Single values of serum transferrin receptor and transferrin receptor ferritin index can be used to detect true and functional iron deficiency in rheumatoid arthritis patients with anemia

Arthritis and Rheumatism

Volumn 43, Issue 5, 2000, Pages 1016-1020

  Suominen, Pauli ^a   Möttönen, Timo ^a   Rajamäki, Allan ^a   Irjala, Kerttu ^a  

^a TURKU UNIVERSITY HOSPITAL   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

FERRITIN; TRANSFERRIN RECEPTOR;

ADULT; AGED; ANEMIA; ARTICLE; CHRONIC DISEASE; CLINICAL ARTICLE; DIAGNOSTIC APPROACH ROUTE; DIAGNOSTIC VALUE; DIFFERENTIAL DIAGNOSIS; DISEASE ASSOCIATION; FEMALE; HUMAN; IRON DEFICIENCY ANEMIA; IRON STORAGE; MALE; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; TRANSFERRIN BLOOD LEVEL;

ANEMIA, IRON-DEFICIENCY; ARTHRITIS, RHEUMATOID; BODY MASS INDEX; FERRITINS; HEMATOCRIT; HEMOGLOBINS; HUMANS; IRON; RECEPTORS, TRANSFERRIN;

EID: 0342804270     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/1529-0131(200005)43:5<1016::AID-ANR9>3.0.CO;2-3     Document Type: Article

References (15)

1. Means RT Jr, Krantz SB. Progress in understanding the pathogenesis of the anemia of chronic disease. Blood 1992;80:1639-47.
2. Weiss G, Wachter H, Fuchs D. Linkage of cell-mediated immunity to iron metabolism. Immunol Today 1995;16:495-500.
3. Cazzola M, Mercuriali F, Brugnara C. Use of recombinant human erythropoietin outside the setting of uremia. Blood 1997;89:4248-67.
4. Beguin Y. Prediction of response to optimize outcome of treatment with erythropoietin. Semin Oncol 1998;25:27-34.
5. Brugnara C, Chambers LA, Malynn E, Goldberg MA, Kruskall MS. Red blood cell regeneration induced by subcutaneous recombinant erythropoietin: iron-deficient erythropoiesis in iron-replete subjects. Blood 1993;81:956-64.
6. Ferguson BJ, Skikne BS, Simpson KM, Baynes RD, Cook JD. Serum transferrin receptor distinguishes the anemia of chronic disease from iron deficiency anemia. J Lab Clin Med 1992;119: 385-90.
7. Punnonen K, Irjala K, Rajamaki A. Serum transferrin receptor and its ratio to serum ferritin in the diagnosis of iron deficiency. Blood 1997;89:1052-7.
8. Suominen P, Punnonen K, Rajamaki A, Majuri R, Hanninen V, Irjala K. Automated immunoturbidimetric method for measuring serum transferrin receptor. Clin Chem 1999;45:1302-5.
9. Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988;31:315-24.
10. Prevoo MLL, van 't Hof MA, Kuper HH, van Leeuwen MA, van de Putte LBA, van Riel PLCM. Modified disease activity scores that include twenty-eight-joint counts: development and validation in a prospective longitudinal study of patients with rheumatoid arthritis. Arthritis Rheum 1995;38:44-8.
11. Goodnough LT, Monk TG, Andriole GL. Erythropoietin therapy. N Engl J Med 1997;336:933-8.
12. Price TH, Goodnough LT, Vogler WR, Sacher RA, Hellman RM, Johnston MF, et al. The effect of recombinant human erythropoietin on the efficacy of autologous blood donation in patients with low hematocrits: a multicenter, randomized, double-blind, controlled trial. Transfusion 1996;36:29-36.
13. Wingard RL, Parker RA, Ismail N, Hakim RM. Efficacy of oral iron therapy in patients receiving recombinant human erythropoietin. Am J Kidney Dis 1995;25:433-9.
14. Suominen P, Punnonen K, Rajamaki A, Irjala K. Serum transferrin receptor and transferrin receptor-ferritin index identify healthy subjects with subclinical iron deficits. Blood 1998;92: 2934-9.
15. Guillen C, McInnes IB, Kruger H, Brock JH. Iron, lactoferrin and iron regulatory protein activity in the synovium: relative importance of iron loading and the inflammatory response. Ann Rheum Dis 1998;57:309-14.