.1
  • 44
    • 0345505966 scopus 로고
    • Localization of nitric oxide synthase: Alterations in disease
    • Buttery, L. D. K., and Polak, J. M. 1995. Localization of nitric oxide synthase: alterations in disease. Current Diag. Pathol. 2:111-121.
    • (1995) Current Diag. Pathol. , vol.2 , pp. 111-121
    • Buttery, L.D.K.1    Polak, J.M.2
  • 45
    • 0029989846 scopus 로고    scopus 로고
    • Nitric oxide synthase inhibitors
    • Resink, A., Dawson, V. L., and Dawson, T. D. 1996. Nitric oxide synthase inhibitors. CNS Drugs 6:351-367.
    • (1996) CNS Drugs , vol.6 , pp. 351-367
    • Resink, A.1    Dawson, V.L.2    Dawson, T.D.3
  • 46
    • 0028092958 scopus 로고
    • Nitric oxide synthases: Roles, tolls and controls
    • Nathan, C., and Xie, Q-W. 1994. Nitric oxide synthases: roles, tolls and controls. Cell 78:915-918.
    • (1994) Cell , vol.78 , pp. 915-918
    • Nathan, C.1    Xie, Q.-W.2
  • 47
    • 0026492689 scopus 로고
    • Excitatory amino acid receptor antagonist in murine motoneuron disease (the wobbler mouse)
    • Krieger, C., Perry, T. L., Hanse, S., Mitsumoto, H., and Honoré, T. 1992. Excitatory amino acid receptor antagonist in murine motoneuron disease (the wobbler mouse). Can. J. Neurol. 19:462-465.
    • (1992) Can. J. Neurol. , vol.19 , pp. 462-465
    • Krieger, C.1    Perry, T.L.2    Hanse, S.3    Mitsumoto, H.4    Honoré, T.5
  • 48
    • 0030067834 scopus 로고    scopus 로고
    • Nitric oxide in neuronal degeneration
    • Dawson, V. L., and Dawson, T. M. 1996. Nitric oxide in neuronal degeneration. FASEB J. :33-40.
    • (1996) FASEB J. , pp. 33-40
    • Dawson, V.L.1    Dawson, T.M.2
  • 49
    • 0029066333 scopus 로고
    • Traumatic neuronal injury in cortical cell culture is attenuated by 21-aminosteroids
    • Regan, R. F., and Panter, S. S. 1995. Traumatic neuronal injury in cortical cell culture is attenuated by 21-aminosteroids. Brain Res. 682:144-150.
    • (1995) Brain Res. , vol.682 , pp. 144-150
    • Regan, R.F.1    Panter, S.S.2
  • 50
    • 0028842349 scopus 로고
    • The potential of 21-aminosteroids (Lazaroids) as neuroprotective therapies in CNS injury
    • Smith, D. H., Gennarelly, T. A., and Mcintosh, T. K. 1995. The potential of 21-aminosteroids (Lazaroids) as neuroprotective therapies in CNS injury. CNS Drugs 3:159-164.
    • (1995) CNS Drugs , vol.3 , pp. 159-164
    • Smith, D.H.1    Gennarelly, T.A.2    Mcintosh, T.K.3
  • 51
    • 0028000719 scopus 로고
    • Lewis rat EAN is suppressed by the 21-aminosteroid tirilazad mesylate (U-74006F)
    • Feasby, T. E., Hahn, A. F., Lovgren, D., and Wilkie, L. 1994. Lewis rat EAN is suppressed by the 21-aminosteroid tirilazad mesylate (U-74006F). Neuropathol. Applied Neurobiol. 20:384-391.
    • (1994) Neuropathol. Applied Neurobiol. , vol.20 , pp. 384-391
    • Feasby, T.E.1    Hahn, A.F.2    Lovgren, D.3    Wilkie, L.4
  • 52
    • 0024518123 scopus 로고
    • The 21-aminosteroids: Potent inhibitors of lipid peroxidation for the treatment of central nervous system trauma and ischemia
    • Braughler, J. M., Hall, E. D., Jacobsen, E. J., McCall, J. M., and Means, E. D. 1989. The 21-aminosteroids: potent inhibitors of lipid peroxidation for the treatment of central nervous system trauma and ischemia. Drugs of the Future 14:143-152.
    • (1989) Drugs of the Future , vol.14 , pp. 143-152
    • Braughler, J.M.1    Hall, E.D.2    Jacobsen, E.J.3    McCall, J.M.4    Means, E.D.5
  • 53
    • 0028129115 scopus 로고
    • Biphasic effect of estrogen on neuronal constitutive nitric oxide synthase via Ca2+-calmodulin dependent mechanism
    • Hayashi, T., Ishikawa, T., Yamada, K., Kuzuya, M., Naito, M., Hidaka, H., and Iguchi, A. 1994. Biphasic effect of estrogen on neuronal constitutive nitric oxide synthase via Ca2+-calmodulin dependent mechanism. Biochem. Biophys. Res. Commun. 203:1013-1019.
    • (1994) Biochem. Biophys. Res. Commun. , vol.203 , pp. 1013-1019
    • Hayashi, T.1    Ishikawa, T.2    Yamada, K.3    Kuzuya, M.4    Naito, M.5    Hidaka, H.6    Iguchi, A.7
  • 54
    • 0030318851 scopus 로고    scopus 로고
    • GAP-43: Putting constrains on neuronal plasticity
    • Fishman, M. 1996. GAP-43: putting constrains on neuronal plasticity. Persp. Dev. Neurobiol. 4:193-198.
    • (1996) Persp. Dev. Neurobiol. , vol.4 , pp. 193-198
    • Fishman, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.